Evaluation of BMMSCs-EPCs sheets for repairing alveolar bone defects in ovariectomized rats.

abstract：:Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...

journal_title：Scientific reports

authors： Duca F,Zotter-Tufaro C,Kammerlander AA,Aschauer S,Binder C,Mascherbauer J,Bonderman D

更新日期：2018-01-18 00:00:00

abstract：:The inconsistent findings on the association between COMT (catecholamine-O-methyl-transferase) and suicidal behaviour gave reason to choose a clear phenotype description of suicidal behaviour and take childhood maltreatment as environmental factor into account. The aim of this candidate-gene-association study was to e...

journal_title：Scientific reports

authors： Bernegger A,Kienesberger K,Carlberg L,Swoboda P,Ludwig B,Koller R,Inaner M,Zotter M,Kapusta N,Aigner M,Haslacher H,Kasper S,Schosser A

更新日期：2018-01-12 00:00:00

abstract：:We here investigated whether the unique capacity of mesenchymal stem cells (MSCs) to re-establish tissue homeostasis depends on their potential to sense danger associated molecular pattern (DAMP) and to mount an adaptive response in the interest of tissue repair. Unexpectedly, after injection of MSCs which had been pr...

journal_title：Scientific reports

authors： Basu A,Munir S,Mulaw MA,Singh K,Crisan D,Sindrilaru A,Treiber N,Wlaschek M,Huber-Lang M,Gebhard F,Scharffetter-Kochanek K

更新日期：2018-04-18 00:00:00

abstract：:In this paper, three plastomes of Mankyua chejuense, Helminthostachys zeylanica, and Botrychium ternatum in Ophioglossaceae were completely sequenced in order to investigate the plastome evolution and phylogeny of eusporangiate ferns. They were similar to each other in terms of length and the gene orders; however, six...

journal_title：Scientific reports

authors： Kim HT,Kim KJ

更新日期：2018-11-07 00:00:00

abstract：:Little research on coronaviruses has been conducted on wild animals in Africa. Here, we screened a wide range of wild animals collected in six provinces and five caves of Gabon between 2009 and 2015. We collected a total of 1867 animal samples (cave-dwelling bats, rodents, non-human primates and other wild animals). W...

journal_title：Scientific reports

authors： Maganga GD,Pinto A,Mombo IM,Madjitobaye M,Mbeang Beyeme AM,Boundenga L,Ar Gouilh M,N'Dilimabaka N,Drexler JF,Drosten C,Leroy EM

更新日期：2020-04-30 00:00:00

abstract：:Inflammatory and metabolic diseases can originate during early-life and have been correlated with shifts in intestinal microbial ecology. Here we demonstrate that minor environmental fluctuations during the early neonatal period had sustained effects on the developing porcine microbiota and host-microbe interface. The...

journal_title：Scientific reports

authors： Lewis MC,Merrifield CA,Berger B,Cloarec O,Duncker S,Mercenier A,Nicholson JK,Holmes E,Bailey M

更新日期：2017-07-13 00:00:00

abstract：:Mapping the location of bound cellulase enzymes provides information on the micro-scale distribution of amenable and recalcitrant sites in pretreated woody biomass for biofuel applications. The interaction of a fluorescently labelled cellulase enzyme cocktail with steam-exploded pine (SEW) was quantified using confoca...

journal_title：Scientific reports

authors： Donaldson L,Vaidya A

更新日期：2017-03-10 00:00:00

abstract：:This study investigates the relationship between objective cognitive impairment (OCI), subjective cognitive complaints and depressive symptoms in men and women with classical and non-classical Fabry disease (FD). Cognitive functioning was assessed using a neuropsychological test battery, subjective cognitive complaint...

journal_title：Scientific reports

authors： Körver S,Geurtsen GJ,Hollak CEM,van Schaik IN,Longo MGF,Lima MR,Vedolin L,Dijkgraaf MGW,Langeveld M

更新日期：2019-01-17 00:00:00

abstract：:Nitric oxide (NO) produced by endothelial cells in response to cytokines displays anti-inflammatory activity by preventing the adherence, migration and activation of neutrophils. The molecular mechanism by which NO operates at the blood-endothelium interface to exert anti-inflammatory properties is largely unknown. He...

journal_title：Scientific reports

authors： Lai TS,Lindberg RA,Zhou HL,Haroon ZA,Dewhirst MW,Hausladen A,Juang YL,Stamler JS,Greenberg CS

更新日期：2017-11-23 00:00:00

abstract：:We report a strategy to achieve a discrete cage molecule featuring a high level of structural hierarchy through a multiple-assembly process. A cobalt (Co) supramolecular triple-stranded helicate (Co-TSH)-based discrete molecular cage (1) is successfully synthesized and fully characterized. The solid-state structure of...

journal_title：Scientific reports

authors： Mai HD,Kang P,Kim JK,Yoo H

更新日期：2017-03-06 00:00:00

abstract：:With the reduction of oil and gas reserves and the increase of mining difficulty in Northern China, the carbonate rocks in Southern North China Basin are becoming a significant exploration target for carbonate reservoirs. However, the development characteristics, formation stages, formation environments and mechanisms...

journal_title：Scientific reports

authors： Zhang H,Xu G,Liu M,Wang M

更新日期：2021-01-12 00:00:00

abstract：:Geometric frustration, in which competing interactions give rise to degenerate ground states, potentially induces various exotic quantum phenomena in magnetic materials. Minimal models comprising triangular units, such as triangular and Kagome lattices, have been investigated for decades to realize novel quantum phase...

journal_title：Scientific reports

authors： Yamaguchi H,Okubo T,Kittaka S,Sakakibara T,Araki K,Iwase K,Amaya N,Ono T,Hosokoshi Y

更新日期：2015-10-15 00:00:00

abstract：:Efficient mitochondrial Ca2+ uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca2+ transfer increases during the early phase of ER stress induced by tunicamycin as an adapt...

journal_title：Scientific reports

authors： Bravo-Sagua R,López-Crisosto C,Parra V,Rodriguez-Peña M,Rothermel BA,Quest AF,Lavandero S

更新日期：2016-11-03 00:00:00

abstract：:Genomic selection (GS) by selecting lines prior to field phenotyping using genotyping data has the potential to enhance the rate of genetic gains. Genotype × environment (G × E) interaction inclusion in GS models can improve prediction accuracy hence aid in selection of lines across target environments. Phenotypic dat...

journal_title：Scientific reports

authors： Roorkiwal M,Jarquin D,Singh MK,Gaur PM,Bharadwaj C,Rathore A,Howard R,Srinivasan S,Jain A,Garg V,Kale S,Chitikineni A,Tripathi S,Jones E,Robbins KR,Crossa J,Varshney RK

更新日期：2018-08-03 00:00:00

abstract：:Immune parameters show characteristic normal baseline levels and variance in the population. We characterised the degree of inter-individual and within-individual variation over one-year time period in 33 immune cell subsets by flow cytometry in peripheral blood mononuclear cells from 43 healthy young adult volunteers...

journal_title：Scientific reports

authors： Kanodia P,Kaur G,Coshic P,Chatterjee K,Neeman T,George A,Rath S,Bal V,Prabhu SB

更新日期：2019-10-14 00:00:00

abstract：:Two objects can be distinguished if they have different measurable properties. Thus, distinguishability depends on the Physics of the objects. In considering graphs, we revisit the Ising model as a framework to define physically meaningful spectral invariants. In this context, we introduce a family of refinements of t...

journal_title：Scientific reports

authors： Vinci W,Markström K,Boixo S,Roy A,Spedalieri FM,Warburton PA,Severini S

更新日期：2014-07-16 00:00:00

abstract：:The neural hard-wired pathways in which the lymphoid organs are innervated by the nervous system is of special interest with respect to suggested afferent and sensory systems informing the central nervous system about the status of the immune system. Until today efferent also like afferent innervation seem to be unspe...

journal_title：Scientific reports

authors： Wülfing C,Günther HS

更新日期：2015-11-19 00:00:00

abstract：:The number and subtype composition of N-methyl-d-aspartate receptor (NMDAR) at synapses determines their functional properties and role in learning and memory. Genetically increased or decreased amount of GluN2B affects hippocampus-dependent memory in the adult brain. But in some experimental conditions (e.g., memory ...

journal_title：Scientific reports

authors： Sun YY,Cai W,Yu J,Liu SS,Zhuo M,Li BM,Zhang XH

更新日期：2016-08-04 00:00:00

abstract：:Many chemical reactions in biological cells occur at very low concentrations of constituent molecules. Thus, transcriptional gene-regulation is often controlled by poorly expressed transcription-factors, such as E.coli lac repressor with few tens of copies. Here we study the effects of inherent concentration fluctuati...

journal_title：Scientific reports

authors： Pulkkinen O,Metzler R

更新日期：2015-12-04 00:00:00

abstract：:Clinical benefit from trastuzumab and other anti-human epidermal growth factor receptor-2 (HER2) therapies in patients with HER2-positive gastric cancer (GC) remains limited by primary or acquired resistance. We aimed to investigate the impact of concomitant molecular alterations to HER2 amplification on the clinical ...

journal_title：Scientific reports

authors： Lee JY,Hong M,Kim ST,Park SH,Kang WK,Kim KM,Lee J

更新日期：2015-03-19 00:00:00

abstract：:The aim of this study was to identify the synergistic effect of microRNA expression with classical risk factors of coronary heart disease (CHD) and to explore their diagnostic value for coronary stenotic lesions in subjects with CHD. Plasma samples were obtained from 66 subjects with CHD and from 58 control individual...

journal_title：Scientific reports

authors： Ding XQ,Ge PC,Liu Z,Jia H,Chen X,An FH,Li LH,Chen ZH,Mao HW,Li ZY,Gu Y,Zhu TB,Li CJ,Wang LS,Ma WZ,Yang ZJ,Jia EZ

更新日期：2015-10-08 00:00:00

abstract：:Deoxynivalenol (DON) is one of the most abundant mycotoxins and exerts many adverse effects on humans and animals. To date, the transporting mechanism of DON in mammalian cells remains unclear. In this study, the parallel artificial membrane permeability assay (PAMPA), Transwell models and metabolic inhibitors were us...

journal_title：Scientific reports

authors： Li X,Mu P,Wen J,Deng Y

更新日期：2017-07-19 00:00:00

abstract：:Habitat fragmentation can reduce population viability, especially for area-sensitive species. The Minimum Area Requirements (MAR) of a population is the area required for the population's long-term persistence. In this study, the response of occupancy probability of giant pandas against habitat patch size was studied ...

journal_title：Scientific reports

authors： Qing J,Yang Z,He K,Zhang Z,Gu X,Yang X,Zhang W,Yang B,Qi D,Dai Q

更新日期：2016-12-08 00:00:00

abstract：:Elucidating arbuscular mycorrhizal (AM) fungal responses to elevation changes is critical to improve understanding of microbial function in ecosystems under global asymmetrical climate change scenarios. Here we examined AM fungal community in a two-year reciprocal translocation of vegetation-intact soil blocks along a...

journal_title：Scientific reports

authors： Yang W,Zheng Y,Gao C,Duan JC,Wang SP,Guo LD

更新日期：2016-11-09 00:00:00

abstract：:Improving surface sensitivities of nanostructure-based plasmonic sensors is an important issue to be addressed. Among the SPR measurements, the wavelength interrogation is commonly utilized. We proposed using blue-shifted surface plasmon mode and Fano resonance, caused by the coupling of a cavity mode (angle-independe...

journal_title：Scientific reports

authors： Lee KL,Chang CC,You ML,Pan MY,Wei PK

更新日期：2018-06-27 00:00:00

abstract：:Irreversible electroporation (IRE) is an emerging focal therapy which is demonstrating utility in the treatment of unresectable tumors where thermal ablation techniques are contraindicated. IRE uses ultra-short duration, high-intensity monopolar pulsed electric fields to permanently disrupt cell membranes within a wel...

journal_title：Scientific reports

authors： Sano MB,Arena CB,Bittleman KR,DeWitt MR,Cho HJ,Szot CS,Saur D,Cissell JM,Robertson J,Lee YW,Davalos RV

更新日期：2015-10-13 00:00:00

abstract：:Methylated non-CpGs (mCpH; H means A, C, and T) have emerged as key epigenetic marks in mammalian embryonic stem cells (ESCs) and neurons, regulating cell type-specific functions. In these two cell types, mCpHs show distinct motifs and correlations to transcription that could be a key in understanding the cell type-sp...

journal_title：Scientific reports

authors： Lee JH,Park SJ,Nakai K

更新日期：2017-09-12 00:00:00

abstract：:Long-term supply of synthetic nitrogen (N) has the potential to affect the soil N processes. This study aimed to (i) establish N response curves to find the best balance between inputs and outputs of N over four ratoons; (ii) use 15N-labeled fertilizer to estimate the N recovery efficiency of fertilizer applied in the...

journal_title：Scientific reports

authors： Joris HAW,Vitti AC,Ferraz-Almeida R,Otto R,Cantarella H

更新日期：2020-11-02 00:00:00

abstract：:Urate transporter 1 (URAT1/SLC22A12), a urate transporter gene, is a causative gene for renal hypouricemia type 1. Among several reported nonsynonymous URAT1 variants, R90H (rs121907896) and W258X (rs121907892) are frequent causative mutations for renal hypouricemia. However, no case-control study has evaluated the re...

journal_title：Scientific reports

authors： Sakiyama M,Matsuo H,Shimizu S,Nakashima H,Nakamura T,Nakayama A,Higashino T,Naito M,Suma S,Hishida A,Satoh T,Sakurai Y,Takada T,Ichida K,Ooyama H,Shimizu T,Shinomiya N

更新日期：2016-01-29 00:00:00

abstract：:Since the re-emergence of Zika virus in 2014 and subsequent association with microcephaly, much work has focused on the development of a vaccine to halt its spread throughout the world. The mosquito vector that transmits this virus is widespread and responsible for the spread of other arboviridae including Dengue. Cur...

journal_title：Scientific reports

authors： Oom AL,Smith D,Akrami K

更新日期：2017-07-24 00:00:00