Mechanisms of Cardioprotection of Halogenated Agents During Extracorporeal Circulation in Cardiac Surgery.

abstract：BACKGROUND:The most common complications of chronic kidney disease (CKD) are hypertension and cardiovascular (CV) disorders. Renalase is produced and released by the kidney and also cardiomyocytes. Renalase deficiency was claimed to be responsible for hypertension and CV complication in CKD. There are contradictory dat...

journal_title：Current vascular pharmacology

authors： Malyszko J,Koc-Zorawska E,Zorawski M,Kozminski P,Zbroch E,Rysz J,Banach M,Malyszko JS

更新日期：2015-01-01 00:00:00

abstract：:Cardiovascular failure in sepsis involves a combination of hypovolemia, decreased vascular tone, myocardial depression and microcirculatory alterations. Fluids represent the first line therapeutic intervention, with controversy regarding the type of fluid. Recent data indicate that albumin is safe and might even be be...

journal_title：Current vascular pharmacology

authors： De Backer D,Scolletta S

更新日期：2013-03-01 00:00:00

abstract：:Obesity and Gestational Diabetes Mellitus (GDM) are the most frequent pathologies affecting mothers and offspring during pregnancy. Both conditions have shown a sustained increase in their prevalence in recent years, and they worsen the outcome of pregnancy and the long-term health of mothers. Obesity increases the ri...

journal_title：Current vascular pharmacology

authors： Poblete JA,Olmos P

更新日期：2021-01-01 00:00:00

abstract：:Non-fasting triglycerides are measured at any time within up to 8 h (14 h) after any normal meal, while postprandial triglycerides are measured at a fixed time point within up to 8 h (14 h) of a standardised fat tolerance test. The simplest possible way of evaluating remnant cholesterol is non-fasting/postprandial tot...

journal_title：Current vascular pharmacology

authors： Nordestgaard BG,Freiberg JJ

更新日期：2011-05-01 00:00:00

abstract：:Chronic kidney disease (CKD) is associated with high cardiovascular morbidity and mortality. The available data suggest that efforts to reduce mortality in the CKD population should be focused on treatment and prevention of, among others, coronary artery disease and congestive heart failure. Accelerated atherosclerosi...

journal_title：Current vascular pharmacology

authors： Franczyk-Skóra B,Gluba A,Banach M,Rozentryt P,Poloński L,Rysz J

更新日期：2013-09-01 00:00:00

abstract：:This paper provides an overview of the pathogenesis, presentation and diagnosis of clopidogrel hypersensitivity. The majority of clopidogrel hypersensitivity cases are due to a T cell mediated Gell and Coombs Type IV reaction. History, histology, and patch testing have shown consistency with a T cell mediated mechanis...

journal_title：Current vascular pharmacology

authors： Ford MK,Cohn JR

更新日期：2019-01-01 00:00:00

abstract：:Loss of normal endothelial function and bioactivity of nitric oxide (NO), associated with increased production of reactive oxygen species (ROS), are characteristics of cardiovascular disease states. There is good experimental evidence that these abnormalities are causally related to cardiovascular disease pathogeneses...

journal_title：Current vascular pharmacology

authors： Channon KM

更新日期：2012-11-01 00:00:00

abstract：:Platelet adhesion on vascular wall is the first step following vascular injury. Differential platelet secretion supports angiogenesis and vascular homeostasis. Progenitor cells are pluripotent cells responsible for tissue regeneration and wound healing. Upon ischemia bone marrow-derived progenitor cells are mobilized ...

journal_title：Current vascular pharmacology

authors： Sopova K,Tatsidou P,Stellos K

更新日期：2012-09-01 00:00:00

abstract：:Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of t...

journal_title：Current vascular pharmacology

authors： Haidara MA,Assiri AS,Yassin HZ,Ammar HI,Obradovic MM,Isenovic ER

更新日期：2015-01-01 00:00:00

abstract：:Central arterial systolic blood pressure is a very important factor in the pathophysiology of cardiovascular diseases. Central arterial pressure is a better predictor of cardiovascular risk than peripheral brachial blood pressure. Measurement of central blood pressure is useful for a diagnosis of spurious systolic hyp...

journal_title：Current vascular pharmacology

authors： Stepień M,Banach M,Jankowski P,Rysz J

更新日期：2010-11-01 00:00:00

abstract：:The aim of this review is to present, critically appraise and qualitatively synthesize current evidence on the risk of type 2 diabetes mellitus (T2DM) development during menopause, the management of climacteric symptoms in women with T2DM and the management of T2DM in postmenopausal women. Menopause represents the end...

journal_title：Current vascular pharmacology

authors： Paschou SA,Anagnostis P,Pavlou DI,Vryonidou A,Goulis DG,Lambrinoudaki I

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Current vascular pharmacology

authors： Guerrero Orriach JL,Ramirez-Fernandez A

更新日期：2019-01-01 00:00:00

abstract：:The incidence of cardiovascular disease is low in healthy premenopausal women and increases with age especially after the menopause; this difference has been attributed to the loss of endogenous estrogen. Atherosclerosis is a chronic inflammatory condition of the vascular wall that may result in an acute clinical even...

journal_title：Current vascular pharmacology

authors： Bechlioulis A,Naka KK,Calis KA,Makrigiannakis A,Michalis L,Kalantaridou SN

更新日期：2010-03-01 00:00:00

abstract：INTRODUCTION:Chlamydia pneumoniae was the first pathogen linked with carotid atherosclerotic changes and plaque rupture. Currently, other common pathogens are also under investigation as potential contributors. METHODS:A systematic review of PubMed and Scopus databases was performed. Studies evaluating the infectious ...

journal_title：Current vascular pharmacology

authors： Makris GC,Makris MC,Wilmot VV,Geroulakos G,Falagas ME

更新日期：2010-11-01 00:00:00

abstract：:Immunosuppressive drugs (ISDs) have a major impact on the development and progression of cardiac allograft vasculopathy (CAV), the main cause of cardiac allograft loss and a leading cause of death beyond the 1st post-transplant year. The influence of ISDs on the development and progression of CAV is complex. In spite ...

journal_title：Current vascular pharmacology

authors： Dandel M,Hetzer R

更新日期：2010-09-01 00:00:00

abstract：:In the last decade there have been considerable advances in the understanding of the pathophysiology of malignant ventricular tachyarrhythmias (VA) and Sudden Cardiac Death (SCD). Over 80% of SCD occurs in patients with organic heart disease. However, approximately 10-15% of SCD occurs in the presence of structurally ...

journal_title：Current vascular pharmacology

authors： El-Sherif N,Pedalino R,Himel H 4th

更新日期：2009-07-01 00:00:00

abstract：:A considerable amount of data supports a 1.8-7.4-fold increased mortality associated with Cushing's syndrome (CS). This is attributed to a high occurrence of several cardiovascular disease (CVD) risk factors in CS [e.g. adiposity, arterial hypertension (AHT), dyslipidaemia and type 2 diabetes mellitus (T2DM)]. Therefo...

journal_title：Current vascular pharmacology

authors： Koracevic G,Stojkovic M,Lovic D,Pavlovic M,Kostic T,Kutlesic M,Micic S,Koracevic M,Djordjevic M

更新日期：2020-01-01 00:00:00

abstract：:Statins are beneficial both in the primary and secondary prevention of atherosclerotic vascular disease and acute events in a broad spectrum of patient subgroups. However, the observed clinical benefit with statin therapy is much greater than expected through the reduction of cholesterol levels alone. Clinical and exp...

journal_title：Current vascular pharmacology

authors： Yildirir A,Müderrisoglu H

更新日期：2004-10-01 00:00:00

abstract：:There is growing evidence that Rho-kinase contributes to cardiovascular disease, which has made Rho-kinase a target for the treatment of human diseases. To date, the only Rho-kinase inhibitor employed clinically in humans is fasudil, which has been used for the prevention of cerebral vasospasm and subsequent ischemic ...

journal_title：Current vascular pharmacology

authors： Satoh S,Ikegaki I,Kawasaki K,Asano T,Shibuya M

更新日期：2014-01-01 00:00:00

abstract：:Aldosterone, a steroid hormone with mineralocorticoid activity, is far more than merely a salt-and-water hormone. Aldosterone has a number of non-classical, mineralocorticoid receptor (MR)-mediated actions, including tissue remodeling, modulation of vascular tone and stimulating inflammation and fibrosis, which may fu...

journal_title：Current vascular pharmacology

authors： Waanders F,de Vries LV,van Goor H,Hillebrands JL,Laverman GD,Bakker SJ,Navis G

更新日期：2011-09-01 00:00:00

abstract：:In end-stage renal disease patients, the leading causes of mortality are of cardiovascular (CV) origin. The underlying mechanisms are complex, given that sudden heart failure is more common than acute myocardial infarction. A contributing role of oxidative stress is postulated, which is increased even at early stages ...

journal_title：Current vascular pharmacology

authors： Roumeliotis S,Roumeliotis A,Gorny X,Mertens PR

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Obstructive Sleep Apnoea (OSA) constitutes the most prevalent form of abnormal respiratory control during sleep in adults. Evidence linked OSA to cardiovascular disease, and the role of OSA in abnormal Blood Pressure (BP) control has been extensively studied. Although longitudinal trials suggest a causativ...

journal_title：Current vascular pharmacology

authors： Wolf J,Narkiewicz K

更新日期：2017-01-01 00:00:00

abstract：:Initially, the progression of chronic venous insufficiency is related to venous hypertension. The earliest complaints or symptoms, as well as vessel wall deterioration, valve restructuring, and, eventually, varicose veins, result not only from elevation of pressure, but also from a cascade of biochemical events relate...

journal_title：Current vascular pharmacology

authors： Katsenis K

更新日期：2005-01-01 00:00:00

abstract：:Prostaglandins (PGs) belong to the family of prostanoids together with thromboxanes and are produced mainly from arachadonic acid by the enzyme cyclooxygenase. PGs are known to stimulate platelet aggregation, mediate inflammation and edema, play a role in bone metabolism and in biological adaptation of connective tiss...

journal_title：Current vascular pharmacology

authors： Boushel R,Langberg H,Risum N,Kjaer M

更新日期：2004-04-01 00:00:00

abstract：:The "pleiotropic" effects of statins have been the centre of a considerable research activity. Among the numerous experimental and clinical studies of this field, some focused on the effects of statins on blood pressure (BP), while others reported data on BP together with other parameters. Some of the animal or human ...

journal_title：Current vascular pharmacology

authors： Sarafidis PA,Kanaki AI,Lasaridis AN

更新日期：2007-04-01 00:00:00

abstract：:Several cellular and molecular mechanisms have been implicated in the development of myocardial dysfunction and low cardiac output in pediatric patients undergoing heart surgery. Ischemia- reperfusion injury with alterations in calcium homeostasis as well as mitochondrial function has been strongly related to myocyte ...

journal_title：Current vascular pharmacology

authors： Bautista-Hernandez V,Karamanlidis G,McCully JD,Del Nido PJ

更新日期：2016-01-01 00:00:00

abstract：:Hypercoagulability is widely associated with sepsis, inflammation, diabetes, cancers, aging, and many pathological conditions, resulting in life-threatening disseminated intravascular coagulation (DIC), venous thrombosis, thromboembolism, cardiovascular complications, or even deadly multiple organ failure. Relieving c...

journal_title：Current vascular pharmacology

authors： Chu AJ

更新日期：2004-07-01 00:00:00

abstract：:Epidemiological evidence supports a reduced prevalence of Thoracic Aortic Aneurysm (TAA) and Abdominal Aortic Aneurysm (AAA) in patients with Diabetes (DM). The mechanisms underlying this negative association are unknown. Some studies support that hyperglycemia has effects on the Extracellular Matrix (ECM), resulting ...

journal_title：Current vascular pharmacology

authors： Krizhanovskii C,Franco-Cereceda A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the general population. The disease ranges from simple steatosis, to non-alcoholic steatohepatitis (NASH), cirrhosis and even hepatocellular carcinoma. Several drugs are used in daily clinical practice to manage the disease. However, dat...

journal_title：Current vascular pharmacology

authors： Imprialos K,Stavropoulos K,Bouloukou S,Kerpiniotis G,Karagiannis A,Doumas M

更新日期：2018-01-01 00:00:00

abstract：:Aspirin plays a pivotal role in the management of patients with Coronary Artery Disease (CAD) with well-recognised benefits of reducing recurrent myocardial infarction and minimising the risk of stent thrombosis for those undergoing Percutaneous Coronary Intervention (PCI). Dual antiplatelet therapy is mandated for pa...

journal_title：Current vascular pharmacology

authors： Kassimis G,Raina T,Alexopoulos D

更新日期：2019-01-01 00:00:00