Abstract:
BACKGROUND/AIMS:Scoliosis is common in patients with Chiari malformation-I (CM-I). This study examined the change in scoliosis severity after posterior fossa decompression (PFD) for CM-I. METHODS:We conducted a retrospective review at a single tertiary center for children undergoing PFD with untreated scoliosis, and identified 17 patients with complete follow-up data and imaging. RESULTS:Overall, scoliosis improved in 7 (41.2%) patients, worsened in 9 (52.9%), and remained unchanged in 1 (5.9%) after PFD (mean follow-up of 7.8 ± 4.1 months). We found that 3 of the 8 (38%) children with early-onset scoliosis eventually needed scoliosis corrective surgery, which was needed in 7 of the 9 (78%) patients with adolescent-onset scoliosis. In addition, only 1 patient (17%) with a preoperative scoliosis curve <35 degrees and 9 patients (82%) with a curve ≥35 degrees required surgery for scoliosis correction despite PFD (p = 0.018). CONCLUSION:In certain patients, PFD for CM-I may lead to improvement or stabilization of scoliosis.
journal_name
Pediatr Neurosurgjournal_title
Pediatric neurosurgeryauthors
Chotai S,Basem J,Gannon S,Dewan M,Shannon CN,Wellons JC,Bonfield CMdoi
10.1159/000485254subject
Has Abstractpub_date
2018-01-01 00:00:00pages
108-115issue
2eissn
1016-2291issn
1423-0305pii
000485254journal_volume
53pub_type
杂志文章abstract::A three-year old girl who initially presented at 16 months with epistaxis from an anterior skull base vascular anomaly returned with near-fatal epistaxis despite embolization of the internal maxillary artery at the time of initial presentation. Repeat angiography demonstrated blood supply to the vascular lesion coming...
journal_title:Pediatric neurosurgery
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abstract::Diffuse pontine tumors are highly lethal and conventional therapy with irradiation provides long-term survival to a very small proportion of the patients. We have reported promising results using high-dose chemotherapy with autologous stem cell rescue in patients with recurrent high-grade astrocytomas in other anatomi...
journal_title:Pediatric neurosurgery
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pub_type: 杂志文章,评审
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更新日期:2006-01-01 00:00:00
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journal_title:Pediatric neurosurgery
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更新日期:1995-01-01 00:00:00
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更新日期:2000-09-01 00:00:00
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更新日期:2018-01-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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