A study of DNA polymorphism in the apolipoprotein B gene in a Japanese population.

abstract：:Intact platelets from atherosclerotic rabbits release more thromboxane B2 (TXB2) and 12-hydroxyeicosatetraenoic acid (HETE) than platelets from normal rabbits following incubation with [14C]arachidonic acid (AA). In contrast, no difference is found between homogenates of platelets from normal and atherosclerotic anima...

journal_title：Atherosclerosis

authors： Dembińska-Kièć A,Rücker W,Schönhöfer PS

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolemia (FH), which leads to premature cardiovascular events, still remains underrecognized and undertreated in most countries. Untreated FH individuals aged 20-39 years are at 100-fold higher risk of mortality from coronary heart disease compared to those of a general populati...

journal_title：Atherosclerosis

authors： Mickiewicz A,Chmara M,Futema M,Fijalkowski M,Chlebus K,Galaska R,Bandurski T,Pajkowski M,Zuk M,Wasag B,Limon J,Rynkiewicz A,Gruchala M

更新日期：2016-06-01 00:00:00

abstract：:We investigated the modulating effect of serum total triglycerides on the lipid composition of various lipoproteins, and on the response to gemfibrozil treatment. This placebo controlled study was conducted blind in 60 participants of the Helsinki Heart Study. An inverse relationship was observed between cholesterol c...

journal_title：Atherosclerosis

authors： Mänttäri M,Koskinen P,Manninen V,Huttunen JK,Frick MH,Nikkilä EA

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVE:This study investigated the relation between alcohol consumption and specific vascular events and mortality in a high risk population of patients with clinical manifestations of vascular disease and diabetes. METHODS:Patients with clinically manifest vascular disease or diabetes (n=5447) from the SMART study...

journal_title：Atherosclerosis

authors： Beulens JW,Algra A,Soedamah-Muthu SS,Visseren FL,Grobbee DE,van der Graaf Y,SMART Study Group.

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The association between cholesterol and stroke has been inconsistent. This study aimed to examine the association between total cholesterol (TC) and mortality from total stroke and stroke subtypes. METHODS:503,340 Korean adults aged 40-80 years without a history of heart disease or stroke participa...

journal_title：Atherosclerosis

authors： Yi SW,Shin DH,Kim H,Yi JJ,Ohrr H

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Genetic and environmental factors are important components of the development of atherosclerosis. Long non-coding RNA (lncRNAs) have emerged as regulators of multiple pathophysiological pathways in the cardiovascular system. Here, we investigated potential associations between lncRNAs and atheroscle...

journal_title：Atherosclerosis

authors： Arslan S,Berkan Ö,Lalem T,Özbilüm N,Göksel S,Korkmaz Ö,Çetin N,Devaux Y,Cardiolinc™ network.

更新日期：2017-11-01 00:00:00

abstract：:A potential role for the platelet Fc gammaRIIA immunoreceptor (FcR) in collagen-mediated platelet activation associated with diabetes has recently been described. This study was undertaken to prospectively determine which diabetes patient population (type 1, type 2, or both) was more likely to over express platelet Fc...

journal_title：Atherosclerosis

authors： Calverley DC,Baldermann LV,Heldt ML,Kinney GL,Hokanson JE

更新日期：2006-03-01 00:00:00

abstract：:ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase, significantly reduced both serum cholesterol and phospholipid levels in dogs, when used at a dosage higher than 10 mg/kg per day. Triglyceride levels were not consistently changed, but beta- and pre-beta-lipoproteins were preferentially redu...

journal_title：Atherosclerosis

authors： Tsujita Y,Kuroda M,Tanzawa K,Kitano N,Endo A

更新日期：1979-03-01 00:00:00

abstract：:Rabbits were fed a semipurified diet containing soy protein for 4 weeks and subsequently transferred to a semipurified diet containing soy protein plus cholesterol (2 g/kg), or a semipurified diet containing casein as protein source. One group of rabbits was fed the soy protein diet throughout the entire experimental ...

journal_title：Atherosclerosis

authors： Scholz KE,Beynen AC,West CE

更新日期：1982-07-01 00:00:00

abstract：:To test if the prevalence of genetic risk factors for coronary heart disease (CHD) is low in individuals who have reached an extremely old age, the allele frequencies of apolipoprotein E (apo E) and B (apo B) polymorphisms and plasma lipoprotein(a) levels were investigated in nonagenarians and in younger control group...

journal_title：Atherosclerosis

authors： Kervinen K,Savolainen MJ,Salokannel J,Hynninen A,Heikkinen J,Ehnholm C,Koistinen MJ,Kesäniemi YA

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND AIM:In the general population lipid-rich plaques are prone to rupture and healing of the plaque involves calcification. Patients undergoing hemodialysis have a severe derangement of mineral metabolism and calcification of the arterial tree may have different implications. METHODS:Between 2004 and 2005, ...

journal_title：Atherosclerosis

authors： Bellasi A,Ferramosca E,Ratti C,Block G,Raggi P

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Several risk prediction models for coronary heart disease (CHD) are available today, however, they only explain a modest proportion of the incidence. Circulating microRNAs (miRs) have recently been associated with processes in CHD development, and may therefore represent new potential risk markers. ...

journal_title：Atherosclerosis

authors： Velle-Forbord T,Eidlaug M,Debik J,Sæther JC,Follestad T,Nauman J,Gigante B,Røsjø H,Omland T,Langaas M,Bye A

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Using a nationwide epidemiological database, we aimed to clarify the association of fasting plasma glucose (FPG) with subsequent cardiovascular disease (CVD) risk among young adults. METHODS AND RESULTS:Medical records of 1,180,062 young adults (20-49 years old) without a prior history of CVD and w...

journal_title：Atherosclerosis

authors： Kaneko H,Itoh H,Kiriyama H,Kamon T,Fujiu K,Morita K,Michihata N,Jo T,Takeda N,Morita H,Yasunaga H,Komuro I

更新日期：2021-01-16 00:00:00

abstract：:The aim of this review was to bring together results obtained from studies on different aspects of HDL as related to CHD and atherosclerosis. As atherosclerosis is a multistep process, the various components of HDL can intervene at different stages, such as induction of monocyte adhesion molecules, prevention of LDL m...

journal_title：Atherosclerosis

authors： Stein O,Stein Y

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To determine the association of circulating P-selectin with prevalent and incident peripheral artery disease (PAD), the ankle brachial index (ABI), and change in the ABI. METHODS:The Multi-Ethnic Study of Atherosclerosis (MESA) is a prospective population-based cohort study including 6814 European descent, A...

journal_title：Atherosclerosis

authors： Wassel CL,Berardi C,Pankow JS,Larson NB,Decker PA,Hanson NQ,Tsai MY,Criqui MH,Allison MA,Bielinski SJ

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysregulation of long non-coding RNAs (lncRNAs) has been proven to be involved in the pathogenesis of coronary artery disease (CAD). However, it remains to be extensively explored. Thus, the present study aims to study expression patterns, biological functions, and diagnostic value of lncRNAs in CAD...

journal_title：Atherosclerosis

authors： Li L,Wang L,Li H,Han X,Chen S,Yang B,Hu Z,Zhu H,Cai C,Chen J,Li X,Huang J,Gu D

更新日期：2018-08-01 00:00:00

abstract：:Oxidation of low density lipoproteins (LDL) is considered a key event in the pathogenesis of atherosclerotic lesions. Disturbed generation of coagulatory and anticoagulatory factors by endothelial cells contributes to thrombosis and the progression of atherosclerosis in coronary arteries. In this study, the effects of...

journal_title：Atherosclerosis

authors： Gräfe M,Auch-Schwelk W,Hertel H,Terbeek D,Steinheider G,Loebe M,Fleck E

更新日期：1998-03-01 00:00:00

abstract：:Rabbits were continuously exposed to 200 ppm carbon monoxide. Using the same criteria as applied by earlier investigators for morphological myocardial damage, no histotoxic effect on myocardial morphology could be demonstrated when electron-microscopic investigations were performed blindly. Similarly, exposure to 0.5 ...

journal_title：Atherosclerosis

authors： Hugod C

更新日期：1981-10-01 00:00:00

abstract：:Lipoprotein(a) (Lp(a)) is regarded as an independent risk factor for Atherosclerotic cardiovascular disease. The objectives of this study were: to determine the effects of diet and exercise on Lp(a) and to evaluate the relation of Lp(a) with the lipid profile (total serum cholesterol (TC), triglycerides (TG), low dens...

journal_title：Atherosclerosis

authors： Randall OS,Feseha HB,Illoh K,Xu S,Ketete M,Kwagyan J,Tilghman C,Wrenn M

更新日期：2004-01-01 00:00:00

abstract：INTRODUCTION:Although the combination of statins with n-3 fatty acids seems to be beneficial under the lipid profile aspect, there is little information about the interaction of these two compounds on oxidative stress. OBJECTIVE:Evaluate the interaction between statins and n-3 fatty acids on oxidative stress in women,...

journal_title：Atherosclerosis

authors： Carrepeiro MM,Rogero MM,Bertolami MC,Botelho PB,Castro N,Castro IA

更新日期：2011-07-01 00:00:00

abstract：:The new millennium has brought intense focus of interest on the risk of cardiovascular disease in women. The polycystic ovary syndrome (PCOS) is a common endocrine disorder in women characterised by hyperandrogenism and oligomenorrhoea. Most women with PCOS also exhibit features of the metabolic syndrome, including in...

journal_title：Atherosclerosis

authors： Cussons AJ,Stuckey BG,Watts GF

更新日期：2006-04-01 00:00:00

abstract：:The effect of 50 mg/kg body weight Xantinol-nicotinate (XN) on serum lipids and on non-esterified fatty acids (NEFA) was tested in 94 out-patients with hyperlipoproteinemia Types IIa, IIb, IV and V. The lipids were measured before treatment, during a 3-week period of drug administration and 10 days after rejection. In...

journal_title：Atherosclerosis

authors： Haacke H,Parwaresch MR,Mäder C

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:The influence of the quality of dietary fat on some aspects of lipid metabolism-i.e. lipoprotein concentrations, post-prandial lipids and LDL size-is not completely understood, especially in healthy individuals. OBJECTIVES:Aim of this study was to evaluate the effects of different types of dietary fat (mono...

journal_title：Atherosclerosis

authors： Rivellese AA,Maffettone A,Vessby B,Uusitupa M,Hermansen K,Berglund L,Louheranta A,Meyer BJ,Riccardi G

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:We conducted a meta-analysis of relevant randomized trials to assess whether folic acid supplementation reduces the progression of atherosclerosis as measured by carotid intima-media thickness (CIMT). METHODS:This analysis included 2052 subjects from ten folic acid randomized trials with the change in CIMT ...

journal_title：Atherosclerosis

authors： Qin X,Xu M,Zhang Y,Li J,Xu X,Wang X,Xu X,Huo Y

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Vasa vasorum (VV) and lymphatic vasa vasorum (LVV) form their own networks in the adventitia. VV supply the aorta with nutrition and oxygen; however, the distribution and role of LVV remains to be determined. The purpose of this study was to investigate differences in the distribution of VV and LVV ...

journal_title：Atherosclerosis

authors： Sano M,Unno N,Sasaki T,Baba S,Sugisawa R,Tanaka H,Inuzuka K,Yamamoto N,Sato K,Konno H

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:Lipoprotein(a) [Lp(a)] consists of apolipoprotein B-100 (apoB-100) as part of an LDL-like particle and the covalently linked glycoprotein apolipoprotein(a) [apo(a)]. Detailed mechanisms of its biosynthesis, assembly, secretion and catabolism are still poorly understood. To address the Lp(a) assembly mechanism...

journal_title：Atherosclerosis

authors： Frischmann ME,Ikewaki K,Trenkwalder E,Lamina C,Dieplinger B,Soufi M,Schweer H,Schaefer JR,König P,Kronenberg F,Dieplinger H

更新日期：2012-12-01 00:00:00

abstract：:Inducible nitric oxide synthase (iNOS) has recently been shown to be present in human atherosclerotic lesions and to promote the formation of deleterious peroxynitrite. Allicin and ajoene are discussed as active compounds with regard to the beneficial effects of garlic in atherosclerosis. The aim of this study was to ...

journal_title：Atherosclerosis

authors： Dirsch VM,Kiemer AK,Wagner H,Vollmar AM

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To compare lipid-lowering efficacy of adding alirocumab to rosuvastatin versus other treatment strategies (NCT01730053). METHODS:Patients receiving baseline rosuvastatin regimens (10 or 20 mg) were randomized to: add-on alirocumab 75 mg every-2-weeks (Q2W) (1-mL subcutaneous injection via pre-filled pen); ad...

journal_title：Atherosclerosis

authors： Farnier M,Jones P,Severance R,Averna M,Steinhagen-Thiessen E,Colhoun HM,Du Y,Hanotin C,Donahue S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND & AIMS:Dysbiosis of the gut microbiota is associated with increased levels of circulating lipopolysaccharide (LPS) and subsequent activation of systemic inflammation. Diet is an important modulator of the gut microbiome. We aimed to investigate whether circulating markers of gut-related inflammation, LPS bin...

journal_title：Atherosclerosis

authors： Awoyemi A,Trøseid M,Arnesen H,Solheim S,Seljeflot I

更新日期：2019-07-01 00:00:00

abstract：:Exercise affects lipoprotein metabolism and apolipoprotein E (Apo E) genotype may alter changes in lipoprotein subclasses that occur with exercise. The present study examined the effects of Apo E genotype (APOE) on the response of lipoprotein subclass concentrations to long-term exercise. A prospective longitudinal st...

journal_title：Atherosclerosis

authors： Seip RL,Otvos J,Bilbie C,Tsongalis GJ,Miles M,Zoeller R,Visich P,Gordon P,Angelopoulos TJ,Pescatello L,Moyna N,Thompson PD

更新日期：2006-09-01 00:00:00