当前位置： SCI文献检索 > EXPERIMENTAL PARASITOLOGY期刊下所有文献 > Nematospiroides dubius: influence of adjuvants on immunity in mice vaccinated with antigens isolated by affinity chromatography from adult worms.

Nematospiroides dubius: influence of adjuvants on immunity in mice vaccinated with antigens isolated by affinity chromatography from adult worms.

Abstract：

:Five adjuvants were examined for their ability to potentiate the immune response of mice to soluble antigens from adult Nematospiroides dubius prepared by affinity chromatography against antibodies from repeatedly infected mice as ligands (IMIgAg). Immunized mice were better protected against N. dubius by IMIgAg injected intraperitoneally with either pertussigen (75%) or aluminium hydroxide (Alum) (67%) as adjuvants than with Freud's complete (54%) or incomplete adjuvants (31%). Protection was correlated with elevated specific antibody values and with cellular responses. Quil A was toxic to recipient mice at the concentration used. Alum may be a more practical adjuvant than pertussigen, which may activate protective immunity only in specific recipient genotypes and oil-based adjuvants which appear to be less efficient, to vaccinate mice with soluble parasite antigens.

journal_name

Exp Parasitol

journal_title

Experimental parasitology

authors

Monroy FG,Adams JH,Dobson C,East IJ

doi

10.1016/0014-4894(89)90009-x

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

67-73

issue

1

eissn

0014-4894

issn

1090-2449

pii

0014-4894(89)90009-X

journal_volume

68

pub_type

杂志文章

相关文献

EXPERIMENTAL PARASITOLOGY文献大全
  • Steinernema carpocapsae DD136: metabolites limit the non-self adhesion responses of haemocytes of two lepidopteran larvae, Galleria mellonella (F. Pyralidae) and Malacosoma disstria (F. Lasiocampidae).

    abstract：:Live adult and juvenile entomopathogenic Steinernema carpocapsae DD136 (P. Nematoda) were not subjected to adhesion by haemocytes of lepidopteran insect larvae of Galleria mellonella or Malacosoma disstriain vitro or in vivo. In vitro freeze-killed nematodes exhibited haemocyte attachment, the intensity increasing wit...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2008.07.001

    authors： Walter TN,Dunphy GB,Mandato CA

    更新日期：2008-10-01 00:00:00

  • Onchocerca volvulus: comparative analysis of antibody responses to recombinant antigens in two animal models of onchocerciasis.

    abstract：:Experimental infections of chimpanzees with Onchocerca volvulus and cattle with Onchocerca ochengi provide model systems for research in human onchocerciasis. These infections share many similarities from the standpoint of parasite biology, but little is known about the comparability of immune responses in the two sys...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.2000.4487

    authors： Graham SP,Lustigman S,Trees AJ,Bianco AE

    更新日期：2000-03-01 00:00:00

  • Schistosoma mansoni: L-glutamate-induced contractions in isolated muscle fibers; evidence for a glutamate transporter.

    abstract：:Schistosoma mansoni muscle fibers contract in response to L-glutamate in a dose-dependent manner (10(-6)-10(-3) M). L-aspartate and D-aspartate are likewise effective in eliciting contraction of the fibers. Mammalian glutamate receptor agonists produce little or no contraction at concentrations as high as 1 mM. In add...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1996.0129

    authors： Miller CL,Day TA,Bennett JL,Pax RA

    更新日期：1996-12-01 00:00:00

  • A new Leishmania hypothetical protein can be used for accurate serodiagnosis of canine and human visceral leishmaniasis and as a potential prognostic marker for human disease.

    abstract：:Distinct antigens have been evaluated with diagnostic purpose for canine and human visceral leishmaniasis (VL), and variable sensitivity and specificity values have been obtained in the assays. In the present study, a Leishmania infantum hypothetical protein called LiHyG, which was identified in an immunoproteomics st...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2020.107941

    authors： Machado AS,Ramos FF,Santos TTO,Costa LE,Ludolf F,Lage DP,Bandeira RS,Tavares GSV,Oliveira-da-Silva JA,Steiner BT,Chaves AT,Oliveira JS,Chávez-Fumagalli MA,de Magalhães-Soares DF,Silveira JAG,Duarte MC,Machado-de-Ávila RA

    更新日期：2020-09-01 00:00:00

  • Molecular identification of Vermamoeba vermiformis from freshwater fish in lake Taal, Philippines.

    abstract：:Free Living Amoebae (FLA) are considered ubiquitous. FLAs may infect various biological organisms which act as reservoir hosts. Infected freshwater fishes can pose a public health concern due to possible human consumption. This study aims to identify possible pathogenic FLAs present in freshwater fishes. Seventy five ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2017.09.009

    authors： Milanez GD,Masangkay FR,Thomas RC,Ordona MOGO,Bernales GQ,Corpuz VCM,Fortes HSV,Garcia CMS,Nicolas LC,Nissapatorn V

    更新日期：2017-12-01 00:00:00

  • Identification of α-11 giardin as a flagellar and surface component of Giardia lamblia.

    abstract：:Giardia lamblia is a protozoan pathogen with distinct cytoskeletal structures, including median bodies and eight flagella. In this study, we examined components comprising G. lamblia flagella. Crude flagellar extracts were prepared from G. lamblia trophozoites, and analyzed by two-dimensional (2-D) gel electrophoresis...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2013.07.010

    authors： Kim J,Lee HY,Lee MA,Yong TS,Lee KH,Park SJ

    更新日期：2013-10-01 00:00:00

  • Neospora caninum: comparative gene expression profiling of Neospora caninum wild type and a temperature sensitive clone.

    abstract：:To understand the genetic basis of virulence, gene expression profiles of a temperature-sensitive clone (NCts-8, relatively avirulent) and its wild type (NC-1) of Neospora caninum were characterized and compared using a high-density microarray with approximately 63,000 distinct oligonucleotides. This microarray consis...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2011.09.007

    authors： Li RW,Tuo W

    更新日期：2011-12-01 00:00:00

  • Schistosoma mansoni: influence of infection on mouse behavior.

    abstract：:Schistosoma mansoni infection in humans and animals induces abnormal neurobehavioral responses following granuloma formation. In mice, granulomas in the liver are observed 8 weeks after infection, while after 15-20 weeks, the presence of eggs and granulomas in the brain has been reported. In this study, outbred CD-1 f...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1996.0047

    authors： Fiore M,Moroni R,Alleva E,Aloe L

    更新日期：1996-06-01 00:00:00

  • Leishmania amazonensis: specific labeling of amastigote cysteine proteinases by radioiodinated N-benzyloxycarbonyl-tyrosyl-alanyl diazomethane.

    abstract：:Living Leishmania amazonensis amastigotes were incubated with radioiodinated N-benzyloxycarbonyl-L-tyrosyl-L-alanyl diazomethane (Z-Tyr-AlaCHN2), an irreversible inhibitor of mammalian cathepsins B and L. Parasite lysates were subjected to electrophoresis in gelatin-containing sodium dodecyl sulfate-acrylamide gels to...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(91)90066-6

    authors： Alfieri SC,Pral EM,Shaw E,Ramazeilles C,Rabinovitch M

    更新日期：1991-11-01 00:00:00

  • Heterodera glycines: density-based gradient separation of eggs.

    abstract：:An efficient technique was developed for separating early and late stages of embryonic development in eggs of Heterodera glycines. This technique takes advantage of density changes that occur during embryogenesis in the developing embryo and egg to partition the egg within a sucrose step gradient. Sorted samples of eg...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2003.12.007

    authors： Burgwyn B,Cook RL,Bolla RI

    更新日期：2003-11-01 00:00:00

  • Trypanosoma cruzi: fusogenic ability of membranes from cultured epimastigotes in interaction with human syncytiotrophoblast.

    abstract：:Trypanosoma cruzi epimastigotes cultured in vitro were disrupted by successive freezing and thawing and subsequent sonication. The total homogenate was fractionated by differential centrifugation to obtain an enriched plasma membrane fraction. The proteins of subcellular parasite fractions were labeled with 131I and t...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(83)90059-0

    authors： Calderon RO,de Fabro SP

    更新日期：1983-10-01 00:00:00

  • MicroRNA expression profiling of dibenzalacetone (DBA) treated intracellular amastigotes of Leishmania donovani.

    abstract：BACKGROUND:Among different leishmanial infections, visceral leishmaniasis (VL) if not treated is the most severe form with high mortality rates. In India, it is caused by the protozoan parasite Leishmania donovani. The therapy of visceral leishmaniasis is limited due to high toxicity, resistance to existing drugs and i...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2018.07.018

    authors： Singh N,Chauhan IS

    更新日期：2018-10-01 00:00:00

  • Expression profile and subcellular localization of HslV, the proteasome related protease from Trypanosoma cruzi.

    abstract：:Trypanosoma cruzi is a rare example of an eukaryote that has genes for two threonine proteases: HslVU complex and 20S proteasome. HslVU is an ATP-dependent protease consisting of two multimeric components: the HslU ATPase and the HslV peptidase. In this study, we expressed and obtained specific antibodies to HslU and ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2011.10.011

    authors： Barboza NR,Cardoso J,de Paula Lima CV,Soares MJ,Gradia DF,Hangai NS,Bahia MT,de Lana M,Krieger MA,Guerra de Sá R

    更新日期：2012-02-01 00:00:00

  • Trypanosoma brucei: two-dimensional gel analysis of the major glycosomal proteins during the life cycle.

    abstract：:Kinetoplastid organisms possess a unique organelle, the glycosome, which compartmentalizes the Embden-Meyerhof segment of glycolysis and several other metabolic pathways. In Trypanosoma brucei many of the enzyme activities localized to the glycosome are stage regulated. Two-dimensional gel analysis was used to examine...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(90)90109-p

    authors： Parsons M,Nielsen B

    更新日期：1990-04-01 00:00:00

  • Plasmodium berghei: partial purification and characterization of the mitochondrial cytochrome c oxidase.

    abstract：:Mitochondria from a rodent malarial parasite (Plasmodium berghei) were successfully purified by differential centrifugation and 22% Percoll density gradient separation. The purified mitochondria from the erythrocytic stages of the parasite had a density of 1.05 and were found to be heterogeneous by transmission electr...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1993.1070

    authors： Krungkrai J,Krungkrai SR,Bhumiratana A

    更新日期：1993-09-01 00:00:00

  • Diversity of Sarcocystis spp shed by opossums in Brazil inferred with phylogenetic analysis of DNA coding ITS1, cytochrome B, and surface antigens.

    abstract：:Although few species of Sarcocystis are known to use marsupials of the genus Didelphis as definitive host, an extensive diversity of alleles of surface antigen genes (sag2, sag3, and sag4) has been described in samples of didelphid opossums in Brazil. In this work, we studied 25 samples of Sarcocystis derived from gas...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2016.02.008

    authors： Valadas SY,da Silva JI,Lopes EG,Keid LB,Zwarg T,de Oliveira AS,Sanches TC,Joppert AM,Pena HF,Oliveira TM,Ferreira HL,Soares RM

    更新日期：2016-05-01 00:00:00

  • Validation of cell-free culture using scanning electron microscopy (SEM) and gene expression studies.

    abstract：:A cell-free culture system for Cryptosporidium parvum was analysed using scanning electron microscopy (SEM) to characterise life cycle stages and compare gene expression in cell-free culture and cell culture using HCT-8 cells. Cryptosporidium parvum samples were harvested at 2 h, 8 h, 14 h, 26 h, 50 h, 74 h, 98 h, 122...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2015.03.002

    authors： Yang R,Elankumaran Y,Hijjawi N,Ryan U

    更新日期：2015-06-01 00:00:00

  • Glycosidases in Leishmania and their importance for Leishmania in phlebotomine sandflies with special reference to purification and characterization of a sucrase.

    abstract：:Culture forms of Leishmania (Leishmania) amazonensis (IFLA/BR/67/PH8) produce an extracellular enzyme that hydrolyzes sucrose molecules into their component monosaccharides. This is important because phlebotomine sand flies, the invertebrate hosts of Leishmania, ingest plant sap or aphid and coccid honeydew rich in su...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1996.0055

    authors： Gontijo NF,Melo MN,Riani EB,Almeida-Silva S,Mares-Guia ML

    更新日期：1996-06-01 00:00:00

  • Amblyomma americanum: requirement for host Fc receptors in antibody-mediated acquired immune resistance to ticks.

    abstract：:Guinea pig recipients of anti-tick immune serum or immune peritoneal exudate cells expressed 25 and 30% tick rejection, respectively, when challenged with Amblyomma americanum larval ticks. Previous studies have shown that IgG1 antibodies are responsible for the ability of immune serum to transfer resistance to ticks ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(85)90079-7

    authors： Brown SJ,Askenase PW

    更新日期：1985-04-01 00:00:00

  • Giardia lamblia: the roles of bile, lactic acid, and pH in the completion of the life cycle in vitro.

    abstract：:Large numbers (10(4) to greater than 10(5)/ml) of Type I water-resistant Giardia lamblia cysts were produced in vitro under conditions that are characteristic of the human intestinal lumen. We define Type I cyst morphology as oval shaped, smooth, and refractile, with cyst wall, axostyle, and median body visible in rel...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(89)90185-9

    authors： Gillin FD,Boucher SE,Rossi SS,Reiner DS

    更新日期：1989-08-01 00:00:00

  • An experimental model of ameboma in guinea pig.

    abstract：:Among the wide variety of clinicopathological manifestations of intestinal amebiasis, amebomas occur rarely and their pathogenesis is not well understood. When cholesterol-fed, 2- to 4-week-old guinea pigs were infected intracecally with a virulent, monoaxenic strain of Entamoeba histolytica, gross and histologically ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(92)90151-y

    authors： Bhatti HS,Bhushnurmath S,Mahajan RC,Ganguly NK,Sehgal R

    更新日期：1992-05-01 00:00:00

  • Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi.

    abstract：:Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J mice succumbed to infect...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2004.07.011

    authors： Hernandez-Valladares M,Naessens J,Nagda S,Musoke AJ,Rihet P,Ole-Moiyoi OK,Iraqi FA

    更新日期：2004-11-01 00:00:00

  • Acanthamoeba spp.: in vitro effects of clinical isolates on murine macrophages, osteosarcoma and HeLa cells.

    abstract：:Three different cell lines (murine macrophages, HeLa and osteosarcoma cells) were assayed in order to check for the manifestation of the cytopathic effects of three strains of Acanthamoeba recently isolated in our laboratory from contact lens cases: CLC-16, CLC-41.r and CLC-51-l. Adhesion and cytotoxicity assays were ...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2009.10.011

    authors： Martín-Navarro CM,Lorenzo-Morales J,Machín RP,López-Arencibia A,Valladares B,Piñero JE

    更新日期：2010-09-01 00:00:00

  • Brain endothelial cells increase the proliferation of Plasmodium falciparum through production of soluble factors.

    abstract：:We here describe the novel finding that brain endothelial cells in vitro can stimulate the growth of Plasmodium falciparum through the production of low molecular weight growth factors. By using a conditioned medium approach, we show that the brain endothelial cells continued to release these factors over time. If thi...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2014.07.002

    authors： Khaw LT,Ball HJ,Mitchell AJ,Grau GE,Stocker R,Golenser J,Hunt NH

    更新日期：2014-10-01 00:00:00

  • Trypanosoma musculi: characterization of the T-lymphocyte dependency of immunity by selective immunomodulation of the mouse, Mus musculus.

    abstract：:Trypanosoma musculi is a hemoflagellate parasite producing a characteristic course of infection in the mouse, terminating in elimination of the parasite from the vascular system with permanent immunity to reinfection. While this elimination is known to require functional T lymphocytes, the role of these cells has rema...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/0014-4894(88)90013-6

    authors： House RV,Dean JH

    更新日期：1988-10-01 00:00:00

  • Therapeutic effects of Echinococcus granulosus cystic fluid on allergic airway inflammation.

    abstract：:Previous studies showed that Echinococcus granulosus infection reduces allergic airway inflammation in experimentally infected hosts and the cystic fluid of E. granulosus is known to activate regulatory T (CD4+CD25+Foxp3+T, Treg) cells. To evaluate the effects of cystic fluid of E. granulosus on allergic airway inflam...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2019.02.003

    authors： Kim HJ,Kang SA,Yong TS,Shin MH,Lee KJ,Park GM,Suvonkulov U,Yu HS

    更新日期：2019-03-01 00:00:00

  • Trypanosoma cruzi: the Tc-85 surface glycoprotein shed by trypomastigotes bears a modified glycosylphosphatidylinositol anchor.

    abstract：:Tc-85, an 85-kDa surface glycoprotein specific for the trypomastigote stage of Trypanosoma cruzi, has been implicated in the invasion of host cells by the parasite. Radioactive palmitic acid was incorporated into Tc-85 immunoprecipitated from the culture medium with the H1A10 monoclonal antibody, suggesting that shedd...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1006/expr.1996.0036

    authors： Abuin G,Couto AS,de Lederkremer RM,Casal OL,Galli C,Colli W,Alves MJ

    更新日期：1996-04-01 00:00:00

  • Behavioral changes in host foraging: Experiments with Clinostomum (Trematoda, Digenea) parasitizing Loricariichthys platymetopon (Loricariidae).

    abstract：:Complex life cycle parasites can manipulate the behavior of intermediate hosts in order to reduce their fitness and increase the chance of completing life cycle. In order to understand the effects of the trematode parasites of the genus Clinostomum on host fish Loricariichthys platymetopon, a filmed experiment was car...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2020.107916

    authors： Nicola DN,Affonso IP,Takemoto RM

    更新日期：2020-09-01 00:00:00

  • Effects of IFN-γ, TNF-α, IL-10 and TGF-β on Neospora caninum infection in rat glial cells.

    abstract：:Neospora caninum causes abortion in cattle and neurological disorders in dogs. The immunological response to this parasite has been described as predominantly of the Th1 type. However, infected primary glial cell cultures release IL-10 and IL-6 but not IFN-γ. This suggests a rather protective response of the glia to a...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2012.11.016

    authors： Jesus EE,Pinheiro AM,Santos AB,Freire SM,Tardy MB,El-Bachá RS,Costa SL,Costa MF

    更新日期：2013-03-01 00:00:00

  • Toxoplasma gondii: effects of Artemisia annua L. on susceptibility to infection in experimental models in vitro and in vivo.

    abstract：:Considering that the treatment for toxoplasmosis is based on drugs that show limited efficacy due to their substantial side effects, the purpose of the present study was to evaluate the effects of Artemisia annua on in vitro and in vivo Toxoplasma gondii infection. A. annua infusion was prepared from dried herb and te...

    journal_title：Experimental parasitology

    pub_type： 杂志文章

    doi：10.1016/j.exppara.2009.04.010

    authors： de Oliveira TC,Silva DA,Rostkowska C,Béla SR,Ferro EA,Magalhães PM,Mineo JR

    更新日期：2009-07-01 00:00:00