Shape analysis of the basioccipital bone in Pax7-deficient mice.

abstract：:The intrauterine environment is particularly vulnerable to environmental exposures. We previously established a mouse model that provided evidence for pregnancy complications and placental anti-angiogenesis in response to Aroclor 1254 (A-1254), a mixture of polychlorinated biphenyls (PCBs). Importantly, these effects ...

journal_title：Scientific reports

authors： Kalkunte S,Huang Z,Lippe E,Kumar S,Robertson LW,Sharma S

更新日期：2017-01-10 00:00:00

abstract：:Comparative genomic studies in primates have the potential to reveal the genetic and mechanistic basis for human specific traits. These studies may also help us better understand inter-species phenotypic differences that are clinically relevant. Unfortunately, the obvious limitation on sample collection and experiment...

journal_title：Scientific reports

authors： Pavlovic BJ,Blake LE,Roux J,Chavarria C,Gilad Y

更新日期：2018-10-17 00:00:00

abstract：:A high prevalence of obstructive sleep apnea (OSA) has been reported in Down syndrome (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality, posing a challenge for the management of OSA. We hypothesized that DS mice recapitulate craniofacial abnormalities and upper airway ob...

journal_title：Scientific reports

authors： Takahashi T,Sakai N,Iwasaki T,Doyle TC,Mobley WC,Nishino S

更新日期：2020-12-07 00:00:00

abstract：:Floating macrophytes, including water hyacinth (Eichhornia crassipes), are dominant invasive organisms in tropical aquatic systems, and they may play an important role in modifying the gas exchange between water and the atmosphere. However, these systems are underrepresented in global datasets of greenhouse gas (GHG) ...

journal_title：Scientific reports

authors： Attermeyer K,Flury S,Jayakumar R,Fiener P,Steger K,Arya V,Wilken F,van Geldern R,Premke K

更新日期：2016-02-05 00:00:00

abstract：:Light's polarisation contains information about its source and interactions, from distant stars to biological samples. Polarimeters can recover this information, but reliance on birefringent or rotating optical elements limits their wavelength range and stability. Here we present a static, single-shot polarimeter base...

journal_title：Scientific reports

authors： Hawley RD,Cork J,Radwell N,Franke-Arnold S

更新日期：2019-02-25 00:00:00

abstract：:Traffic-related air pollution is known to be associated with skin aging manifestations. We previously found that the use of fossil fuels was associated with skin aging, but no direct link between indoor air pollutants and skin aging manifestations has ever been shown. Here we directly measured the indoor PM2.5 exposur...

journal_title：Scientific reports

authors： Ding A,Yang Y,Zhao Z,Hüls A,Vierkötter A,Yuan Z,Cai J,Zhang J,Gao W,Li J,Zhang M,Matsui M,Krutmann J,Kan H,Schikowski T,Jin L,Wang S

更新日期：2017-11-10 00:00:00

abstract：:We describe the realization and characterization of a compact, autonomous fiber laser system that produces the optical frequencies required for laser cooling, trapping, manipulation, and detection of 87Rb atoms - a typical atomic species for emerging quantum technologies. This device, a customized laser system from th...

journal_title：Scientific reports

authors： Sabulsky DO,Junca J,Lefèvre G,Zou X,Bertoldi A,Battelier B,Prevedelli M,Stern G,Santoire J,Beaufils Q,Geiger R,Landragin A,Desruelle B,Bouyer P,Canuel B

更新日期：2020-02-24 00:00:00

abstract：:Dairy cows are often fed a high-concentrate (HC) diet to meet lactation demands; however, long-term concentrate feeding is unhealthy and decreases milk fat. Therefore, we investigated the effects of liver lipid metabolism on milk fat synthesis. Ten lactating Holstein cows were assigned randomly into HC and LC (low-con...

journal_title：Scientific reports

authors： Li L,Cao Y,Xie Z,Zhang Y

更新日期：2017-03-13 00:00:00

abstract：:Traumatic brain injury (TBI) is a leading cause of injury-related death worldwide, yet there are no approved neuroprotective therapies that improve neurological outcome post-injury. Transient opening of the blood-brain barrier following injury provides an opportunity for passive accumulation of intravenously administe...

journal_title：Scientific reports

authors： Miller HA,Magsam AW,Tarudji AW,Romanova S,Weber L,Gee CC,Madsen GL,Bronich TK,Kievit FM

更新日期：2019-11-06 00:00:00

abstract：:Heart failure after myocardial infarction (MI) depends on infarct size and adverse left ventricular (LV) remodelling, both influenced by the inflammatory response. Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is an inhibitory receptor of ITAM-dependent cell activation, present on almost all immune cell...

journal_title：Scientific reports

authors： Ellenbroek GHJM,de Haan JJ,van Klarenbosch BR,Brans MAD,van de Weg SM,Smeets MB,de Jong S,Arslan F,Timmers L,Goumans MTH,Hoefer IE,Doevendans PA,Pasterkamp G,Meyaard L,de Jager SCA

更新日期：2017-12-21 00:00:00

abstract：:Mycobacterium tuberculosis, the causative agent of tuberculosis, has surpassed HIV as the leading cause of death due to an infectious disease worldwide, being responsible for more than 1.5 million deaths in low-income countries. In response to a pandemic threat by drug resistant strains, the tuberculosis research comm...

journal_title：Scientific reports

authors： Soto R,Perez-Herran E,Rodriguez B,Duma BM,Cacho-Izquierdo M,Mendoza-Losana A,Lelievre J,Aguirre DB,Ballell L,Cox LR,Alderwick LJ,Besra GS

更新日期：2018-08-23 00:00:00

abstract：:Parametric analysis of Cerebellar Ataxia (CA) could be of immense value compared to its subjective clinical assessments. This study focuses on a comprehensive scheme for objective assessment of CA through the instrumented versions of 9 commonly used neurological tests in 5 domains- speech, upper limb, lower limb, gait...

journal_title：Scientific reports

authors： Kashyap B,Phan D,Pathirana PN,Horne M,Power L,Szmulewicz D

更新日期：2020-06-11 00:00:00

abstract：:Alzheimer's disease (AD) is a severe neurodegenerative disorder for which identification of differentially expressed genes is one way to find new therapeutic targets. Here, we conducted analysis to identify age-independent, AD-specific genes. We found that the MET, WIF1, and NPTX2 genes are downregulated in AD. WIF1 a...

journal_title：Scientific reports

authors： Liu H,Luo K,Luo D

更新日期：2018-02-09 00:00:00

abstract：:Neutron energy is directly correlated with the energy of the incident ions in experiments involving laser-driven nuclear reactions. Using high-energy incident ions reduces the energy concentration of the generated neutrons. A novel "laser-collider" method was used at the Shenguang II laser facility to produce monoener...

journal_title：Scientific reports

authors： Zhao JR,Zhang XP,Yuan DW,Li YT,Li DZ,Rhee YJ,Zhang Z,Li F,Zhu BJ,Li YF,Han B,Liu C,Ma Y,Li YF,Tao MZ,Li MH,Guo X,Huang XG,Fu SZ,Zhu JQ,Zhao G,Chen LM,Fu CB,Zhang J

更新日期：2016-06-02 00:00:00

abstract：:Worldwide biodiversity assessments have mainly focused on species richness but little is known about the diversity of species roles, i.e. functional diversity, while this is a key facet to understanding the consequences of global changes on the ecosystem services to human societies. Here, we report the world pattern o...

journal_title：Scientific reports

authors： Toussaint A,Charpin N,Brosse S,Villéger S

更新日期：2016-03-16 00:00:00

abstract：:Kalata B1 has been demonstrated to have bioactivity relating to membrane disruption. In this study, we conducted coarse-grained molecular dynamics simulations to gain further insight into kB1 bioactivity. The simulations were performed at various concentrations of kB1 to capture the overall progression of its activity...

journal_title：Scientific reports

authors： Nawae W,Hannongbua S,Ruengjitchatchawalya M

更新日期：2014-02-03 00:00:00

abstract：:In this work, lamellar MnFe2O4 was successfully planted on a wood surface through the association of hydrogen bonds via the one-pot hydrothermal method. Simultaneously, the fluoroalkylsilane (FAS-17) on the surface of the MnFe2O4 layer formed long-chain or network macromolecules through a poly-condensation process and...

journal_title：Scientific reports

authors： Wang H,Yao Q,Wang C,Fan B,Sun Q,Jin C,Xiong Y,Chen Y

更新日期：2016-10-17 00:00:00

abstract：:Three-dimensional anodic alumina templates (3D-AAO) are an astonishing framework with open highly ordered three-dimensional skeleton structures. Since these templates are architecturally different from conventional solids or porous templates, they teem with opportunities for engineering thermal properties. By establis...

journal_title：Scientific reports

authors： Abad B,Maiz J,Ruiz-Clavijo A,Caballero-Calero O,Martin-Gonzalez M

更新日期：2016-12-09 00:00:00

abstract：:A physically active lifestyle is associated with better health in body and mind, and it is urgent that supporting agents for such lifestyles be developed. In rodents, voluntary locomotor activity as an active physical behavior may be mediated by dopaminergic neurons (DNs). Thiamine phosphate esters can stimulate DNs, ...

journal_title：Scientific reports

authors： Saiki M,Matsui T,Soya M,Kashibe T,Shima T,Shimizu T,Naruto T,Kitayoshi T,Akimoto K,Ninomiya S,Soya H

更新日期：2018-07-11 00:00:00

abstract：:Trastuzumab combined with chemotherapy is standard of care for HER2 positive advanced gastro-esophageal cancers. The reported prevalence of HER2 discordance between primary tumors and corresponding metastases varies, hampering uniform patient selection for HER2 targeted therapy. This meta-analysis explores the influen...

journal_title：Scientific reports

authors： Creemers A,Ter Veer E,de Waal L,Lodder P,Hooijer GKJ,van Grieken NCT,Bijlsma MF,Meijer SL,van Oijen MGH,van Laarhoven HWM

更新日期：2017-06-09 00:00:00

abstract：:Chemotherapy (CTx)-induced premature ovarian failure (POF) in woman remains clinically irreversible. Amniotic fluid stem cells (AFSCs) have shown the potential to treat CTx-induced POF; however, the underlying mechanism is unclear. Here we demonstrate that AFSC-derived exosomes recapitulate the anti-apoptotic effect o...

journal_title：Scientific reports

authors： Xiao GY,Cheng CC,Chiang YS,Cheng WT,Liu IH,Wu SC

更新日期：2016-03-16 00:00:00

abstract：:The activation energy of the β → α/ω phase transformation increased monotonously with the application of a continuous heating process to a Ti-15Mo-2.7Nb-3Al-0.2Si alloy. Precipitation behaviour of the alloy aged at different temperatures were analysed with scanning electron microscopy, electron backscattered diffracti...

journal_title：Scientific reports

authors： Xu T,Zhang S,Liang S,Cui N,Cao L,Wan Y

更新日期：2019-11-26 00:00:00

abstract：:Identification of key regulators and regulatory pathways is an important step in the discovery of genes involved in cancer. Here, we propose a method to identify key regulators in prostate cancer (PCa) from a network constructed from gene expression datasets of PCa patients. Overexpressed genes were identified using B...

journal_title：Scientific reports

authors： Mangangcha IR,Malik MZ,Küçük Ö,Ali S,Singh RKB

更新日期：2019-11-11 00:00:00

abstract：:Centrioles are essential for forming cilia, flagella and centrosomes. Successful centriole assembly requires proteins of the SAS-6 family, which can form oligomeric ring structures with ninefold symmetry in vitro. While important progress has been made in understanding SAS-6 protein biophysics, the mechanisms enabling...

journal_title：Scientific reports

authors： Klein HC,Guichard P,Hamel V,Gönczy P,Schwarz US

更新日期：2016-06-08 00:00:00

abstract：:Vitamin D and parathyroid hormone (PTH) regulate mineral metabolism and are required to maintain calcium levels. Vitamin D deficiency is common, particularly during pregnancy, and has been associated with hypertensive disorders of pregnancy. We sought to determine whether maternal 25(OH)D, PTH and calcium concentratio...

journal_title：Scientific reports

authors： Santorelli G,Whitelaw D,Farrar D,West J,Lawlor DA

更新日期：2019-02-04 00:00:00

abstract：:A novel label-free electrochemiluminescence (ECL) immunosensor based on luminol functional-Au NPs@polypyrrole has been developed for the detection of carcinoembryonic antigen (CEA). In this work, polypyrrole prepared by chemical polymerization provided a large surface area to load amounts of gold nanoparticles (Au NPs...

journal_title：Scientific reports

authors： Zhu W,Wang Q,Ma H,Lv X,Wu D,Sun X,Du B,Wei Q

更新日期：2016-04-19 00:00:00

abstract：:Tissue fibrosis underlies the majority of human mortality to date with close to half of all reported deaths having a fibrotic etiology. The progression of fibrosis is very complex and reputed irreversible once established. Although some preventive options are being reported, therapeutic options are still scarce and in...

journal_title：Scientific reports

authors： Nono JK,Fu K,Mpotje T,Varrone G,Aziz NA,Mosala P,Hlaka L,Kamdem SD,Xu D,Spangenberg T,Brombacher F

更新日期：2020-06-30 00:00:00

abstract：:Karrikins (KAR) are a class of signal compounds, discovered in wildfire smoke, which affect seed germination. Currently, numerous studies have focused on the model plant Arabidopsis in the KAR research field, rather than on crops. Thus the regulatory mechanisms underlying KAR regulation of crop seed germination are la...

journal_title：Scientific reports

authors： Meng Y,Chen F,Shuai H,Luo X,Ding J,Tang S,Xu S,Liu J,Liu W,Du J,Liu J,Yang F,Sun X,Yong T,Wang X,Feng Y,Shu K,Yang W

更新日期：2016-02-23 00:00:00

abstract：:In this article we advance a cutting-edge methodology for the study of the dynamics of plant movements of nutation. Our approach, unlike customary kinematic analyses of shape, period, or amplitude, is based on three typical signatures of adaptively controlled processes and motions, as reported in the biological and be...

journal_title：Scientific reports

authors： Raja V,Silva PL,Holghoomi R,Calvo P

更新日期：2020-11-10 00:00:00

abstract：:Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified as the umami (savory) taste receptor. Amino acids and 5'-ribonucleotides are well known to be natural ligands for human...

journal_title：Scientific reports

authors： Toda Y,Nakagita T,Hirokawa T,Yamashita Y,Nakajima A,Narukawa M,Ishimaru Y,Uchida R,Misaka T

更新日期：2018-08-07 00:00:00