LncRNA DANCR promotes migration and invasion through suppression of lncRNA-LET in gastric cancer cells.

abstract：:Mitochondria are known to participate in the initiation of programmed cell death (PCD) in animals and in plants. The role of chloroplasts in PCD is still unknown. We describe a new system to study PCD in plants; namely, leaf epidermal peels. The peel represents a monolayer consisting of cells of two types: phototrophi...

journal_title：Bioscience reports

authors： Samuilov VD,Lagunova EM,Kiselevsky DB,Dzyubinskaya EV,Makarova YV,Gusev MV

更新日期：2003-04-01 00:00:00

abstract：:Partitioning in charge-sensitive dextran-poly(ethylene glycol) aqueous phase systems reveals that fixation with even small concentrations of glutaraldehyde (e.g., 0.1% w/v) changes the surface properties of cells. While fixation with larger concentrations of glutaraldehyde (i.e., 1.85%) increases erythrocyte partition...

journal_title：Bioscience reports

authors： Walter H,Krob EJ

更新日期：1989-12-01 00:00:00

abstract：:Fanconi Anemia (FA) is a rare genetic disorder characterized by developmental defects, bone marrow failure and high predisposition to cancer. The FA DNA repair pathway is required in humans to coordinate repair of DNA interstrand cross-links. The central event in the activation of the pathway is the monoubiquitination...

journal_title：Bioscience reports

authors： Frost MG,Mazloumi Aboukheili AM,Toth R,Walden H

更新日期：2020-06-26 00:00:00

abstract：:We aimed to determine the effect of 'Xiaozeng No. 1' (XZ-1) on cellular apoptosis changes of gastric epithelial dysplasia (GED) and to explore the underlying mechanism. Specimens taken from the pyloric area of the stomachs from rats in each group were subjected to Hematoxylin and Eosin (H&E) staining for pathological ...

journal_title：Bioscience reports

authors： Xu B,Zhang AM,Li F,Cui M,Han J,Cao Q

更新日期：2018-06-12 00:00:00

abstract：:Peptide sequencing of the complement system regulatory protein, factor H, permitted the synthesis of a mixed sequence oligonucleotide probe. Human liver cDNA libraries were screened and factor H-specific clones selected. No full-length clone was obtained, but the largest available clone, R2a, was found to encode the C...

journal_title：Bioscience reports

authors： Day AJ,Ripoche J,Lyons A,McIntosh B,Harris TJ,Sim RB

更新日期：1987-03-01 00:00:00

abstract：:Lung surfactant protein A (SP-A) is the most abundant surfactant-associated protein present in the lung. A receptor for SP-A has been shown to be present on A549 alveolar type II cells and on other cell types, including alveolar macrophage. The SP-A receptor on A549 cells has been identified as the collection receptor...

journal_title：Bioscience reports

authors： Malhotra R,Haurum J,Thiel S,Jensenius JC,Sim RB

更新日期：1993-04-01 00:00:00

abstract：:Decreasing extracellular sodium concentration was found to produce a contractile response of rabbit ileal smooth muscle. As the concentration decreases, the amplitude of contraction increases, thus producing a dose-dependent curve. Harmaline, a competitor for sodium, was found to inhibit the sodium gradient-dependent ...

journal_title：Bioscience reports

authors： Suleiman MS

更新日期：1985-08-01 00:00:00

abstract：:More than 60 million people in the world have been diagnosed with HIV infections since the virus was recognized as the causative agent of AIDS in the 1980s. Even though more than half of the infected patients have died, effective disease treatment and prevention measures have not been established. ART (antiretroviral ...

journal_title：Bioscience reports

authors： Choi J,Jeong Y,Han HS,Lee KH

更新日期：2014-08-18 00:00:00

abstract：:PDC (pyruvate dehydrogenase complex) is a multi-enzyme complex comprising an E1 (pyruvate decarboxylase), an E2 (dihydrolipomide acetyltransferase) and an E3 (dihydrolipoamide dehydrogenase). PDC catalyses the decarboxylation of pyruvate and forms acetyl-CoA and NADH. In the human malaria parasite Plasmodium falciparu...

journal_title：Bioscience reports

authors： Laine LM,Biddau M,Byron O,Müller S

更新日期：2015-01-14 00:00:00

abstract：:Antimicrobial peptides are a promising resource for developing novel antibiotic and even anticancer drugs. Here, a 28-mer polypeptide, Ranatuerin-2PLx (R2PLx), was identified from lyophilised skin secretions. The chemically synthetic replicates exhibited moderate and broadspectrum antimicrobial effect against various ...

journal_title：Bioscience reports

authors： Chen X,Zhang L,Ma C,Zhang Y,Xi X,Wang L,Zhou M,Burrows JF,Chen T

更新日期：2018-11-09 00:00:00

abstract：:Radioactivity from [14C] adenosine was linearly incorporated into tissue nucleotides in perfused rat hearts. All the TCA-extractable 14C was confined to the purine nucleoside phosphates for up to 1 h of perfusion. Radioactivity was also incorporated linearly into the TCA-insoluble fraction, which by 40 min accounted f...

journal_title：Bioscience reports

authors： Hutchinson WL,Bates DJ,Perrett D,Mowbray J

更新日期：1981-11-01 00:00:00

abstract：:One of the major obstacles to obtaining human cells of a defined and reproducible standard suitable for use as medical therapies is the necessity for FCS (fetal calf serum) media augmentation in routine cell culture applications. FCS has become the supplement of choice for cell culture research, as it contains an arra...

journal_title：Bioscience reports

authors： Bryan N,Andrews KD,Loughran MJ,Rhodes NP,Hunt JA

更新日期：2011-06-01 00:00:00

abstract：:Keratin 18 (KRT18) has been suggested to be overexpressed in most types of human tumor, but the expression pattern of KRT18 in colorectal cancer (CRC) remained unknown. In our research, KRT18 protein expression was markedly increased in CRC cancer tissues and cell lines compared with adjacent normal colorectal tissues...

journal_title：Bioscience reports

authors： Zhang J,Hu S,Li Y

更新日期：2019-08-13 00:00:00

abstract：:In the present study, we investigated the role of lncRNA SAMMSON in hepatocellular carcinoma (HCC). We found that SAMMSON was up-regulated in HCC tissues, and patients with high levels of SAMMSON in HCC tissues had significantly lower overall rate within 5 years after admission. miR-9-3p was down-regulated in HCC tiss...

journal_title：Bioscience reports

authors： Yang S,Cai H,Hu B,Tu J

更新日期：2019-07-05 00:00:00

abstract：:The inhibition of passive K+ influx into human red blood cells (RBC) by loop diuretics was found to be dependent on the external Na+ concentration. In the absence of external Na+, there was minimal inhibition but the influx remained dependent on Cl- ions. Thus, raising the external Na+ concentration increased the affi...

journal_title：Bioscience reports

authors： Chipperfield AR

更新日期：1985-04-01 00:00:00

abstract：:Imipramine and clorgyline, at concentrations of 0.002 M, inhibit the respiration of brain tissue by 82 and 71 per cent respectively, while chloropromazine and tranylcypromine, at concentrations of 0.01 M, inhibit it about 25 per cent. Deprenyl and amphetamine at a concentration of 0.002 M inhibit brain tissue respirat...

journal_title：Bioscience reports

authors： Nag M,Nandi N

更新日期：1991-02-01 00:00:00

abstract：:Esophageal cancer is seen with increasing incidence, but the underlying mechanism of esophageal cancer is still unknown. Transient receptor potential melastatin (TRPM) is non-selective cation channels. It has been verified that TRPM channels play crucial roles in development and progression of multiple tumors. Increas...

journal_title：Bioscience reports

authors： Lan X,Zhao J,Song C,Yuan Q,Liu X

更新日期：2019-10-30 00:00:00

abstract：:Hematopoietic pre-B cell leukemia transcription factor (PBX)-interacting protein (RRBP1) has been shown to participate in various aspects of malignancies. The clinical significance of RRBP1 and its involvement in the epithelial ovarian cancer have yet to be studied. The aim of the present study was to investigate the ...

journal_title：Bioscience reports

authors： Ma J,Ren S,Ding J,Liu S,Zhu J,Ma R,Meng F

更新日期：2019-07-23 00:00:00

abstract：:Pregnant rabbit mammary gland explants cultured with insulin, prolactin and cortisol synthesize and secrete transferrin radiolabelled with [3H]leucine or [3H]mannose. Addition of tunicamycin inhibits the glycosylation but not synthesis of the [3H]leucine-labelled polypeptide. Secretion of the non-glycosylated protein ...

journal_title：Bioscience reports

authors： Bradshaw JP,White DA

更新日期：1985-03-01 00:00:00

abstract：:Unstable angina pectoris (UA) is one of the most dangerous clinical symptoms of acute coronary syndrome due to the risk of myocardial ischemia, which can lead to high morbidity and mortality worldwide. Though there are many advantages in understanding the pathophysiology of UA, the identification of biomarkers for the...

journal_title：Bioscience reports

authors： Wang J,Xu W,Zhao H,Chen J,Zhu B,Li X,Deng D,Wang J,Liu J,Yu Y,Xiao H,Wang W

更新日期：2019-03-22 00:00:00

abstract：:Lung adenocarcinoma (LUAD) is the leading cause of cancer-related death worldwide, and its underlying mechanism remains unclear. Accumulating evidence has highlighted that long non-coding RNA (lncRNA) acts as competitive endogenous RNA (ceRNA) and plays an important role in the occurrence and development of LUAD. Here...

journal_title：Bioscience reports

authors： Yao Y,Zhang T,Qi L,Liu R,Liu G,Wang J,Song Q,Sun C

更新日期：2020-01-31 00:00:00

abstract：:miRNAs are non-coding RNA molecules typically 18-22 nucleotides long that can suppress the expression of their target genes. Several laboratories have attempted to identify miRNAs from the pig that are involved in Salmonella infection. These bioinformatics strategies using the newly available genomic sequence are gene...

journal_title：Bioscience reports

authors： Yao M,Gao W,Yang J,Liang X,Luo J,Huang T

更新日期：2016-08-31 00:00:00

abstract：:Tuberculosis (TB), a leading infectious disease caused by Mycobacterium tuberculosis strain, takes four human lives every minute globally. Paucity of knowledge on M. tuberculosis virulence and antibiotic resistance is the major challenge for tuberculosis control. We have identified 47 acetyltransferases in the M. tube...

journal_title：Bioscience reports

authors： Xie L,Yang W,Fan X,Xie J

更新日期：2019-12-20 00:00:00

abstract：:Goblet cells (GCs) are single-cell glands that produce and secrete mucin. Mucin forms a mucus layer, which can separate the materials in cavities from the intestinal epithelium and prevent the invasion of pathogenic microorganisms in various ways. GCs can also participate in the immune response through nonspecific end...

journal_title：Bioscience reports

authors： Zhang M,Wu C

更新日期：2020-10-30 00:00:00

abstract：:The effect that research on dopamine and other neutro trasmitters has on disciplines like neurology and psychiatry is described. ...

journal_title：Bioscience reports

authors： Carlsson A

更新日期：2001-12-01 00:00:00

abstract：:Understanding cell migration in a 3D microenvironment is essential as most cells encounter complex 3D extracellular matrix (ECM) in vivo Although interactions between cells and ECM have been studied previously on 2D surfaces, cell migration studies in 3D environment are still limited. To investigate cell migration und...

journal_title：Bioscience reports

authors： Hui J,Pang SW

更新日期：2019-02-19 00:00:00

abstract：:Extracorporeal pulsed electromagnetic field (PEMF) has shown the ability to regenerate tissue by promoting cell proliferation. In the present study, we investigated for the first time whether PEMF treatment could improve the myocardial ischaemia/reperfusion (I/R) injury and uncovered its underlying mechanisms.In our s...

journal_title：Bioscience reports

authors： Ma F,Li W,Li X,Tran BH,Suguro R,Guan R,Hou C,Wang H,Zhang A,Zhu Y,Zhu Y

更新日期：2016-12-05 00:00:00

abstract：:miRNAs have been implicated in processing of cardiac hypoxia/reoxygenation (H/R)-induced injury. Recent studies demonstrated that miR-19a might provide a potential cardioprotective effect on myocardial disease. However, the effect of miR-19a in regulating myocardial ischemic injury has not been previously addressed. T...

journal_title：Bioscience reports

authors： Sun G,Lu Y,Li Y,Mao J,Zhang J,Jin Y,Li Y,Sun Y,Liu L,Li L

更新日期：2017-12-05 00:00:00

abstract：:Aspergillus fumigatus is the causative agent of IA (invasive aspergillosis) in immunocompromised patients. It possesses a cell wall composed of chitin, glucan and galactomannan, polymeric carbohydrates synthesized by processive glycosyltransferases from intracellular sugar nucleotide donors. Here we demonstrate that A...

journal_title：Bioscience reports

authors： Fang W,Du T,Raimi OG,Hurtado-Guerrero R,Mariño K,Ibrahim AF,Albarbarawi O,Ferguson MA,Jin C,Van Aalten DM

更新日期：2013-09-04 00:00:00

abstract：:Huaier Granule, a type of traditional Chinese biomedical preparation (TCBP), is considered to be a promising adjuvant therapy for breast cancer. Although an analysis of the published literature has been performed, the exact effects and safety of Huaier Granule remains controversial. Therefore, a wide-ranging systemati...

journal_title：Bioscience reports

authors： Yao X,Wu W,Qu K,Xi W

更新日期：2020-08-28 00:00:00