Importance of whole-body imaging with complete coverage of hands and feet in alveolar rhabdomyosarcoma staging.

Abstract:

BACKGROUND:Alveolar rhabdomyosarcoma commonly arises in the extremities and is characterized by aggressive biology and high frequency of metastases. Whole-body imaging is increasingly employed in pediatric oncology but not recommended as standard in the staging of soft-tissue sarcomas. OBJECTIVE:After observing patients with a large symptomatic alveolar rhabdomyosarcoma lesion and a smaller silent lesion in the more distal part of an extremity we sought to estimate the frequency of this constellation. MATERIALS AND METHODS:We retrospectively evaluated the data of prospectively registered paediatric patients (age <21 years) with alveolar rhabdomyosarcoma in the SoTiSaR (Soft Tissue Sarcoma Registry) of the Cooperative Weichteilsarkom Studiengruppe (CWS) 09/2011-04/2015 with regard to whole-body imaging. RESULTS:Seventy-five patients were eligible. Images of 57 patients had been submitted for reference consultation, including 80 whole-body examinations in 36 patients. Among them were 5 patients (14%, 95% confidence interval 3-25%) who had been diagnosed because of a symptomatic lesion while an additional silent lesion in the distal part of an extremity had remained unnoticed and had only been detected by later whole-body imaging. It is noteworthy that in 42 (53%) of all 80 whole-body examinations, the hands and feet had been only partially covered or completely excluded. CONCLUSION:In alveolar rhabdomyosarcoma silent lesions can be overlooked when the distal parts of the limbs are not thoroughly examined and not completely covered by imaging. Missing them influences treatment decisions and prognosis. Our results should be considered when evaluating the potential role of whole-body imaging in rhabdomyosarcoma.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Scheer M,Dantonello T,Brossart P,Dilloo D,Schweigerer L,Feuchtgruber S,Sparber-Sauer M,Vokuhl C,Bielack SS,Klingebiel T,Koscielniak E,von Kalle T,Cooperative Weichteilsarkom Studiengruppe (CWS).

doi

10.1007/s00247-017-4066-8

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

648-657

issue

5

eissn

0301-0449

issn

1432-1998

pii

10.1007/s00247-017-4066-8

journal_volume

48

pub_type

杂志文章
  • Mesomelic dysplasia of the upper extremities associated with other abnormalities: a new syndrome?

    abstract::A 3-year-old Algerian boy with unusual facies, mesomelic dysplasia of the upper extremities, meta-epiphyseal changes in the lower extremities and skin dimples is reported. The authors are not able to classify the child's syndrome nosologically. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02012398

    authors: Kozlowski K,Bacha L,Brachimi L,Massen R

    更新日期:1993-01-01 00:00:00

  • Characteristic calcaneal ossification: an additional early radiographic finding in infants with fibrodysplasia ossificans progressiva.

    abstract:BACKGROUND:We have clinically encountered children with fibrodysplasia ossificans progressiva who had abnormal calcaneal ossification. OBJECTIVE:To evaluate whether calcaneal ossification variants are significant radiographic findings in children with fibrodysplasia ossificans progressiva. MATERIALS AND METHODS:Later...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-016-3662-3

    authors: Hasegawa S,Victoria T,Kayserili H,Zackai E,Nishimura G,Haga N,Nakashima Y,Miyazaki O,Kitoh H

    更新日期:2016-10-01 00:00:00

  • Radiological abnormalities associated with anomalies of the ninth chromosome.

    abstract::The clinical and radiological features of Trisomy of the short arm of the ninth chromosome and of the Nail Patella Syndrome, both of which conditions are related to abnormalities of the ninth chromosome, are compared. Dislocation of the head of radius is seen in both conditions, as is a diminished patello condylar rat...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF00975540

    authors: Pilling DW,Levick RK

    更新日期:1978-02-28 00:00:00

  • Ultrasonography in developmental dysplasia of the hip: what have we learned?

    abstract::Developmental dysplasia of the hip (DDH) is an important but poorly defined entity, the natural history of which is incompletely understood. The term encompasses a disease spectrum ranging from a stable hip with a mildly dysplastic acetabulum to complete hip dislocation. Much controversy surrounds the diagnosis, imagi...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00247-012-2429-8

    authors: Bracken J,Ditchfield M

    更新日期:2012-12-01 00:00:00

  • Laryngeal ultrasonography in infants and children: pathological findings.

    abstract::In a previous paper, the normal sonographic anatomy of the larynx has been described. The pathological findings of this method, its advantages and its drawbacks are now discussed and compared to endoscopy and plain films. It appears to be a very interesting method for functional disorders and space-occupying lesions. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02011037

    authors: Garel C,Hassan M,Legrand I,Elmaleh M,Narcy P

    更新日期:1991-01-01 00:00:00

  • Inherited protein-C deficiency, factor V G 1691 A and FV A 4070 G mutations in a child with internal cerebral venous thrombosis.

    abstract::Common systemic disorders that cause cerebral venous thrombosis (CVT) in children include dehydration, trauma, infection and haematological diseases. No cause for CVT is identified in one quarter of all cases. We report a child with thalamic infarcts due to internal CVT who had congenital heterozygous protein-C defici...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470050776

    authors: Sipahi T,Uner C,Yildiz YT,Akar N

    更新日期:2000-06-01 00:00:00

  • Is there a role for magnetic resonance imaging in the evaluation of non-traumatic intraparenchymal haemorrhage in children?

    abstract:BACKGROUND:In contrast to adults, intraparenchymal haemorrhage (IPH) is at least as common as ischaemic stroke in children. There is often uncertainty about the most appropriate modality for imaging in the acute stage. OBJECTIVE:To examine the diagnostic value of MRI and MR angiography (MRA) in the detection of underl...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-006-0236-9

    authors: Liu AC,Segaren N,Cox TS,Hayward RD,Chong WK,Ganesan V,Saunders DE

    更新日期:2006-09-01 00:00:00

  • Doxycycline sclerotherapy in children with lymphatic malformations: outcomes, complications and clinical efficacy.

    abstract:BACKGROUND:Lymphatic malformations (LMs) are congenital lesions of the lymphatic system and consist of lymphatic channels and cystic spaces of varying sizes. Recent evidence has shown that LMs respond well to intralesional sclerotherapy. OBJECTIVE:The purpose of this retrospective study is to evaluate the outcome and ...

    journal_title:Pediatric radiology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00247-012-2406-2

    authors: Shergill A,John P,Amaral JG

    更新日期:2012-09-01 00:00:00

  • Primary idiopathic chylopericardium.

    abstract::Primary idiopathic chylopericardium is rare and represents a fraction of all pericardial effusions in the pediatric population. Most cases of chylopericardium occur as a complication of cardiac surgery or after trauma. They may also be caused by tuberculosis, neoplasm, or congenital lymphangiomatosis. Primary idiopath...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-003-0885-x

    authors: Ossiani MH,McCauley RG,Patel HT

    更新日期:2003-05-01 00:00:00

  • European overview of current practice of fetal imaging by pediatric radiologists: a new task force is launched.

    abstract::A new task force dedicated to prenatal imaging was created in 2018 by the European Society of Pediatric Radiology. In order to establish a network of European prenatal imaging practice, we sent a questionnaire to radiologists practicing prenatal imaging in Europe. The questions were related to the type of institution,...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-020-04710-4

    authors: Cassart M,Garel C

    更新日期:2020-11-01 00:00:00

  • A proposed radiological classification of childhood intra-thoracic tuberculosis.

    abstract::One of the obstacles in discussing childhood tuberculosis (TB) is the lack of standard descriptive terminology to classify the diverse spectrum of disease. Accurate disease classification is important, because the correct identification of the specific disease entity has definite prognostic significance. Accurate clas...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-004-1238-0

    authors: Marais BJ,Gie RP,Schaaf HS,Starke JR,Hesseling AC,Donald PR,Beyers N

    更新日期:2004-11-01 00:00:00

  • Cystic fibrosis lung disease: genetic influences, microbial interactions, and radiological assessment.

    abstract::Cystic fibrosis (CF) is a multiorgan disease caused by mutation of the CF transmembrane conductance regulator (CFTR) gene. Obstructive lung disease is the predominant cause of morbidity and mortality; thus, most efforts to improve outcomes are directed toward slowing or halting lung-disease progression. Current therap...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00247-005-1445-3

    authors: Moskowitz SM,Gibson RL,Effmann EL

    更新日期:2005-08-01 00:00:00

  • CT localization of an aldosteronoma in a 10-year-old boy.

    abstract::Primary aldosteronism in children under 16 years of age is usually due to adrenal hyperplasia. We could find only seven cases in the literature where it was caused by a solitary adrenal adenoma; all but one were female. We describe the case of a 10-year-old Caucasian boy in whom a unilateral adrenal adenoma was demons...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02387519

    authors: Filiatrault D,Perreault G,Laberge JM,Ducharme JC

    更新日期:1986-01-01 00:00:00

  • Feuerstein and Mims syndrome with resistant rickets.

    abstract::A case of Feuerstein-Mims syndrome (naevus sebaceous, convulsions and mental retardation) is described in association with vitamin D resistant reckets. ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF00975318

    authors: Moorjani R,Shaw DG

    更新日期:1976-12-15 00:00:00

  • Diffusion-weighted MRI of middle cerebral artery stroke in a newborn.

    abstract::Diffusion-weighted MRI of the brain is becoming clinically available as a tool to investigate cerebral ischaemia. We report a newborn girl presenting with seizures in whom diffusion-weighted MRI showed a large hyperintensity in the area perfused by the left middle cerebral artery. Short-term neurological follow-up bef...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470100442

    authors: Lövblad KO,Ruoss K,Guzman R,Schroth G,Fusch C

    更新日期:2001-05-01 00:00:00

  • Normal size left ventricle on antenatal scan in lethal hypoplastic left heart syndrome.

    abstract::We present a case of lethal hypoplastic left heart syndrome missed at routine 20-week antenatal ultrasound examination because the left ventricle was of normal size on the standard four-chamber cardiac view. Hypoplastic left heart syndrome includes a spectrum of cardiac malformations. This case illustrates the difficu...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02026682

    authors: Anderson NG,Brown J

    更新日期:1991-01-01 00:00:00

  • Fundamentals of transorbital sonographic evaluation of optic nerve sheath expansion under intracranial hypertension II. Patient study.

    abstract::Up to now, the presence of elevated intracranial pressure (ICP) in acute neurological disorders is suspected by clinical and neuroimaging findings, but its verification depends on invasive techniques. Based on our experimental findings of rapid dilatation of human optic nerve sheaths (ONS), we investigated whether thi...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF01383384

    authors: Helmke K,Hansen HC

    更新日期:1996-10-01 00:00:00

  • Size of the intracranial optic nerve and optic tract in neonates at term-equivalent age at magnetic resonance imaging.

    abstract:BACKGROUND:The expected MRI-based dimensions of the intracranial optic nerve and optic tract in neonates are unknown. OBJECTIVE:To evaluate the sizes of the intracranial optic nerve and optic tract in neonates at term-equivalent age using MRI. MATERIALS AND METHODS:We retrospectively analyzed brain MRI examinations i...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-015-3495-5

    authors: Oyama J,Mori K,Imamura M,Mizushima Y,Tateishi U

    更新日期:2016-04-01 00:00:00

  • Normal values of the resistivity index of the pericallosal artery with and without compression of the anterior fontanelle.

    abstract:BACKGROUND:Resistivity index (RI) of the pericallosal artery as is commonly measured during head ultrasound (US) examination in neonates. Some studies have shown that RI measured with gentle compression of the fontanelle provides additional information in cases of neonatal brain anomalies. OBJECTIVE:The purpose of thi...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-019-04347-y

    authors: Elmfors AF,Sandgren T,Ford K,Rosenberg J,Ringertz H,Barth RA,Rubesova E

    更新日期:2019-05-01 00:00:00

  • Childhood idiopathic chondrolysis of the hip: MRI features.

    abstract:BACKGROUND:Childhood idiopathic chondrolysis of the hip (ICH) causes progressive destruction of the articular cartilage of the hip joint with associated bone remodelling. The MRI features of this disease have not previously been described. OBJECTIVE:To document the MRI features of childhood ICH and determine which fea...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-002-0853-x

    authors: Johnson K,Haigh SF,Ehtisham S,Ryder C,Gardner-Medwin J

    更新日期:2003-03-01 00:00:00

  • Artificial intelligence research within reach: an object detection model to identify rickets on pediatric wrist radiographs.

    abstract:BACKGROUND:Artificial intelligence models have been successful in analyzing ordinary photographic images. One type of artificial intelligence model is object detection, where a labeled bounding box is drawn around an area of interest. Object detection can be applied to medical imaging tasks. OBJECTIVE:To demonstrate o...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-020-04895-8

    authors: Meda KC,Milla SS,Rostad BS

    更新日期:2021-01-05 00:00:00

  • Unexpected MRI findings in clinically suspected Legg-Calvé-Perthes disease.

    abstract:BACKGROUND:In the setting of clinically suspected Legg-Calvé-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis. OBJECTIVE:To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP di...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-010-1841-1

    authors: Lobert PF,Dillman JR,Strouse PJ,Hernandez RJ

    更新日期:2011-03-01 00:00:00

  • Gallbladder contraction in biliary atresia: a pitfall of ultrasound diagnosis.

    abstract::In 3 (9 %) of 34 children with biliary atresia, US revealed gallbladder contraction following an oral feed, given on admission, but not with subsequent feeds. Surgery revealed a Kasai type IIIa biliary atresia with a patent communication between the gallbladder and duodenum. We propose that the bile ducts may initiall...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470050380

    authors: Ikeda S,Sera Y,Ohshiro H,Uchino S,Akizuki M,Kondo Y

    更新日期:1998-06-01 00:00:00

  • Atypical teratoid/rhabdoid tumor of the optic nerve.

    abstract::We report a rare case of atypical teratoid/rhabdoid tumor that presented with imaging findings similar to those of optic pathway glioma. The diagnosis of atypical teratoid/rhabdoid tumor was determined following surgical resection of the tumor by collective histologic and immunohistochemical staining, and cytogenetic ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-008-0923-9

    authors: Verma A,Morriss C

    更新日期:2008-10-01 00:00:00

  • Non-accidental injury: confusion with temporary brittle bone disease and mild osteogenesis imperfecta.

    abstract::Accurate diagnosis of non-accidental injury (NAI) can be reached in the majority of cases by careful appraisal of the social and family history, combined with painstaking clinical roentgenographic and other imaging evaluations. Careful review of the scientific literature clearly indicates that collagen analysis to exc...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s002470050079

    authors: Ablin DS,Sane SM

    更新日期:1997-02-01 00:00:00

  • Thoracic imaging of coronavirus disease 2019 (COVID-19) in children: a series of 91 cases.

    abstract:BACKGROUND:Pulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic. OBJECTIVE:To collect paediatric COVID-19 cases worldwide and to summarize both clinical and imaging findings in children who tested positive on poly...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00247-020-04747-5

    authors: Caro-Dominguez P,Shelmerdine SC,Toso S,Secinaro A,Toma P,Damasio MB,Navallas M,Riaza-Martin L,Gomez-Pastrana D,Ghadimi Mahani M,Desoky SM,Ugas Charcape CF,Almanza-Aranda J,Ucar ME,Lovrenski J,Gorkem SB,Alexopoulou E,Cie

    更新日期:2020-09-01 00:00:00

  • Problems associated with digital luminescence radiography in the neonate and young infant. Problems with digital radiography.

    abstract::An evaluation of the Siemens Digiscan has been undertaken to determine whether digital luminescence radiography (DLR) could replace conventional radiography in the examination of the neonate and young infant. Whilst the overall image quality of the digital radiograph was consistently higher than for conventional radio...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/BF02011600

    authors: Arthur RJ,Pease JN

    更新日期:1992-01-01 00:00:00

  • Heterotopic gastric mucosa involving the gallbladder and biliary tree.

    abstract::A case of heterotopic gastric mucosa in the common bile duct, cystic duct and gallbladder is reported in a 3-year-old girl with abdominal pain and jaundice. Abdominal US and CT showed dilatation of the biliary tree and a well-defined mass in the common bile duct that narrowed its lumen. The gallbladder was contracted ...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s00247-002-0718-3

    authors: Madrid C,Berrocal T,Gorospe L,Prieto C,Gámez M

    更新日期:2003-02-01 00:00:00

  • Primary chylous vaginal discharge in a 9-year-old girl: CT-lymphangiogram and MR appearance.

    abstract::Chylous reflux is a manifestation of primary or secondary lymphatic obstruction. Primary lymphatic obstruction is defined as lymphangiectasia and incompetency of lymphatic valves without an underlying cause. Lymphangiectasia resulting from trauma, neoplasm, irradiation, or inflammation characterizes secondary lymphati...

    journal_title:Pediatric radiology

    pub_type: 杂志文章

    doi:10.1007/s002470050219

    authors: Shahlaee AH,Burton EM,Sabio H,Plouffe L Jr,Teeslink R

    更新日期:1997-09-01 00:00:00

  • Management of auto exposure control during pediatric computed tomography.

    abstract::Automatic exposure control (AEC) is particularly well-suited for pediatric CT scanning. However the importance of the localizer scan portion of exams that relies on AEC is frequently underestimated. This paper explains in detail several crucial aspects of the localizer and their effect on the subsequent cross-sectiona...

    journal_title:Pediatric radiology

    pub_type: 杂志文章,评审

    doi:10.1007/s00247-014-3140-8

    authors: Cody DD

    更新日期:2014-10-01 00:00:00