Tracking the impact of depression in a perspective-taking task.

Abstract:

:Research has identified impairments in Theory of Mind (ToM) abilities in depressed patients, particularly in relation to tasks involving empathetic responses and belief reasoning. We aimed to build on this research by exploring the relationship between depressed mood and cognitive ToM, specifically visual perspective-taking ability. High and low depressed participants were eye-tracked as they completed a perspective-taking task, in which they followed the instructions of a 'director' to move target objects (e.g. a "teapot with spots on") around a grid, in the presence of a temporarily-ambiguous competitor object (e.g. a "teapot with stars on"). Importantly, some of the objects in the grid were occluded from the director's (but not the participant's) view. Results revealed no group-based difference in participants' ability to use perspective cues to identify the target object. All participants were faster to select the target object when the competitor was only available to the participant, compared to when the competitor was mutually available to the participant and director. Eye-tracking measures supported this pattern, revealing that perspective directed participants' visual search immediately upon hearing the ambiguous object's name (e.g. "teapot"). We discuss how these results fit with previous studies that have shown a negative relationship between depression and ToM.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Ferguson HJ,Cane J

doi

10.1038/s41598-017-13922-y

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

14821

issue

1

issn

2045-2322

pii

10.1038/s41598-017-13922-y

journal_volume

7

pub_type

杂志文章
  • Projecting groundwater storage changes in California's Central Valley.

    abstract::Accurate and detailed knowledge of California's groundwater is of paramount importance for statewide water resources planning and management, and to sustain a multi-billion-dollar agriculture industry during prolonged droughts. In this study, we use water supply and demand information from California's Department of W...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-31210-1

    authors: Massoud EC,Purdy AJ,Miro ME,Famiglietti JS

    更新日期:2018-08-27 00:00:00

  • Environmental filtering triggers community assembly of forest understorey plants in Central European pine stands.

    abstract::Habitat filtering models predict ecologically similar plant species to jointly colonize sites due to comparable environmental characteristics leading to an aggregated pattern of species spatial occurrence. Models focused on interspecific competition expect species with similar ecological requirements to be spatially s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-00255-z

    authors: Ulrich W,Sewerniak P,Puchałka R,Piwczyński M

    更新日期:2017-03-21 00:00:00

  • Nearly perfect near-infrared luminescence efficiency of Si nanocrystals: A comprehensive quantum yield study employing the Purcell effect.

    abstract::Thin layers of silicon nanocrystals (SiNC) in oxide matrix with optimized parameters are fabricated by the plasma-enhanced chemical vapor deposition. These materials with SiNC sizes of about 4.5 nm and the SiO2 barrier thickness of 3 nm reveal external quantum yield (QY) close to 50% which is near to the best chemical...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47825-x

    authors: Valenta J,Greben M,Dyakov SA,Gippius NA,Hiller D,Gutsch S,Zacharias M

    更新日期:2019-08-02 00:00:00

  • Alpha B-crystallin C-802G polymorphism and colorectal cancer susceptibility and clinical outcome in Chinese population.

    abstract::Colorectal cancer (CRC) is one of the most prevalent cancers worldwide and Alpha B-crystallin (CRYAB) protein has been identified as a prognostic biomarker for CRC. We evaluated CRYAB C-802G (rs14133)polymorphism in association with CRC risk and survival in Chinese population. We genotyped for CRYAB C-802G (rs14133), ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29589-y

    authors: Wu X,Zheng YZ,Han B,Wang K

    更新日期:2018-08-06 00:00:00

  • Electrically Tunable Gap Surface Plasmon-based Metasurface for Visible Light.

    abstract::In this paper, an electrically tunable metasuface is designed for visible regime. The device mainly consists of a V-shaped metallic metasurface, an ITO film, an electro-optic (EO) dielectric and a metal layer fabricated on a silica substrate. A continuous electrical modulation of resonant wavelength has been theoretic...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-14583-7

    authors: Guo J,Tu Y,Yang L,Zhang R,Wang L,Wang B

    更新日期:2017-10-26 00:00:00

  • Arabidopsis thaliana extracts optimized for polyphenols production as potential therapeutics for the APOE-modulated neuroinflammation characteristic of Alzheimer's disease in vitro.

    abstract::Although the cause of Alzheimer's disease (AD) is unknown, glial-induced neuroinflammation is an early symptom. Familial AD is caused by increases in amyloid-beta (Aβ) peptide, particularly soluble oligomeric (oAβ), considered a proximal neurotoxin and neuroinflammatory stimuli. APOE4, a naturally occurring genotype o...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29364

    authors: Ghura S,Tai L,Zhao M,Collins N,Che CT,Warpeha KM,LaDu MJ

    更新日期:2016-07-07 00:00:00

  • Biogeographic parallels in thermal tolerance and gene expression variation under temperature stress in a widespread bumble bee.

    abstract::Global temperature changes have emphasized the need to understand how species adapt to thermal stress across their ranges. Genetic mechanisms may contribute to variation in thermal tolerance, providing evidence for how organisms adapt to local environments. We determine physiological thermal limits and characterize ge...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73391-8

    authors: Pimsler ML,Oyen KJ,Herndon JD,Jackson JM,Strange JP,Dillon ME,Lozier JD

    更新日期:2020-10-13 00:00:00

  • Comparison of Individual Retinal Layer Thicknesses between Highly Myopic Eyes and Normal Control Eyes Using Retinal Layer Segmentation Analysis.

    abstract::The incidence of myopia is increasing worldwide, and the investigation on pathophysiology of myopia is becoming more important. This retrospective study aimed to compare the thicknesses of individual retinal layers between high-myopic and control eyes, and to evaluate the effects of age and sex on each retinal layer t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50306-w

    authors: Kim JH,Lee SH,Han JY,Kang HG,Byeon SH,Kim SS,Koh HJ,Lee SC,Kim M

    更新日期:2019-09-30 00:00:00

  • Genetic variations in olfactory receptor gene OR2AG2 in a large multigenerational family with asthma.

    abstract::It is estimated from twin studies that heritable factors account for at-least half of asthma-risk, of which genetic variants identified through population studies explain only a small fraction. Multi-generation large families with high asthma prevalence can serve as a model to identify highly penetrant genetic variant...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54718-6

    authors: Chakraborty S,Dakle P,Sinha A,Vishweswaraiah S,Nagori A,Salimath S,Prakash YS,Lodha R,Kabra SK,Ghosh B,Faruq M,Mahesh PA,Agrawal A

    更新日期:2019-12-13 00:00:00

  • Room Temperature Characteristics of Polymer-Based Low Ice Adhesion Surfaces.

    abstract::Ice adhesion is mainly dictated by surface properties, and water wettability is frequently correlated with ice adhesion strength. However, these established correlations are limited to high ice adhesion and become invalid when the ice adhesion strength is low. Here we carried out an experimental study to explore the r...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep42181

    authors: He Z,Vågenes ET,Delabahan C,He J,Zhang Z

    更新日期:2017-02-07 00:00:00

  • Hypoxia-inducible factor-1 alpha maintains mouse articular cartilage through suppression of NF-κB signaling.

    abstract::HIF-1α, an essential transcription factor under hypoxic condition, is indispensable for chondrocytes during skeletal development but its expression and roles in articular chondrocytes are yet to be revealed. We examined HIF-1α protein expression and the hypoxic condition during mouse osteoarthritis (OA) development us...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62463-4

    authors: Okada K,Mori D,Makii Y,Nakamoto H,Murahashi Y,Yano F,Chang SH,Taniguchi Y,Kobayashi H,Semba H,Takeda N,Piao W,Hanaoka K,Nagano T,Tanaka S,Saito T

    更新日期:2020-03-25 00:00:00

  • Circulating plant miRNAs can regulate human gene expression in vitro.

    abstract::While Brassica oleracea vegetables have been linked to cancer prevention, the exact mechanism remains unknown. Regulation of gene expression by cross-species microRNAs has been previously reported; however, its link to cancer suppression remains unexplored. In this study we address both issues. We confirm plant microR...

    journal_title:Scientific reports

    pub_type: 杂志文章,收录出版

    doi:10.1038/srep32773

    authors: Pastrello C,Tsay M,McQuaid R,Abovsky M,Pasini E,Shirdel E,Angeli M,Tokar T,Jamnik J,Kotlyar M,Jurisicova A,Kotsopoulos J,El-Sohemy A,Jurisica I

    更新日期:2016-09-08 00:00:00

  • Molecular mechanism: the human dopamine transporter histidine 547 regulates basal and HIV-1 Tat protein-inhibited dopamine transport.

    abstract::Abnormal dopaminergic transmission has been implicated as a risk determinant of HIV-1-associated neurocognitive disorders. HIV-1 Tat protein increases synaptic dopamine (DA) levels by directly inhibiting DA transporter (DAT) activity, ultimately leading to dopaminergic neuron damage. Through integrated computational m...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep39048

    authors: Quizon PM,Sun WL,Yuan Y,Midde NM,Zhan CG,Zhu J

    更新日期:2016-12-14 00:00:00

  • Early harvesting improves seed vigour of hybrid rice seeds.

    abstract::Maturity stage in harvesting time greatly affects seed vigour. This work aimed to scientific harvesting time of hybrid rice for being high vigour with high & stable seed yield. Field experiments of different harvesting time were conducted in 2013-2014, and germination percentage (GP), vigour index (VI), seed moisture ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29021-5

    authors: Wang X,Zheng H,Tang Q

    更新日期:2018-07-23 00:00:00

  • Author Correction: Potential damaging mutation in LRP5 from genome sequencing of the first reported chimpanzee with the Chiari malformation.

    abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-018-24993-w

    authors: Solis-Moruno M,de Manuel M,Hernandez-Rodriguez J,Fontsere C,Gomara-Castaño A,Valsera-Naranjo C,Crailsheim D,Navarro A,Llorente M,Riera L,Feliu-Olleta O,Marques-Bonet T

    更新日期:2018-05-04 00:00:00

  • Hyperspectral near infrared imaging quantifies the heterogeneity of carbon materials.

    abstract::For many applications heterogeneity is a direct indicator of material quality. Reliable determination of chemical heterogeneity is however not a trivial task. Spectral imaging can be used for determining the spatial distribution of an analyte in a sample, thus transforming each pixel of an image into a sampling cell. ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-28889-7

    authors: Mäkelä M,Geladi P

    更新日期:2018-07-11 00:00:00

  • Microfluidic model systems used to emulate processes occurring during soft particle filtration.

    abstract::Cake layer formation in membrane processes is an inevitable phenomenon. For hard particles, especially cake porosity and thickness determine the membrane flux, but when the particles forming the cake are soft, the variables one has to take into account in the prediction of cake behavior increase considerably. In this ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-39820-z

    authors: Bouhid de Aguiar I,Meireles M,Bouchoux A,Schroën K

    更新日期:2019-02-28 00:00:00

  • Spin-relaxation time in materials with broken inversion symmetry and large spin-orbit coupling.

    abstract::We study the spin-relaxation time in materials where a large spin-orbit coupling (SOC) is present which breaks the spatial inversion symmetry. Such a spin-orbit coupling is realized in zincblende structures and heterostructures with a transversal electric field and the spin relaxation is usually described by the so-ca...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-09759-0

    authors: Szolnoki L,Kiss A,Dóra B,Simon F

    更新日期:2017-08-30 00:00:00

  • Gene presence-absence variation associates with quantitative Verticillium longisporum disease resistance in Brassica napus.

    abstract::Although copy number variation (CNV) and presence-absence variation (PAV) have been discovered in selected gene families in most crop species, the global prevalence of these polymorphisms in most complex genomes is still unclear and their influence on quantitatively inherited agronomic traits is still largely unknown....

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-61228-3

    authors: Gabur I,Chawla HS,Lopisso DT,von Tiedemann A,Snowdon RJ,Obermeier C

    更新日期:2020-03-05 00:00:00

  • Visuomotor deficiency in panx1a knockout zebrafish is linked to dopaminergic signaling.

    abstract::Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play roles in the nervous system. The analysis of roles in both standard and pathological conditions benefits from a model organism with rapid development and early onset of behaviors. Such a model was developed by ablating the zebrafish panx1a gene using T...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-66378-y

    authors: Safarian N,Whyte-Fagundes P,Zoidl C,Grigull J,Zoidl G

    更新日期:2020-06-12 00:00:00

  • Lead palladium titanate: A room temperature nanoscale multiferroic thin film.

    abstract::The discovery of single-phase multiferroic materials and the understanding of coupling mechanisms between their spin and polarization is important from the point of view of next generation logic and memory devices. Herein we report the fabrication, dielectric, ferroelectric, piezo-response force microscopy, and magnet...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59961-w

    authors: Mishra KK,Instan AA,Kumari S,Scott JF,Katiyar RS

    更新日期:2020-02-19 00:00:00

  • BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.

    abstract::Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure. Using a screen of small molecule epigenetic probes we identified three compounds which inhibited myogenic differentiation in C2C12 myoblasts; (+)-JQ1, PFI-1, and Bromos...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-06483-7

    authors: Roberts TC,Etxaniz U,Dall'Agnese A,Wu SY,Chiang CM,Brennan PE,Wood MJA,Puri PL

    更新日期:2017-07-21 00:00:00

  • Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis.

    abstract::Cardiac damage associated with iron overload is the most common cause of morbidity and mortality in patients with hereditary hemochromatosis, but the precise mechanisms leading to disease progression are largely unexplored. Here we investigated the effects of iron overload and age on cardiac hypertrophy using 1-, 5- a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05810-2

    authors: Sukumaran A,Chang J,Han M,Mintri S,Khaw BA,Kim J

    更新日期:2017-07-18 00:00:00

  • Comparative metagenomics reveals taxonomically idiosyncratic yet functionally congruent communities in periodontitis.

    abstract::The phylogenetic characteristics of microbial communities associated with periodontitis have been well studied, however, little is known about the functional endowments of this ecosystem. The present study examined 73 microbial assemblages from 25 individuals with generalized chronic periodontitis and 25 periodontally...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep38993

    authors: Dabdoub SM,Ganesan SM,Kumar PS

    更新日期:2016-12-19 00:00:00

  • A novel 96well-formatted micro-gap plate enabling drug response profiling on primary tumour samples.

    abstract::Drug-based treatments are the most widely used interventions for cancer management. Personalized drug response profiling remains inherently challenging with low cell count harvested from tumour sample. We present a 96well-formatted microfluidic plate with built-in micro-gap that preserves up to 99.2% of cells during m...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep09656

    authors: Ma WY,Hsiung LC,Wang CH,Chiang CL,Lin CH,Huang CS,Wo AM

    更新日期:2015-04-13 00:00:00

  • Temperature sensitivity differs between heart and red muscle mitochondria in mahi-mahi (Coryphaena hippurus).

    abstract::Maintaining energy balance over a wide range of temperatures is critical for an active pelagic fish species such as the mahi-mahi (Coryphaena hippurus), which can experience rapid changes in temperature during vertical migrations. Due to the profound effect of temperature on mitochondrial function, this study was desi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71741-0

    authors: Lau GY,Cox GK,Stieglitz JD,Benetti DD,Grosell M

    更新日期:2020-09-10 00:00:00

  • A New Fitting Method for Ambipolar Diffusion Length Extraction in Thin Film Structures Using Photoluminescence Measurement with Scanning Excitation.

    abstract::A new simple method is proposed to extract the ambipolar diffusion length for two-dimensional (2D) electronic transport in thin film structures using a scanning photoluminescence microscopy (SPLM) setup. No spatially-resolved photoluminescence detection methods are required. By measuring the excitation-position-depend...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62093-w

    authors: Chu CH,Mao MH,Lin YR,Lin HH

    更新日期:2020-03-23 00:00:00

  • Optical Biometry-Based Intraocular Lens Calculation and Refractive Outcomes after Phacovitrectomy for Rhegmatogenous Retinal Detachment and Epiretinal Membrane.

    abstract::We investigate the refractive error after phacovitrectomy for rhegmatogenous retinal detachment (RRD; 100 eyes) and epiretinal membrane (ERM; 102 eyes). Axial lengths were measured by optical biometry in most patients. The main outcome measures were the refractive and absolute prediction errors. The overall mean refra...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29553-w

    authors: Shiraki N,Wakabayashi T,Sakaguchi H,Nishida K

    更新日期:2018-07-27 00:00:00

  • Using Chironomus dilutus to identify toxicants and evaluate the ecotoxicity of sediments in the Haihe River Basin.

    abstract::To effectively manage a watershed and successfully restore a river system, it is very important to assess the toxicity of sediments and identify the substances causing the toxicity. Seventy-six sediments collected in the Haihe River Basin (HRB) in China were screened for acute toxicity using Chironomus dilutus. We fou...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-01631-5

    authors: Zhu X,Shan B,Tang W,Zhang C

    更新日期:2017-05-03 00:00:00

  • Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics.

    abstract::PDA is a major cause of US cancer-related deaths. Oncogenic Kras presents in 90% of human PDAs. Kras mutations occur early in pre-neoplastic lesions but are insufficient to cause PDA. Other contributing factors early in disease progression include chronic pancreatitis, alterations in epigenetic regulators, and tumor s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-77373-8

    authors: Layeghi-Ghalehsoukhteh S,Pal Choudhuri S,Ocal O,Zolghadri Y,Pashkov V,Niederstrasser H,Posner BA,Kantheti HS,Azevedo-Pouly AC,Huang H,Girard L,MacDonald RJ,Brekken RA,Wilkie TM

    更新日期:2020-11-26 00:00:00