Abstract：
:Deer are an iconic group of large mammals that originated in the Early Miocene of Eurasia (ca. 19 Ma). While there is some consensus on key relationships among their members, on the basis of molecular- or morphology-based analyses, or combined approaches, many questions remain, and the bony labyrinth has shown considerable potential for the phylogenetics of this and other groups. Here we examine its shape in 29 species of living and fossil deer using 3D geometric morphometrics and cladistics. We clarify several issues of the origin and evolution of cervids. Our results give new age estimates at different nodes of the tree and provide for the first time a clear distinction of stem and crown Cervidae. We unambiguously attribute the fossil Euprox furcatus (13.8 Ma) to crown Cervidae, pushing back the origin of crown deer to (at least) 4 Ma. Furthermore, we show that Capreolinae are more variable in bony labyrinth shape than Cervinae and confirm for the first time the monophyly of the Old World Capreolinae (including the Chinese water deer Hydropotes) based on morphological characters only. Finally, we provide evidence to support the sister group relationship of Megaloceros giganteus with the fallow deer Dama.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Mennecart B,DeMiguel D,Bibi F,Rössner GE,Métais G,Neenan JM,Wang S,Schulz G,Müller B,Costeur Ldoi
10.1038/s41598-017-12848-9subject
Has Abstractpub_date
2017-10-13 00:00:00pages
13176issue
1issn
2045-2322pii
10.1038/s41598-017-12848-9journal_volume
7pub_type
杂志文章abstract：:Brain hypometabolism is a common epilepsy-related finding in both patients and animal models. Fluorodeoxyglucose positron emission tomography studies have shown that recurrent seizures lead to reduced glucose metabolism in certain brain regions, but no studies have definitively determined whether this induces epilepto...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05038-0
更新日期：2017-07-19 00:00:00
abstract：:This study was conducted to investigate prognosis and survival of patients undergoing distal subtotal gastrectomy with D2 and D2+ lymphadenectomy for patients with locally advanced gastric cancer. Overall survival rates of 416 patients with locally advanced gastric cancer were compared between D2 and D2+ lymphadenecto...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17273
更新日期：2015-11-25 00:00:00
abstract：:Progression of age can influence gait characteristics. Previous research has investigated lower extremity joint mechanics between young and elderly people in locomotion, however little is known about whether differences exist between young and middle age people. Ten young healthy subjects (22.8 ± 5.3 years) and ten mi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41750-9
更新日期：2019-04-03 00:00:00
abstract：:YidC, a bacterial member of the YidC/Alb3/Oxa1 insertase family, mediates membrane protein assembly and insertion. Cytoplasmic loops are known to have functional significance in membrane proteins such as YidC. Employing microsecond-level molecular dynamics (MD) simulations, we show that the crystallographically unreso...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-51052-9
更新日期：2019-10-08 00:00:00
abstract：:Birgus latro (coconut crab) is an edible crustacean that has experienced serious overharvesting throughout its whole habitat range; however, the negative effects of overharvesting on the genetic diversity within B. latro populations have not been elucidated. Here, we report sex ratio, body size, and genetic diversity ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66712-4
更新日期：2020-06-22 00:00:00
abstract：:Climate change-induced extinctions are estimated to eliminate one in six known species by the end of the century. One major factor that will contribute to these extinctions is extreme climatic events. Here, we show the ecological impacts of recent record warm air temperatures and simultaneous peak drought conditions i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60122-2
更新日期：2020-02-25 00:00:00
abstract：:To evaluate the efficacy and safety of CyberKnife Stereotactic Body Radiation Therapy (SBRT) in the treatment of adrenal gland metastases (AGM), we designed a large-scale multicenter retrospective study to report the safety and efficacy of SBRT for inoperable AGM. In this study, 75 (61 males, 14 females) patients with...
journal_title：Scientific reports
pub_type： 杂志文章,多中心研究
doi：10.1038/s41598-020-64770-2
更新日期：2020-05-12 00:00:00
abstract：:Available epidemiological reports on follicular lymphoma (FL) often highlight a significant discrepancy between its high and low incidence rates in Western and Eastern Europe, respectively. The reasons behind that difference are not fully understood, but underreporting is typically presumed as one of the main factors....
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-71579-6
更新日期：2020-09-03 00:00:00
abstract：:Scrapie is a lethal neurodegenerative disease of sheep and goats caused by the misfolding of the prion protein. Variants such as M142, D145, S146, H154, Q211, and K222 were experimentally found to increase resistance or extend scrapie incubation period in goats. We aimed to identify polymorphisms in the Afar and Arsi-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63874-z
更新日期：2020-04-24 00:00:00
abstract：:The G protein-coupled pituitary adenylate cyclase-activating polypeptide receptor (PAC1R) is a potential therapeutic target for endocrine, metabolic and stress-related disorders. However, many questions regarding the protein structure and dynamics of PAC1R remain largely unanswered. Using microsecond-long simulations,...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05815-x
更新日期：2017-07-14 00:00:00
abstract：:Graphene quantum dots (GQDs) have received much attention due to their novel phenomena of charge transport and light absorption/emission. The optical transitions are known to be available up to ~6 eV in GQDs, especially useful for ultraviolet (UV) photodetectors (PDs). Thus, the demonstration of photodetection gain wi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05603
更新日期：2014-07-07 00:00:00
abstract：:The stress reactivity hypothesis posits that the magnitude of cardiovascular reactions to acute stress tasks is related with future blood pressure status, heart hypertrophy, and atherosclerosis. We assessed the stress reactivity hypothesis and aimed to identify which physiological indices (blood pressure, heart-rate, ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06882
更新日期：2014-11-13 00:00:00
abstract：:Here we developed an orange light-absorbing chromoprotein named ShadowR as a novel acceptor for performing fluorescence lifetime imaging microscopy-based Förster resonance energy transfer (FLIM-FRET) measurement in living cells. ShadowR was generated by replacing hydrophobic amino acids located at the surface of the c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48604-4
更新日期：2019-08-19 00:00:00
abstract：:Sentinel lymph node (SLN) mapping using dye or radioisotopes has been performed in patients with uterine cancer. Superparamagnetic iron oxide (SPIO) can be handled safely and is taken up by lymph nodes (LNs); however, its efficacy in detecting SLNs in uterine cancer remains unknown. This pilot study evaluated the use ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64926-0
更新日期：2020-05-14 00:00:00
abstract：:Recent skin metagenomic studies have investigated the harbored viral diversity and its possible influence on healthy skin microbial populations, and tried to establish global patterns of skin-phage evolution. However, the detail associated with the phages that potentially play a role in skin health has not been invest...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30705-1
更新日期：2018-08-16 00:00:00
abstract：:Selection may favour individuals of the same population to differ consistently in nutritional preference, for example, because optimal diets covary with morphology or personality. We provided Southern field crickets (Gryllus bimaculatus) with two synthetic food sources (carbohydrates and proteins) and quantified repea...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29071
更新日期：2016-06-30 00:00:00
abstract：:We compared the cranial base of newborn Pax7-deficient and wildtype mice using a computational shape modeling technology called particle-based modeling (PBM). We found systematic differences in the morphology of the basiooccipital bone, including a broadening of the basioccipital bone and an antero-inferior inflection...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18199-9
更新日期：2017-12-20 00:00:00
abstract：:Laser radiation pressure is a basis of numerous applications in science and technology such as atom cooling, particle manipulation, material processing, etc. This light force for the case of scalar beams is proportional to the intensity-weighted wavevector known as optical current. The ability to design the optical cu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35341
更新日期：2016-10-13 00:00:00
abstract：:In this study, we reported a new technique based on laser speckle flowgraphy to record the ocular blood flow in rabbits under deep anesthesia, and proposed parameters to characterize retinal ischemia. We applied the proposed technique to study the correlation of blood flow between the eyes of normal non-anesthetized a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-24141-4
更新日期：2018-04-09 00:00:00
abstract：:The biodosimetric information is critical for evaluating the human health hazards caused by radon and its progeny. Here, we demonstrated that the formation of phosphorylated histone variant H2AX (γ-H2AX), p53-binding protein 1 (53BP1) and phosphorylated KRAB-associated protein 1 (pKAP-1) foci and their linear tracks i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38295
更新日期：2016-12-06 00:00:00
abstract：:Gelatin-coupled cellulose (GCC) microgel with whisker-like structure is prepared and used to incorporate into casein (CA) matrix to construct reinforced CA-based composite films by solution casting. The GCC microgel has excellent dispersibility and stability in water, which contributes to the hydrophobicity and signif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37848-1
更新日期：2019-02-04 00:00:00
abstract：:Soft tissue prostheses such as artificial ear, eye and nose are widely used in the maxillofacial rehabilitation. In this report we demonstrate how to fabricate soft prostheses mold with a low cost desktop 3D printer. The fabrication method used is referred to as Scanning Printing Polishing Casting (SPPC). Firstly the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06973
更新日期：2014-11-27 00:00:00
abstract：:The dependences of spreading and differentiation of stem cells plated on hydrogel and silicone gel substrates on the rigidity and porosity of the substrates have recently been a subject of some controversy. In experiments on human mesenchymal stem cells plated on soft, medium rigidity, and hard silicone gels we show t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33411
更新日期：2016-09-21 00:00:00
abstract：:Surface defect of nanomaterials is an important physical parameter which significantly influences their physical and chemical performances. In this work, high concentration of surface oxygen vancancies (SOVs) are successfully introduced on {001} facets exposed BiOBr nanosheets via a simple surface modification using p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24918
更新日期：2016-04-26 00:00:00
abstract：:Accurate characterization of the mechanical properties of brain tissue is essential for understanding the mechanisms of traumatic brain injuries and developing protective gears or facilities. However, how storage conditions might affect the mechanical properties of brain tissue remains unclear. The objective of this s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-19687-2
更新日期：2018-01-19 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-60642-x
更新日期：2020-02-21 00:00:00
abstract：:We consider the finite-temperature properties of the extended Bose-Hubbard model realized recently in an ETH experiment [Nature 532, 476 (2016)]. Competing short- and global-range interactions accommodate fascinating collective phenomena. We formulate a self-consistent mean-field theory to describe the behaviors of th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-66054-1
更新日期：2020-06-03 00:00:00
abstract：:To master linguistic communication, humans must acquire large vocabularies quickly and effortlessly. Efficient word learning might be facilitated by the ability to rapidly acquire novel word forms even outside the focus of attention, occurring within minutes of repetitive exposure and suggesting fast and automatic lex...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34029-y
更新日期：2018-10-25 00:00:00
abstract：:Complement Receptor Immunoglobulin (CRIg), selectively expressed by macrophages, plays an important role in innate immunity by promoting phagocytosis of bacteria. Thus modulation of CRIg on macrophages by cytokines can be an important mechanism by which cytokines regulate anti-microbial immunity. The effects of the cy...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-04325-0
更新日期：2017-06-22 00:00:00
abstract：:For the first time, soil core samples from the Jiuquan region have been analyzed for Pu isotopes for radioactive source identification and radiological assessment. The Jiuquan region is in downwind from the Lop Nor Chinese nuclear test (CNT) site. The high Pu inventories (13 to 546 Bq/m(2)) in most of the sampling loc...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep12262
更新日期：2015-07-17 00:00:00
