Generation of bioinspired structural colors via two-photon polymerization.

abstract：:The analysis of DNA methylation at CpG dinucleotides has become a major research focus due to its regulatory role in numerous biological processes, but the requisite need for assays which amplify bisulfite-converted DNA represents a major bottleneck due to the unique design constraints imposed on bisulfite-PCR primers...

journal_title：Scientific reports

authors： Lu J,Johnston A,Berichon P,Ru KL,Korbie D,Trau M

更新日期：2017-01-24 00:00:00

abstract：:The spread of multidrug-resistant Staphylococcus aureus strains, including methicillin-resistant S. aureus (MRSA), has shortened the useful life of anti-staphylococcal drugs enormously. Two approaches can be followed to address this problem: screening various sources for new leads for antibiotics or finding ways to di...

journal_title：Scientific reports

authors： Abreu AC,Coqueiro A,Sultan AR,Lemmens N,Kim HK,Verpoorte R,van Wamel WJB,Simões M,Choi YH

更新日期：2017-06-19 00:00:00

abstract：:Serotype-cross-reactive memory T cells responding to secondary dengue virus (DENV) infection are thought to contribute to disease. However, epitope-specific T cell responses have not been thoroughly compared between subjects with primary versus secondary DENV infection. We studied CD8(+) T cells specific for the HLA-A...

journal_title：Scientific reports

authors： Friberg H,Bashyam H,Toyosaki-Maeda T,Potts JA,Greenough T,Kalayanarooj S,Gibbons RV,Nisalak A,Srikiatkhachorn A,Green S,Stephens HA,Rothman AL,Mathew A

更新日期：2011-01-01 00:00:00

abstract：:Therapeutic strategies based on the principles of tissue engineering by self-assembly put forward the notion that functional regeneration can be achieved by utilising the inherent capacity of cells to create highly sophisticated supramolecular assemblies. However, in dilute ex vivo microenvironments, prolonged culture...

journal_title：Scientific reports

authors： Kumar P,Satyam A,Fan X,Collin E,Rochev Y,Rodriguez BJ,Gorelov A,Dillon S,Joshi L,Raghunath M,Pandit A,Zeugolis DI

更新日期：2015-03-04 00:00:00

abstract：:The occurrence of toxic metals in the aquatic environment is as caused by a variety of contaminations which makes difficulty in the concentration prediction. In this study, conventional methods of back-propagation neural network (BPNN) and nonlinear autoregressive network with exogenous inputs (NARX) were applied as b...

journal_title：Scientific reports

authors： Li P,Hua P,Gui D,Niu J,Pei P,Zhang J,Krebs P

更新日期：2020-08-10 00:00:00

abstract：:Hedgehog (Hh) signaling plays a broad role in the development of many organs including bone and teeth. It is noted that sustained Hh activity in osteoblasts negatively regulates postnatal development in mice. However, it remains unknown whether Hh signaling contributes to cementum formation. In this study, to define t...

journal_title：Scientific reports

authors： Choi H,Liu Y,Yang L,Cho ES

更新日期：2020-04-29 00:00:00

abstract：:Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac promoter. In this arti...

journal_title：Scientific reports

authors： Fulcrand G,Dages S,Zhi X,Chapagain P,Gerstman BS,Dunlap D,Leng F

更新日期：2016-01-14 00:00:00

abstract：:We investigated retinal structure and function in eyes with optic nerve hypoplasia (ONH). Twenty-nine eyes of 18 patients with ONH and 21 eyes of 21 control patients were analyzed. Spectral-domain optical coherence tomography (SD-OCT), full-field electroretinography (FF-ERG), and focal macular ERG (FM-ERG) were perfor...

journal_title：Scientific reports

authors： Katagiri S,Nishina S,Yokoi T,Mikami M,Nakayama Y,Tanaka M,Azuma N

更新日期：2017-02-16 00:00:00

abstract：:To comprehensively assess whether p75ECD in urine could be a candidate biomarker for ALS evaluation. Urine samples were collected from 101 ALS patients, 108 patients with other neurological disease (OND) and 97 healthy controls. 61 ALS patients were followed up with clinical data including ALSFRS-r every 6 to 12 month...

journal_title：Scientific reports

authors： Jia R,Shepheard S,Jin J,Hu F,Zhao X,Xue L,Xiang L,Qi H,Qu Q,Guo F,Rogers ML,Dang J

更新日期：2017-07-11 00:00:00

abstract：:Hepatocyte-specific HMGB1 deletion has been found to worsen the injury and inflammation in liver ischemia-reperfusion injury (IRI), highlighting a role for intracellular HMGB1 in cellular protection. Down-regulation of nuclear HMGB1 by small interfering RNA (siRNA) might not only decrease its injurious extracellular r...

journal_title：Scientific reports

authors： Zhao G,Fu C,Wang L,Zhu L,Yan Y,Xiang Y,Zheng F,Gong F,Chen S,Chen G

更新日期：2017-04-06 00:00:00

abstract：:The integrity of the corticospinal tract (CST) is significantly affected following basal ganglia haemorrhage. We aimed to assess the local features of CST and to effectively predict motor function by diffusion characteristics of CST in patients with motor injury following acute haemorrhage in the acute basal ganglia r...

journal_title：Scientific reports

authors： Li J,Wei XH,Liu YK,Chen LS,Zhu ZQ,Hou SY,Fang XK,Wang ZQ

更新日期：2020-10-01 00:00:00

abstract：:Sex steroids, such as estrogens and androgens, are important regulators of the humoral immune response. Studies in female mice have demonstrated that alteration of circulating estrogen concentration regulates antibody-mediated immunity. As males have normally little endogenous estrogen, we hypothesized that in males h...

journal_title：Scientific reports

authors： Aguilar-Pimentel JA,Cho YL,Gerlini R,Calzada-Wack J,Wimmer M,Mayer-Kuckuk P,Adler T,Schmidt-Weber CB,Busch DH,Fuchs H,Gailus-Durner V,Ollert M,Hrabě de Angelis M,Ohlsson C,Poutanen M,Teperino R,Strauss L

更新日期：2020-10-27 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep34617. ...

journal_title：Scientific reports

authors： Lee SH,Park JS,Byun JK,Jhun J,Jung K,Seo HB,Moon YM,Kim HY,Park SH,Cho ML

更新日期：2017-09-27 00:00:00

abstract：:Surfaces with reversible wettability have broad applications but remain challenging since the switching process is usually energy intensive and complex. In this paper, a pyramid shaped Cu2S film with hierarchical micro/nanostructures is formed on a commercial copper mesh. This film is formed by a spontaneous redox sul...

journal_title：Scientific reports

authors： Xu S,Sheng R,Cao Y,Yan J

更新日期：2019-08-28 00:00:00

abstract：:Recently, a concept of digital metamaterials has been proposed to manipulate field distribution through proper spatial mixtures of digital metamaterial bits. Here, we present a design of 2-bit digitally-controlled coding metasurface that can effectively modulate the scattered electromagnetic wave and realize different...

journal_title：Scientific reports

authors： Huang C,Sun B,Pan W,Cui J,Wu X,Luo X

更新日期：2017-02-08 00:00:00

abstract：:PC4 is an abundant single-strand DNA binding protein that has been implicated in transcription and DNA repair. Here, we show that PC4 is involved in the cellular DNA damage response. To elucidate the role, we used the DT40 chicken B cell model, which produces clustered DNA lesions at Ig loci via the action of activati...

journal_title：Scientific reports

authors： Caldwell RB,Braselmann H,Schoetz U,Heuer S,Scherthan H,Zitzelsberger H

更新日期：2016-07-04 00:00:00

abstract：:For more than 30 years, the remarkable superconducting properties of REBa2Cu3O7-x (RE = rare earth) compounds have triggered research studies across the world. Accordingly, significant progresses have been made both from a basic understanding and a fabrication processes perspective. Yet, today, the major technological...

journal_title：Scientific reports

authors： Fête A,Senatore C

更新日期：2018-12-07 00:00:00

abstract：:Visual field testing is an important endpoint in glaucoma clinical trials, and the testing paradigm used can have a significant impact on the sample size requirements. To investigate this, this study included 353 eyes of 247 glaucoma patients seen over a 3-year period to extract real-world visual field rates of change...

journal_title：Scientific reports

authors： Wu Z,Medeiros FA

更新日期：2018-03-20 00:00:00

abstract：:Human group-specific component protein (Gc protein) is a multifunctional serum protein which has three common allelic variants, Gc1F, Gc1S and Gc2 in humans. Gc1 contains an O-linked trisaccharide [sialic acid-galactose-N-acetylgalactosamine (GalNAc)] on the threonine420 (Thr420) residue and can be converted to a pote...

journal_title：Scientific reports

authors： Nabeshima Y,Abe C,Kawauchi T,Hiroi T,Uto Y,Nabeshima YI

更新日期：2020-11-05 00:00:00

abstract：:Although more than 1,000 androgen receptor (AR) mutations have been identified and these mutants are pathologically important, few theoretical studies have investigated the role of AR protein folding stability in disease and its relationship with the phenotype of the patients. Here, we extracted AR variant data from f...

journal_title：Scientific reports

authors： Chen F,Chen X,Jiang F,Leng F,Liu W,Gui Y,Yu J

更新日期：2020-07-21 00:00:00

abstract：:Light-sheet microscopy enables considerable speed and phototoxicity gains, while quantitative-phase imaging confers label-free recognition of cells and organelles, and quantifies their number-density that, thermodynamically, is more representative of metabolism than size. Here, we report the fusion of these two imagin...

journal_title：Scientific reports

authors： Subedi NR,Jung PS,Bredeweg EL,Nemati S,Baker SE,Christodoulides DN,Vasdekis AE

更新日期：2020-11-19 00:00:00

abstract：:Technological improvements have resulted in increased discovery of new microRNAs (miRNAs) and refinement and enrichment of existing miRNA families. miRNA families are important because they suggest a common sequence or structure configuration in sets of genes that hint to a shared function. Exploratory tools to enhanc...

journal_title：Scientific reports

authors： Kamanu TK,Radovanovic A,Archer JA,Bajic VB

更新日期：2013-10-15 00:00:00

abstract：:Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by the destruction of interlobular biliary ductules, which progressively leads to cholestasis, hepatic fibrosis, cirrhosis, and eventually liver failure. Several mouse models have been used to clarify the pathogenesis of PBC and are general...

journal_title：Scientific reports

authors： Ma WT,Liu QZ,Yang JB,Yang YQ,Zhao ZB,Ma HD,Gershwin ME,Lian ZX

更新日期：2017-11-10 00:00:00

abstract：:We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mφs). Non-alcoholic steatohepatitis (NASH) is characterized not only by hepatic steatosis but also chronic inflammation and fibrosis. In the ...

journal_title：Scientific reports

authors： Nakashima H,Nakashima M,Kinoshita M,Ikarashi M,Miyazaki H,Hanaka H,Imaki J,Seki S

更新日期：2016-10-06 00:00:00

abstract：:Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis. We detected PRL and PRLR in all GBM cell lines tested. PRLR activation or overexpression using plasmid tra...

journal_title：Scientific reports

authors： Asad AS,Nicola Candia AJ,Gonzalez N,Zuccato CF,Abt A,Orrillo SJ,Lastra Y,De Simone E,Boutillon F,Goffin V,Seilicovich A,Pisera DA,Ferraris MJ,Candolfi M

更新日期：2019-12-20 00:00:00

abstract：:Enamel proteins form a scaffold for growing hydroxyapatite crystals during enamel formation. They are then almost completely degraded during enamel maturation, resulting in a protein content of only 1% (w/v) in mature enamel. Nevertheless, this small amount of remaining proteins has important effects on the mechanical...

journal_title：Scientific reports

authors： Baumann T,Carvalho TS,Lussi A

更新日期：2015-10-15 00:00:00

abstract：:Early fruit development is crucial for crop production in tomato. After fertilization, the ovary undergoes cell division and cell expansion before maturation. Although the roles of regulatory signals such as hormone and carbohydrate during early fruit development have been studied, the spatial distribution and the seq...

journal_title：Scientific reports

authors： Zhang S,Xu M,Qiu Z,Wang K,Du Y,Gu L,Cui X

更新日期：2016-03-18 00:00:00

abstract：:We propose a deep learning model - Probabilistic Prognostic Estimates of Survival in Metastatic Cancer Patients (PPES-Met) for estimating short-term life expectancy (>3 months) of the patients by analyzing free-text clinical notes in the electronic medical record, while maintaining the temporal visit sequence. In a si...

journal_title：Scientific reports

authors： Banerjee I,Gensheimer MF,Wood DJ,Henry S,Aggarwal S,Chang DT,Rubin DL

更新日期：2018-07-03 00:00:00

abstract：:A new and facile approach to selectively functionalize the internal and external surfaces of porous silicon (pSi) for drug delivery applications is reported. To provide a surface that is suitable for sustained drug release of the hydrophobic cancer chemotherapy drug camptothecin (CPT), the internal surfaces of pSi fil...

journal_title：Scientific reports

authors： Zhang DX,Yoshikawa C,Welch NG,Pasic P,Thissen H,Voelcker NH

更新日期：2019-02-04 00:00:00

abstract：:Technological advances have made it possible to examine dental resin composites using 3D nanometer resolution. This investigation aims to characterize existing dental nano-hybrid and micro-hybrid resin composites through comparing and contrasting nano-computed tomography (nano-CT) with micro-CT and high-resolution SEM...

journal_title：Scientific reports

authors： Haugen HJ,Qasim SB,Matinlinna JP,Vallittu P,Nogueira LP

更新日期：2020-09-23 00:00:00