Identification of isoliquiritigenin as an activator that stimulates the enzymatic production of glycyrrhetinic acid monoglucuronide.

abstract：:Risk of malaria in infants can be influenced by prenatal factors. In this study, the potential for placental parasitemia at delivery in predicting susceptibility of infants to Plasmodium falciparum (Pf) infections was evaluated. Seventy-two newborns of mothers who were placental malaria negative (PM-) and of mothers w...

journal_title：Scientific reports

authors： Tassi Yunga S,Fouda GG,Sama G,Ngu JB,Leke RGF,Taylor DW

更新日期：2018-01-09 00:00:00

abstract：:Solid-state femtosecond lasers have stimulated the broad adoption of multiphoton microscopy in the modern laboratory. However, these devices remain costly. Fiber lasers offer promise as a means to inexpensively produce ultrashort pulses of light suitable for nonlinear microscopy in compact, robust and portable devices...

journal_title：Scientific reports

authors： Davoudzadeh N,Ducourthial G,Spring BQ

更新日期：2019-03-12 00:00:00

abstract：:Muscle attachment sites (entheses) on dry bones are regularly used by paleontologists to infer soft tissue anatomy and to reconstruct behaviors of extinct organisms. This method is commonly applied to fossil hominin hand bones to assess their abilities to participate in Paleolithic stone tool behaviors. Little is know...

journal_title：Scientific reports

authors： Williams-Hatala EM,Hatala KG,Hiles S,Rabey KN

更新日期：2016-06-23 00:00:00

abstract：:Amplification of liver injury is mediated by macrophages but the signaling by which the macrophage inflammasome enhances liver injury is not completely understood. The CCAAT/Enhancer Binding Protein-β (C/EBPβ) is a critical signaling molecule for macrophages because expression of a dominant inhibitor of C/EBPβ DNA-bin...

journal_title：Scientific reports

authors： Buck M,Solis-Herruzo J,Chojkier M

更新日期：2016-04-12 00:00:00

abstract：:Morphometric correlation networks of cortical thickness, surface area, and gray matter volume have statistically different structural topology. However, there is no report directly describing their correlation patterns in view of interregional covariance. Here, we examined the characteristics of the correlation patter...

journal_title：Scientific reports

authors： Yang JJ,Kwon H,Lee JM

更新日期：2016-05-26 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Park JH,Choi S,Moon HC,Seo H,Kim JY,Hong SP,Lee BS,Kang E,Lee J,Ryu DH,Choi IS

更新日期：2018-12-14 00:00:00

abstract：:Although there is evidence that non-steroidal anti-inflammatory drugs (NSAIDs) might be able to prevent pancreatic cancer, the findings from epidemiological studies have been inconsistent. In this paper, we conducted a meta-analysis of observational studies to examine this possibility. We searched PubMed and Embase fo...

journal_title：Scientific reports

authors： Zhang YP,Wan YD,Sun YL,Li J,Zhu RT

更新日期：2015-10-21 00:00:00

abstract：:A top-down scalable method to produce flexible water and blood repellent tubes is introduced. The method is based on replication of overhanging nanostructures from an aluminum tube template to polydimethylsiloxane (PDMS) via atomic layer deposition (ALD) assisted sacrificial etching. The nanostructured PDMS/titania tu...

journal_title：Scientific reports

authors： Hoshian S,Kankuri E,Ras RHA,Franssila S,Jokinen V

更新日期：2017-11-22 00:00:00

abstract：:Microglial activation is associated with glaucoma. In the model of unilateral laser-induced ocular hypertension (OHT), the time point at which the inflammatory process peaks remains unknown. Different time points (1, 3, 5, 8, and 15 d) were compared to analyze signs of microglial activation both in OHT and contralater...

journal_title：Scientific reports

authors： Ramírez AI,de Hoz R,Fernández-Albarral JA,Salobrar-Garcia E,Rojas B,Valiente-Soriano FJ,Avilés-Trigueros M,Villegas-Pérez MP,Vidal-Sanz M,Triviño A,Ramírez JM,Salazar JJ

更新日期：2020-03-17 00:00:00

abstract：:There is a global concern about the effects of climate change driven shifts in species phenology on crop pests. Using geographically and temporally extensive data set of moth trap catches and temperatures across the cotton growing states of India, we predicted the phenology of cotton pink bollworm Pectinophora gossypi...

journal_title：Scientific reports

authors： Fand BB,Nagrare VS,Bal SK,Naik VCB,Naikwadi BV,Mahule DJ,Gokte-Narkhedkar N,Waghmare VN

更新日期：2021-01-11 00:00:00

abstract：:Ferritin has gained significant attention as a potential reporter gene for in vivo imaging by magnetic resonance imaging (MRI). However, due to the ferritin ferrihydrite core, the relaxivity and sensitivity for detection of native ferritin is relatively low. We report here on a novel chimeric magneto-ferritin reporter...

journal_title：Scientific reports

authors： Radoul M,Lewin L,Cohen B,Oren R,Popov S,Davidov G,Vandsburger MH,Harmelin A,Bitton R,Greneche JM,Neeman M,Zarivach R

更新日期：2016-05-23 00:00:00

abstract：:A reliable method for the diagnosis of minimal cardiac ischemia would meet a strong demand for the sensitive diagnosis of coronary artery disease in cardiac stress testing and risk stratification in patients with chest pain but unremarkable ECGs and biomarkers. We hypothesized that platelets accumulate early on in isc...

journal_title：Scientific reports

authors： Ziegler M,Alt K,Paterson BM,Kanellakis P,Bobik A,Donnelly PS,Hagemeyer CE,Peter K

更新日期：2016-12-02 00:00:00

abstract：:Thrombosis has proven to be extremely difficult to predict. Measuring the generation of thrombin is a very sensitive method to detect changes in the hemostatic system. We developed a method based on the generation of thrombin to further fingerprint hemostasis, which we have named thrombin dynamics. Via this method we ...

journal_title：Scientific reports

authors： de Laat-Kremers RMW,Yan Q,Ninivaggi M,de Maat M,de Laat B

更新日期：2020-07-27 00:00:00

abstract：:Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease. However, being noncoding elements, such functional introns are poorly predicted based on traditional approaches of sequ...

journal_title：Scientific reports

authors： Chorev M,Joseph Bekker A,Goldberger J,Carmel L

更新日期：2017-06-23 00:00:00

abstract：:The relative and combined effects of sleep apnea with diabetes mellitus (DM) on cardiovascular outcomes in patients undergoing coronary artery bypass grafting (CABG) remain unknown. In this secondary analysis of data from the SABOT study, 1007 patients were reclassified into four groups based on their sleep apnea and ...

journal_title：Scientific reports

authors： Aung AT,Koo CY,Tam WW,Chen Z,Kristanto W,Sim HW,Kojodjojo P,Kofidis T,Lee CH

更新日期：2020-12-10 00:00:00

abstract：:Auricle defects are important and common occurrences in forensic medicine. The accurate measurement and assessment of auricle defects is key to identifying and evaluating injury, and the currently available methods are known to be labor intensive and inaccurate. In this paper, we introduce an identification and docume...

journal_title：Scientific reports

authors： Zhan G,Han L,Li Z,Liu Z,Fu J,Zhong K

更新日期：2018-02-12 00:00:00

abstract：:Tract tracing with neuronal tracers not only represents a straightforward approach to identify axonal projection connection between regions of the nervous system at distance but also provides compelling evidence for axonal regeneration. An ideal neuronal tracer meets certain criteria including high labeling efficacy, ...

journal_title：Scientific reports

authors： Mi D,Yuan Y,Zhang Y,Niu J,Wang Y,Yan J,Yang Y,Hu W

更新日期：2019-07-09 00:00:00

abstract：:n-3 polyunsaturated fatty acids (PUFAs) and n-6 PUFAs are reported to have immunomodulatory effects, but few studies have examined these functions. Thus, we examined whether dietary n-3 and n-6 PUFAs are associated with the risk of gastric cancer and further investigated whether fatty acid desaturases 1 and 2 (FADS1 a...

journal_title：Scientific reports

authors： Lee S,Lee J,Choi IJ,Kim YW,Ryu KW,Kim YI,Kim J

更新日期：2018-02-28 00:00:00

abstract：:Cellular therapies for liver diseases and in vitro models for drug testing both require functional human hepatocytes (Hum-H), which have unfortunately been limited due to the paucity of donor liver tissues. Human pluripotent stem cells (hPSCs) represent a promising and potentially unlimited cell source to derive Hum-H...

journal_title：Scientific reports

authors： Song W,Lu YC,Frankel AS,An D,Schwartz RE,Ma M

更新日期：2015-11-23 00:00:00

abstract：:During pregnancy several maternal adaptations occur in order to support the growing fetus which are further exacerbated by gestational diabetes mellitus (GDM). Previously we developed a mouse model of GDM, however we did not evaluate alterations to energy and fat metabolism. We have also shown that alterations in lipi...

journal_title：Scientific reports

authors： Pennington KA,Dong Y,Ruano SH,van der Walt N,Sangi-Haghpeykar H,Yallampalli C

更新日期：2020-11-30 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Wallisch C,Heinze G,Rinner C,Mundigler G,Winkelmayer WC,Dunkler D

更新日期：2020-06-26 00:00:00

abstract：:This study was intended to determine the efficacy of nivolumab, we evaluated treatment response with respect to PD-1/PD-L1 SNPs among patients with NSCLC. A total of 50 patients with NSCLC were treated with nivolumab and were also evaluated for PD-1/PD-L1 single nucleotide polymorphisms (SNPs) from plasma DNA. We inve...

journal_title：Scientific reports

authors： Nomizo T,Ozasa H,Tsuji T,Funazo T,Yasuda Y,Yoshida H,Yagi Y,Sakamori Y,Nagai H,Hirai T,Kim YH

更新日期：2017-03-23 00:00:00

abstract：:Joubert syndrome (JS) is an inherited ciliopathy characterized by a distinctive cerebellar and brain stem malformation which is known as the "molar tooth sign" on axial brain images, hypotonia, and developmental delay. Approximately 25-30% of patients with JS have kidney disease and many of them progress to end-stage ...

journal_title：Scientific reports

authors： Takagi Y,Miura K,Yabuuchi T,Kaneko N,Ishizuka K,Takei M,Yajima C,Ikeuchi Y,Kobayashi Y,Takizawa T,Hisano M,Tsurusaki Y,Matsumoto N,Hattori M

更新日期：2021-01-11 00:00:00

abstract：:Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly defined. Here, we show that cargoes transported by the Kinesin-1 ad...

journal_title：Scientific reports

authors： Butkevich E,Härtig W,Nikolov M,Erck C,Grosche J,Urlaub H,Schmidt CF,Klopfenstein DR,Chua JJ

更新日期：2016-06-01 00:00:00

abstract：:Minimally invasive surgery (MIS) has shown satisfactory surgical results for the treatment of thoracic myelopathy (TM) caused by ossification of the ligamentum flavum (OLF). This study investigated the prognostic factors following MIS and was based on the retrospective analysis of OLF patients who underwent percutaneo...

journal_title：Scientific reports

authors： Li X,An B,Gao H,Zhou C,Zhao X,Ma H,Wang B,Yang H,Zhou H,Guo X,Zhu H,Qian J

更新日期：2020-01-28 00:00:00

abstract：:Climate change is a major concern in grape production worldwide. Nights have been warming much faster than the days, raising attention on the effect of night temperatures on grape and wine composition. In this study we evaluated the effect of night temperatures on grape coloration in the cv. Corvina (Vitis vinifera L....

journal_title：Scientific reports

authors： Gaiotti F,Pastore C,Filippetti I,Lovat L,Belfiore N,Tomasi D

更新日期：2018-06-07 00:00:00

abstract：:By moving the alkoxy group on the spacer from position 5 to position 4 to add another protocol for the algorithm for intermolecular and intramolecular hydrogen bonding interactions, highly regioselectivity of noncovalent synthesis of the hydrazide-based cyclic hexamers was achieved: one out of thirteen possible isomer...

journal_title：Scientific reports

authors： Yang Y,Huang F,Chen CF,Xia M,Cai Q,Qian FJ,Xiang J

更新日期：2013-01-01 00:00:00

abstract：:Bacteria show sophisticated control of their cellular organization, and many bacteria deploy different polar landmark proteins to organize the cell pole. Super-resolution microscopy, such as Photo-Activated Localization Microscopy (PALM), provides the nanoscale localization of molecules and is crucial for better under...

journal_title：Scientific reports

authors： Altinoglu I,Merrifield CJ,Yamaichi Y

更新日期：2019-04-30 00:00:00

abstract：:Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition CT scan. In-stent noise, sig...

journal_title：Scientific reports

authors： Yang J,Yang X,De Cecco CN,Duguay TM,Chen Z,Tesche C,Schoepf UJ,Chen Y

更新日期：2017-07-31 00:00:00

abstract：:Weight regain is one of the most common problems in the long-term after bariatric surgery. It is unknown if high-intensity exercise programs applied in late phases of post-surgical follow-up could counteract this trend. After a 3-year follow-up, 21 patients underwent sleeve gastrectomy were randomized into an exercise...

journal_title：Scientific reports

authors： Marc-Hernández A,Ruiz-Tovar J,Aracil A,Guillén S,Moya-Ramón M

更新日期：2020-02-20 00:00:00