Abstract:
OBJECTIVES:To determine, in conjunction with a wider investigation, whether 11 genetic variants in the vicinity of vitamin D, collagen and Wnt signalling pathways were associated with stress fracture injury in the Stress Fracture Elite Athlete (SFEA) cohort. DESIGN:Genotype-phenotype association study. METHODS:Self-reported stress fracture history and demographic data were recorded in 518 elite athletes, 449 male and 69 female (mean age 24.2±5.5 years) from the SFEA cohort. Elite athletes were assigned to two groups based on history of stress fracture injury. Data were analysed for the whole cohort and sub-stratified in to male only and multiple stress fracture cases. Genotype was determined using a proprietary fluorescence-based competitive allele-specific polymerase chain reaction assay. RESULTS:SOST SNP rs1877632 and VDR SNPs rs10735810 and rs731236 were associated with stress fracture (p<0.05). In the whole cohort, rs1877632 heterozygotes and homozygotes of the rare allele combined made up 59% of stress fracture sufferers in comparison to 46% in the non-stress fracture group (p=0.05). In the multiple stress fracture cohort, homozygotes of the rare allele of rs10735810 and rs731236 showed an association with stress fracture when compared to those homozygotes for the common allele combined with heterozygotes (p=0.03; p=0.01). No significant associations were shown in the other SNPs analysed (p>0.05). CONCLUSIONS:These data suggest an important role for SOST SNP rs1877632 and VDR SNPs rs10735810 and rs731236 in the pathophysiology of stress fracture. This might be due to the role of the SNPs in the regulation of bone remodelling and adaptation to mechanical loading, with potential implications for the prevention and treatment of stress fracture injuries.
journal_name
J Sci Med Sportjournal_title
Journal of science and medicine in sportauthors
Varley I,Hughes DC,Greeves JP,Stellingwerff T,Ranson C,Fraser WD,Sale Cdoi
10.1016/j.jsams.2017.10.038subject
Has Abstractpub_date
2018-06-01 00:00:00pages
564-568issue
6eissn
1440-2440issn
1878-1861pii
S1440-2440(17)31751-6journal_volume
21pub_type
杂志文章abstract:OBJECTIVES:To investigate the effect of Kinesio Taping (KT) applied over the biceps brachii on maximal isokinetic elbow torque. DESIGN:This study followed a single-blinded, placebo controlled, repeated measures design. METHODS:Isokinetic eccentric and concentric elbow peak torques were evaluated without taping (NT), ...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jsams.2012.06.003
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:The health benefits from participation in half-marathon is challenged by a yearly running-related injury (RRI) incidence proportion exceeding 30%. Research in injury etiology is needed to successfully prevent injuries. The body's load capacity is believed to play an essential role for injury development. The...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2018.08.014
更新日期:2019-03-01 00:00:00
abstract::Despite frequent media accounts of drownings in the United Arab Emirates, little was known about the epidemiology and prevention of such incidents. The research objective was to assess newspapers as a national source on incidence, activities, and risk factors for drowning in this high-income media-rich developing coun...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2007.08.016
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:To develop a valid and reliable video-based decision-making test to examine and monitor the decision-making performance of Australian football umpires. DESIGN:Validation assessments with test re-test reliability. METHODS:A video-based decision-making test was developed from a pool of 156 video-based decisi...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2013.08.001
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVES:Current best evidence has reported that therapeutic exercise programs that are designed to treat patellofemoral pain (PFP) should include both hip and knee specific exercises. The purpose of this review was to (1) examine the quality/comprehensiveness of exercise reporting in this field; (2) quantify the ext...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,评审
doi:10.1016/j.jsams.2020.09.001
更新日期:2020-09-10 00:00:00
abstract::Children's physical activity (PA) patterns change from day to day. This intra-individual variability affects precision when measuring key physical activity and sedentary behaviour variables. This paper discusses strategies used to reduce the random error associated with intra-individual variability and demonstrates th...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2008.09.009
更新日期:2009-09-01 00:00:00
abstract::The terminology used for monitoring and promoting physical activity and exercise among health and fitness professionals varies considerably. There is a large array of descriptor terms reported in the literature and used in day-to-day practice and this inconsistency can be confusing for clients and practitioners alike....
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,评审
doi:10.1016/j.jsams.2009.09.008
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVES:Professional ballet dancers may have hip bony morphology that predisposes them to cartilage or labral injury. However, the relationship between bony morphology and pathology has not been investigated in ballet. This study investigates associations between bony morphology, chondrolabral defects and hip pain i...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2018.02.014
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVES:To determine the utility of the King-Devick (K-D) test in identifying sports-related concussion in semi-professional rugby players. DESIGN:Descriptive cohort study. METHODS:176 male players were recruited from a semi-professional rugby union competition in New Zealand (NZ). Baseline K-D scores were obtaine...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2017.02.002
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:This study presents a comprehensive examination of the Sport Drug Control Model via survey data of elite Australian athletes. DESIGN:A cross-sectional nationwide mail survey. METHODS:A mail survey of 1237 elite Australian athletes was conducted. Structural equation modelling was employed to test the model....
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2013.10.249
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:Participants of ultramarathon events experience a complex interaction of psychophysiological stressors. Therefore, the purpose of this study was to investigate the role of trait emotional intelligence (trait EI) on mood states and serum cortisol responses to a 80.5km treadmill ultramarathon. DESIGN:Twelve p...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2019.02.008
更新日期:2019-07-01 00:00:00
abstract::This study examined the relationship between the bowling workload of first-class fast bowlers and injury with the aim of identifying a "safe" fast bowling workload threshold. Twelve male fast bowlers (mean age 25 years) from an Australian state cricket squad were observed for the 1999--2000 cricket season. Workload wa...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/s1440-2440(04)80014-8
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:To compare catastrophic injury rates between the 14 South African Provincial Rugby Unions. DESIGN:A prospective, population-based study conducted among all South African Unions between 2008-2014. METHODS:Player numbers in each Union were obtained from South African Rugby's 2013 Census. Catastrophic injurie...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2017.01.232
更新日期:2017-07-01 00:00:00
abstract::The epidemiological rationale for a focus on physical activity (PA) among Aboriginal and Torres Strait Islander (ATSI) people is compelling. PA programs have significant potential to benefit ATSI people and their communities through their contribution to reducing chronic disease, improving physical and mental health a...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,评审
doi:10.1016/s1440-2440(04)80276-7
更新日期:2004-04-01 00:00:00
abstract::A paucity of empirical research exists into surf lifesaving competition from which coaches and athletes may formulate training and recovery strategies. Seventeen (male=9; female=8) high-performance surf lifesavers (21.2+/-3.9 years) contested multiple rounds of team and individual events at a 2-day surf lifesaving com...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2007.10.008
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:To examine the relationships between children's moderate-to-vigorous physical activity (MVPA), sedentary behaviours, and academic performance. DESIGN:This study investigated cross-sectional relationships between children's accelerometer-measured physical activity and sedentary behaviour patterns, and academ...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2016.02.010
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:Military-, rescue- and law-enforcement personnel require a high physical capacity including muscular strength. The present study hypothesized that 9 weeks of volume matched concurrent short frequent training sessions increases strength more efficiently than less frequent longer training sessions. DESIGN:A r...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2020.03.013
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:To investigate whether genetic variants can be correlated with tendinopathy in elite male volleyball athletes. DESIGN:Case-control study. METHODS:Fifteen single nucleotide polymorphisms within BMP4, FGF3, FGF10, FGFR1 genes were investigated in 138 elite volleyball athletes, aged between 18 and 35 years, w...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2014.02.011
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate relationships between trait emotional intelligence and emotional state changes over the course of an ultra-endurance foot race covering a route of approximately 175 miles (282 km) and held in set stages over six days. DESIGN:A repeated measures field design that soug...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2011.03.001
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:Resistance training in untrained adolescents can positively effect health-related fitness as well as improve muscular power and sports performance. The impact of resistance training on adolescent athletes is less clear. The purpose of this review is to determine the effectiveness of resistance training progr...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jsams.2012.02.005
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVES:Despite the known benefits of physical activity, the majority of adults in developed countries lead sedentary lifestyles. The community setting is a promising venue for physical activity-promoting interventions. Our objectives were to investigate the effectiveness of community-based physical activity interve...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,评审
doi:10.1016/j.jsams.2013.04.009
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:Tendinopathy, the most prevalent tendon disorder which is considered as the clinical diagnosis of pain and dysfunction, is common in sports and its prevalence is ever-increasing. Despite the lack of clarity about risk factors, various preventive interventions for tendinopathy have been investigated. The main...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,评审
doi:10.1016/j.jsams.2015.03.008
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:The vast majority of rugby union ('rugby') participants are community-based players; however, the majority of injury surveillance studies reported relate to the elite, professional game. A potential reason for this dearth of studies could be the perceived difficulty of using the consensus statement for injur...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2019.08.006
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:While there is some evidence that aerobic fitness is positively associated with executive functioning in children, evidence for a relation between children's daily physical activity and their executive functioning is limited. The objective was to examine associations between objectively measured daily physic...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2014.09.006
更新日期:2015-11-01 00:00:00
abstract::To examine the strength and direction of the relationship between physical activity level, screen use and BMI in a cohort at ages 6, 8, 10 and 14 yrs as part of a prospective longitudinal cohort study. The sample comprised 1403 males and females who participated in the follow-up survey at 14 yrs of age between 2003 an...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2011.03.011
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:To compare the efficacy of two exercise programmes in reducing pain and disability for individuals with non-specific low back pain and to examine the underlying mechanical factors related to pain and disability for individuals with NSLBP. DESIGN:A single-blind, randomized controlled trial. METHODS:Eighty p...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jsams.2014.11.006
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVES:To examine the effects of shoe type and stride length reduction on lower-extremity running mechanics and cumulative loading. DESIGN:Within-subject with four conditions: (1) control shoe at preferred stride length; (2) control shoe at 90% preferred stride length; (3) minimalist shoe at preferred stride lengt...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2016.03.003
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:This study investigated indirect measures of post-exercise parasympathetic reactivation (using heart-rate-variability, HRV) and sympathetic withdrawal (using systolic-time-intervals, STI) following upper- and lower-body exercise. DESIGN:Randomized, counter-balanced, crossover. METHODS:13 males (age 26.4±4....
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jsams.2018.01.015
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:It has been hypothesised that fatigue may be a major factor in tackle-related injury risk in rugby union and hence more injuries occur in the later stages of a game. The aim of this study is to identify changes in ball carrier or tackler proficiency characteristics, using elite level match video data, as pla...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2017.06.023
更新日期:2018-02-01 00:00:00
abstract::This study was designed to compare the acute effect of vibration exercise with a concentric-only activity (arm cranking) on concentric-only muscle action using an upper body isoinertial exercise. Twelve healthy, physically active men, 30.0y+/-6.1 (mean+/-S.D.); height 1.81m+/-0.06; and weight 83.4kg+/-9.7, performed f...
journal_title:Journal of science and medicine in sport
pub_type: 杂志文章
doi:10.1016/j.jsams.2007.04.006
更新日期:2008-11-01 00:00:00