Novel cycloneolignans from Vernicia fordii with inhibitory effects on over-activation of BV2 cells in vitro.

abstract：:Mammalian parental genomes contribute differently to early embryonic development. Before activation of the zygotic genome, the maternal genome provides all transcripts and proteins required for the transition from a highly specialized oocyte to a pluripotent embryo. Depletion of these maternally-encoded transcripts fr...

journal_title：Scientific reports

authors： Mahadevan S,Sathappan V,Utama B,Lorenzo I,Kaskar K,Van den Veyver IB

更新日期：2017-03-20 00:00:00

abstract：:Energetic ions have been widely used to evaluate the irradiation tolerance of structural materials for nuclear power applications and to modify material properties. It is important to understand the defect production, annihilation and migration mechanisms during and after collision cascades. In this study, single crys...

journal_title：Scientific reports

authors： Lu C,Jin K,Béland LK,Zhang F,Yang T,Qiao L,Zhang Y,Bei H,Christen HM,Stoller RE,Wang L

更新日期：2016-02-01 00:00:00

abstract：:Geophysical data from the South Kara Sea reveal U-shaped erosional structures buried beneath the 50-250 m deep seafloor of the continental shelf across an area of ~32 000 km2. These structures are interpreted as thermokarst, formed in ancient yedoma terrains during Quaternary interglacial periods. Based on comparison ...

journal_title：Scientific reports

authors： Portnov A,Mienert J,Winsborrow M,Andreassen K,Vadakkepuliyambatta S,Semenov P,Gataullin V

更新日期：2018-09-25 00:00:00

abstract：:Inhibition of programmed death 1 (PD-1), expressed on activated T cells, can break through immune resistance and elicit durable responses in human melanoma as well as other types of cancers. Canine oral malignant melanoma is one of the most aggressive tumors bearing poor prognosis due to its high metastatic potency. H...

journal_title：Scientific reports

authors： Igase M,Nemoto Y,Itamoto K,Tani K,Nakaichi M,Sakurai M,Sakai Y,Noguchi S,Kato M,Tsukui T,Mizuno T

更新日期：2020-10-27 00:00:00

abstract：:A series of β-NaLuF4 crystals were synthesized via a hydrothermal method. Hexagonal phase microdisks, microprisms, and microtubes were achieved by simply changing the amount of citric acid in the initial reaction solution. Pure red upconversion (UC) luminescence can be observed in β-NaLuF4:Yb(3+), Tm(3+), Er(3+) and L...

journal_title：Scientific reports

authors： Lin H,Xu D,Li A,Teng D,Yang S,Zhang Y

更新日期：2016-06-16 00:00:00

abstract：:In this work, lamellar MnFe2O4 was successfully planted on a wood surface through the association of hydrogen bonds via the one-pot hydrothermal method. Simultaneously, the fluoroalkylsilane (FAS-17) on the surface of the MnFe2O4 layer formed long-chain or network macromolecules through a poly-condensation process and...

journal_title：Scientific reports

authors： Wang H,Yao Q,Wang C,Fan B,Sun Q,Jin C,Xiong Y,Chen Y

更新日期：2016-10-17 00:00:00

abstract：:Global Positioning System (GPS) navigation devices and applications have become ubiquitous over the last decade. However, it is unclear whether using GPS affects our own internal navigation system, or spatial memory, which critically relies on the hippocampus. We assessed the lifetime GPS experience of 50 regular driv...

journal_title：Scientific reports

authors： Dahmani L,Bohbot VD

更新日期：2020-04-14 00:00:00

abstract：:Our study focused on radiocaesium (137Cs) partitioning in forests, three vegetation periods after the Fukushima Daiichi nuclear power plant accident. 137Cs distribution in forest components (organic and mineral soil layers as well as tree compartments: stem, bark, needles, branches and roots) was measured for two Japa...

journal_title：Scientific reports

authors： Coppin F,Hurtevent P,Loffredo N,Simonucci C,Julien A,Gonze MA,Nanba K,Onda Y,Thiry Y

更新日期：2016-11-23 00:00:00

abstract：:Methicillin resistant Staphylococcus aureus (MRSA) is a major human pathogen, which causes superficial to lethal clinical infections. Neutrophils are the most abundant leukocytes in the blood and are the first defense mechanism against S. aureus infections. Here we show Staphylococcal Superantigen-Like protein 11 (SSL...

journal_title：Scientific reports

authors： Chen C,Yang C,Barbieri JT

更新日期：2019-03-12 00:00:00

abstract：:Mesenchymal stem cells (MSCs) aid the regeneration of tissues damaged by treatment with cisplatin. However, the effects of this cytotoxic drug on the stem cells have been largely unknown. Here we demonstrate that human bone marrow-derived MSCs are relatively resistant to cisplatin treatment and show resistance levels ...

journal_title：Scientific reports

authors： Nicolay NH,Lopez Perez R,Rühle A,Trinh T,Sisombath S,Weber KJ,Ho AD,Debus J,Saffrich R,Huber PE

更新日期：2016-01-25 00:00:00

abstract：:Solving river engineering problems typically requires river flow characterization, including the prediction of flow depth, flow velocity, and flood extent. Hydraulic models use governing equations of the flow in motion (conservation of mass and momentum principles) to predict the flow characteristics. However, solving...

journal_title：Scientific reports

authors： Hosseiny H,Nazari F,Smith V,Nataraj C

更新日期：2020-05-19 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Frost HK,Andersson T,Johansson S,Englund-Johansson U,Ekström P,Dahlin LB,Johansson F

更新日期：2019-07-05 00:00:00

abstract：:Calcitriol, a metabolite of vitamin D, is often used in osteoporosis clinics. However, the material has other bioactivities; for example, it accelerates angiogenesis, has anti-inflammatory properties, and inhibits oxidative stress. We investigated the effects of calcitriol in a random skin flap rat model. "McFarlane f...

journal_title：Scientific reports

authors： Zhou KL,Zhang YH,Lin DS,Tao XY,Xu HZ

更新日期：2016-01-06 00:00:00

abstract：:Focusing on the chemical basis of dietary selection while investigating the nutritional ecology of animals helps understand their feeding biology. It is also important to consider food abundance/biomass while studying the mechanism of animal food selection. We studied leaf selection in two Bornean folivorous primates ...

journal_title：Scientific reports

authors： Matsuda I,Tuuga A,Bernard H,Sugau J,Hanya G

更新日期：2013-01-01 00:00:00

abstract：:Ambient seismic noise is characterized by randomness incurred by the random position and strength of the noise sources as well as the heterogeneous properties of the medium through which it propagates. Here we use ambient noise data recorded prior to the 1996 Gjálp eruption in Iceland in order to show that a reduction...

journal_title：Scientific reports

authors： Glynn CC,Konstantinou KI

更新日期：2016-11-24 00:00:00

abstract：:The ATP-binding cassette transporter TAPL translocates polypeptides from the cytosol into the lysosomal lumen. TAPL can be divided into two functional units: coreTAPL, active in ATP-dependent peptide translocation, and the N-terminal membrane spanning domain, TMD0, responsible for cellular localization and interaction...

journal_title：Scientific reports

authors： Bock C,Löhr F,Tumulka F,Reichel K,Würz J,Hummer G,Schäfer L,Tampé R,Joseph B,Bernhard F,Dötsch V,Abele R

更新日期：2018-10-23 00:00:00

abstract：:We found the first evidence, in the last 30 years, of a renewed magmatic activity at Campi Flegrei caldera from January 2012 to June 2013. The ground deformation, observed through satellite interferometry and GPS measurements, have been interpreted as the effect of the intrusion at shallow depth (3090 ± 138 m) of 0.00...

journal_title：Scientific reports

authors： D'Auria L,Pepe S,Castaldo R,Giudicepietro F,Macedonio G,Ricciolino P,Tizzani P,Casu F,Lanari R,Manzo M,Martini M,Sansosti E,Zinno I

更新日期：2015-08-17 00:00:00

abstract：:The intrauterine environment is particularly vulnerable to environmental exposures. We previously established a mouse model that provided evidence for pregnancy complications and placental anti-angiogenesis in response to Aroclor 1254 (A-1254), a mixture of polychlorinated biphenyls (PCBs). Importantly, these effects ...

journal_title：Scientific reports

authors： Kalkunte S,Huang Z,Lippe E,Kumar S,Robertson LW,Sharma S

更新日期：2017-01-10 00:00:00

abstract：:Systemic lupus erythematosus (SLE) features a decreased pool of CD4+CD25+Foxp3+ T regulatory (Treg) cells. We had previously observed NKG2D+CD4+ T cell expansion in contrast to a decreased pool of Treg cells in SLE patients, but whether NKG2D+CD4+ T cells contribute to the decreased Treg cells remains unclear. In the ...

journal_title：Scientific reports

authors： Yang D,Tian Z,Zhang M,Yang W,Tang J,Wu Y,Ni B

更新日期：2017-04-28 00:00:00

abstract：:Identifying the unintended effects of drugs (side effects) is a very important issue in pharmacological studies. The laboratory verification of associations between drugs and side effects requires costly, time-intensive research. Thus, an approach to predicting drug side effects based on known side effects, using a co...

journal_title：Scientific reports

authors： Timilsina M,Tandan M,d'Aquin M,Yang H

更新日期：2019-07-18 00:00:00

abstract：:Microbial metabolites, produced in the intestine, have significant effects on inflammatory diseases throughout the body. Short-chain fatty acids (SCFAs) have protective effects on experimental autoimmune encephalitis (EAE) responses but the detailed roles of SCFAs and their receptors in regulating autoimmune CNS infla...

journal_title：Scientific reports

authors： Park J,Wang Q,Wu Q,Mao-Draayer Y,Kim CH

更新日期：2019-06-20 00:00:00

abstract：:Bismuth has long been a prototypical system for investigating phase transformations and melting at high pressure. Despite decades of experimental study, however, the lattice-level response of Bi to rapid (shock) compression and the relationship between structures occurring dynamically and those observed during slow (s...

journal_title：Scientific reports

authors： Gorman MG,Coleman AL,Briggs R,McWilliams RS,McGonegle D,Bolme CA,Gleason AE,Galtier E,Lee HJ,Granados E,Śliwa M,Sanloup C,Rothman S,Fratanduono DE,Smith RF,Collins GW,Eggert JH,Wark JS,McMahon MI

更新日期：2018-11-16 00:00:00

abstract：:Semisynthetic cephalosporins are widely used antibiotics currently produced by different chemical steps under harsh conditions, which results in a considerable amount of toxic waste. Biocatalytic synthesis by the cephalosporin acylase from Pseudomonas sp. strain N176 is a promising alternative. Despite intensive engin...

journal_title：Scientific reports

authors： Ferrario V,Fischer M,Zhu Y,Pleiss J

更新日期：2019-08-27 00:00:00

abstract：:Circadian clocks keep time via ~ 24 h transcriptional feedback loops. In Drosophila, CLOCK-CYCLE (CLK-CYC) activators and PERIOD-TIMELESS (PER-TIM) repressors are feedback loop components whose transcriptional status varies over a circadian cycle. Although changes in the state of activators and repressors has been cha...

journal_title：Scientific reports

authors： Mahesh G,Rivas GBS,Caster C,Ost EB,Amunugama R,Jones R,Allen DL,Hardin PE

更新日期：2020-10-21 00:00:00

abstract：:Plant extracts contain many active compounds, which are tremendously fruitful for plant defence against several insect pests. The prime objectives of the present study were to calculate the extraction yield and to evaluate the leaf extracts of Citrullus colocynthis (L.), Cannabis indica (L.) and Artemisia argyi (L.) a...

journal_title：Scientific reports

authors： Ahmed M,Peiwen Q,Gu Z,Liu Y,Sikandar A,Hussain D,Javeed A,Shafi J,Iqbal MF,An R,Guo H,Du Y,Wang W,Zhang Y,Ji M

更新日期：2020-01-16 00:00:00

abstract：:The whale shark (Rhincodon typus) is an endangered species with a declining global population. The South Ari Atoll Marine Protected Area (SAMPA), Maldives, is one of few locations globally where year-long residency of individuals occurs. This SAMPA aggregation appears to consist almost exclusively of immature males. D...

journal_title：Scientific reports

authors： Harvey-Carroll J,Stewart JD,Carroll D,Mohamed B,Shameel I,Zareer IH,Araujo G,Rees R

更新日期：2021-01-13 00:00:00

abstract：:Plutonium isotopes have primarily been injected to the stratosphere by the atmospheric nuclear weapon tests and the burn-up of the SNAP-9A satellite. Here we show by using published data that the stratospheric plutonium exponentially decreased with apparent residence time of 1.5 ± 0.5 years, and that the temporal vari...

journal_title：Scientific reports

authors： Hirose K,Povinec PP

更新日期：2015-10-28 00:00:00

abstract：:Efficient mitochondrial Ca2+ uptake takes place at contact points between the ER and mitochondria, and represents a key regulator of many cell functions. In a previous study with HeLa cells, we showed that ER-to-mitochondria Ca2+ transfer increases during the early phase of ER stress induced by tunicamycin as an adapt...

journal_title：Scientific reports

authors： Bravo-Sagua R,López-Crisosto C,Parra V,Rodriguez-Peña M,Rothermel BA,Quest AF,Lavandero S

更新日期：2016-11-03 00:00:00

abstract：:This study aimed to determine the clinicopathological features of the subtypes of ampullary carcinoma (AC) to explore the indications for endoscopic papillectomy (EP) in early AC. Fifty-seven patients with AC who underwent curative resection were retrospectively reviewed. The 0/IA stages were significantly more common...

journal_title：Scientific reports

authors： Yamamoto K,Itoi T,Nagata N,Sofuni A,Tsuchiya T,Ishii K,Tanaka R,Tonozuka R,Honjo M,Mukai S,Asai Y,Matsunami Y,Yamaguchi H,Matsubayashi J,Joyama E,Nagakawa Y

更新日期：2021-01-12 00:00:00

abstract：:Breast cancer (BC) has a higher incidence in young Lebanese woman as compared to the West. We assessed the microRNA (miRNA) microarray profile of tissues derived from Lebanese patients with early BC and performed mRNA-miRNA integration analysis. 173 miRNAs were significantly dysregulated in 45 BC versus 17 normal adja...

journal_title：Scientific reports

authors： Nassar FJ,Talhouk R,Zgheib NK,Tfayli A,El Sabban M,El Saghir NS,Boulos F,Jabbour MN,Chalala C,Boustany RM,Kadara H,Zhang Z,Zheng Y,Joyce B,Hou L,Bazarbachi A,Calin G,Nasr R

更新日期：2017-12-04 00:00:00