Endovascular management of renal artery aneurysms induced by neurofibromatosis type 1: A case report.

Abstract:

RATIONALE:Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder characterized by cafe au lait macules and neurofibromatosis. Renal artery aneurysms are relatively uncommon. Endovascular techniques are effective in treating renal aneurysms but successful cases are rarely reported in NF-1 adults. PATIENT CONCERNS:The patient was one 23-year-old female presented with hypertension, multiple café-au-lait spots ≥15 mm, and plexiform neurofibroma. Renal artery aneurysms were found by ultrasound. DIAGNOSES:NF-1 was diagnosed based on clinical manifestations and confirmed by gene test. Renal artery aneurysms were diagnosed based on computed tomography. INTERVENTIONS:Bilateral renal artery angiography was performed and 3 aneurysms were found sequentially on the left anterior superior segmental artery. Microcoil embolization of aneurysms was undertaken. OUTCOMES:The patient's blood pressure decreased after the procedure with reduction of medicine. A 3-month follow-up unilateral selective renal angiogram demonstrated little change in size of aneurysms, and no opacification of the aneurysmal sac was found. Serum creatinine remained in normal range at 3-month. LESSONS:Successful endovascular treatment for NF-1 related renal artery aneurysms in adults is reported for the 1st time with preserved renal function and improved hypertension. Endovascular procedure is considered to be feasible and effective for renal artery aneurysms induced by NF-1.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Zhang B,Zou Y,Yang M,Niu G

doi

10.1097/MD.0000000000008858

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

e8858

issue

47

eissn

0025-7974

issn

1536-5964

pii

00005792-201711270-00091

journal_volume

96

pub_type

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