Abstract:
:The nature of the Fc receptors for IgG subclasses displayed on the epithelium of the small intestine in neonatal rats was examined by comparing results gained from 125I-IgG binding studies using isolated enterocyte brush borders, and from experiments where in vivo transmission from the gut to the bloodstream was quantified for each subclass. These measurements were made in two strains of rat, Cob Wistar and CB Hooded Nu/+. Subclasses of IgG were transported from gut to blood in different amounts, and the in vitro binding also varied according to isotype. Comparison of the results between rat strains and between isotypes suggested that at least two IgG Fc receptors are present on the enterocytes of the young rat.
journal_name
Immunologyjournal_title
Immunologyauthors
Peppard JV,Jackson LE,Mackenzie NMsubject
Has Abstractpub_date
1985-09-01 00:00:00pages
51-5issue
1eissn
0019-2805issn
1365-2567journal_volume
56pub_type
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