Extracellular ATP elicits DORN1-mediated RBOHD phosphorylation to regulate stomatal aperture.

Abstract:

:In addition to acting as a cellular energy source, ATP can also act as a damage-associated molecular pattern in both animals and plants. Stomata are leaf pores that control gas exchange and, therefore, impact critical functions such as photosynthesis, drought tolerance, and also are the preferred entry point for pathogens. Here we show the addition of ATP leads to the rapid closure of leaf stomata and enhanced resistance to the bacterial pathogen Psuedomonas syringae. This response is mediated by ATP recognition by the receptor DORN1, followed by direct phosphorylation of the NADPH oxidase RBOHD, resulting in elevated production of reactive oxygen species and stomatal closure. Mutation of DORN1 phosphorylation sites on RBOHD eliminates the ability of ATP to induce stomatal closure. The data implicate purinergic signaling via DORN1 in the control of stomatal aperture with important implications for the control of plant photosynthesis, water homeostasis, pathogen resistance, and ultimately yield.

journal_name

Nat Commun

journal_title

Nature communications

authors

Chen D,Cao Y,Li H,Kim D,Ahsan N,Thelen J,Stacey G

doi

10.1038/s41467-017-02340-3

subject

Has Abstract

pub_date

2017-12-22 00:00:00

pages

2265

issue

1

issn

2041-1723

pii

10.1038/s41467-017-02340-3

journal_volume

8

pub_type

杂志文章
  • Ice sheets as a significant source of highly reactive nanoparticulate iron to the oceans.

    abstract::The Greenland and Antarctic Ice Sheets cover ~ 10% of global land surface, but are rarely considered as active components of the global iron cycle. The ocean waters around both ice sheets harbour highly productive coastal ecosystems, many of which are iron limited. Measurements of iron concentrations in subglacial run...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4929

    authors: Hawkings JR,Wadham JL,Tranter M,Raiswell R,Benning LG,Statham PJ,Tedstone A,Nienow P,Lee K,Telling J

    更新日期:2014-05-21 00:00:00

  • Tuning the interactions between chiral plasmonic films and living cells.

    abstract::Designing chiral materials to manipulate the biological activities of cells has been an important area not only in chemistry and material science, but also in cell biology and biomedicine. Here, we introduce monolayer plasmonic chiral Au nanoparticle (NP) films modified with L- or D-penicillamine (Pen) to be developed...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-017-02268-8

    authors: Zhao X,Xu L,Sun M,Ma W,Wu X,Xu C,Kuang H

    更新日期:2017-12-08 00:00:00

  • Extended anharmonic collapse of phonon dispersions in SnS and SnSe.

    abstract::The lattice dynamics and high-temperature structural transition in SnS and SnSe are investigated via inelastic neutron scattering, high-resolution Raman spectroscopy and anharmonic first-principles simulations. We uncover a spectacular, extreme softening and reconstruction of an entire manifold of low-energy acoustic ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18121-4

    authors: Lanigan-Atkins T,Yang S,Niedziela JL,Bansal D,May AF,Puretzky AA,Lin JYY,Pajerowski DM,Hong T,Chi S,Ehlers G,Delaire O

    更新日期:2020-09-04 00:00:00

  • An investigation of irreproducibility in maximum likelihood phylogenetic inference.

    abstract::Phylogenetic trees are essential for studying biology, but their reproducibility under identical parameter settings remains unexplored. Here, we find that 3515 (18.11%) IQ-TREE-inferred and 1813 (9.34%) RAxML-NG-inferred maximum likelihood (ML) gene trees are topologically irreproducible when executing two replicates ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-20005-6

    authors: Shen XX,Li Y,Hittinger CT,Chen XX,Rokas A

    更新日期:2020-11-30 00:00:00

  • Female song is widespread and ancestral in songbirds.

    abstract::Bird song has historically been considered an almost exclusively male trait, an observation fundamental to the formulation of Darwin's theory of sexual selection. Like other male ornaments, song is used by male songbirds to attract females and compete with rivals. Thus, bird song has become a textbook example of the p...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4379

    authors: Odom KJ,Hall ML,Riebel K,Omland KE,Langmore NE

    更新日期:2014-03-04 00:00:00

  • Noble gases confirm plume-related mantle degassing beneath Southern Africa.

    abstract::Southern Africa is characterised by unusually elevated topography and abnormal heat flow. This can be explained by thermal perturbation of the mantle, but the origin of this is unclear. Geophysics has not detected a thermal anomaly in the upper mantle and there is no geochemical evidence of an asthenosphere mantle con...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-12944-6

    authors: Gilfillan SMV,Györe D,Flude S,Johnson G,Bond CE,Hicks N,Lister R,Jones DG,Kremer Y,Haszeldine RS,Stuart FM

    更新日期:2019-11-05 00:00:00

  • Structural bases of IMiD selectivity that emerges by 5-hydroxythalidomide.

    abstract::Thalidomide and its derivatives exert not only therapeutic effects as immunomodulatory drugs (IMiDs) but also adverse effects such as teratogenicity, which are due in part to different C2H2 zinc-finger (ZF) transcription factors, IKZF1 (or IKZF3) and SALL4, respectively. Here, we report the structural bases for the SA...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18488-4

    authors: Furihata H,Yamanaka S,Honda T,Miyauchi Y,Asano A,Shibata N,Tanokura M,Sawasaki T,Miyakawa T

    更新日期:2020-09-14 00:00:00

  • Unscrambling fluorophore blinking for comprehensive cluster detection via photoactivated localization microscopy.

    abstract::Determining nanoscale protein distribution via Photoactivated Localization Microscopy (PALM) mandates precise knowledge of the applied fluorophore's blinking properties to counteract overcounting artifacts that distort the resulting biomolecular distributions. Here, we present a readily applicable methodology to deter...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18726-9

    authors: Platzer R,Rossboth BK,Schneider MC,Sevcsik E,Baumgart F,Stockinger H,Schütz GJ,Huppa JB,Brameshuber M

    更新日期:2020-10-05 00:00:00

  • Early-warning signals for Dansgaard-Oeschger events in a high-resolution ice core record.

    abstract::The Dansgaard-Oeschger (DO) events, as observed in oxygen isotope ratios from the North Greenland Ice Core Project (NGRIP) record, are an outstanding example of past abrupt climate transitions. Their physical cause remains debated, and previous research indicated that they are not preceded by classical early-warning s...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-04881-7

    authors: Boers N

    更新日期:2018-07-02 00:00:00

  • Multifunctional molecular modulators for perovskite solar cells with over 20% efficiency and high operational stability.

    abstract::Perovskite solar cells present one of the most prominent photovoltaic technologies, yet their stability, scalability, and engineering at the molecular level remain challenging. We demonstrate a concept of multifunctional molecular modulation of scalable and operationally stable perovskite solar cells that exhibit exce...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-06709-w

    authors: Bi D,Li X,Milić JV,Kubicki DJ,Pellet N,Luo J,LaGrange T,Mettraux P,Emsley L,Zakeeruddin SM,Grätzel M

    更新日期:2018-10-26 00:00:00

  • Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy.

    abstract::Genetic factors and mechanisms underlying food allergy are largely unknown. Due to heterogeneity of symptoms a reliable diagnosis is often difficult to make. Here, we report a genome-wide association study on food allergy diagnosed by oral food challenge in 497 cases and 2387 controls. We identify five loci at genome-...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-017-01220-0

    authors: Marenholz I,Grosche S,Kalb B,Rüschendorf F,Blümchen K,Schlags R,Harandi N,Price M,Hansen G,Seidenberg J,Röblitz H,Yürek S,Tschirner S,Hong X,Wang X,Homuth G,Schmidt CO,Nöthen MM,Hübner N,Niggemann B,Beyer K,Lee

    更新日期:2017-10-20 00:00:00

  • Expansion-contraction of photoresponsive artificial muscle regulated by host-guest interactions.

    abstract::The development of stimulus-responsive polymeric materials is of great importance, especially for the development of remotely manipulated materials not in direct contact with an actuator. Here we design a photoresponsive supramolecular actuator by integrating host-guest interactions and photoswitching ability in a hyd...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms2280

    authors: Takashima Y,Hatanaka S,Otsubo M,Nakahata M,Kakuta T,Hashidzume A,Yamaguchi H,Harada A

    更新日期:2012-01-01 00:00:00

  • Partially coherent radar unties range resolution from bandwidth limitations.

    abstract::It is widely believed that range resolution, the ability to distinguish between two closely situated targets, depends inversely on the bandwidth of the transmitted radar signal. Here we demonstrate a different type of ranging system, which possesses superior range resolution that is almost completely free of bandwidth...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-09380-x

    authors: Komissarov R,Kozlov V,Filonov D,Ginzburg P

    更新日期:2019-03-29 00:00:00

  • Cobalt-centred boron molecular drums with the highest coordination number in the CoB16- cluster.

    abstract::The electron deficiency and strong bonding capacity of boron have led to a vast variety of molecular structures in chemistry and materials science. Here we report the observation of highly symmetric cobalt-centered boron drum-like structures of CoB16(-), characterized by photoelectron spectroscopy and ab initio calcul...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms9654

    authors: Popov IA,Jian T,Lopez GV,Boldyrev AI,Wang LS

    更新日期:2015-10-12 00:00:00

  • Plasmonic tunnel junctions for single-molecule redox chemistry.

    abstract::Nanoparticles attached just above a flat metallic surface can trap optical fields in the nanoscale gap. This enables local spectroscopy of a few molecules within each coupled plasmonic hotspot, with near thousand-fold enhancement of the incident fields. As a result of non-radiative relaxation pathways, the plasmons in...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-017-00819-7

    authors: de Nijs B,Benz F,Barrow SJ,Sigle DO,Chikkaraddy R,Palma A,Carnegie C,Kamp M,Sundararaman R,Narang P,Scherman OA,Baumberg JJ

    更新日期:2017-10-20 00:00:00

  • ABL1 regulates spindle orientation in adherent cells and mammalian skin.

    abstract::Despite the growing evidence for the regulated spindle orientation in mammals, a systematic approach for identifying the responsible genes in mammalian cells has not been established. Here we perform a kinase-targeting RNAi screen in HeLa cells and identify ABL1 as a novel regulator of spindle orientation. Knockdown o...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms1634

    authors: Matsumura S,Hamasaki M,Yamamoto T,Ebisuya M,Sato M,Nishida E,Toyoshima F

    更新日期:2012-01-17 00:00:00

  • A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data.

    abstract::A common analysis of single-cell sequencing data includes clustering of cells and identifying differentially expressed genes (DEGs). How cell clusters are defined has important consequences for downstream analyses and the interpretation of results, but is often not straightforward. To address this difficulty, we prese...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-17900-3

    authors: Vandenbon A,Diez D

    更新日期:2020-08-28 00:00:00

  • Computational screen-out strategy for electrically pumped organic laser materials.

    abstract::Electrically pumped organic lasing is one of the most challenging issues in organic optoelectronics. We present a systematic theoretical investigation to screen out electrical pumping lasing molecules over a wide range of organic materials. With the electronic structure information obtained from time-dependent density...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-18144-x

    authors: Ou Q,Peng Q,Shuai Z

    更新日期:2020-09-08 00:00:00

  • Vanadium dioxide nanowire-based microthermometer for quantitative evaluation of electron beam heating.

    abstract::Temperature measurement is critical for many technological applications and scientific experiments, and different types of thermometers have been developed to detect temperature at macroscopic length scales. However, quantitative measurement of the temperature of nanostructures remains a challenge. Here, we show a new...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms5986

    authors: Guo H,Khan MI,Cheng C,Fan W,Dames C,Wu J,Minor AM

    更新日期:2014-10-13 00:00:00

  • Author Correction: REST regulates the cell cycle for cardiac development and regeneration.

    abstract::The original version of this Article contained an error in the spelling of the author Jianyun Yan, which was incorrectly given as Jiangyun Yan. This has now been corrected in both the PDF and HTML versions of the Article. ...

    journal_title:Nature communications

    pub_type: 杂志文章,已发布勘误

    doi:10.1038/s41467-017-02617-7

    authors: Zhang D,Wang Y,Lu P,Wang P,Yuan X,Yan J,Cai C,Chang CP,Zheng D,Wu B,Zhou B

    更新日期:2018-01-12 00:00:00

  • Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution.

    abstract::Biological tissues exhibit complex spatial heterogeneity that directs the functions of multicellular organisms. Quantifying protein expression is essential for elucidating processes within complex biological assemblies. Imaging mass spectrometry (IMS) is a powerful emerging tool for mapping the spatial distribution of...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-13858-z

    authors: Piehowski PD,Zhu Y,Bramer LM,Stratton KG,Zhao R,Orton DJ,Moore RJ,Yuan J,Mitchell HD,Gao Y,Webb-Robertson BM,Dey SK,Kelly RT,Burnum-Johnson KE

    更新日期:2020-01-07 00:00:00

  • Metamaterials with index ellipsoids at arbitrary k-points.

    abstract::Propagation behaviors of electromagnetic waves are governed by the equifrequency surface of the medium. Up to now, ordinary materials, including the medium exist in nature and the man-made metamaterials, always have an equifrequency surface (ellipsoid or hyperboloid) centered at zero k-point. Here we propose a new typ...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-018-04490-4

    authors: Chen WJ,Hou B,Zhang ZQ,Pendry JB,Chan CT

    更新日期:2018-05-25 00:00:00

  • Activation of G-protein-coupled receptors correlates with the formation of a continuous internal water pathway.

    abstract::Recent crystal structures of G-protein-coupled receptors (GPCRs) have revealed ordered internal water molecules, raising questions about the functional role of those waters for receptor activation that could not be answered by the static structures. Here, we used molecular dynamics simulations to monitor--at atomic an...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms5733

    authors: Yuan S,Filipek S,Palczewski K,Vogel H

    更新日期:2014-09-09 00:00:00

  • Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.

    abstract::Cancer evolution is fueled by epigenetic as well as genetic diversity. In chronic lymphocytic leukemia (CLL), intra-tumoral DNA methylation (DNAme) heterogeneity empowers evolution. Here, to comprehensively study the epigenetic dimension of cancer evolution, we integrate DNAme analysis with histone modification mappin...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-019-09645-5

    authors: Pastore A,Gaiti F,Lu SX,Brand RM,Kulm S,Chaligne R,Gu H,Huang KY,Stamenova EK,Béguelin W,Jiang Y,Schulman RC,Kim KT,Alonso A,Allan JN,Furman RR,Gnirke A,Wu CJ,Melnick AM,Meissner A,Bernstein BE,Abdel-Wahab O,L

    更新日期:2019-04-23 00:00:00

  • In vivo gastrointestinal drug-release monitoring through second near-infrared window fluorescent bioimaging with orally delivered microcarriers.

    abstract::Non-invasive monitoring of gastrointestinal drug release in vivo is extremely challenging because of the limited spatial resolution and long scanning time of existing bioimaging modalities, such as X-ray radiation and magnetic resonance. Here, we report a novel microcarrier that can retain drugs and withstand the hars...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms14702

    authors: Wang R,Zhou L,Wang W,Li X,Zhang F

    更新日期:2017-03-10 00:00:00

  • Supramolecular amplification of amyloid self-assembly by iodination.

    abstract::Amyloid supramolecular assemblies have found widespread exploitation as ordered nanomaterials in a range of applications from materials science to biotechnology. New strategies are, however, required for understanding and promoting mature fibril formation from simple monomer motifs through easy and scalable processes....

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms8574

    authors: Bertolani A,Pirrie L,Stefan L,Houbenov N,Haataja JS,Catalano L,Terraneo G,Giancane G,Valli L,Milani R,Ikkala O,Resnati G,Metrangolo P

    更新日期:2015-06-30 00:00:00

  • Overcoming evanescent field decay using 3D-tapered nanocavities for on-chip targeted molecular analysis.

    abstract::Enhancement of optical emission on plasmonic nanostructures is intrinsically limited by the distance between the emitter and nanostructure surface, owing to a tightly-confined and exponentially-decaying electromagnetic field. This fundamental limitation prevents efficient application of plasmonic fluorescence enhancem...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/s41467-020-16813-5

    authors: Kumar S,Park H,Cho H,Siddique RH,Narasimhan V,Yang D,Choo H

    更新日期:2020-06-10 00:00:00

  • Photonic Aharonov-Bohm effect in photon-phonon interactions.

    abstract::The Aharonov-Bohm effect is one of the most intriguing phenomena in both classical and quantum physics, and associates with a number of important and fundamental issues in quantum mechanics. The Aharonov-Bohm effects of charged particles have been experimentally demonstrated and found applications in various fields. R...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms4225

    authors: Li E,Eggleton BJ,Fang K,Fan S

    更新日期:2014-01-01 00:00:00

  • Persistent drying in the tropics linked to natural forcing.

    abstract::Approximately half of the world's population lives in the tropics, and future changes in the hydrological cycle will impact not just the freshwater supplies but also energy production in areas dependent upon hydroelectric power. It is vital that we understand the mechanisms/processes that affect tropical precipitation...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms8627

    authors: Winter A,Zanchettin D,Miller T,Kushnir Y,Black D,Lohmann G,Burnett A,Haug GH,Estrella-Martínez J,Breitenbach SF,Beaufort L,Rubino A,Cheng H

    更新日期:2015-07-14 00:00:00

  • Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres.

    abstract::Centromeres are specified epigenetically through the deposition of the centromere-specific histone H3 variant CENP-A. However, how additional epigenetic features are involved in centromere specification is unknown. Here, we find that histone H4 Lys5 and Lys12 acetylation (H4K5ac and H4K12ac) primarily occur within the...

    journal_title:Nature communications

    pub_type: 杂志文章

    doi:10.1038/ncomms13465

    authors: Shang WH,Hori T,Westhorpe FG,Godek KM,Toyoda A,Misu S,Monma N,Ikeo K,Carroll CW,Takami Y,Fujiyama A,Kimura H,Straight AF,Fukagawa T

    更新日期:2016-11-04 00:00:00