Characterization of Conformational Ensembles of Protonated N-glycans in the Gas-Phase.

abstract：:Pluripotency can be induced in vitro from adult somatic mammalian cells by enforced expression of defined transcription factors regulating and initiating the pluripotency network. Despite the substantial advances over the last decade to improve the efficiency of direct reprogramming, exact mechanisms underlying the co...

journal_title：Scientific reports

authors： Raab S,Klingenstein M,Möller A,Illing A,Tosic J,Breunig M,Kuales G,Linta L,Seufferlein T,Arnold SJ,Kleger A,Liebau S

更新日期：2017-11-29 00:00:00

abstract：:Traditional strengthening ways, such as strain, precipitation, and solid-solution, come into effect by pinning the motion of dislocation. Here, through first-principles calculations we report on an extra-electron induced covalent strengthening mechanism, which alters chemical bonding upon the introduction of extra-val...

journal_title：Scientific reports

authors： Niu H,Chen XQ,Liu P,Xing W,Cheng X,Li D,Li Y

更新日期：2012-01-01 00:00:00

abstract：:Geographically diverse samples from strawberry exhibiting symptoms of Strawberry Green Petal (SbGP), periwinkle plants with virescence, and blackberry, blueberry, and raspberry plants displaying yellowing and inedible fruits, were assayed for the presence of phytoplasma DNA. PCR targeting the 16S rRNA-encoding gene an...

journal_title：Scientific reports

authors： Pérez-López E,Rodríguez-Martínez D,Olivier CY,Luna-Rodríguez M,Dumonceaux TJ

更新日期：2017-04-19 00:00:00

abstract：:In this work, we introduce a novel and facile method of exfoliating large-area, single-layer graphene oxide using a shearing stress. The shearing stress reactor consists of two concentric cylinders, where the inner cylinder rotates at controlled speed while the outer cylinder is kept stationary. We found that the form...

journal_title：Scientific reports

authors： Park WK,Yoon Y,Song YH,Choi SY,Kim S,Do Y,Lee J,Park H,Yoon DH,Yang WS

更新日期：2017-11-27 00:00:00

abstract：:Therapies that target the signal transduction and metabolic pathways of cancer stem cells (CSCs) are innovative strategies to effectively reduce the recurrence and significantly improve the outcome of glioblastoma multiforme (GBM). CSCs exhibit an increased rate of glycolysis, thus rendering them intrinsically more se...

journal_title：Scientific reports

authors： Daniele S,Giacomelli C,Zappelli E,Granchi C,Trincavelli ML,Minutolo F,Martini C

更新日期：2015-10-23 00:00:00

abstract：:We report a strategy to achieve a discrete cage molecule featuring a high level of structural hierarchy through a multiple-assembly process. A cobalt (Co) supramolecular triple-stranded helicate (Co-TSH)-based discrete molecular cage (1) is successfully synthesized and fully characterized. The solid-state structure of...

journal_title：Scientific reports

authors： Mai HD,Kang P,Kim JK,Yoo H

更新日期：2017-03-06 00:00:00

abstract：:Replacing precious and nondurable Pt catalysts with cheap materials is a key issue for commercialization of fuel cells. In the case of oxygen reduction reaction (ORR) catalysts for direct methanol fuel cell (DMFC), the methanol tolerance is also an important concern. Here, we develop AlN nanowires with diameters of ab...

journal_title：Scientific reports

authors： Lei M,Wang J,Li JR,Wang YG,Tang HL,Wang WJ

更新日期：2014-08-11 00:00:00

abstract：:Neutrophil elastase (NE) suppresses IL-8/CXCL8 in human airway smooth muscle cells (hASM) while stimulating its production in respiratory epithelial cells. This differential effect is mediated by the selective induction of NKRF and dysregulation in chronic inflammatory diseases. We hypothesized that the differential a...

journal_title：Scientific reports

authors： Ho SC,Wu SM,Feng PH,Liu WT,Chen KY,Chuang HC,Chan YF,Kuo LW,Lee KY

更新日期：2017-03-21 00:00:00

abstract：:A coherent anti-Stokes Raman scattering (CARS) rigid endoscope was developed to visualize peripheral nerves without labeling for nerve-sparing endoscopic surgery. The developed CARS endoscope had a problem with low imaging speed, i.e. low imaging rate. In this study, we demonstrate that noise reduction with deep learn...

journal_title：Scientific reports

authors： Yamato N,Niioka H,Miyake J,Hashimoto M

更新日期：2020-09-16 00:00:00

abstract：:Microbeam radiation therapy is a novel preclinical technique, which uses synchrotron-generated X-rays for the treatment of brain tumours and drug-resistant epilepsies. In order to safely translate this approach to humans, a more in-depth knowledge of the long-term radiobiology of microbeams in healthy tissues is requi...

journal_title：Scientific reports

authors： Fardone E,Bravin A,Conti A,Bräuer-Krisch E,Requardt H,Bucci D,Le Duc G,Battaglia G,Romanelli P

更新日期：2017-10-30 00:00:00

abstract：:Optimized mesoporous photocatalyst endowed with high specific surface area and large pore size was synthesized by sol-gel method. These large pore mesoporous materials (33.39 nm) were conducive to the movement of larger molecules or groups in pore path and for effective use of active sites. The high specific surface a...

journal_title：Scientific reports

authors： Xue H,Jiang Y,Yuan K,Yang T,Hou J,Cao C,Feng K,Wang X

更新日期：2016-07-19 00:00:00

abstract：:Microorganisms associated with plants are highly diverse and can produce a large number of secondary metabolites, with antimicrobial, anti-parasitic and cytotoxic activities. We are particularly interested in exploring endophytes from medicinal plants found in the Pantanal, a unique and widely unexplored wetland in Br...

journal_title：Scientific reports

authors： Savi DC,Shaaban KA,Gos FMWR,Ponomareva LV,Thorson JS,Glienke C,Rohr J

更新日期：2018-02-15 00:00:00

abstract：:Twenty-six imprinted genes were quantified in bovine in vivo produced oocytes and embryos using RNA-seq. Eighteen were detectable and their transcriptional patterns were: largely decreased (MEST and PLAGL1); first decreased and then increased (CDKN1C and IGF2R); peaked at a specific stage (PHLDA2, SGCE, PEG10, PEG3, G...

journal_title：Scientific reports

authors： Jiang Z,Dong H,Zheng X,Marjani SL,Donovan DM,Chen J,Tian XC

更新日期：2015-12-07 00:00:00

abstract：:The importance of evaluating physical cues in cancer research is gradually being realized. Assessment of cancer cell physical appearance, or phenotype, may provide information on changes in cellular behavior, including migratory or communicative changes. These characteristics are intrinsically different between malign...

journal_title：Scientific reports

authors： Ware MJ,Tinger S,Colbert KL,Corr SJ,Rees P,Koshkina N,Curley S,Summers HD,Godin B

更新日期：2015-07-13 00:00:00

abstract：:Soldiers of some eusocial insects exhibit an altruistic self-destructive defense behavior in emergency situations when attacked by large enemies. The swarm-forming invasive millipede, Chamberlinius hualienensis, which is not classified as eusocial animal, exudes irritant chemicals such as benzoyl cyanide as a defensiv...

journal_title：Scientific reports

authors： Ishida Y,Kuwahara Y,Dadashipour M,Ina A,Yamaguchi T,Morita M,Ichiki Y,Asano Y

更新日期：2016-06-06 00:00:00

abstract：:Glutamine metabolism and the mechanistic target of rapamycin (mTOR) pathway are activated cooperatively in the differentiation and activation of inflammatory immune cells. But the combined inhibition of both pathways was rarely investigated. This study investigated how inhibiting both glutamine metabolism with 6-diazo...

journal_title：Scientific reports

authors： Ueda Y,Saegusa J,Okano T,Sendo S,Yamada H,Nishimura K,Morinobu A

更新日期：2019-04-23 00:00:00

abstract：:Epilepsy is a chronic neurological disease with a variable therapeutic response. To design effective treatment strategies for epilepsy, it is important to understand treatment responses and predictive factors. However, limited data are available in Africa, including Ethiopia. The aim of this study was therefore to ass...

journal_title：Scientific reports

authors： Gidey K,Chelkeba L,Gemechu TD,Daba FB

更新日期：2019-11-07 00:00:00

abstract：:TiO2 nanoribbons (TiO2 NRs) loaded with FeCo-Al2O3 catalyst were synthesized and used as a precursor in the synthesis of TiO2 nanoribbons/carbon nanotubes (TiO2 NRs/CNTs) composite by a chemical vapor deposition (CVD) method. TiO2 NRs and TiO2 NRs/CNTs composite were characterized by XRD, FT-IR, TEM, SEM, EDX and UV-V...

journal_title：Scientific reports

authors： Shaban M,Ashraf AM,Abukhadra MR

更新日期：2018-01-15 00:00:00

abstract：:Cross-talk between exogenous salicylic acid (SA) and endogenous phytohormone pathways affects the antioxidant defense system and its response to salt stress. The study presented here investigated the effects of SA treatment before and during salt stress on the levels of endogenous plant growth regulators in three barl...

journal_title：Scientific reports

authors： Torun H,Novák O,Mikulík J,Pěnčík A,Strnad M,Ayaz FA

更新日期：2020-08-17 00:00:00

abstract：:Ionotropic glutamate receptors (iGluRs) are responsible for most of the fast excitatory communication between neurons in our brain. The GluD2 receptor is a puzzling member of the iGluR family: It is involved in synaptic plasticity, plays a role in human diseases, e.g. ataxia, binds glycine and D-serine with low affini...

journal_title：Scientific reports

authors： Tapken D,Steffensen TB,Leth R,Kristensen LB,Gerbola A,Gajhede M,Jørgensen FS,Olsen L,Kastrup JS

更新日期：2017-04-07 00:00:00

abstract：:Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. Serum FGF23 levels are highly elevated in patients with chronic kidney disease ...

journal_title：Scientific reports

authors： Grabner A,Schramm K,Silswal N,Hendrix M,Yanucil C,Czaya B,Singh S,Wolf M,Hermann S,Stypmann J,Di Marco GS,Brand M,Wacker MJ,Faul C

更新日期：2017-05-16 00:00:00

abstract：:In this study, a model assisted strategy is developed to control the distribution of colloids in porous media in the framework of nanoremediation, an innovative environmental nanotechnology aimed at reclaiming contaminated aquifers. This approach is exemplified by the delivery of humic acid-stabilized iron oxide nanop...

journal_title：Scientific reports

authors： Bianco C,Patiño Higuita JE,Tosco T,Tiraferri A,Sethi R

更新日期：2017-10-11 00:00:00

abstract：:Diffusion processes are widespread in biological and chemical systems, where they play a fundamental role in the exchange of substances at the cellular level and in determining the rate of chemical reactions. Recently, the classical picture that portrays diffusion as random uncorrelated motion of molecules has been re...

journal_title：Scientific reports

authors： Cerbino R,Sun Y,Donev A,Vailati A

更新日期：2015-09-30 00:00:00

abstract：:To investigate the potential role of vitamin D (1,25(OH)2D3) in preventing the development of nasal polyps, we examined the effect of vitamin D on myofibroblast differentiation and extracellular matrix (ECM) production in TGF-β1-induced nasal polyp-derived fibroblasts (NPDFs) and elucidated the mechanisms underlying i...

journal_title：Scientific reports

authors： Lee SA,Yang HW,Um JY,Shin JM,Park IH,Lee HM

更新日期：2017-08-04 00:00:00

abstract：:To investigate the influence of chemical weathering on CO2 consumption, an analysis was performed of water chemistry by applying water chemistry equilibria methods in the Bishuiyan subterranean basin, SW China. The average value of total ion concentrations (TZ+) was 1,854.97 μEq/L, which was significantly higher than ...

journal_title：Scientific reports

authors： Jiang P,Yu G,Zhang Q,Zou Y,Tang Q,Kang Z,Sytharith P,Xiao H

更新日期：2020-07-15 00:00:00

abstract：:Clinical data from 172 cases of uterine fibroids with different appearances on MRI-T2WI and accepted ultrasound guided high intensity focused ultrasound (USgHIFU) treatment were retrospectively analyzed. This study aimed to evaluate the clinical safety and efficacy of ablating different types of fibroids, classified b...

journal_title：Scientific reports

authors： Zhao WP,Zhang J,Han ZY,Yao JP,Zhou X,Liang P

更新日期：2017-09-07 00:00:00

abstract：:The neural representation of auditory duration remains unknown. Here, we used electroencephalogram (EEG) recordings to investigate neural oscillations during the maintenance of auditory duration in working memory (WM). EEG analyses indicated that the auditory duration length was not associated with changes in the thet...

journal_title：Scientific reports

authors： Yu X,Chen Y,Qiu J,Li X,Huang X

更新日期：2017-07-18 00:00:00

abstract：:Gene selection is an attractive and important task in cancer survival analysis. Most existing supervised learning methods can only use the labeled biological data, while the censored data (weakly labeled data) far more than the labeled data are ignored in model building. Trying to utilize such information in the censo...

journal_title：Scientific reports

authors： Chai H,Li ZN,Meng DY,Xia LY,Liang Y

更新日期：2017-10-12 00:00:00

abstract：:This study tested the hypothesis that acquired epileptogenesis is accompanied by DNA methylation changes independent of etiology. We investigated DNA methylation and gene expression in the hippocampal CA3/dentate gyrus fields at 3 months following epileptogenic injury in three experimental models of epilepsy: focal am...

journal_title：Scientific reports

authors： Dębski KJ,Pitkanen A,Puhakka N,Bot AM,Khurana I,Harikrishnan KN,Ziemann M,Kaspi A,El-Osta A,Lukasiuk K,Kobow K

更新日期：2016-05-09 00:00:00

abstract：:Atomic Fermi gases have been an ideal platform for simulating conventional and engineering exotic physical systems owing to their multiple tunable control parameters. Here we investigate the effects of mixed dimensionality on the superfluid and pairing phenomena of a two-component ultracold atomic Fermi gas with a sho...

journal_title：Scientific reports

authors： Zhang L,Che Y,Wang J,Chen Q

更新日期：2017-10-11 00:00:00