miR-29b regulates expression of collagens I and III in chondrogenically differentiating BMSC in an osteoarthritic environment.

abstract：:The purpose of this study was to evaluate changes in the prevalence and risk factors of cognitive impairment (CI) by analyzing and comparing two cross-sectional epidemiological surveys of CI and its subtypes were performed in a rural area of northern China between 2010 and 2015. Residents aged ≥60 years were drawn in ...

journal_title：Scientific reports

authors： Lu H,Wang XD,Shi Z,Yue W,Zhang Y,Liu S,Liu S,Zhao L,Xiang L,Zhang Y,Guan Y,Su W,Li Z,Wang J,Wisniewski T,Ji Y

更新日期：2019-01-29 00:00:00

abstract：:Highly Tm(3+) doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm(3+) doped barium gallo-germanate (BGG) glasses....

journal_title：Scientific reports

authors： Wen X,Tang G,Yang Q,Chen X,Qian Q,Zhang Q,Yang Z

更新日期：2016-02-01 00:00:00

abstract：:We determined the nearly complete mitochondrial genomes of the Arctic Calanus glacialis and its North Atlantic sibling Calanus finmarchicus, which are key zooplankton components in marine ecosystems. The sequenced part of C. glacialis mitogenome is 27,342 bp long and consists of two contigs, while for C. finmarchicus ...

journal_title：Scientific reports

authors： Weydmann A,Przyłucka A,Lubośny M,Walczyńska KS,Serrão EA,Pearson GA,Burzyński A

更新日期：2017-10-20 00:00:00

abstract：:E-mail has become the main carrier of spreading malicious software and been widely used for phishing, even high-level persistent threats. The e-mail accounts with high social reputation are primary targets to be attacked and utilized by attackers, suffering a lot of probing attacks for a long time. In this paper, in o...

journal_title：Scientific reports

authors： Wen Y,Chen X,Zeng X,Wang W

更新日期：2020-04-29 00:00:00

abstract：:Aluminium nitride (AlN) is a promising semiconductor material for use as a substrate in high-power, high-frequency electronic and deep-ultraviolet optoelectronic devices. We study the feasibility of a novel AlN fabrication technique by using the Al/GaN substitution reaction method. The substitution method we propose h...

journal_title：Scientific reports

authors： Noorprajuda M,Ohtsuka M,Adachi M,Fukuyama H

更新日期：2020-08-03 00:00:00

abstract：:The major components of vitelline membrane (VM) are ovomucin, VM outer (VMO) I and VMO II. At present, the distribution pattern of maternal cells on the VM has not been described in detail. In this study, the existence and distribution characteristics of maternal cells on VM were observed. There were more than 3.2 × 1...

journal_title：Scientific reports

authors： Li Q,Li W,Li X,Liu L,Zhang Y,Guo Y,Chen X,Xu G,Zheng J

更新日期：2017-07-26 00:00:00

abstract：:Potassium (K+) channels shape the response properties of neurons. Although enormous progress has been made to characterize K+ channels in the primary auditory neurons, the molecular identities of many of these channels and their contributions to hearing in vivo remain unknown. Using a combination of RNA sequencing and...

journal_title：Scientific reports

authors： Reijntjes DOJ,Lee JH,Park S,Schubert NMA,van Tuinen M,Vijayakumar S,Jones TA,Jones SM,Gratton MA,Xia XM,Yamoah EN,Pyott SJ

更新日期：2019-02-22 00:00:00

abstract：:A new electrically small antenna with size ka = 0.415 is presented, fabricated and measured in this work. This is intrinsically matched to 50 Ω, has omni-directional and linear-polarized radiation pattern in the horizontal plane with maximum directivity of 1.75 dBi and simulated radiation efficiency of 93%. The antenn...

journal_title：Scientific reports

authors： Assimonis SD,Fusco V,Georgiadis A,Samaras T

更新日期：2018-10-09 00:00:00

abstract：:Epidemiology of acute kidney injury (AKI) in developing countries is under-studied. We evaluated the risk and prognosis of AKI in patients admitted to intensive care units (ICUs) in Egypt. We recruited consecutive adults admitted to ICUs in Alexandria Teaching Hospitals over six months. We used the KDIGO criteria for ...

journal_title：Scientific reports

authors： Abd ElHafeez S,Tripepi G,Quinn R,Naga Y,Abdelmonem S,AbdelHady M,Liu P,James M,Zoccali C,Ravani P

更新日期：2017-12-07 00:00:00

abstract：:We propose a polarization beam splitter (PBS) with a footprint of only 600 × 790 nm2 operating at a wavelength of λ = 1550 nm, which is the smallest PBS ever demonstrated. This device uses CMOS-compatible materials, namely, silicon and silica. The present PBS comprises two Si waveguides with different geometrical aspe...

journal_title：Scientific reports

authors： Lai MS,Huang CC

更新日期：2017-07-03 00:00:00

abstract：:The combination of a solid-phase microextraction process with graphite furnace atomic absorption spectrometry provides a very sensitive determination method for determining chromium in waters. Freshly prepared ferrite particles are used to retain the chromium species, and then separated by a magnet without the need fo...

journal_title：Scientific reports

authors： López-García I,Marín-Hernández JJ,Hernández-Córdoba M

更新日期：2020-03-24 00:00:00

abstract：:Growing evidence suggests persistent mitochondrial permeability transition pore (mPTP) opening is a key pathophysiological event in cell death underlying a variety of diseases. While it has long been clear the mPTP is a druggable target, current agents are limited by off-target effects and low therapeutic efficacy. Th...

journal_title：Scientific reports

authors： Briston T,Lewis S,Koglin M,Mistry K,Shen Y,Hartopp N,Katsumata R,Fukumoto H,Duchen MR,Szabadkai G,Staddon JM,Roberts M,Powney B

更新日期：2016-11-25 00:00:00

abstract：:Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of...

journal_title：Scientific reports

authors： Wei T,Li M,Wu C,Yan XY,Fan Y,Di Z,Wu J

更新日期：2013-01-01 00:00:00

abstract：:Autophagy is a major regulator of pancreatic beta cell homeostasis. Altered autophagic activity has been implicated in the beta cells of patients with type 2 diabetes, and in the beta cells of obese diabetic rodents. Here, we show that autophagy was induced in beta cells by either a high-fat diet or a combined high-fa...

journal_title：Scientific reports

authors： Sheng Q,Xiao X,Prasadan K,Chen C,Ming Y,Fusco J,Gangopadhyay NN,Ricks D,Gittes GK

更新日期：2017-11-27 00:00:00

abstract：:Wooden shipwrecks are a significant part of the underwater cultural heritage. In 2007, the Nanhai No. 1 shipwreck was salvaged from the seabed and moved into the Marine Silk Road Museum, where it is still stored in a water tank. We analysed the microbial communities colonizing the hull surface of the Nanhai No. 1 ship...

journal_title：Scientific reports

authors： Liu Z,Fu T,Hu C,Shen D,Macchioni N,Sozzi L,Chen Y,Liu J,Tian X,Ge Q,Feng Z,Liu H,Zhang Z,Pan J

更新日期：2018-05-08 00:00:00

abstract：:Lower corrected calcium (cCa) levels are associated with a better prognosis among incident dialysis patients. However, cCa frequently overestimates ionized calcium (iCa) levels. The prognostic importance of the true calcium status defined by iCa remains to be revealed. We conducted a retrospective cohort study of inci...

journal_title：Scientific reports

authors： Yamaguchi S,Hamano T,Doi Y,Oka T,Kajimoto S,Kubota K,Yasuda S,Shimada K,Matsumoto A,Hashimoto N,Sakaguchi Y,Matsui I,Isaka Y

更新日期：2020-03-10 00:00:00

abstract：:The chronic unpredictable stress (CUS) paradigm is extensively used in preclinical research. However, CUS exhibits translational inconsistencies, some of them resulting from the use of adult rodents, despite the evidence that vulnerability for many psychiatric disorders accumulates during early life. Here, we assessed...

journal_title：Scientific reports

authors： Sequeira-Cordero A,Salas-Bastos A,Fornaguera J,Brenes JC

更新日期：2019-11-22 00:00:00

abstract：:GDP-mannose pyrophosphorylase (GMP) catalyzed the formation of GDP-mannose, which serves as a donor for the biosynthesis of mannose-containing polysaccharides. In this study, three GMP genes from Dendrobium officinale (i.e., DoGMPs) were cloned and analyzed. The putative 1000 bp upstream regulatory region of these DoG...

journal_title：Scientific reports

authors： He C,Yu Z,Teixeira da Silva JA,Zhang J,Liu X,Wang X,Zhang X,Zeng S,Wu K,Tan J,Ma G,Luo J,Duan J

更新日期：2017-02-08 00:00:00

abstract：:Carbon nanotubes (CNTs) are among the most versatile nanomaterials, but their exploitation is hindered by limited dispersibility, especially in aqueous solvents. Here, we show that AP-LYS, a highly cationic soluble derivative of denatured hen egg lysozyme, is a very effective tool for the unbundling and solubilisation...

journal_title：Scientific reports

authors： Siepi M,Donadio G,Dardano P,De Stefano L,Monti DM,Notomista E

更新日期：2019-11-12 00:00:00

abstract：:Acoustic structure quantification (ASQ) is a recently developed technique widely used for detecting liver fibrosis. Ultrasound Nakagami parametric imaging based on the Nakagami distribution has been widely used to model echo amplitude distribution for tissue characterization. We explored the feasibility of using ultra...

journal_title：Scientific reports

authors： Tsui PH,Ho MC,Tai DI,Lin YH,Wang CY,Ma HY

更新日期：2016-09-08 00:00:00

abstract：ABSTARCT:The relationship between chronic kidney disease (CKD), which is defined by declined estimated glomerular filtration rate (eGFR) and/or proteinuria, and asymptomatic intracranial arterial stenosis (ICAS) is largely unknown. We conducted a population-based, cross-sectional study by recruiting 5209 participants f...

journal_title：Scientific reports

authors： Li Z,Li J,Wang A,Pan H,Wu S,Zhao X

更新日期：2017-07-04 00:00:00

abstract：:Ultraviolet radiation (UVR) is a major environmental genotoxic agent. In skin, it can lead to the formation of mutagenic DNA damage. Several mechanisms are in place to prevent the conversion of these DNA damage into skin cancer-driver mutations. An important mutation prevention mechanism is the programmed cell death, ...

journal_title：Scientific reports

authors： Gary AS,Rochette PJ

更新日期：2020-11-03 00:00:00

abstract：:Human epididymis protein 4 (HE4) has been used as a biomarker of endometrial cancer (EC) in clinical practice. However, there remains a lack of systemic research on the critical values of HE4 for diagnosing different clinical stages and pathological types of EC. This study investigated the accuracy of human epididymis...

journal_title：Scientific reports

authors： Liu J,Han L,Jiao Z

更新日期：2021-01-12 00:00:00

abstract：:Humans interact with the oceans in diverse and profound ways. The scope, magnitude, footprint and ultimate cumulative impacts of human activities can threaten ocean ecosystems and have changed over time, resulting in new challenges and threats to marine ecosystems. A fundamental gap in understanding how humanity is af...

journal_title：Scientific reports

authors： Halpern BS,Frazier M,Afflerbach J,Lowndes JS,Micheli F,O'Hara C,Scarborough C,Selkoe KA

更新日期：2019-08-12 00:00:00

abstract：:Malaria in India, while decreasing, remains a serious public health problem, and the contribution of submicroscopic and asymptomatic infections to its persistence is poorly understood. We conducted community surveys and clinic studies at three sites in India differing in their eco-epidemiologies: Chennai (Tamil Nadu),...

journal_title：Scientific reports

authors： van Eijk AM,Sutton PL,Ramanathapuram L,Sullivan SA,Kanagaraj D,Priya GSL,Ravishankaran S,Asokan A,Sangeetha V,Rao PN,Wassmer SC,Tandel N,Patel A,Desai N,Choubey S,Ali SZ,Barla P,Oraon RR,Mohanty S,Mishra S,Kale S

更新日期：2019-11-19 00:00:00

abstract：:Evidence on the association between dietary fiber intake and pancreatic cancer risk has been controversial. Therefore, we carried out this meta-analysis to summarize available evidence from epidemiologic studies on this point. Relevant studies were identified by searching PubMed, Embase and Web of Science databases as...

journal_title：Scientific reports

authors： Wang CH,Qiao C,Wang RC,Zhou WP

更新日期：2015-06-02 00:00:00

abstract：:Can humans produce well-timed blink responses to a neutral stimulus voluntarily, without receiving any blink-eliciting, unconditional, stimulus? And if they can, to what degree does classical eyeblink conditioning depend on volition? Here we show that voluntary blink responses learned in two paradigms that did not inv...

journal_title：Scientific reports

authors： Rasmussen A,Jirenhed DA

更新日期：2017-06-13 00:00:00

abstract：:In this paper, we demonstrate and thoroughly analyze the activation volumetric properties of selected liquid crystals in the nematic and crystalline E phases in comparison with those reported for glass-forming liquids. In the analysis, we have employed and evaluated two entropic models (based on either total or config...

journal_title：Scientific reports

authors： Grzybowski A,Urban S,Mroz S,Paluch M

更新日期：2017-02-09 00:00:00

abstract：:Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic effects have been identified for some marketed kinase inhibitors that were not detected during clinical trials. We hypothesize that more predictive cardiac funct...

journal_title：Scientific reports

authors： Conant G,Ahadian S,Zhao Y,Radisic M

更新日期：2017-09-18 00:00:00

abstract：:Synapse and dendritic spine loss induced by amyloid-β oligomers is one of the main hallmarks of the early phases of Alzheimer's disease (AD) and is directly correlated with the cognitive decline typical of this pathology. The p75 neurotrophin receptor (p75NTR) binds amyloid-β oligomers in the nM range. While it was sh...

journal_title：Scientific reports

authors： Patnaik A,Zagrebelsky M,Korte M,Holz A

更新日期：2020-08-07 00:00:00