Genetic and molecular basis of the immune system in the brachiopod Lingula anatina.

Abstract:

:The extension of comparative immunology to non-model systems, such as mollusks and annelids, has revealed an unexpected diversity in the complement of immune receptors and effectors among evolutionary lineages. However, several lophotrochozoan phyla remain unexplored mainly due to the lack of genomic resources. The increasing accessibility of high-throughput sequencing technologies offers unique opportunities for extending genome-wide studies to non-model systems. As a result, the genome-based study of the immune system in brachiopods allows a better understanding of the alternative survival strategies developed by these immunologically neglected phyla. Here we present a detailed overview of the molecular components of the immune system identified in the genome of the brachiopod Lingula anatina. Our findings reveal conserved intracellular signaling pathways as well as unique strategies for pathogen detection and killing in brachiopods.

journal_name

Dev Comp Immunol

authors

Gerdol M,Luo YJ,Satoh N,Pallavicini A

doi

10.1016/j.dci.2017.12.021

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

7-30

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(17)30597-9

journal_volume

82

pub_type

杂志文章
  • Ontogeny of the thymus in a teleost fish, Cyprinus carpio L.: developing thymocytes in the epithelial microenvironment.

    abstract::A monoclonal antibody, WCL9, specific for membrane molecules of a thymocyte subpopulation was used to detect these cells in situ during the ontogeny of thymus. Cryo-sections revealed WCL9+ cells in the rudiment of the thymus (day 4 post fertilization); thereafter, the positive cells were observed exclusively in the co...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/s0145-305x(98)00053-6

    authors: Romano N,Taverne-Thiele AJ,Fanelli M,Baldassini MR,Abelli L,Mastrolia L,Van Muiswinkel WB,Rombout JH

    更新日期:1999-03-01 00:00:00

  • Plasmodium berghei induced priming in Anopheles albimanus independently of bacterial co-infection.

    abstract::Priming in invertebrates is the acquired capacity to better combat a pathogen due to a previous exposure to sub-lethal doses of the same organism. It is proposed to be functionally analogous to immune memory in vertebrates. Previous studies with Anopheles gambiae mosquitoes provide evidence that the inhibitory respons...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2015.05.004

    authors: Contreras-Garduño J,Rodríguez MC,Hernández-Martínez S,Martínez-Barnetche J,Alvarado-Delgado A,Izquierdo J,Herrera-Ortiz A,Moreno-García M,Velazquez-Meza ME,Valverde V,Argotte-Ramos R,Rodríguez MH,Lanz-Mendoza H

    更新日期:2015-10-01 00:00:00

  • The molecular evolution of the interleukin-1 family of cytokines; IL-18 in teleost fish.

    abstract::The cytokine network is an important homeostatic system with potent activities in immune surveillance, growth, developmental and repair processes. Although interleukin-1beta (IL-1beta) is considered a pivotal pro-inflammatory cytokine, merely focussing on its inflammatory role would be too narrow an approach. Elucidat...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.dci.2003.09.005

    authors: Huising MO,Stet RJ,Savelkoul HF,Verburg-van Kemenade BM

    更新日期:2004-05-03 00:00:00

  • Cellular recognition of foreign materials by Bombyx mori phagocytes: I. Immunocompetent cells.

    abstract::Though Bombyx mori larvae possess five types of hemocytes in the hemolymph, the granular cells play a key role as phagocytes and also participate in the early phase of encapsulation together with plasmacytes. In this sense, these two hemocytes are regarded as immunocompetent cells in B.mori. A granular cell can intern...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章,评审

    doi:

    authors: Wago H

    更新日期:1982-10-01 00:00:00

  • The roles of antimicrobial peptide, rip-thanatin, in the midgut of Riptortus pedestris.

    abstract::Recently, we have reported the structural determination of antimicrobial peptides (AMPs), such as riptocin, rip-defensin, and rip-thanatin, from Riptortus pedestris. However, the biological roles of AMPs in the host midgut remain elusive. Here, we compared the expression levels of AMP genes in apo-symbiotic insects wi...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2017.09.009

    authors: Park KE,Jang SH,Lee J,Lee SA,Kikuchi Y,Seo YS,Lee BL

    更新日期:2018-01-01 00:00:00

  • The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails.

    abstract::V(D)J recombination is a somatic gene rearrangement process that assembles antigen receptor genes from individual segments during lymphocyte development. The access of the RAG1/RAG2 recombinase to these gene segments is regulated at the level of chromatin modifications, in particular histone tail modifications. Trimet...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2008.03.012

    authors: Wilson DR,Norton DD,Fugmann SD

    更新日期:2008-01-01 00:00:00

  • The involvement of ecdysone and ecdysone receptor in regulating the expression of antimicrobial peptides in Chinese mitten crab, Eriocheir sinensis.

    abstract::The ecdysone, 20-hydroxyecdysone (20E) and ecdysone receptor (EcR), are regarded as the key regulators of development, metamorphosis, and growth in arthropods. In the present study, the role of 20E and EsEcR in regulating the expression of antimicrobial peptides (AMPs) was investigated in Chinese mitten crab, Eriochei...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2020.103757

    authors: Huang S,Yi Q,Lian X,Xu S,Yang C,Sun J,Wang L,Song L

    更新日期:2020-10-01 00:00:00

  • Age-related changes of naive and memory CD4 rat lymphocyte subsets in mucosal and systemic lymphoid organs.

    abstract::The purpose of this study was to investigate in rats, by double-label immunofluorescence and flow cytometric analysis, the age related changes in the CD4 subset of gut-associated lymphoid tissues and spleen. We found that the percentage of CD4+ T cells in Peyer's patches (PP) and spleen (SP) increased during the first...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/s0145-305x(97)00023-2

    authors: Fló J,Massouh E

    更新日期:1997-09-01 00:00:00

  • High doses of sodium ascorbate act as a prooxidant and protect gnotobiotic brine shrimp larvae (Artemia franciscana) against Vibrio harveyi infection coinciding with heat shock protein 70 activation.

    abstract::Ascorbate is an essential nutrient commonly regarded as an antioxidant. In this study, using axenic brine shrimp and pathogenic strain Vibrio harveyi as the host-pathogen model, we confirmed that pretreatment of sodium ascorbate (NaAs), at an optimum concentration, was a prooxidant by generation of hydrogen peroxide, ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2018.11.007

    authors: Han B,Kaur VI,Baruah K,Nguyen VD,Bossier P

    更新日期:2019-03-01 00:00:00

  • Exploring the relationships between amphibian (Xenopus laevis) myeloid cell subsets.

    abstract::The differentiation of distinct leukocyte subsets is governed by lineage-specific growth factors that elicit disparate expression of transcription factors and markers by the developing cell populations. For example, macrophages (Mφs) and granulocytes (Grns) arise from common granulocyte-macrophage progenitors in respo...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2020.103798

    authors: Yaparla A,Koubourli DV,Popovic M,Grayfer L

    更新日期:2020-12-01 00:00:00

  • Immune-relevant thrombocytes of common carp undergo parasite-induced nitric oxide-mediated apoptosis.

    abstract::Common carp thrombocytes account for 30-40% of peripheral blood leukocytes and are abundant in the healthy animals' spleen, the thrombopoietic organ. We show that, ex vivo, thrombocytes from healthy carp express a large number of immune-relevant genes, among which several cytokines and Toll-like receptors, clearly poi...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2015.02.008

    authors: Fink IR,Ribeiro CM,Forlenza M,Taverne-Thiele A,Rombout JH,Savelkoul HF,Wiegertjes GF

    更新日期:2015-06-01 00:00:00

  • Ontogeny of the rat thymus micro-environment: development of the interdigitating cell and macrophage populations.

    abstract::The ontogeny of the rat thymus micro-environment and in particular the development of the interdigitating cell (IDC) and macrophage (M phi) populations has been studied. At day 15 of fetal life the thymus consisted of an epithelial primordium in which some Thy-1 positive thymocytes were present around local capillarie...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(84)90077-6

    authors: Duijvestijn AM,Sminia T,Köhler YG,Janse EM,Hoefsmit EC

    更新日期:1984-10-01 00:00:00

  • Chemotaxis of nurse shark leukocytes.

    abstract::Studies were conducted to determine the ability of leukocytes from the nurse shark to migrate in an in vitro micropore filter chemotaxis assay and to determine optimal assay conditions and suitable attractants for such an assay. A migratory response was seen with several attractants: activated rat serum, activated sha...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(85)90113-2

    authors: Obenauf SD,Smith SH

    更新日期:1985-04-01 00:00:00

  • Spatial and temporal transcriptomic analyses reveal locust initiation of immune responses to Metarhizium acridum at the pre-penetration stage.

    abstract::Insect hemocyte and fat body tissues play critical functional roles in insect immunity. Little, however, is known concerning the dynamic responses of these tissues to fungal infection. Here, we report on a time course of locust hemocyte and fat body transcriptomic responses to infection by the acridid specific fungal ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2019.103524

    authors: Zhang W,Zheng X,Chen J,Keyhani NO,Cai K,Xia Y

    更新日期:2020-03-01 00:00:00

  • Transfection of crayfish hematopoietic tissue cells.

    abstract::Transfection is a powerful tool useful for studying gene function. Establishing transfection methods that enable highly efficient DNA uptake has become increasingly important. The crayfish hematopoietic tissue (Hpt) cell cultures have been proven to be suitable for studies on immunity and cell differentiation in crust...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2018.07.005

    authors: Shi H,Ruan L,Söderhäll I,Söderhäll K,Xu X

    更新日期:2018-11-01 00:00:00

  • Five subfamilies of β-defensin genes are present in salmonids: Evolutionary insights and expression analysis in Atlantic salmon Salmo salar.

    abstract::β-defensins (BD) are the largest family of vertebrate defensins with potent antimicrobial, chemotactic and immune-regulatory activities. Four BD genes (BD1-4) have been cloned previously in rainbow trout but none have been reported in other salmonids. In this study seven BD genes (BD1a-b, 2-4, 5a-b) are characterised ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2019.103560

    authors: Harte A,Tian G,Xu Q,Secombes CJ,Wang T

    更新日期:2020-03-01 00:00:00

  • Expression and functional characterization of interferon regulatory factors (irf2, irf7 and irf9) in the blunt snout bream (Megalobrama amblycephala).

    abstract::Interferon regulatory factors (irfs) are a family of genes that encode transcription factors with important roles in regulating the expression of Type I interferons (IFNs) and other genes associated with related pathways. irfs have multitudinous functions in growth, development and regulation of oncogenesis. In this s...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2016.09.014

    authors: Zhan FB,Liu H,Lai RF,Jakovlić I,Wang WM

    更新日期:2017-02-01 00:00:00

  • Identification, characterization and immunological response analysis of stimulator of interferon gene (STING) from grass carp Ctenopharyngodon idella.

    abstract::Stimulator of interferon gene (STING), an important adapter responsible for RLR pathway, plays a pivotal role in both viral RNA- and DNA-triggered induction of IFNs in mammals. To understand the roles of STING in piscine immune system, STING gene (CiSTING) was identified from grass carp (Ctenopharyngodon idella). The ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2014.03.001

    authors: Feng X,Yang C,Zhang Y,Peng L,Chen X,Rao Y,Gu T,Su J

    更新日期:2014-07-01 00:00:00

  • An alternative internal splicing site defines new Ikaros isoforms in Pleurodeles waltl.

    abstract::The Ikaros gene encodes a family of transcription factors which plays a crucial role in hematopoiesis. To improve our knowledge about the immune system of Pleurodeles waltl, we sequenced the cDNA coding for the Ik-1 isoform of that salamander and analyzed its tissue expression by semi-quantitative RT-PCR. Ikaros trans...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/s0145-305x(02)00014-9

    authors: Boudarra N,Frippiat C,Dournon C,Frippiat JP

    更新日期:2002-09-01 00:00:00

  • Serpin-15 from Bombyx mori inhibits prophenoloxidase activation and expression of antimicrobial peptides.

    abstract::Serine protease inhibitors (SPIs) play a key role in physiological responses by controlling protease activities. In this study, we studied the biochemical functions of serpin-15, an SPI, from Bombyx mori (Bmserpin-15). Recombinant Bmserpin-15 was expressed in Escherichia coli cells and used to raise rabbit anti-Bmserp...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2015.02.013

    authors: Liu D,Wang L,Yang L,Qian C,Wei G,Dai L,Li J,Zhu B,Liu C

    更新日期:2015-07-01 00:00:00

  • A developmental investigation of the liver, bone marrow and spleen of the stripe-faced dunnart (Sminthopsis macroura).

    abstract::The development of the liver, bone marrow and spleen have been investigated in the stripe-faced dunnart. At birth, the liver was undergoing haematopoiesis but the level declined rapidly and by day 50 after birth the liver was histologically mature. Both the bone marrow and spleen were non-haematopoietic at birth but i...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2003.08.004

    authors: Old JM,Selwood L,Deane EM

    更新日期:2004-04-01 00:00:00

  • Swine leukocyte antigen (SLA) diversity in Sinclair and Hanford swine.

    abstract::The swine leukocyte antigen (SLA) haplotype B is associated with increased penetrance of the tumor traits in Sinclair swine cutaneous melanoma (SSCM). We established a series of SinclairxHanford swine crosses to facilitate genetic mapping of the tumor-associated loci. In this study, the SLA diversity in the founding a...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2009.09.006

    authors: Ho CS,Martens GW,Amoss MS Jr,Gomez-Raya L,Beattie CW,Smith DM

    更新日期:2010-03-01 00:00:00

  • Melanization inhibition protein of Penaeus monodon acts as a negative regulator of the prophenoloxidase-activating system.

    abstract::Melanization mediated by the prophenoloxidase-activating system (proPO) is an important immune response in invertebrates. However, in addition to melanin, the proPO system produces reactive intermediates that are not only harmful to the invading microbes but also to the host cells. Thus, the proPO system must be tight...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2017.02.014

    authors: Noothuan N,Amparyup P,Tassanakajon A

    更新日期:2017-07-01 00:00:00

  • EcVig, a novel grouper immune-gene associated with antiviral activity against NNV infection.

    abstract::VHSV-induced genes (VIGs) were first identified in rainbow trout (Oncorhynchus mykiss) and subsequently isolated in a variety of fish. Recent studies have shown that most VIGs have immunological functions against pathogenic infections. However, most research has focused on Vig1, such that our present understanding of ...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2013.10.014

    authors: Yeh YC,Hsu YJ,Chen YM,Lin HY,Yang HL,Chen TY,Wang HC

    更新日期:2014-03-01 00:00:00

  • Antibody production in sharks and humans: a role for natural antibodies.

    abstract::Although gene segments specifying Igs of all vertebrates show clear homology, their arrangements differ markedly, thereby suggesting that the mechanisms for the generation of diversity and for the regulation of gene expression may be quite distinct. In the sandbar shark, light chain gene segments are distributed as ap...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/0145-305x(93)90014-h

    authors: Marchalonis JJ,Hohman VS,Thomas C,Schluter SF

    更新日期:1993-01-01 00:00:00

  • Lymphoid follicles of different phenotype appear in ileum during involution of the sheep ileal Peyer's patch.

    abstract::The ileal Peyer's patch (IPP) of young sheep is a site of diversification of the primary antibody repertoire and where involution takes place at young age. Tissue samples from the ileum were collected in 134 animals aged from 1 month to 6 years, and IPP follicle phenotypes were characterised. We describe a new type of...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2004.10.009

    authors: Lie KI,Aleksandersen M,Landsverk T

    更新日期:2005-01-01 00:00:00

  • Identification of a novel antimicrobial peptide from the sea star Patiria pectinifera.

    abstract::Antimicrobial peptides (AMPs) are components of innate immunity found in many forms of life. However, there have been no reports of AMPs in sea star (Phylum Echinodermata). Here we report the isolation and characterization of a novel antimicrobial peptide from the coelomic epithelium extract of the sea star Patiria pe...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2018.05.002

    authors: Kim CH,Go HJ,Oh HY,Park JB,Lee TK,Seo JK,Elphick MR,Park NG

    更新日期:2018-09-01 00:00:00

  • Bombyx mori nucleopolyhedrovirus downregulates transcription factor BmFoxO to elevate virus infection.

    abstract::Forkhead-box O (FoxO) is the primary transcriptional effector of the insulin-like signaling pathway that enhances gluconeogenesis through transcriptional activation of PEPCK and G6Pase in mammals. We have previously demonstrated the involvement of phosphoenolpyruvate carboxykinase (BmPEPCK-2) in antiviral immunity aga...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2020.103904

    authors: Kang X,Wang Y,Liang W,Tang X,Zhang Y,Wang L,Zhao P,Lu Z

    更新日期:2021-03-01 00:00:00

  • Comparative and phylogenetic analyses of three TIR domain-containing adaptors in metazoans: implications for evolution of TLR signaling pathways.

    abstract::Toll-like receptor adaptor molecule 1/2 (TICAM-1/2) and Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (TIRAP) play key roles in the Toll-like receptor (TLR) signaling pathways, which respond to viral and bacterial infections. These genes have been identified and studied in several vertebrates. Ho...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2011.02.009

    authors: Wu B,Xin B,Jin M,Wei T,Bai Z

    更新日期:2011-07-01 00:00:00

  • Characterization of the IRF2 proteins isolated from the deep-sea mussel Bathymodiolus platifrons and the shallow-water mussel Modiolus modiolus.

    abstract::Interferon regulatory factors (IRFs) are transcription factors that play important roles in immune defense, stress response, hematopoietic differentiation, and cell apoptosis. IRFs of invertebrate organisms and their functions remain largely unexplored. In the present study, for the first time new IRFs (BpIRF2 and MmI...

    journal_title:Developmental and comparative immunology

    pub_type: 杂志文章

    doi:10.1016/j.dci.2017.01.015

    authors: Huang B,Meng J,Yang M,Xu F,Li X,Li L,Zhang G

    更新日期:2017-06-01 00:00:00