Quality of Life and Slip Progression in Degenerative Spondylolisthesis Treated Nonoperatively.

Abstract:

STUDY DESIGN:A prospective cohort study of consecutive patients. OBJECTIVE:Determination of the quality of life (QoL) and prevalence of slip progression in patients with degenerative lumbar spondylolisthesis managed nonoperatively. SUMMARY OF BACKGROUND DATA:Lumbar spinal stenosis secondary to degenerative lumbar spondylolisthesis is a common radiographic diagnosis associated with chronic back pain and radicular symptoms. There is limited evidence as to the clinical course in terms of validated QoL measures, and the extent of slip progression in patients with this condition treated nonoperatively. METHODS:Validated disease-specific and generic QoL metrics including SF12 physical and mental scores [SF12-physical component summary (PCS) and SF12-mental component summary (MCS)], Oswestry Disability Index (ODI), and numeric scales for back and leg pain as well as radiographic assessment of slip extent were evaluated at initial consultation (baseline) and at a minimum of 5 years after the baseline assessment. Slip progression was defined by a >5% increase in slip percentage. RESULTS:Thirty-nine of 160 (24.4%) patients elected to switch to operative management, despite no slip progression on preoperative radiographs. Seventy spondylolisthetic levels in 66 participants were assessed after a minimum of 5 years of nonoperative management. Twenty-one participants (31.8%) had slip progression. SF12-PCS, ODI, and leg pain improved similarly in both groups (P < 0.05). SF12-MCS did not change significantly in either group. Back pain improved only in the nonprogressing group. CONCLUSION:The majority of cases of low-grade spondylolisthesis do not progress over 5 years with nonoperative management. Regardless of whether there was progression or not, the mean PCS, ODI, and leg pain improved from baseline, although symptoms remained and a significant number elected to switch to surgical management before 5 years. Back pain improved with nonoperative treatment only in those without progression. LEVEL OF EVIDENCE:2.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Cushnie D,Johnstone R,Urquhart JC,Gurr KR,Bailey SI,Bailey CS

doi

10.1097/BRS.0000000000002429

subject

Has Abstract

pub_date

2018-05-15 00:00:00

pages

E574-E579

issue

10

eissn

0362-2436

issn

1528-1159

pii

00007632-201805150-00006

journal_volume

43

pub_type

杂志文章

相关文献

SPINE文献大全
  • Peroperative three-dimensional correction of idiopathic scoliosis with the Cotrel-Dubousset procedure.

    abstract:STUDY DESIGN:A peroperative measurement technique based on magnetic fields was used to document the thoracic and lumbar vertebral changes induced by derotation of the concave rod during corrective surgery of idiopathic scoliotic deformities with Cotrel-Dubousset instrumentation. OBJECTIVES:Objective was to accurately ...

    journal_title:Spine

    pub_type: 临床试验,杂志文章

    doi:

    authors: Labelle H,Dansereau J,Bellefleur C,de Guise J,Rivard CH,Poitras B

    更新日期:1995-06-15 00:00:00

  • The influence of lumbar disc height and cross-sectional area on the mechanical response of the disc to physiologic loading.

    abstract:STUDY DESIGN:The influence of lumbar disc height and cross-sectional area on the mechanical response of the disc to physiologic loading was determined using a finite element model. OBJECTIVES:To identify which geometric characteristics are potentially related to motion segment mechanical response to applied load, such...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199909150-00003

    authors: Natarajan RN,Andersson GB

    更新日期:1999-09-15 00:00:00

  • Spine update: the biopsychosocial model and spine care.

    abstract:STUDY DESIGN:Spine Update on the biopsychosocial model. OBJECTIVE:To review and discuss the strengths and weaknesses of the application of the model to spine care. SUMMARY OF BACKGROUND DATA:The biopsychosocial model of illness has had (and will continue to have) a significant impact on spine care. It has changed-in ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181604572

    authors: Weiner BK

    更新日期:2008-01-15 00:00:00

  • Urinary Tract Infection Following Posterior Lumbar Fusion Procedures: An American College of Surgeons National Surgical Quality Improvement Program Study.

    abstract:STUDY DESIGN:Retrospective review of prospectively collected data. OBJECTIVE:To determine the incidence and risk factors for the development of a urinary tract infection (UTI) after a posterior lumbar fusion procedure. SUMMARY OF BACKGROUND DATA:UTI after surgery is common and has important clinical consequences for ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000001003

    authors: Bohl DD,Ahn J,Tabaraee E,Ahn J,Jain A,Grauer JN,Singh K

    更新日期:2015-11-01 00:00:00

  • The clinical use of magnetic resonance imaging in pyogenic vertebral osteomyelitis.

    abstract:STUDY DESIGN:Retrospective chart review of 103 cases. OBJECTIVES:To describe the clinical use of magnetic resonance imaging in a pyogenic vertebral osteomyelitis. SUMMARY OF BACKGROUND DATA:Long delays in diagnosing pyogenic vertebral osteomyelitis of the spine have been shown in many reports. Magnetic resonance imag...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199704010-00015

    authors: Carragee EJ

    更新日期:1997-04-01 00:00:00

  • 1987 Volvo award in clinical sciences. A new clinical model for the treatment of low-back pain.

    abstract::Because there is increasing concern about low-back disability and its current medical management, this analysis attempts to construct a new theoretic framework for treatment. Observations of natural history and epidemiology suggest that low-back pain should be a benign, self-limiting condition, that low back-disabilit...

    journal_title:Spine

    pub_type: 杂志文章,评审

    doi:10.1097/00007632-198709000-00002

    authors: Waddell G

    更新日期:1987-09-01 00:00:00

  • Different curve pattern and other radiographical characteristics in male and female patients with adolescent idiopathic scoliosis.

    abstract:STUDY DESIGN:Retrospective radiographical study. OBJECTIVE:To compare the sex differences in curve patterns and radiographical characteristics in patients who have adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA:Sex differences in AIS have been documented in the incidence of curve progression, respo...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3182511d0c

    authors: Wang W,Zhu Z,Zhu F,Sun C,Wang Z,Sun X,Qiu Y

    更新日期:2012-08-15 00:00:00

  • Revision spinal fusion in patients older than 75: is it worth the risks?

    abstract:STUDY DESIGN:Retrospective clinical study of a prospective database. OBJECTIVE:This study aims to determine whether revision spinal fusion surgery is worthwhile in patients older than 75 from a risk-benefit perspective. SUMMARY OF BACKGROUND DATA:The benefits of spinal fusion in patients older than 65 is well documen...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000000067

    authors: Chang MS,Chang YH,Revella J,Crandall DG

    更新日期:2014-01-01 00:00:00

  • Health outcome assessment before and after lumbar laminectomy for radiculopathy.

    abstract:STUDY DESIGN:Forty-one patients undergoing lumbar laminectomy for radiculopathy resulting from herniated discs assessed their health status using a generic health outcome instrument (Medical Outcomes Study Short Form 36) before surgery and at an average of 2 years after surgery. OBJECTIVES:To assess whether lumbar lam...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199604150-00010

    authors: Albert TJ,Mesa JJ,Eng K,McIntosh TC,Balderston RA

    更新日期:1996-04-15 00:00:00

  • The role of steroids and their effects on phospholipase A2. An animal model of radiculopathy.

    abstract:STUDY DESIGN:The possible role of phospholipase A2 in an animal model for lumbar radiculopathy and mechanisms of epidural steroid injections were studied. OBJECTIVES:To clarify the pathophysiologic mechanism of the recently proved animal model for lumbar radiculopathy and to characterize further the mechanisms of acti...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199806010-00001

    authors: Lee HM,Weinstein JN,Meller ST,Hayashi N,Spratt KF,Gebhart GF

    更新日期:1998-06-01 00:00:00

  • Comparison of in vivo and in vitro adjacent segment motion after lumbar fusion.

    abstract:STUDY DESIGN:For in vitro studies, there is no basis for choosing a "load control study" over a "displacement control" study. This study qualitatively compared results from in vitro and in vivo tests, allowing the authors to address the experimental assumptions that in vitro testing contributes to the understanding of ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199408000-00015

    authors: Dekutoski MB,Schendel MJ,Ogilvie JW,Olsewski JM,Wallace LJ,Lewis JL

    更新日期:1994-08-01 00:00:00

  • Anterior surgical management of single-level cervical disc disease: a cost-effectiveness analysis.

    abstract:STUDY DESIGN:Cost-effectiveness analysis with decision analysis and meta-analysis. OBJECTIVE:To determine the relative cost-effectiveness of anterior cervical discectomy with fusion (with autograft, allograft, or spacers), anterior cervical discectomy without fusion (ACD), and cervical disc replacement (CDR) for the t...

    journal_title:Spine

    pub_type: 杂志文章,meta分析

    doi:10.1097/BRS.0000000000000612

    authors: Lewis DJ,Attiah MA,Malhotra NR,Burnett MG,Stein SC

    更新日期:2014-12-01 00:00:00

  • Bernardino Ramazzini: the father of occupational medicine.

    abstract::Bernardino Ramazzini was born on October 4, 1633, in the small town of Capri located in the duchy of Modula, Italy. He is credited with establishing the field of occupational medicine during his lifetime. His major contributions came after 1682, when Duke Francesco II of Modena assigned him to establish a medical depa...

    journal_title:Spine

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/01.brs.0000142437.70429.a8

    authors: Pope MH

    更新日期:2004-10-15 00:00:00

  • Loss of Pelvic Incidence Correction After Long Fusion Using Iliac Screws for Adult Spinal Deformity: Cause and Effect on Clinical Outcome.

    abstract:STUDY DESIGN:Retrospective observational cohort study. OBJECTIVE:To determine change in pelvic incidence (PI) and loss of correction after long fusion with iliac screws, the effect of iliac screw loosening, and global alignment according to postoperative PI. SUMMARY OF BACKGROUND DATA:Posterior long fixation and fusi...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000002775

    authors: Oba H,Ebata S,Takahashi J,Ikegami S,Koyama K,Haro H,Kato H,Ohba T

    更新日期:2019-02-01 00:00:00

  • Trunk sway measures of postural stability during clinical balance tests in patients with chronic whiplash injury symptoms.

    abstract:STUDY DESIGN:Trunk sway occurring during clinical stance and gait tasks was compared between a group of subjects with a chronic whiplash injury, resulting from an automobile collision, and a normal collective. OBJECTIVES:To examine if population specific trunk sway patterns for stance and gait could be identified for ...

    journal_title:Spine

    pub_type: 临床试验,杂志文章

    doi:10.1097/01.BRS.0000083170.34304.A3

    authors: Sjöström H,Allum JH,Carpenter MG,Adkin AL,Honegger F,Ettlin T

    更新日期:2003-08-01 00:00:00

  • Long scoliosis fusion to the sacrum in adults with nonparalytic scoliosis. An improved method.

    abstract::The first 17 adults with nonparalytic scoliosis having long fusion to the sacrum treated with the Luque-Galveston technique were reviewed. There were 3 men and 14 women. Their average age at the time of surgery was 47 years and the mean follow-up period was 42 months. There were no neurologic complications and no pati...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199007000-00007

    authors: Saer EH 3rd,Winter RB,Lonstein JE

    更新日期:1990-07-01 00:00:00

  • The symptom of night pain in a back pain triage clinic.

    abstract:STUDY DESIGN:Prospective longitudinal study of patients attending a back pain triage clinic with night pain. OBJECTIVE:To assess the importance of the symptom of night pain in patients attending a back pain triage clinic. SUMMARY OF BACKGROUND DATA:The 1994 US Agency for Health Care Policy and Research guidelines sug...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.brs.0000176313.02258.5e

    authors: Harding IJ,Davies E,Buchanan E,Fairbank JT

    更新日期:2005-09-01 00:00:00

  • Correlation of vertebral strength topography with 3-dimensional computed tomographic structure.

    abstract:STUDY DESIGN:Biomechanical and radiographical study. OBJECTIVE:To test the hypothesis that stiffness and strength at discrete sites of human lumbar vertebrae depend on the 3-dimentional structure and density of the vertebral-body bone elements, and can be evaluated using models based on vertebral bone characteristics ...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e31826c670d

    authors: Noshchenko A,Plaseied A,Patel VV,Burger E,Baldini T,Yun L

    更新日期:2013-02-15 00:00:00

  • Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation.

    abstract:STUDY DESIGN:This retrospective study analyzes the timing of spinal metastases and the survivability of patients with cancer after the detection of spinal metastases. OBJECTIVE:To evaluate the timing of spinal metastases in primary lesions and the survivability of patients with metastatic spinal tumors. SUMMARY OF BA...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199609150-00017

    authors: Tatsui H,Onomura T,Morishita S,Oketa M,Inoue T

    更新日期:1996-09-15 00:00:00

  • Mechanical stability of thoracolumbar pedicle screw fixation. The effect of crosslinks.

    abstract:STUDY DESIGN:Pedicle screw fixation for unstable thoracolumbar spine injuries is relatively new. The effect of one or two crosslinks on rotational and lateral bending stiffness was studied. OBJECTIVE:To determine the rotational and bending stiffness values of thoracolumbar fractures fixed by the AO's internal fixation...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-199707150-00007

    authors: Lynn G,Mukherjee DP,Kruse RN,Sadasivan KK,Albright JA

    更新日期:1997-07-15 00:00:00

  • Intraarticular atlantooccipital fusion for the treatment of traumatic occipitocervical dislocation in a child: a new technique for selective stabilization with nine years follow-up.

    abstract:STUDY DESIGN:A case report of traumatic atlantooccipital dislocation (AOD) managed by intraarticular-posterior fusion from a posterior approach at the C0-C1 level with preservation of C1-C2 motion. OBJECTIVE:To present a new technique for atlantooccipital fusion with long-term follow-up. SUMMARY OF BACKGROUND DATA:Th...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3181c91fa1

    authors: Jeszenszky D,Fekete TF,Lattig F,Bognár L

    更新日期:2010-05-01 00:00:00

  • Human nucleus pulposis can respond to a pro-inflammatory stimulus.

    abstract:STUDY DESIGN:Disc tissue obtained from patients undergoing surgery for scoliosis, lumbar radiculopathy, and discogenic pain was cultured under basal and lipopolysaccharide-stimulated conditions and the medium analyzed for production of a range of pro-inflammatory mediators. OBJECTIVES:This study was conducted to confi...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.BRS.0000103341.45133.F3

    authors: Burke JG,G Watson RW,Conhyea D,McCormack D,Dowling FE,Walsh MG,Fitzpatrick JM

    更新日期:2003-12-15 00:00:00

  • Evidence of an inherited predisposition for cervical spondylotic myelopathy.

    abstract:STUDY DESIGN:A retrospective, population-based study cross-referencing a genealogic database of over 2 million Utah residents with 10 years of clinical diagnosis data from a large tertiary hospital. OBJECTIVE:The objective of this study is to determine the presence or absence of an inherited predisposition to the deve...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0b013e3182102ede

    authors: Patel AA,Spiker WR,Daubs M,Brodke DS,Cannon-Albright LA

    更新日期:2012-01-01 00:00:00

  • Opioid-free Analgesia for Posterior Spinal Fusion Surgery Using Erector Spinae Plane (ESP) Blocks in a Multimodal Anesthetic Regimen.

    abstract:STUDY DESIGN:A case report. OBJECTIVE:The aim of this study was to report the use of erector spinae plane (ESP) blocks as part of an opioid-free multimodal anesthetic regimen and its impact on postoperative pain and opioid requirements following spine surgery. SUMMARY OF BACKGROUND DATA:Posterior spinal fusion surger...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000002855

    authors: Chin KJ,Lewis S

    更新日期:2019-03-15 00:00:00

  • Repeat use of human recombinant bone morphogenetic protein-2 for second level lumbar arthrodesis.

    abstract:STUDY DESIGN:Prospective randomized controlled animal model. OBJECTIVE:The purpose of this study is to determine whether the readministration of human recombinant bone morphogenetic protein-2 (rhBMP-2) induces an immune response and inhibits successful fusion in repeat posterolateral spinal surgery. SUMMARY OF BACKGR...

    journal_title:Spine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/BRS.0b013e3181cdd396

    authors: Singh K,Dumonski M,Stanley T,Ponnappan R,Phillips FM

    更新日期:2011-02-01 00:00:00

  • Measurement Properties of the Functional Rating Index: A Systematic Review and Meta-analysis.

    abstract:STUDY DESIGN:A systematic review and meta-analysis. OBJECTIVE:To assess the measurement properties of the Functional Rating Index (FRI) and determine whether its measurement properties are comparable with other region-specific questionnaires. SUMMARY OF BACKGROUND DATA:In addition to low back pain (LBP) and neck pain...

    journal_title:Spine

    pub_type: 杂志文章,meta分析

    doi:10.1097/BRS.0000000000002690

    authors: Bai Z,Shu T,Lu J,Niu W

    更新日期:2018-11-15 00:00:00

  • Occult spinous process fractures associated with interspinous process spacers.

    abstract:STUDY DESIGN:Prospective observational study. OBJECTIVE:To provide a more accurate estimate of the rate of acute spinous process fractures associated with IPS surgery. SUMMARY OF BACKGROUND DATA:Biomechanical cadaveric studies have suggested adequate spinous process strength to support placement of interspinous proce...

    journal_title:Spine

    pub_type: 临床试验,杂志文章

    doi:10.1097/BRS.0b013e318204066a

    authors: Kim DH,Tantorski M,Shaw J,Martha J,Li L,Shanti N,Rencu T,Parazin S,Kwon B

    更新日期:2011-07-15 00:00:00

  • Anatomic studies of the circulation in the region of the vertebral end-plate in adult Greyhound dogs.

    abstract::In order to study the detailed arrangements of vascular terminations in the region of the vertebral end-plate in adult dogs, infusions of Japanese ink mixed with a suspension of barium sulfate were used to produce filling of the vascular terminations at the vertebral end-plates. Radiographs were made of the decalcifie...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/00007632-198410000-00009

    authors: Crock HV,Goldwasser M

    更新日期:1984-10-01 00:00:00

  • Assessment of human disc degeneration and proteoglycan content using T1rho-weighted magnetic resonance imaging.

    abstract:STUDY DESIGN:T1rho relaxation was quantified and correlated with intervertebral disc degeneration and proteoglycan content in cadaveric human lumbar spine tissue. OBJECTIVE:To show the use of T1rho-weighted magnetic resonance imaging (MRI) for the assessment of degeneration and proteoglycan content in the human interv...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/01.brs.0000217708.54880.51

    authors: Johannessen W,Auerbach JD,Wheaton AJ,Kurji A,Borthakur A,Reddy R,Elliott DM

    更新日期:2006-05-15 00:00:00

  • Clinical and Radiographical Differences Between Thoracic Idiopathic Spinal Cord Herniation and Spinal Arachnoid Cyst.

    abstract:STUDY DESIGN:A retrospective, multicenter, case-controlled study. OBJECTIVE:The aim of this study was to investigate the clinical and radiographical differences between thoracic idiopathic spinal cord herniation (ISCH) and spinal arachnoid cyst (SAC). SUMMARY OF BACKGROUND DATA:ISCH and SAC are relatively rare diseas...

    journal_title:Spine

    pub_type: 杂志文章

    doi:10.1097/BRS.0000000000002013

    authors: Nakashima H,Imagama S,Yagi H,Kato F,Kanemura T,Sato K,Kawakami N,Kamiya M,Yoshihara H,Ito K,Matsuyama Y,Nishida Y,Ishiguro N

    更新日期:2017-08-15 00:00:00