Abstract:
Background:Prevalence of subungual melanoma (SUM) in Asian population is relatively high and early clinical detection improves both quality of life and survival. Objective:We sought to establish screening strategy for SUM in situ. Methods:We retrospectively reviewed medical records of 8 patients pathologically diagnosed as SUM in situ between January 2015 and September 2016. Results:All patients in our study were adults and had solitary lesion. In all cases, longitudinal melanonychia as well as background pigmentation in entire nail plate was observed. Seven (87.5%) cases had periungual pigmentation. Clinical features of SUM in situ can be summarized according to new criteria categorized under initial letters of alphabet, namely nail ABCD of SUM in situ; "A" stands for adult age (age >18 years); "B" for brown bands in brown background; "C" for color in periungual skin; "D" for one digit. Our strategy was to suspect SUM in situ if solitary longitudinal melanonychia in adult was satisfying either "B" or "C" in ABCD. All cases were suspected as SUM in situ under nail ABCD rule, and histological examination confirmed diagnosis. Sensitivity and specificity of nail ABCD was 100% and 96.6%, respectively, regarding our previously published 18 SUM in situ and unpublished 28 nail matrix nevi cases as well as 8 SUM in situ presented here. Conclusion:ABCD rule is simple and sensitive clinical strategy for early detection of SUM in situ.
journal_name
Ann Dermatoljournal_title
Annals of dermatologyauthors
Lee JH,Park JH,Lee JH,Lee DYdoi
10.5021/ad.2018.30.1.36subject
Has Abstractpub_date
2018-02-01 00:00:00pages
36-40issue
1eissn
1013-9087issn
2005-3894journal_volume
30pub_type
杂志文章abstract:BACKGROUND:Computer-aided image analysis (CAIA) has been suggested as an effective diagnostic tool for pigmented skin lesions (PSLs), especially melanoma. However, few studies on benign PSLs have been reported. OBJECTIVE:The purpose of this study was to evaluate benign PSLs with our CAIA software and analyze the diffe...
journal_title:Annals of dermatology
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abstract:BACKGROUND:The use of growth factors in skin rejuvenation is emerging as a novel anti-aging treatment. While the role of growth factors in wound healing is well established, their use in skin rejuvenation has only recently been to be studied and no controlled trials have been performed. OBJECTIVE:We evaluated the anti...
journal_title:Annals of dermatology
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doi:10.5021/ad.2014.26.5.584
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abstract::Acquired brachial cutaneous dyschromatosis (ABCD) is an acquired disorder of pigmentary change that presents as chronic, asymptomatic, geographic-shaped, gray-brown patches, consisting of mixed hyper and hypopigmented macules on the dorsal aspect of the forearms. We report a case of a 40-year-old male who presented wi...
journal_title:Annals of dermatology
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doi:10.5021/ad.2018.30.3.342
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abstract::Hydroa vacciniforme (HV) is a photosensitivity disorder characterized by recurrent necrotic vesiculopapules on sun-exposed areas, which heal spontaneously during adolescence. Recently, an association has been reported between latent Epstein-Barr virus (EBV) infection and atypical HV-like eruption and malignant potenti...
journal_title:Annals of dermatology
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doi:10.5021/ad.2009.21.2.209
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Through differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte differentiation is disturbed in several skin diseases such as psoriasis and atopic dermatitis. OBJECTIVE:The aim of this study i...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2010.22.3.255
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abstract::Membranous lipodystrophy is characterized by the presence of microcysts lined by amorphous, eosinophilic material with an arabesque appearance. We experienced a case of a 72-year-old man who had dark brownish, pruritic papules on the arms, legs, and back. Histopathologic examination of a biopsied lesion showed homogen...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.2.174
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abstract:BACKGROUND:Progressive macular hypomelanosis is characterized by ill-defined, non-scaly, hypopigmented macules primarily on the trunk of the body. Although numerous cases of progressive macular hypomelanosis have been reported, there have been no clinicopathologic studies of progressive macular hypomelanosis in Korean ...
journal_title:Annals of dermatology
pub_type: 杂志文章
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更新日期:2009-08-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.4.431
更新日期:2014-08-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.2.189
更新日期:2013-05-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.6.722
更新日期:2017-12-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.1.6
更新日期:2017-02-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2014.26.1.79
更新日期:2014-02-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.4.434
更新日期:2013-11-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2017.29.2.143
更新日期:2017-04-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.3.300
更新日期:2009-08-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2008.20.1.11
更新日期:2008-03-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2013.25.1.23
更新日期:2013-02-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2012.24.1.74
更新日期:2012-02-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2009.21.1.63
更新日期:2009-02-01 00:00:00
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journal_title:Annals of dermatology
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doi:10.5021/ad.2010.22.2.219
更新日期:2010-05-01 00:00:00
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journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2011.23.1.33
更新日期:2011-02-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.3.358
更新日期:2010-08-01 00:00:00
abstract::Sarcoidosis is a systemic inflammatory disease of an unknown origin and it is characterized by the presence of noncaseating epitheloid cell granulomas in multiple organs. Herein we report on a case of cutaneous and pulmonary sarcoidosis that was associated with interferon alpha treatment for hepatitis C. A 39-year-old...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2011.23.2.239
更新日期:2011-05-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2015.27.4.431
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Hair loss and hair growth is the subject of tremendous amount of research. OBJECTIVE:This study investigated the efficacy of three chemical treatments used in humans for hair loss, using a rat model of hair regrowth. The products tested were 2% minoxidil, Hairgrow (Dar-Al-Dawa Pharma), Aminexil, Dercos (Vic...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.1.65
更新日期:2016-02-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2010.22.4.456
更新日期:2010-11-01 00:00:00
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journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2013.25.3.352
更新日期:2013-08-01 00:00:00
abstract::Leiomyosarcomas are uncommon malignant smooth muscle tumors, mainly derived from vessels or viscera. Superficial leiomyosarcomas are a rare soft tissue sarcoma arising from the dermis or subcutaneous tissue in the skin. According to tumor origin and location, they are divided into cutaneous and subcutaneous leiomyosar...
journal_title:Annals of dermatology
pub_type:
doi:10.5021/ad.2013.25.2.237
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:The atopic dermatitis (AD) can limit a patient's physical and psychosocial development as well as lower their overall quality of life (QOL), including sleep quality. OBJECTIVE:The purpose of this study was to evaluate the relationships between clinical disease severity, QOL and sleep quality in children and...
journal_title:Annals of dermatology
pub_type: 杂志文章
doi:10.5021/ad.2016.28.3.321
更新日期:2016-06-01 00:00:00