Microstructural network alterations of olfactory dysfunction in newly diagnosed Parkinson's disease.

abstract：:Age-related macular degeneration (AMD) is a chronic degenerative disease of the retina. Recent reports have highlighted the potential role of mucosal surface microbes in the pathogenesis of AMD. In this case-control study, the composition of the nasal and oral microbiota in newly diagnosed neovascular age-related macu...

journal_title：Scientific reports

authors： Rullo J,Far PM,Quinn M,Sharma N,Bae S,Irrcher I,Sharma S

更新日期：2020-03-02 00:00:00

abstract：:Under the usual approximation of treating a biological particle as a spheroidal droplet, we consider the analysis of its size and shape with the high frequency photoacoustics and develop a numerical method which can simulate its characteristic photoacoustic waves. This numerical method is based on the calculation of s...

journal_title：Scientific reports

authors： Li Y,Fang H,Min C,Yuan X

更新日期：2015-10-07 00:00:00

abstract：:A possible association between depression and either the severity of constipation or dysosmia in Parkinson's disease (PD) patients was investigated in this cross-sectional study. One-hundred six patients who had the history of PD for less than 5 years were recruited. Depression was measured using the Beck Depression I...

journal_title：Scientific reports

authors： Chang TY,Chen YH,Chang MH,Lin CH

更新日期：2020-09-23 00:00:00

abstract：:We report evidence of the transition from n- to p-type conduction of InN with increasing Mg dopant concentration by using photoconductivity (PC) measurement at room temperature. This transition is depicted as a conversion from negative to positive PC under above-bandgap optical excitation. The n- to p-type transition ...

journal_title：Scientific reports

authors： Guo L,Wang XQ,Zheng XT,Yang XL,Xu FJ,Tang N,Lu LW,Ge WK,Shen B,Dmowski LH,Suski T

更新日期：2014-03-13 00:00:00

abstract：:The real time detection of quantitative oxygen release from the cathode is performed by in-situ Gas Chromatography as a tool to not only determine the amount of oxygen release from a lithium-ion cell but also to address the safety concerns. This in-situ gas chromatography technique monitoring the gas evolution during ...

journal_title：Scientific reports

authors： Gim J,Song J,Kim S,Jo J,Kim S,Yoon J,Kim D,Hong SG,Park JH,Mathew V,Han J,Song SJ,Kim J

更新日期：2016-03-22 00:00:00

abstract：:It has been reported that non-selective autophagy of infected hepatocytes could facilitate the development of malaria in the liver stage, but the fate of parasites following selective autophagy of infected hepatocytes is still not very clear. Here, we confirmed that sporozoite infection can induce a selective autophag...

journal_title：Scientific reports

authors： Zhao C,Liu T,Zhou T,Fu Y,Zheng H,Ding Y,Zhang K,Xu W

更新日期：2016-11-30 00:00:00

abstract：:Priming improves an organism's performance upon a future stress. To test whether cold priming supports protection in spring and how it is affected by cold acclimation, we compared seven Arabidopsis accessions with different cold acclimation potentials in the field and in the greenhouse for growth, photosynthetic perfo...

journal_title：Scientific reports

authors： Cvetkovic J,Müller K,Baier M

更新日期：2017-03-09 00:00:00

abstract：:Active immunotherapy targeting β-amyloid (Aβ) is the most promising strategy to prevent or treat Alzheimer's disease (AD). Based on pre-clinical studies and clinical trials, a safe and effective AD vaccine requires a delicate balance between providing therapeutically adequate anti-Aβ antibodies and eliminating or supp...

journal_title：Scientific reports

authors： Liu S,Shi D,Wang HC,Yu YZ,Xu Q,Sun ZW

更新日期：2015-01-14 00:00:00

abstract：:A detailed molecular understanding of botulinum neurotoxin (BoNT)/host-cell-receptor interactions is fundamental both for developing strategies against botulism and for generating improved BoNT variants for medical applications. The X-ray crystal structure of the receptor-binding domain (HC) of BoNT/A1 in complex with...

journal_title：Scientific reports

authors： Benoit RM,Schärer MA,Wieser MM,Li X,Frey D,Kammerer RA

更新日期：2017-03-02 00:00:00

abstract：:Luminescent zeolites exchanged with two distinct and interacted emissive ions are vital but less-studied for the potential applications in white light emitting diodes, solar cells, optical codes, biomedicine and so on. Typical transition metal ion Mn2+ and lanthanide ion Yb3+ are adopted as a case study via their char...

journal_title：Scientific reports

authors： Ye S,Sun J,Yi X,Wang Y,Zhang Q

更新日期：2017-04-10 00:00:00

abstract：:In addition to its role in sister chromatid cohesion, genome stability and integrity, the cohesin complex is involved in gene transcription. Mutations in core cohesin subunits SMC1A, SMC3 and RAD21, or their regulators NIPBL and HDAC8, cause Cornelia de Lange syndrome (CdLS). Recent evidence reveals that gene expressi...

journal_title：Scientific reports

authors： Mannini L,C Lamaze F,Cucco F,Amato C,Quarantotti V,Rizzo IM,Krantz ID,Bilodeau S,Musio A

更新日期：2015-11-19 00:00:00

abstract：:The linkage between oxidative stress and idiopathic chronic fatigue (ICF) has not been explored in detail. This study thoroughly compared the serum levels of biomarkers for oxidative stress and antioxidants from 103 subjects with ICF (20 men and 83 women) to those of 82 healthy volunteers (27 men and 55 women). Oxidat...

journal_title：Scientific reports

authors： Lee JS,Kim HG,Lee DS,Son CG

更新日期：2018-08-27 00:00:00

abstract：:Rearing insects is expected to dramatically increase during the next few years, and this will be associated with generating high quantities of frass (insect excreta). It is necessary to find solutions allowing the efficient valorization of these by-products before a major upscaling of the industry takes place. Therefo...

journal_title：Scientific reports

authors： Houben D,Daoulas G,Faucon MP,Dulaurent AM

更新日期：2020-03-13 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) plays an important role on fibrogenesis in heart disease. MicroRNAs have exhibited as crucial regulators of cardiac homeostasis and remodeling in various heart diseases. MiR-19a-3p/19b-3p expresses with low levels in the plasma of heart failure patients. The purpose of our study ...

journal_title：Scientific reports

authors： Zou M,Wang F,Gao R,Wu J,Ou Y,Chen X,Wang T,Zhou X,Zhu W,Li P,Qi LW,Jiang T,Wang W,Li C,Chen J,He Q,Chen Y

更新日期：2016-04-21 00:00:00

abstract：:Lead (Pb) toxicity is a major environmental concern affirming the need of proper mitigation strategies. In the present work, potential of combined treatment of 24-Epibrassinolide (24-EBL) and Salicylic acid (SA) against Pb toxicity to Brassica juncea L. seedlings were evaluated. Seedlings pre-imbibed in EBL (0.1 mM) a...

journal_title：Scientific reports

authors： Kohli SK,Bali S,Tejpal R,Bhalla V,Verma V,Bhardwaj R,Alqarawi AA,Abd Allah EF,Ahmad P

更新日期：2019-03-05 00:00:00

abstract：:Spiny mice of the genus Acomys display several unique physiological traits, including menstruation and scar-free wound healing; characteristics that are exceedingly rare in mammals, and of considerable interest to the scientific community. These unique attributes, and the potential for spiny mice to accurately model h...

journal_title：Scientific reports

authors： Mamrot J,Legaie R,Ellery SJ,Wilson T,Seemann T,Powell DR,Gardner DK,Walker DW,Temple-Smith P,Papenfuss AT,Dickinson H

更新日期：2017-08-21 00:00:00

abstract：:Sub-gap density of states (DOS) is a key parameter to impact the electrical characteristics of semiconductor materials-based transistors in integrated circuits. Previously, spectroscopy methodologies for DOS extractions include the static methods, temperature dependent spectroscopy and photonic spectroscopy. However, ...

journal_title：Scientific reports

authors： Dai M,Khan K,Zhang S,Jiang K,Zhang X,Wang W,Liang L,Cao H,Wang P,Wang P,Miao L,Qin H,Jiang J,Xue L,Chu J

更新日期：2016-06-14 00:00:00

abstract：:Dating the start of intensive anthropogenic influence on ecosystems is important for identifying the conditions necessary for ecosystem recovery. However, few studies have focused on determining when anthropogenic influences on wetland began through sedimentary archives. To fill this critical gap in our knowledge, com...

journal_title：Scientific reports

authors： Cong J,Gao C,Zhang Y,Zhang S,He J,Wang G

更新日期：2016-02-24 00:00:00

abstract：:p53 and aldehyde dehydrogenase (ALDH) have been implicated in key tumorigenesis processes including cancer initiating cell (CIC) maintenance; however, the relationship between these two mediators remains poorly defined. In this study, ALDH isoform expression diversity was revealed in CICs with disparate p53 functional...

journal_title：Scientific reports

authors： Gui S,Xie X,O'Neill WQ,Chatfield-Reed K,Yu JG,Teknos TN,Pan Q

更新日期：2020-01-23 00:00:00

abstract：:Tsunamis can propagate thousands of kilometres across the ocean. Precise calculations of arrival times are essential for reliable early warning systems, determination of source and earth properties using the inverse problem, and time series modulation due to frequency dependency of phase speed. Far field observatories...

journal_title：Scientific reports

authors： Abdolali A,Kadri U,Kirby JT

更新日期：2019-11-14 00:00:00

abstract：:Iodinated contrast agent (ICA)-induced acute kidney injury (AKI) following acute coronary syndrome (ACS) is a frequent complication, which may lead to chronic kidney disease and increased mortality. Optical coherence tomography angiography (OCT-A) of the retina is new tool delivering a rapid and noninvasive assessment...

journal_title：Scientific reports

authors： Alan G,Guenancia C,Arnould L,Azemar A,Pitois S,Maza M,Bichat F,Zeller M,Gabrielle PH,Bron AM,Creuzot-Garcher C,Cottin Y

更新日期：2019-05-30 00:00:00

abstract：:Hemodialysis patients are a special group of patients with higher mortality rates. Hemodialysis patients with vitamin D deficiency {plasma levels of 25-hydroxyvitamin D [25(OH)D] below 20 ng/mL} are associated with even higher mortality rates. The prognostic importance of vitamin D deficiency in hemodialysis patients ...

journal_title：Scientific reports

authors： Hsu HJ,Wu IW,Hsu KH,Sun CY,Chen CY,Lee CC

更新日期：2020-05-05 00:00:00

abstract：:Obesity is a major cause of type 2 diabetes mellitus (T2DM) in mammals. We have previously established a zebrafish model of diet-induced obesity (DIO zebrafish) by overfeeding Artemia. Here we created DIO zebrafish using a different method to induce T2DM. Zebrafish were overfed a commercially available fish food using...

journal_title：Scientific reports

authors： Zang L,Shimada Y,Nishimura N

更新日期：2017-05-03 00:00:00

abstract：:In the present work, linoleic acid and oleic acid were isolated from Indonesian corn oil and palm oil and they were used to prepare monoacylglycerol derivatives as the antibacterial agent. Indonesian corn oil contains 57.74% linoleic acid, 19.88% palmitic acid, 11.84% oleic acid and 3.02% stearic acid. While Indonesia...

journal_title：Scientific reports

authors： Jumina J,Lavendi W,Singgih T,Triono S,Steven Kurniawan Y,Koketsu M

更新日期：2019-07-29 00:00:00

abstract：:Improving feed efficiency (FE) is a major goal of pig breeding, reducing production costs and providing sustainability to the pig industry. Reliable predictors for FE could assist pig producers. We carried out untargeted blood metabolite profiling in uncastrated males from Danbred Duroc (n = 59) and Danbred Landrace (...

journal_title：Scientific reports

authors： Carmelo VAO,Banerjee P,da Silva Diniz WJ,Kadarmideen HN

更新日期：2020-01-14 00:00:00

abstract：:High Resolution Melt (HRM) is a versatile and rapid post-PCR DNA analysis technique primarily used to differentiate sequence variants among only a few short amplicons. We recently developed a one-vs-one support vector machine algorithm (OVO SVM) that enables the use of HRM for identifying numerous short amplicon seque...

journal_title：Scientific reports

authors： Fraley SI,Athamanolap P,Masek BJ,Hardick J,Carroll KC,Hsieh YH,Rothman RE,Gaydos CA,Wang TH,Yang S

更新日期：2016-01-18 00:00:00

abstract：:The detection of pruritic (itchy) stimuli is mediated by a variety of receptors and channels expressed by primary sensory neurons. The G protein-coupled receptor (GPCR) MRGPRD is selectively expressed by a subset of mouse non-peptidergic nociceptors and functions as the molecular receptor for the itch-inducing chemica...

journal_title：Scientific reports

authors： Dong P,Guo C,Huang S,Ma M,Liu Q,Luo W

更新日期：2017-10-24 00:00:00

abstract：:Beta oscillations observed in motor cortical local field potentials (LFPs) recorded on separate electrodes of a multi-electrode array have been shown to exhibit non-zero phase shifts that organize into planar waves. Here, we generalize this concept to additional classes of salient patterns that fully describe the spat...

journal_title：Scientific reports

authors： Denker M,Zehl L,Kilavik BE,Diesmann M,Brochier T,Riehle A,Grün S

更新日期：2018-03-26 00:00:00

abstract：:The increasing antibiotic resistance evolved by Helicobacter pylori has alarmingly reduced the eradication rates of first-line therapies. To overcome the current circulating resistome, we selected a novel potential therapeutic target in order to identify new candidate drugs for treating H. pylori infection. We screene...

journal_title：Scientific reports

authors： González A,Salillas S,Velázquez-Campoy A,Espinosa Angarica V,Fillat MF,Sancho J,Lanas Á

更新日期：2019-08-05 00:00:00

abstract：:Iron (Fe) and manganese (Mn) are essential metals which, when scarce in the growth medium, are respectively taken up by the root high affinity transporters IRT1 and NRAMP1 in Arabidopsis thaliana. The molecular bases for low affinity transport however remained unknown. Since IRT1 and NRAMP1 have a broad range of subst...

journal_title：Scientific reports

authors： Castaings L,Caquot A,Loubet S,Curie C

更新日期：2016-11-16 00:00:00