Extracellular Cyclic GMP Modulates Membrane Expression of The GluA1 and GluA2 Subunits of AMPA Receptor in Cerebellum: Molecular Mechanisms Involved.

abstract：:Antibiotics in feed select for resistant strains and is thus a threat to human health. In this study, the effect of a multi-strain probiotic and antibiotics on the growth and health of broilers was studied. Equal numbers of broilers received on a daily basis either a multi-strain probiotic or a combination of sulphadi...

journal_title：Scientific reports

authors： Neveling DP,van Emmenes L,Ahire JJ,Pieterse E,Smith C,Dicks LMT

更新日期：2017-10-16 00:00:00

abstract：:Peatlands perform important ecosystem functions, such as carbon storage and nutrient retention, which are affected, among other factors, by vegetation and peat decomposition. The availability of silicon (Si) in peatlands differs strongly, ranging from <1 to >25 mg L-1. Since decomposition of organic material was recen...

journal_title：Scientific reports

authors： Reithmaier GS,Knorr KH,Arnhold S,Planer-Friedrich B,Schaller J

更新日期：2017-08-18 00:00:00

abstract：:Nucleic acid amplification tests have become a common method for diagnosis of STIs due to their improved sensitivity over immunoassays and traditional culture-based methods. Isothermal nucleic acid amplification methods offer significant advantages over polymerase chain reaction (PCR) because they do not require sophi...

journal_title：Scientific reports

authors： Eboigbodin KE,Hoser MJ

更新日期：2016-02-03 00:00:00

abstract：:Arabidopsis VIRE2-INTERACTING PROTEIN2 (VIP2) was previously described as a protein with a NOT domain, and Arabidopsis vip2 mutants are recalcitrant to Agrobacterium-mediated root transformation. Here we show that VIP2 is a transcription regulator and the C-terminal NOT2 domain of VIP2 interacts with VirE2. Interestin...

journal_title：Scientific reports

authors： Raman V,Anand A,Vasudevan B,Morsy MR,Pant BD,Lee HK,Tang Y,Mysore KS

更新日期：2019-09-18 00:00:00

abstract：:Nitric oxide (NO), a vascular signaling molecule, is primarily produced by endothelial NO synthase. Recently, a functional endothelial NO synthase (eNOS) was described in red blood cells (RBC). The RBC-eNOS contributes to the intravascular NO pool and regulates physiological functions. However the regulatory mechanism...

journal_title：Scientific reports

authors： Nagarajan S,Raj RK,Saravanakumar V,Balaguru UM,Behera J,Rajendran VK,Shathya Y,Ali BM,Sumantran V,Chatterjee S

更新日期：2016-06-27 00:00:00

abstract：:It has been hypothesised that speed information, encoded by 'speed cells', is important for updating spatial representation in the hippocampus and entorhinal cortex to reflect ongoing self-movement during locomotion. However, systematic characterisation of speed representation is still lacking. In this study, we compa...

journal_title：Scientific reports

authors： Iwase M,Kitanishi T,Mizuseki K

更新日期：2020-01-29 00:00:00

abstract：:We study Coulomb interacting electrons confined in polygonal quantum rings. We focus on the interplay of localization at the polygon corners and Coulomb repulsion. Remarkably, the Coulomb repulsion allows the formation of in-gap states, i.e., corner-localized states of electron pairs or clusters shifted to energies th...

journal_title：Scientific reports

authors： Sitek A,Ţolea M,Niţă M,Serra L,Gudmundsson V,Manolescu A

更新日期：2017-01-10 00:00:00

abstract：:This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...

journal_title：Scientific reports

authors： Vakifahmetoglu C,Zeydanli D,Innocentini MD,Ribeiro FD,Lasso PR,Soraru GD

更新日期：2017-01-20 00:00:00

abstract：:Ultraviolet-B (UVB) radiation damages plants and decreases their growth and productivity. We previously demonstrated that UVB sensitivity varies widely among Asian rice (Oryza sativa L.) cultivars and that the activity of cyclobutane pyrimidine dimer (CPD) photolyase, which repairs UVB-induced CPDs, determines UVB sen...

journal_title：Scientific reports

authors： Mmbando GS,Teranishi M,Hidema J

更新日期：2020-02-21 00:00:00

abstract：:This study compared effects of five hypoxia-inducible factor (HIF) prolyl hydroxylases (PHD) inhibitors on PC12 cells and primary rat neurons following oxygen-glucose deprivation (OGD). At 100 µM, the PHD inhibitors did not cause cytotoxicity and apoptosis. MTT activity was only significantly reduced by FG4592 or Baye...

journal_title：Scientific reports

authors： Singh A,Wilson JW,Schofield CJ,Chen R

更新日期：2020-01-31 00:00:00

abstract：:Mutations in the Norrin (NDP) gene cause severe developmental blood vessel defects in the retina leading to congenital blindness. In the retina of Ndph-knockout mice only the superficial capillary network develops. Here, a detailed characterization of this mouse model at late stages of the disease using in vivo retina...

journal_title：Scientific reports

authors： Beck SC,Karlstetter M,Garcia Garrido M,Feng Y,Dannhausen K,Mühlfriedel R,Sothilingam V,Seebauer B,Berger W,Hammes HP,Seeliger MW,Langmann T

更新日期：2018-04-13 00:00:00

abstract：:Burgeoning availability of genome-wide association study (GWAS) results and national biobank data has led to growing interest in performing multi-trait genetic analyses. Numerous multi-trait GWAS methods that exploit either summary statistics or individual-level data have been developed, but their relative performance...

journal_title：Scientific reports

authors： Porter HF,O'Reilly PF

更新日期：2017-03-13 00:00:00

abstract：:Up to 30% of all breast cancer cases may be inherited and up to 85% of those may be due to segregation of susceptibility genes with low and moderate risk [odds ratios (OR) ≤ 3] for (mostly peri- and post-menopausal) breast cancer. The majority of low/moderate-risk genes, particularly those with minor allele frequencie...

journal_title：Scientific reports

authors： Moslehi R,Tsao HS,Zeinomar N,Stagnar C,Fitzpatrick S,Dzutsev A

更新日期：2020-12-04 00:00:00

abstract：:We report that misfolded cytosolic proteins can be cleared from mammalian cells by directing them to endoplasmic reticulum (ER). NAT1 R64W and Parkin R42P are naturally occurring misfolded variants of cytosolic enzymes that acetylate arylamines and ubiquitinate proteins, respectively. We demonstrate that proteasome in...

journal_title：Scientific reports

authors： Liu F,Koepp DM,Walters KJ

更新日期：2015-07-14 00:00:00

abstract：:In patients with type 1 diabetes mellitus (T1DM), glucose dynamics are influenced by insulin reactions, diet, lifestyle, etc., and characterized by instability and nonlinearity. With the objective of a dependable decision support system for T1DM self-management, we aim to model glucose dynamics using their nonlinear c...

journal_title：Scientific reports

authors： Frandes M,Timar B,Timar R,Lungeanu D

更新日期：2017-07-24 00:00:00

abstract：:Conditional gene expression systems that enable inducible and reversible transcriptional control are essential research tools and have broad applications in biomedicine and biotechnology. The reverse tetracycline transcriptional activator is a canonical system for engineered gene expression control that enables graded...

journal_title：Scientific reports

authors： Roney IJ,Rudner AD,Couture JF,Kærn M

更新日期：2016-06-21 00:00:00

abstract：:Plant height (PH) is a key factor in maize (Zea mays L.) yield, biomass, and plant architecture. We investigated the PH of diverse maize inbred lines (117 temperate lines, 135 tropical lines) at four growth stages using unmanned aerial vehicle high-throughput phenotypic platforms (UAV-HTPPs). We extracted PH data usin...

journal_title：Scientific reports

authors： Wang X,Zhang R,Song W,Han L,Liu X,Sun X,Luo M,Chen K,Zhang Y,Yang H,Yang G,Zhao Y,Zhao J

更新日期：2019-03-05 00:00:00

abstract：:The formation of OD (order-disorder) phases of the LPSO (long-period stacking ordered)-type in Mg-Al-RE (RE (rare earth) = Y, La, Ce, Nd, Sm, Dy, Ho, Er and Yb) ternary systems has been investigated for both as-solidified and annealed conditions. The OD phase is found to form in those systems with RE = Y, Nd, Sm, Dy, ...

journal_title：Scientific reports

authors： Kishida K,Yokobayashi H,Inui H

更新日期：2017-09-25 00:00:00

abstract：:Successful synthetic biology efforts rely on conceptual and experimental designs in combination with testing of multi-gene constructs. Despite recent progresses, several limitations still hinder the ability to flexibly assemble and collectively share different types of DNA segments. Here, we describe an advanced syste...

journal_title：Scientific reports

authors： De Paoli HC,Tuskan GA,Yang X

更新日期：2016-01-13 00:00:00

abstract：:Fruit firmness is an important market driven trait in sweet cherry (Prunus avium L.) where the desirable increase in fruit firmness is associated with landrace and bred cultivars. The aim of this work was to investigate the genetic basis of fruit firmness using plant materials that include wild cherry (syn. mazzard), ...

journal_title：Scientific reports

authors： Cai L,Quero-García J,Barreneche T,Dirlewanger E,Saski C,Iezzoni A

更新日期：2019-03-21 00:00:00

abstract：:Mesoporous silica nanoscale microsphere (MSNM), with a special morphology, high porosity, large pore volume and specific surface area, was successfully prepared and used as the matrix material of lauric acid (LA) to prepare a favorable shape-stabilized phase change material (LA/MSNM). The porous network structure of M...

journal_title：Scientific reports

authors： Zhang Z,Wang J,Tang X,Liu Y,Han Z,Chen Y

更新日期：2019-11-05 00:00:00

abstract：:Quorum-sensing (QS) systems exist universally in bacteria to regulate multiple biological functions. Klebsiella pneumoniae, an industrially important bacterium that produces bio-based chemicals such as 2,3-butanediol and acetoin, can secrete a furanosyl borate diester (AI-2) as the signalling molecule mediating a QS s...

journal_title：Scientific reports

authors： Sun S,Zhang H,Lu S,Lai C,Liu H,Zhu H

更新日期：2016-12-07 00:00:00

abstract：:Flux balance analysis is the only modelling approach that is capable of producing genome-wide predictions of gene essentiality that may aid to unveil metabolic liabilities in cancer. Nevertheless, a systemic validation of gene essentiality predictions by flux balance analysis is currently missing. Here, we critically ...

journal_title：Scientific reports

authors： Gatto F,Miess H,Schulze A,Nielsen J

更新日期：2015-06-04 00:00:00

abstract：:We employ nematic liquid crystals as the nonlinear medium to recover noisy images via stochastic resonance, in which nonlinear coupling allows signals to grow at the expense of noise. The process is theoretically analyzed and the cross-correlation is numerically calculated. It is found that the quality of output image...

journal_title：Scientific reports

authors： Feng X,Liu H,Huang N,Wang Z,Zhang Y

更新日期：2019-03-08 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia characterized by the formation of amyloid plaques (Aβ). Over the last decade, the important role of the innate immune system for the disease development has been established. Chronic activation of microglial cells creates a proinflammatory environment, which...

journal_title：Scientific reports

authors： Boza-Serrano A,Yang Y,Paulus A,Deierborg T

更新日期：2018-01-24 00:00:00

abstract：:Despite a long history, the clinical efficacy of cupping therapy is still under debate. This is likely due to the lack of direct evidence for the biological actions of cupping, since the short exposure of cells to vacuum condition rarely has affects cellular activity. In this study, the medicinal properties of a recen...

journal_title：Scientific reports

authors： Lee HY,Lee HJ,Kim GC,Choi JH,Hong JW

更新日期：2019-03-07 00:00:00

abstract：:In this study, we sought to enhance the cutting properties of the various blades by coating them with Zr- and Fe-based thin film metallic glasses (TFMGs) to a thickness of 234-255 nm via sputter deposition. In oil-repellency/sliding tests on kitchen blades, the sliding angle and friction forces were as follows: bare b...

journal_title：Scientific reports

authors： Chu JP,Diyatmika W,Tseng YJ,Liu YK,Liao WC,Chang SH,Chen MJ,Lee JW,Jang JSC

更新日期：2019-10-29 00:00:00

abstract：:Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to muscle hypertrophy or double-muscled (DM) phenotype in cattle, sheep, dog and human. However, there has not been reported significant muscle phenotypes in pigs in association with MSTN mutations. Pigs...

journal_title：Scientific reports

authors： Qian L,Tang M,Yang J,Wang Q,Cai C,Jiang S,Li H,Jiang K,Gao P,Ma D,Chen Y,An X,Li K,Cui W

更新日期：2015-09-24 00:00:00

abstract：:A long-standing debate regarding the configuration of Pangea during the Late Paleozoic has been going on among the paleomagnetic community concerning the validity of one of two significantly different Pangea reconstructions (Pangea A vs Pangea B) since the proposal of Pangea B. Although, Pangea B avoids any continenta...

journal_title：Scientific reports

authors： Tomezzoli RN,Tickyj H,Rapalini AE,Gallo LC,Cristallini EO,Arzadún G,Chemale F Jr

更新日期：2018-05-31 00:00:00

abstract：:A tool to predict peritonitis-associated treatment failure among peritoneal dialysis (PD) patients has not yet been established. We conducted a multicentre, retrospective cohort study among 1,025 PD patients between 2006 and 2016 in Thailand to develop and internally validate such a tool. Treatment failure was defined...

journal_title：Scientific reports

authors： Nochaiwong S,Ruengorn C,Koyratkoson K,Thavorn K,Awiphan R,Chaisai C,Phatthanasobhon S,Noppakun K,Suteeka Y,Panyathong S,Dandecha P,Chongruksut W,Nanta S,Thai Renal Outcomes Research (THOR) Investigators.

更新日期：2018-10-04 00:00:00