Evolution of Tandem Repeat Satellite Sequences in Two Closely Related Caenorhabditis Species. Diminution of Satellites in Hermaphrodites.

abstract：:Ring chromosome 8 (r(8)) is one of the least frequent ring chromosomes. Usually, maternal chromosome 8 forms a ring, which can be lost from cells due to mitotic instability. The 8q24 region contains the imprinted KCNK9 gene, which is expressed from the maternal allele. Heterozygous KCNK9 mutations are associated with ...

journal_title：Genes

authors： Kashevarova AA,Nikitina TV,Mikhailik LI,Belyaeva EO,Vasilyev SA,Lopatkina ME,Fedotov DA,Fonova EA,Zarubin AA,Sivtsev AA,Skryabin NA,Nazarenko LP,Lebedev IN

更新日期：2020-12-09 00:00:00

abstract：:The efficient extraction of DNA from challenging samples, such as bones, is critical for the success of downstream genotyping analysis in molecular genetic disciplines. Even though the ancient DNA community has developed several protocols targeting small DNA fragments that are typically present in decomposed or old sp...

journal_title：Genes

authors： Xavier C,Eduardoff M,Bertoglio B,Amory C,Berger C,Casas-Vargas A,Pallua J,Parson W

更新日期：2021-01-22 00:00:00

abstract：:The spectrum of modern horse populations encompasses populations with a long history of development in isolation and relatively recently formed types. To increase our understanding of the evolutionary history and provide information on how to optimally conserve or improve these populations with varying development and...

journal_title：Genes

authors： Schurink A,Shrestha M,Eriksson S,Bosse M,Bovenhuis H,Back W,Johansson AM,Ducro BJ

更新日期：2019-06-25 00:00:00

abstract：:Gene duplication is an important evolutionary mechanism allowing to provide new genetic material and thus opportunities to acquire new gene functions for an organism, with major implications such as speciation events. Various processes are known to allow a gene to be duplicated and different models explain how duplica...

journal_title：Genes

authors： Lallemand T,Leduc M,Landès C,Rizzon C,Lerat E

更新日期：2020-09-04 00:00:00

abstract：:Osteoarthritis (OA) is a widely prevalent disease worldwide, and with an increasingly ageing society, it has become a challenge for the field of regenerative medicine. OA is a disease process involving multiple joint tissues, including those not visible on radiography, and is a complex disease process with multiple ph...

journal_title：Genes

authors： Borić I,Hudetz D,Rod E,Jeleč Ž,Vrdoljak T,Skelin A,Polašek O,Plečko M,Trbojević-Akmačić I,Lauc G,Primorac D

更新日期：2019-12-17 00:00:00

abstract：:Aminoacyl-tRNA synthetases (aaRSs) are key enzymes in the mRNA translation machinery, yet they possess numerous non-canonical functions developed during the evolution of complex organisms. The aaRSs and aaRS-interacting multi-functional proteins (AIMPs) are continually being implicated in tumorigenesis, but these conn...

journal_title：Genes

authors： Wang J,Vallee I,Dutta A,Wang Y,Mo Z,Liu Z,Cui H,Su AI,Yang XL

更新日期：2020-11-22 00:00:00

abstract：:A 9-month old male Jack Russell Terrier started showing paraparesis of the hindlimbs after a walk. Hospitalized, the dog went into cardiac arrest, and later died. Necroscopic examination revealed a severe thickness of the diaphragm, esophagus, and base of the tongue, leading to the diagnosis of muscular dystrophy. The...

journal_title：Genes

authors： Brunetti B,Muscatello LV,Letko A,Papa V,Cenacchi G,Grillini M,Murgiano L,Jagannathan V,Drögemüller C

更新日期：2020-10-08 00:00:00

abstract：:Rapeseed contains glucosinolates, a toxic group of sulfur-containing glucosides, which play critical roles in defense against herbivores and microbes. However, the presence of glucosinolates in rapeseed reduces the value of the meal as feed for livestock. We performed association mapping of seed glucosinolate (GS) con...

journal_title：Genes

authors： Qu CM,Li SM,Duan XJ,Fan JH,Jia LD,Zhao HY,Lu K,Li JN,Xu XF,Wang R

更新日期：2015-11-18 00:00:00

abstract：:Golgi reassembly and stacking protein (GRASP) is required for polysaccharide secretion and virulence in Cryptococcus neoformans. In fungal species, extracellular vesicles (EVs) participate in the export of polysaccharides, proteins and RNA. In the present work, we investigated if EV-mediated RNA export is functionally...

journal_title：Genes

authors： Peres da Silva R,Martins ST,Rizzo J,Dos Reis FCG,Joffe LS,Vainstein M,Kmetzsch L,Oliveira DL,Puccia R,Goldenberg S,Rodrigues ML,Alves LR

更新日期：2018-08-08 00:00:00

abstract：:Cell Division Autoantigen 1 (CDA1) was discovered following screening a human expression library with serum from a patient with Discoid Lupus Erythematosus. CDA1, encoded by TSPYL2 on the X chromosome, shares anti-proliferative and pro‑fibrotic properties with TGF-b. It inhibits cell growth through p53, pERK1/2 and p2...

journal_title：Genes

authors： Toh BH,Tu Y,Cao Z,Cooper ME,Chai Z

更新日期：2010-09-30 00:00:00

abstract：:Fat deposition in pigs, which significantly contributes to meat quality, fattening efficiency, reproductive performance, and immunity, is critically affected by preadipocyte adipogenic differentiation. We elucidated adipogenesis in pigs using transcriptome analysis. Preadipocytes from subcutaneous adipose tissue (SAT)...

journal_title：Genes

authors： Zhao X,Chen S,Tan Z,Wang Y,Zhang F,Yang T,Liu Y,Ao H,Xing K,Wang C

更新日期：2019-07-19 00:00:00

abstract：:The transition from a dormant to a germinating seed represents a crucial developmental switch in the life cycle of a plant. Subsequent transition from a germinating seed to an autotrophic organism also requires a robust and multi-layered control. Seed germination and seedling growth are multistep processes, involving ...

journal_title：Genes

authors： Longo C,Holness S,De Angelis V,Lepri A,Occhigrossi S,Ruta V,Vittorioso P

更新日期：2020-12-31 00:00:00

abstract：:The Muraenidae is one of the largest and most complex anguilliform families. Despite their abundance and important ecological roles, morays are little studied, especially cytogenetically, and both their phylogenetic relationships and the taxonomy of their genera are controversial. With the aim of extending the karyolo...

journal_title：Genes

authors： Coluccia E,Deidda F,Lobina C,Melis R,Porcu C,Agus B,Salvadori S

更新日期：2020-11-06 00:00:00

abstract：:Autoimmune blistering dermatoses (ABDs) are characterized by autoantibodies to keratinocyte surface antigens and molecules within the dermal-epidermal junction causing disruption of skin integrity. The affinity of Fc receptors (FcRs) causing an autoimmune response in ABDs may vary based on single-nucleotide polymorphi...

journal_title：Genes

authors： Gornowicz-Porowska J,Kowalczyk MJ,Seraszek-Jaros A,Bowszyc-Dmochowska M,Kaczmarek E,Żaba R,Dmochowski M

更新日期：2020-03-30 00:00:00

abstract：:Small RNAs play an important role in regulating plant responses to abiotic stress. Depending on the method of salt application, whether sudden or gradual, plants may experience either salt shock or salt stress, respectively. In this study, small RNA expression in response to salt shock and long-term salt stress in par...

journal_title：Genes

authors： Yin Z,Han X,Li Y,Wang J,Wang D,Wang S,Fu X,Ye W

更新日期：2017-12-05 00:00:00

abstract：:Induced point mutations are important genetic resources for their ability to create hypo- and hypermorphic alleles that are useful for understanding gene functions and breeding. However, such mutant populations have only been developed for a few temperate maize varieties, mainly B73 and W22, yet no tropical maize inbr...

journal_title：Genes

authors： Tran QH,Bui NH,Kappel C,Dau NTN,Nguyen LT,Tran TT,Khanh TD,Trung KH,Lenhard M,Vi SL

更新日期：2020-03-06 00:00:00

abstract：:Mobile DNA elements play a significant evolutionary role by promoting genome plasticity. Insertion sequences are the smallest prokaryotic transposable elements. They are highly diverse elements, and the ability to accurately identify, annotate, and infer the full genomic impact of insertion sequences is lacking. Halan...

journal_title：Genes

authors： Sadler M,R Mormile M,L Frank R

更新日期：2020-04-29 00:00:00

abstract：:The multiple organellar RNA editing factors (MORF) gene family plays a key role in organelle RNA editing in flowering plants. MORF genes expressions are also affected by abiotic stress. Although seven OsMORF genes have been identified in rice, few reports have been published on their expression patterns in different t...

journal_title：Genes

authors： Zhang Q,Shen L,Ren D,Hu J,Chen G,Zhu L,Gao Z,Zhang G,Guo L,Zeng D,Qian Q

更新日期：2019-09-10 00:00:00

abstract：:Pancreatic ductal adenocarcinoma is an extremely aggressive disease with a high metastatic potential. Most patients are diagnosed with metastatic disease, at which the five-year survival rate is only 3%. A better understanding of the mechanisms that drive metastasis is imperative for the development of better therapeu...

journal_title：Genes

authors： Ayres Pereira M,Chio IIC

更新日期：2019-12-19 00:00:00

abstract：:While the number of mammalian genome assemblies has proliferated, Y-chromosome assemblies have lagged behind. This discrepancy is caused by biological features of the Y-chromosome, such as its high repeat content, that present challenges to assembly with short-read, next-generation sequencing technologies. Partial Y-c...

journal_title：Genes

authors： Rando HM,Wadlington WH,Johnson JL,Stutchman JT,Trut LN,Farré M,Kukekova AV

更新日期：2019-05-28 00:00:00

abstract：:As a major infectious disease in chickens, Newcastle disease virus (NDV) causes considerable economic losses in the poultry industry, especially in developing countries where there is limited access to effective vaccination. Therefore, enhancing resistance to the virus in commercial chickens through breeding is a prom...

journal_title：Genes

authors： Zhang J,Kaiser MG,Gallardo RA,Kelly TR,Dekkers JCM,Zhou H,Lamont SJ

更新日期：2020-08-26 00:00:00

abstract：:Intercellular karyotypic variability has been a focus of genetic research for more than 50 years. It has been repeatedly shown that chromosome heterogeneity manifesting as chromosomal mosaicism is associated with a variety of human diseases. Due to the ability of changing dynamically throughout the ontogeny, chromosom...

journal_title：Genes

authors： Iourov IY,Vorsanova SG,Yurov YB,Kutsev SI

更新日期：2019-05-19 00:00:00

abstract：:The yeast Exophiala dermatitidis exhibits high resistance to γ-radiation in comparison to many other fungi. Several aspects of this phenotype have been characterized, including its dependence on homologous recombination for the repair of radiation-induced DNA damage, and the transcriptomic response invoked by acute γ-...

journal_title：Genes

authors： Schultzhaus ZS,Schultzhaus JN,Romsdahl J,Chen A,Hervey Iv WJ,Leary DH,Wang Z

更新日期：2020-09-25 00:00:00

abstract：:Vitellogenin receptors (VgRs) play critical roles in egg formation by transporting vitellogenin (Vg) into oocytes in insects. Although the function of VgR in insects is well studied, the transcriptional regulation of this gene is still unclear. Here, we cloned the promoter of the VgR gene from Bombyx mori (BmVgR), and...

journal_title：Genes

authors： Shen G,Chen E,Ji X,Liu L,Liu J,Hua X,Li D,Xiao Y,Xia Q

更新日期：2020-04-06 00:00:00

abstract：:Genome wide association studies (GWAS) are a well established methodology to identify genomic variants and genes that are responsible for traits of interest in all branches of the life sciences. Despite the long time this methodology has had to mature the reliable detection of genotype-phenotype associations is still ...

journal_title：Genes

authors： Ramzan F,Gültas M,Bertram H,Cavero D,Schmitt AO

更新日期：2020-08-05 00:00:00

abstract：:The homeodomain-leucine zipper (HD-Zip) transcription factor family is a key transcription factor family and unique to the plant kingdom. It consists of a homeodomain and a leucine zipper that serve in combination as a dimerization motif. The family can be classified into four subfamilies, and these subfamilies partic...

journal_title：Genes

authors： Song A,Li P,Xin J,Chen S,Zhao K,Wu D,Fan Q,Gao T,Chen F,Guan Z

更新日期：2016-05-17 00:00:00

abstract：:As a highly nutritious crop, Tartary buckwheat (Fagopyrum tartaricum) strongly adapts and grows in adverse environments and is widely grown in Asia. However, its flour contains a large proportion of the hull that adheres to the testa layer of the groats and is difficult to be removed in industrial processing. Fortunat...

journal_title：Genes

authors： Zhang L,Ma M,Liu L

更新日期：2020-04-23 00:00:00

abstract：:In addition to its wide geographical distribution, osteoglossiform fishes represent one of the most ancient freshwater teleost lineages; making it an important group for systematic and evolutionary studies. These fishes had a Gondwanan origin and their past distribution may have contributed to the diversity present in...

journal_title：Genes

authors： Barby FF,Ráb P,Lavoué S,Ezaz T,Bertollo LAC,Kilian A,Maruyama SR,Aguiar de Oliveira E,Artoni RF,Santos MH,Ilesanmi Jegede O,Hatanaka T,Tanomtong A,Liehr T,Cioffi MB

更新日期：2018-06-19 00:00:00

abstract：:The filamenting temperature-sensitive Z proteins (FtsZs) play an important role in plastid division. In this study, three FtsZ genes were isolated from the cassava genome, and named MeFtsZ1, MeFtsZ2-1, and MeFtsZ2-2, respectively. Based on phylogeny, the MeFtsZs were classified into two groups (FtsZ1 and FtsZ2). MeFts...

journal_title：Genes

authors： Geng MT,Min Y,Yao Y,Chen X,Fan J,Yuan S,Wang L,Sun C,Zhang F,Shang L,Wang YL,Li RM,Fu SP,Duan RJ,Liu J,Hu XW,Guo JC

更新日期：2017-12-15 00:00:00

abstract：:Testis cords are the embryonic precursors of the seminiferous tubules. Development of testis cords is a key event during embryonic testicular morphogenesis and is regulated by multiple signaling molecules produced by Sertoli cells. However, the exact nature and the cascade of molecular events underlying testis cord de...

journal_title：Genes

authors： Zheng W,Nazish J,Wahab F,Khan R,Jiang X,Shi Q

更新日期：2019-11-26 00:00:00