Abstract:
:Aim We aimed to study the dimensions, systolic and diastolic functions of the left ventricle; dimensions and elasticity of the aorta; and carotid intima-media thickness and flow-mediated dilatation of the brachial artery in mitral valve prolapse. METHODS:The study group consisted of 43 patients (mean age=13.3±3.9) and 42 healthy children (mean age=12.9±3.4). Left ventricular end-diastolic, end-systolic, left atrial diameters, interventricular septum, and left ventricular posterior wall thickness were measured. Ejection and shortening fractions were calculated by M-mode. Measurements were adjusted to the body surface area. Mitral annulus, and systolic and diastolic diameters of the aortic annulus and aorta at each level were obtained; z-scores, aortic strain, distensibility, stiffness index were calculated. Carotid intima-media thickness and flow-mediated dilatation were studied. Patients were classified as classical/non-classical mitral valve prolapse and younger/older patients. RESULTS:Left ventricular end-systolic, end-diastolic, and left atrial diameters (p=0.009, p=0.024, p=0.001) and aortic z-scores at annulus, sinus valsalva, and sinotubuler junction were larger (p=0.008, p=0.003, p=0.002, respectively) in the mitral valve prolapse group. Aortic strain and distensibility increased and stiffness decreased at the ascending aorta in the patient group (p=0.012, 0.020, p=0.019, respectively). Classical mitral valve prolapse had lower strain and distensibility and higher stiffness of the aorta at sinus valsalva level (p=0.010, 0.027, 0.004, respectively). Carotid intima-media thickness was thinner in the patient group, especially in the non-classical mitral valve prolapse group (p=0.037). Flow-mediated dilatation did not differ among the groups. CONCLUSION:Mitral valve prolapse is a systemic disease of the connective tissue causing enlarged cardiac chambers and increased elasticity of the aorta. Decreased carotid intima-media thickness in this group may indicate low atherosclerosis risk.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Erolu E,Akalın F,Çetiner N,Şaylan Çevik Bdoi
10.1017/S1047951117001950subject
Has Abstractpub_date
2018-02-01 00:00:00pages
292-301issue
2eissn
1047-9511issn
1467-1107pii
S1047951117001950journal_volume
28pub_type
杂志文章abstract::Introduction Carbon monoxide poisoning may cause myocardial toxicity and cardiac autonomic dysfunction, which may contribute to the development of life-threatening arrhythmias. We investigated the potential association between acute carbon monoxide exposure and cardiac autonomic function measured by heart rate variabi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117000944
更新日期:2017-11-01 00:00:00
abstract::Kawasaki disease constitutes an acute febrile vasculitis of unknown aetiology. It is considered the most common cause of acquired cardiac failure in children. Although standard treatment comprises intravenous immunoglobulin and aspirin, some children exhibit refractory disease, necessitating the use of alternative the...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001260
更新日期:2012-08-01 00:00:00
abstract::Several surgical approaches for completion of a total cavopulmonary connection have been established for patients with anomalies of systemic venous connection in association with a functionally univentricular heart. We report an alternative technique designed to address the problem of widely separated inferior systemi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116001311
更新日期:2017-03-01 00:00:00
abstract::An infant presented with features suggestive of an anomalous left coronary artery was found to have normal origins of both coronary arteries. Echocardiography during episodes of ischaemia showed marked aortic regurgitation with retrograde coronary flow. The left coronary leaflet was mildly hypoplastic. Surgical re-sus...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951115002024
更新日期:2015-12-01 00:00:00
abstract::Improvement in operative survival of patients with hypoplastic left heart syndrome has led to increasing emphasis on prevention of interstage mortality. Many centres have improved interstage results through programmes of home monitoring following discharge after the Norwood (Stage 1) operation. Experience with heighte...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951111001600
更新日期:2011-12-01 00:00:00
abstract::Gaucher disease is an autosomal-recessive lysosomal storage disease characterised by the accumulation of glucocerebroside in macrophages; it is caused by mutations in glucocerebrosidase gene-1 in many organ tissues such as the liver, spleen, and bone marrow. Its different clinical subtypes, according to the presence a...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951117000579
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Cardiopulmonary bypass is associated with systemic inflammatory response. Steroids suppress this response, although the therapeutic evidence remains controversial. We hypothesised that intravenous steroids in children undergoing open-heart surgery would decrease inflammation leading to better early post-oper...
journal_title:Cardiology in the young
pub_type: 杂志文章,随机对照试验
doi:10.1017/S1047951115000566
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:Our aim was to assess the immediate and short term results of closure of moderate and large patent arterial ducts using the self-expanding and repositionable Amplatzer device. METHOD:We attempted closure in 25 patients (10 Females and 15 males) using the Amplatzer occluder. Their median age was 48 months wi...
journal_title:Cardiology in the young
pub_type: 临床试验,杂志文章
doi:10.1017/s1047951100009124
更新日期:2000-05-01 00:00:00
abstract::We report a novel technique using an Amplatzer atrial septal occluder to close a defect located in the inferior-posterior portion of the interatrial septum that extended into the mouth of the inferior caval vein. Because of the close relation of the defect to the inferior caval vein, the right atrial disc was opened i...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951103000386
更新日期:2003-04-01 00:00:00
abstract::We report a patient with Down's syndrome referred to our Department of Echocardiography for evaluation after an episode of tachyarrhythmia. We diagnosed Ebstein's malformation. As far as we know, this association has been reported previously on only three occasions. We review these previous cases, describe our echocar...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:
更新日期:2003-08-01 00:00:00
abstract::We report a case of unroofed coronary sinus not associated with the persistent left superior vena cava. Definite diagnosis of the unroofed coronary sinus was obtained by trans-oesophageal echocardiography, which revealed the unroofed portion with left-to-right shunt. Real-time three-dimensional trans-oesophageal echoc...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113002400
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Protein-losing enteropathy is an infrequent but severe condition occurring after Fontan procedure. The multifactorial pathogenesis remains unclear and no single proposed treatment strategy has proven universally successful. Therefore, we sought to describe different treatment strategies and their effect on cl...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120000864
更新日期:2020-05-01 00:00:00
abstract::Herein, we present the first case of dilated cardiomyopathy due to premature constriction of the ductus arteriosus. A fetal echocardiography showed narrowing in the ductus arteriosus, and colour Doppler flow mapping could not identify blood flow through the ductus. Neonatal echocardiography revealed a left ventricular...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118001002
更新日期:2018-09-01 00:00:00
abstract::Purpose The aim of this study was to determine whether the exercise tolerance test can provide diagnostic and prognostic information regarding children and young adults and help predict outcome. METHODS:A total of 87 patients, aged 7-29 years (median 13, mean 13.4) were selected retrospectively. They underwent exerci...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117000233
更新日期:2017-09-01 00:00:00
abstract::An interarterial course of anomalous left main coronary artery originating from the right aortic coronary sinus of valsalva is a rare condition among anomalous aortic origin of the coronary artery. Various surgical options are available. We performed an alternative procedure, that is, mobilisation of the pulmonic root...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111002113
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To evaluate heart rate variability by Holter monitoring in type 1 diabetic children compared with a healthy control group and determine the factors modifying heart rate variability. METHODS:This was designed as a prospective study comparing 28 patients, diagnosed with type 1 diabetes and under follow-up, wit...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001224
更新日期:2014-10-01 00:00:00
abstract::Endothelial dysfunction has been reported in hypoxaemic patients with the Eisenmenger syndrome, but a direct correlation between levels of endothelial markers and the severity of hypoxaemia has not been explored. With this in mind, we compared the levels in the plasma of tissue-type plasminogen activator, thrombomodul...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105001381
更新日期:2005-10-01 00:00:00
abstract::A complication is an event or occurrence that is associated with a disease or a healthcare intervention, is a departure from the desired course of events, and may cause, or be associated with, suboptimal outcome. A complication does not necessarily represent a breech in the standard of care that constitutes medical ne...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951108002990
更新日期:2008-12-01 00:00:00
abstract::Tetralogy of Fallot, when associated with atrioventricular septal defect permitting shunting at ventricular level, represents a complex cyanotic congenital malformation. Experience with surgical repair is limited, and results vary considerably. Between 1984 and 1996, we repaired 14 consecutive patients with this combi...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100004728
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Flow profiles are important determinants of fluid-vessel wall interactions. The aim of this study was to assess blood flow profiles in the aorta and pulmonary trunk in patients with transposition and different ventriculoarterial connection, and hence different mechanics of the coherent pump. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112002193
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of a continuous infusion of basic fibroblast growth factor on the adaptive potential of the right ventricular myocardium after 30 days of mechanically induced overload in rats. Materials and methods We banded the pulmonary trunk, so as...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111002034
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Syncope is common in children and adolescents and most commonly represents neurocardiogenic syncope. No information has been reported regarding the effect of syncope on health-related quality of life in children. METHODS:This was a retrospective cohort study of patients seen in the Heart Institute Syncope C...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112000133
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:Developmental care of neonates with CHD is essential for proper neurodevelopment. Measurement of developmental care specific to these neonates is needed to ensure consistent implementation within and across cardiac ICUs. The purpose of this study was to psychometrically test the Developmental Care Scale for Neo...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119000337
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Fungal endocarditis classically involves dense heterogenous vegetations. However, several patients with fungal infections were noted to have myocardial changes ranging from focal brightening to nodular thickening of chordae or papillary muscles. This study evaluates whether these findings are associated with...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120003674
更新日期:2020-11-13 00:00:00
abstract:BACKGROUND:Aberrant right subclavian artery is the most common congenital aortic arch anomaly. There are a few reports concerning the clinical manifestations and follow-up of this CHD detected by echocardiographic screening. METHODS:A total of 1737 full-term neonates, with a male-to-female ratio of 900:837, received e...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118000872
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:To evaluate long-term outcome of initial aortic valve intervention in a paediatric population with congenital aortic stenosis, and to determine risk factors associated with reintervention. PATIENTS AND METHODS:From 1985 to 2009, 77 patients with congenital aortic stenosis and a mean age of 5.8±5.6 years at ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114001085
更新日期:2015-06-01 00:00:00
abstract::We report three cases of an abnormal finding of duplicated left pulmonary artery: two of these occurring in children with Kabuki syndrome and configuring the setting of a pseudo-pulmonary sling without any clinical or cardiac cross-sectional evidence of tracheal compression. The other case instead represents duplicate...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951115000281
更新日期:2016-02-01 00:00:00
abstract::We describe a three-year-old boy who presented with recurrent expectoration of bronchial casts six months following creation of a fenestrated lateral tunnel Fontan circulation for pulmonary atresia with intact ventricular septum. Cardiac catheterization demonstrated elevated central venous pressure with two areas of s...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951101000385
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:The association between long QT interval and sudden infant death syndrome has been clearly established. Several studies have been conducted to determine the evolution of the QT interval in childhood from birth, but only in full-term newborns. However, data on the QT interval in pre-term infants are extremely...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951111001958
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:To describe the echocardiographic features, underlying causes, and outcome of fetuses with dilated cardiomyopathy. DESIGN:A retrospective observational study between 1983 and 2003 at a tertiary centre for fetal cardiology. PATIENTS:Affected fetuses were identified using a computerised database. We included...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000855
更新日期:2005-08-01 00:00:00