Abstract:
:Power consumption is the main limitation in the development of new high performance random access memory for portable electronic devices. Magnetic RAM (MRAM) with CoFeB/MgO based magnetic tunnel junctions (MTJs) is a promising candidate for reducing the power consumption given its non-volatile nature while achieving high performance. The dynamic properties and switching mechanisms of MTJs are critical to understanding device operation and to enable scaling of devices below 30 nm in diameter. Here we show that the magnetic reversal mechanism is incoherent and that the switching is thermally nucleated at device operating temperatures. Moreover, we find an intrinsic thermal switching field distribution arising on the sub-nanosecond time-scale even in the absence of size and anisotropy distributions or material defects. These features represent the characteristic signature of the dynamic properties in MTJs and give an intrinsic limit to reversal reliability in small magnetic nanodevices.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Meo A,Chureemart P,Wang S,Chepulskyy R,Apalkov D,Chantrell RW,Evans RFLdoi
10.1038/s41598-017-16911-3subject
Has Abstractpub_date
2017-12-01 00:00:00pages
16729issue
1issn
2045-2322pii
10.1038/s41598-017-16911-3journal_volume
7pub_type
杂志文章abstract::To investigate the particle size distribution of particulate matter and the concentration of specific perfluorinated compounds in indoor dust samples from several locations. Then, we used cell-based assays to investigate the effect of perfluorinated compounds on human corneal epithelial (HCEpiC), endothelial cells (HC...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-72600-8
更新日期:2020-09-24 00:00:00
abstract::Adaptive responses to hypoxia regulate hepatic lipid metabolism, but their consequences in nonalcoholic fatty liver disease (NAFLD) are largely unknown. Here, we show that hypoxia inducible factor-1 (HIF-1), a key determinant of hypoxic adaptations, prevents excessive hepatic lipid accumulation in the progression of N...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32586-w
更新日期:2018-09-21 00:00:00
abstract::The gut of Drosophila melanogaster includes a proximal acidic region (~pH 2), however the genome lacks the H(+)/K(+) ATPase characteristic of the mammalian gastric parietal cell, and the molecular mechanisms of acid generation are poorly understood. Here, we show that maintenance of the low pH of the acidic region is ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27242
更新日期:2016-06-02 00:00:00
abstract::Environmental contamination of arsenic (As) and its accumulation in rice (Oryza sativa L.) is of serious human health concern. In planta speciation of As is an important tool to understand As metabolism in plants. In the present study, we investigated root to shoot As translocation and speciation in rice exposed to in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40522
更新日期:2017-01-17 00:00:00
abstract::Hypoxia-inducible factor (HIF)-1α and HIF-2α play an important role in liver fibrosis. von Hippel-Lindau protein (VHL), a key mediator of HIF-α, regulates fibrosis in an organ- and cell-specific way. In this study, human liver samples were collected from hepatitis C-, alcoholic-, and cholestatic-associated fibrotic an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41038
更新日期:2017-01-23 00:00:00
abstract::Bone metastasis of breast cancer cells is a major concern, as it causes increased morbidity and mortality in patients. Bone tissue-derived CXCL12 preferentially recruits breast cancer cells expressing CXCR4 to bone metastatic sites. Thus, understanding how CXCR4 expression is regulated in breast cancer cells could sug...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09170
更新日期:2015-03-16 00:00:00
abstract::The enzyme alanine racemase (Alr) has been a new target for the development of antibacterial drugs based on the involvement of D-Ala in bacterial cell wall biosynthesis. Our previous study noted that Alr is essential for the growth and interspecies competitiveness of S. mutans, the major causative organism of dental c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24295-1
更新日期:2018-04-13 00:00:00
abstract::Macroevolutionary studies of insects at diverse taxonomic scales often reveal dynamic evolutionary patterns, with multiple inferred diversification rate shifts. Responses to major past environmental changes, such as the Cretaceous Terrestrial Revolution, or the development of major key innovations, such as wings or co...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19208
更新日期:2016-01-18 00:00:00
abstract::Optogenetics allows precise, fast and reversible intervention in biological processes. Light-sheet microscopy allows observation of the full course of Drosophila embryonic development from egg to larva. Bringing the two approaches together allows unparalleled precision into the temporal regulation of signaling pathway...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16879-0
更新日期:2017-11-30 00:00:00
abstract::Sensory development of the human brain begins prenatally, allowing cortical auditory responses to be recorded at an early age in preterm infants. Despite several studies focusing on the temporal characteristics of preterm infants' cortical responses, few have been conducted on frequency analysis of these responses. In...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47064-0
更新日期:2019-07-23 00:00:00
abstract::Metallic nanostructures are of immense scientific interest owing to unexpectedly strong interaction with light in deep subwavelength scales. Resonant excitations of surface and cavity plasmonic modes mediate strong light localization in nanoscale objects. Nevertheless, the role of surface plasmon-polaritons (SPP) in l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05683
更新日期:2014-07-14 00:00:00
abstract::The purpose of this study is to investigate whether implementing a myofascial release (MFR) protocol designed to restore the myofascial properties of the diaphragm has any effect on the symptoms, quality of life, and consumption of proton pump inhibitors (PPI) drugs by patients with non-erosive gastroesophageal reflux...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-019-43799-y
更新日期:2019-05-13 00:00:00
abstract::In fish, the fat content contributes to promoting the nutritional and organoleptic characteristics of the flesh, which is crucial for consumer acceptance. Methods to predict the fat in fish are important in nutritional and physiological research, where body content is traditionally determined by dissection followed by...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67435-2
更新日期:2020-06-29 00:00:00
abstract::Bacteria swim in sequences of straight runs that are interrupted by turning events. They drive their swimming locomotion with the help of rotating helical flagella. Depending on the number of flagella and their arrangement across the cell body, different run-and-turn patterns can be observed. Here, we present fluoresc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16428-9
更新日期:2017-12-01 00:00:00
abstract::Effective treatment of osteomyelitis remains a formidable clinical challenge. The rapid emergence of multidrug-resistant bacteria has renewed interest in developing antimicrobial biomaterials using antiseptic silver ions to treat osteomyelitis. However, inadequate local retention and severe cytotoxic effects have limi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39174
更新日期:2016-12-16 00:00:00
abstract::Network structure has often proven to be important in understanding the decision behavior of individuals or agents in different interdependent situations. Computational studies predict that network structure has a crucial influence on behavior in iterated 2 by 2 asymmetric 'battle of the sexes' games. We test such beh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43260-0
更新日期:2019-05-02 00:00:00
abstract::Retinal diseases generally are vision-threatening conditions that warrant appropriate clinical decision-making which currently solely dependents upon extensive clinical screening by specialized ophthalmologists. In the era where molecular assessment has improved dramatically, we aimed at the identification of biomarke...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41595
更新日期:2017-01-27 00:00:00
abstract::Magnetic small-angle neutron scattering (SANS) is a powerful technique for investigating magnetic nanoparticle assemblies in nonmagnetic matrices. For such microstructures, the standard theory of magnetic SANS assumes uniformly magnetized nanoparticles (macrospin model). However, there exist many experimental and theo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13457-2
更新日期:2017-10-12 00:00:00
abstract::Nuclear distribution element-like 1 (Ndel1) plays pivotal roles in diverse biological processes and is implicated in the pathogenesis of multiple neurodevelopmental disorders. Ndel1 function by regulating microtubules and intermediate filaments; however, its functional link with the actin cytoskeleton is largely unkno...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31827
更新日期:2016-08-22 00:00:00
abstract::We have developed an optimized protocol for plasma targeted mRNA sequencing in our previous study. Here, we performed plasma targeted mRNA sequencing for 40 colorectal adenoma patients and 39 colonoscopy-proven normal controls in order to find potential circulating mRNA markers for colorectal adenoma. Results showed t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49445-x
更新日期:2019-09-10 00:00:00
abstract::Precisely controlling the protein-nanomaterial interactions at selective sites is crucial in engineering biomolecule composite architectures with tailored nanostructures and functions for a variety of biomedical applications. This strategy, however, is only beginning to be explored. Here, we demonstrate the facet-spec...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep05084
更新日期:2014-05-28 00:00:00
abstract::We performed two phase I trials of the histone deacetylase inhibitor vorinostat combined with either the vascular endothelial growth factor inhibitor pazopanib (NCT01339871) or the proteasome inhibitor ixazomib (NCT02042989) in patients with metastatic TP53 mutant solid tumors. Both trials followed a 3 + 3 dose-escala...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58366-z
更新日期:2020-02-20 00:00:00
abstract::The evolution of cooperation requires some mechanism that reduces the risk of exploitation for cooperative individuals. Recent studies have shown that men with wide faces are anti-social, and they are perceived that way by others. This suggests that people could use facial width to identify anti-social men and thus li...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01047
更新日期:2013-01-01 00:00:00
abstract::Deep venous thrombosis (DVT) is a common complication of orthopedic surgery. Genetic risk factors and high heritability carried a substantial risk of DVT. In this study, we aimed to investigate the potential association in the Han Chinese population between the polymorphisms of BDKRB2 and KNG1 and DVT after orthopedic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34868-9
更新日期:2018-11-26 00:00:00
abstract::Tremendous efforts have been made to explore biomarkers for classification and grading on gliomas. The goal of this study was to identify more molecular features that are associated with clinical outcomes by comparing the genomic profiles of primary and recurrent gliomas and determine potential recurrence leading fact...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/s41598-019-52515-9
更新日期:2019-11-05 00:00:00
abstract::We report an experimental demonstration of positive-negative sub-wavelength interference without correlation. Typically, people can achieve sub-wavelength effects with correlation measurement no matter by using bi-photon or thermal light sources. In this paper, we adopt a thermal light source, and we count the realiza...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82030-9
更新日期:2021-01-28 00:00:00
abstract::Pertuzumab is an antihuman HER2 antibody developed for HER2 positive breast cancer. Glycosylation profiles are always the important issue for antibody based therapy. Previous findings have suggested the impact of glycosylation profiles on the function of antibodies, like pharmacodynamics, antibody-dependent cellular c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46347
更新日期:2017-04-11 00:00:00
abstract::Resin composites containing reinforcing inert glass fillers combined with bioactive glass (BG) can aid in the prevention of secondary caries, which is a major cause of failure of contemporary composite restorations. A series of previous studies on experimental resin composites filled with BG 45S5 has demonstrated that...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54035-y
更新日期:2019-11-21 00:00:00
abstract::Ischemic stroke and diabetes are vascular risk factors for the development of impaired memory such as dementia and/or Alzheimer's disease. Clinical studies have demonstrated that minor striatal ischemic lesions in combination with β-amyloid (Aβ) load are critical in generating cognitive deficits. These cognitive defic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22985-4
更新日期:2018-03-23 00:00:00
abstract::The association between alcohol consumption and kidney function is intriguing, but study results are mixed and controversial. We examined the association of alcohol consumption with the overall change in kidney function over 12 years. We analyzed data from a population-based cohort that was part of the Korean Genome a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81777-5
更新日期:2021-01-27 00:00:00