Hydrophobic adhesin of E coli in ulcerative colitis.

Abstract:

:Pathogenic E coli have adhesive properties which are mirrored by an increase in their surface hydrophobicity. E coli isolated from patients with ulcerative colitis possess a mannose resistant adhesin similar to that found in pathogenic E coli. In this study 42 E coli isolates from patients with colitis have been compared with 15 from controls to assess hydrophobicity and cellular adherence. The salting out method and the buccal epithelial cell technique were used respectively. E coli isolated from colitics are significantly more hydrophobic than control E coli (p less than 0.001). The salting out score correlates negatively with the buccal epithelial cell adhesion index. When E coli are grown at 18 degrees C both properties are temporarily reduced suggesting that they are related to each other. The salting out method clearly differentiates between E coli isolated from colitics and controls, and offers a simple method of detecting adhesive E coli in inflammatory bowel disease.

journal_name

Gut

journal_title

Gut

authors

Burke DA,Axon AT

doi

10.1136/gut.29.1.41

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

41-3

issue

1

eissn

0017-5749

issn

1468-3288

journal_volume

29

pub_type

杂志文章

相关文献

GUT文献大全
  • Cell proliferation in Helicobacter pylori associated gastritis and the effect of eradication therapy.

    abstract::Helicobacter pylori causes chronic (type B) gastritis. The 'intestinal' form of gastric cancer arises against a background of chronic gastritis, and prospective epidemiological studies have shown that H pylori is a major risk factor for this. An increase in mucosal cell proliferation increases the likelihood of a neop...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.36.3.346

    authors: Lynch DA,Mapstone NP,Clarke AM,Sobala GM,Jackson P,Morrison L,Dixon MF,Quirke P,Axon AT

    更新日期:1995-03-01 00:00:00

  • Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals.

    abstract:BACKGROUND:In this study, we identify the nature of the immunological response of human peripheral blood mononuclear cells (PBMC) and lamina propria gastric lymphocytes (LPL) to two Helicobacter pylori antigens, the neutrophil activating protein (NapA) and alkyl hydroperoxide reductase (AphC). These antigens were ident...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2003.025494

    authors: Windle HJ,Ang YS,Athie-Morales V,McManus R,Kelleher D

    更新日期:2005-01-01 00:00:00

  • Enterochromaffin cell and 5-hydroxytryptamine responses to the same infectious agent differ in Th1 and Th2 dominant environments.

    abstract:BACKGROUND/AIM:5-Hydroxytryptamine (5-HT) released from enterochromaffin cells influences intestinal homeostasis by altering gut physiology and is implicated in the pathophysiology of various gut disorders. The mechanisms regulating 5-HT production in the gut remain unclear. This study investigated the T helper (Th) 1/...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2007.129296

    authors: Motomura Y,Ghia JE,Wang H,Akiho H,El-Sharkawy RT,Collins M,Wan Y,McLaughlin JT,Khan WI

    更新日期:2008-04-01 00:00:00

  • Pathophysiological relevance of apical large-conductance Ca²+-activated potassium channels in pancreatic duct epithelial cells.

    abstract:BACKGROUND:Acute pancreatitis is among the few inflammatory diseases for which no specific pharmacological treatment is available. It has previously been shown that bile acids alter pancreatic ductal secretion and these effects are probably involved in the pathogenesis of bile-induced pancreatitis. OBJECTIVE:To unders...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2010.214213

    authors: Venglovecz V,Hegyi P,Rakonczay Z Jr,Tiszlavicz L,Nardi A,Grunnet M,Gray MA

    更新日期:2011-03-01 00:00:00

  • Estimation of carcinoembryonic antigen in ulcerative colitis with special reference to malignant change.

    abstract::The levels of plasma carcinoembryonic antigen (CEA) were estimated in 59 control subjects attending St Mark's Hospital and in 139 patients with uncomplicated ulcerative colitis. There was little difference in the CEA levels in the two groups. In the colitic patients, the actual CEA values could not be correlated with ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.16.4.255

    authors: Dilawari JB,Lennard-Jones JE,Mackay AM,Ritchie JK,Sturzaker HG

    更新日期:1975-04-01 00:00:00

  • Bovine immunoglobulin concentrate-clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine.

    abstract:BACKGROUND:Bovine immunoglobulin concentrate (BIC)-Clostridium difficile is prepared from the colostrum of cows immunised against C difficile toxins and contains high concentrations of neutralising IgG antitoxin. AIMS:To determine the proportion of BIC-C difficile which survives passage through the human stomach and s...

    journal_title:Gut

    pub_type: 临床试验,杂志文章

    doi:10.1136/gut.44.2.212

    authors: Warny M,Fatimi A,Bostwick EF,Laine DC,Lebel F,LaMont JT,Pothoulakis C,Kelly CP

    更新日期:1999-02-01 00:00:00

  • Prolonged manometric recording of anorectal motor activity in ambulant human subjects: evidence of periodic activity.

    abstract::Based on short recordings, the rectum has been shown to have contractions with a frequency of five to 10 cycles per minute and slow contractions at three cycles per minute. To define anorectal motility over a prolonged period of time, we have studied 12 healthy volunteers using a fine pressure sensitive anorectal prob...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.30.7.1007

    authors: Kumar D,Williams NS,Waldron D,Wingate DL

    更新日期:1989-07-01 00:00:00

  • Persistent systemic inflammatory response after stent insertion in patients with malignant bile duct obstruction.

    abstract:BACKGROUND:Surgery in patients with malignant bile duct obstruction is associated with high postoperative morbidity and mortality. Tumour necrosis factor alpha (TNF-alpha) plays a key role in the pathogenesis of these complications. AIMS:To determine the effect of biliary drainage on plasma concentrations of TNF-alpha...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.42.4.555

    authors: Ballinger AB,Woolley JA,Ahmed M,Mulcahy H,Alstead EM,Landon J,Clark ML,Farthing MJ

    更新日期:1998-04-01 00:00:00

  • Effect of the immune modulating agents cyclophosphamide, methotrexate, hydrocortisone, and cyclosporin A on an animal model of granulomatous bowel disease.

    abstract::This study was undertaken to determine the effect of cyclophosphamide, methotrexate, hydrocortisone, and cyclosporin A on a model of granulomatous infiltration in the terminal ileum and draining lymph nodes of the guinea pig. Treatment groups of six animals were used and compared to untreated groups of 12. Epithelioid...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.31.6.674

    authors: Mitchell IC,Turk JL

    更新日期:1990-06-01 00:00:00

  • An investigation into the enzyme histochemistry of adenocarcinomas of human large intestine and of the transitional epithelium immediately adjacent to them.

    abstract::Histochemical enzymatic studies were performed on 30 freshly resected large bowel carcinomas, 30 samples of normal colonic epithelium, and six samples of the histologically normal epithelium (so-called transitional epithelium) immediately adjacent to a carcinoma. Five enzymes were studied: nicotine adenine dinucleotid...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.15.10.783

    authors: Marsden JR,Dawson IM

    更新日期:1974-10-01 00:00:00

  • Duodenal involvement in Schistosoma mansoni infection.

    abstract::Intestinal involvement in Schistosoma mansoni infection is usually confined to the ileum and colon. Duodenal infestation was diagnosed in a patient with recurrent schistosomiasis despite treatment who presented with a postoperative small bowel fistula. Duodenal schistosomiasis can be suspected on endoscopy, but must a...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.29.7.1011

    authors: Contractor QQ,Benson L,Schulz TB,Contractor TQ,Kasturi N

    更新日期:1988-07-01 00:00:00

  • Effect of sodium taurocholate on gastric secretion in patients with duodenal ulceration.

    abstract::The effect of sodium taurocholate instillation on the stimulated stomachs of patients with duodenal ulceration has been investigated. Instillation into the stomach of sodium taurocholate significantly reduced pentagastrin stimulated volume and outputs of both acid and sodium, with no change in the calculated volume of...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.24.1.28

    authors: Lewin MR,Pifano E,Daniel RD,Boulos PB,Clark CG

    更新日期:1983-01-01 00:00:00

  • AN ANTIBODY PRECIPITATING UREASE AND ITS POSSIBLE RELATION TO GASTRIC ULCER.

    abstract::An antibody precipitating urease was found in 171 out of 180 human sera. Data obtained on limited material (50 cases) suggest that the anti-urease titre is appreciably higher in the serum of patients suffering from gastric ulcer. This is a pointer towards a possible antigen-antibody mechanism in the genesis of chronic...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.4.4.339

    authors: FREISINGER FS

    更新日期:1963-12-01 00:00:00

  • Evaluation of indium scintigraphy in patients with active inflammatory bowel disease.

    abstract::Recent reports have indicated a possible role for 111Indium leucocyte scintigraphy in the management of patients with acute inflammatory bowel disease. Our experience with this technique in 15 patients (nine with ulcerative colitis, six with Crohn's disease) is described. Perfect agreement was not obtained between sci...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.25.12.1372

    authors: Buxton-Thomas MS,Dickinson RJ,Maltby P,Hunter JO,Wraight EP

    更新日期:1984-12-01 00:00:00

  • Augmentation effect of postprandial hyperinsulinaemia on growth of human hepatocellular carcinoma.

    abstract:BACKGROUND:Cirrhotic patients with hepatocellular carcinoma (HCC) frequently have impaired glucose metabolism. AIMS:To investigate whether impaired glucose metabolism affects the growth rate of the tumour. PATIENTS AND METHODS:Tumour doubling time (DT), assessed by ultrasound imaging analysis, was measured in 60 pati...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.51.1.100

    authors: Saito K,Inoue S,Saito T,Kiso S,Ito N,Tamura S,Watanabe H,Takeda H,Misawa H,Togashi H,Matsuzawa Y,Kawata S

    更新日期:2002-07-01 00:00:00

  • The applicability of hepatocellular carcinoma risk prediction scores in a North American patient population with chronic hepatitis B infection.

    abstract:BACKGROUND:Patients with chronic hepatitis B (CHB) infection are at an increased risk of developing hepatocellular carcinoma (HCC). Risk scores have been developed in Asian populations to predict HCC risk over time. AIM:To assess the performance of HCC risk prediction models in a heterogeneous population of patients w...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gutjnl-2014-309099

    authors: Abu-Amara M,Cerocchi O,Malhi G,Sharma S,Yim C,Shah H,Wong DK,Janssen HL,Feld JJ

    更新日期:2016-08-01 00:00:00

  • Detection of Helicobacter pylori infection of the gastric mucosa by measurement of gastric aspirate ammonium and urea concentrations.

    abstract::Helicobacter pylori possesses unusually high urease activity that lowers the urea concentration and raises the ammonium concentration of the gastric juice in infected people. The value of measuring urea and ammonium concentrations in gastric juice obtained during upper gastrointestinal endoscopy as a means of diagnosi...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.32.9.973

    authors: Neithercut WD,Milne A,Chittajallu RS,el Nujumi AM,McColl KE

    更新日期:1991-09-01 00:00:00

  • Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.

    abstract:BACKGROUND AND AIMS:Insulin-like growth factor (IGF) I receptor (IGF-Ir) signalling is required for carcinogenicity and proliferation of many tumours but this pathway has not been studied in detail in gastric cancer. We have previously shown successful therapy for colorectal, pancreatic, and lung cancer using recombina...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2004.048926

    authors: Min Y,Adachi Y,Yamamoto H,Imsumran A,Arimura Y,Endo T,Hinoda Y,Lee CT,Nadaf S,Carbone DP,Imai K

    更新日期:2005-05-01 00:00:00

  • Intercellular adhesion molecule-1 and MHC antigens on human intrahepatic bile duct cells: effect of pro-inflammatory cytokines.

    abstract::Human intrahepatic biliary epithelial cells were isolated from the livers of patients with primary biliary cirrhosis and from normal livers and established in primary culture. The in vitro expression of intercellular adhesion molecule-1, HLA class I, and HLA class II on biliary epithelial cells was studied in response...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.34.9.1245

    authors: Ayres RC,Neuberger JM,Shaw J,Joplin R,Adams DH

    更新日期:1993-09-01 00:00:00

  • Antibodies to carbonic anhydrase and IgG4 levels in idiopathic chronic pancreatitis: relevance for diagnosis of autoimmune pancreatitis.

    abstract:BACKGROUND:Increased serum antibodies against carbonic anhydrase II (CA-II Ab) or IgG4 levels have been reported in cases of autoimmune chronic pancreatitis (ACP). AIM:To assess the relevance of serum CA-II Ab and IgG4 levels for the diagnosis of ACP in idiopathic CP (ICP) versus alcoholic CP and Sjogren's syndrome (S...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究

    doi:10.1136/gut.2004.047142

    authors: Aparisi L,Farre A,Gomez-Cambronero L,Martinez J,De Las Heras G,Corts J,Navarro S,Mora J,Lopez-Hoyos M,Sabater L,Ferrandez A,Bautista D,Perez-Mateo M,Mery S,Sastre J

    更新日期:2005-05-01 00:00:00

  • Incidence and management of malignant digestive endocrine tumours in a well defined French population.

    abstract:BACKGROUND AND AIMS:Little is known about the epidemiology of malignant digestive endocrine tumours. The aim of this study was to report on their incidence and management in a well defined population. METHODS:Data were obtained from the population based Digestive Cancer Registry of Burgundy (France) over a 24 year per...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.2003.026401

    authors: Lepage C,Bouvier AM,Phelip JM,Hatem C,Vernet C,Faivre J

    更新日期:2004-04-01 00:00:00

  • Bone histomorphometry and structure in corticosteroid treated chronic active hepatitis.

    abstract::Transiliac biopsies from 34 female patients with corticosteroid treated chronic active hepatitis have been examined to determine the contributions made by decreased bone formation and increased bone resorption to bone loss associated with this condition and to determine the structural basis of the bone loss. Mean wall...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.29.3.378

    authors: Stellon AJ,Webb A,Compston JE

    更新日期:1988-03-01 00:00:00

  • Effects of phenobarbital and rose bengal on the ATPases of plasma membranes of rat and rabbit liver.

    abstract::The effects of drugs which change the bile-salt-independent fraction of bile flow on Na(+)K(a+) and Mg(2+) activated ATPases were studied in membrane fractions rich in bile canaliculi. The administration of phenobarbital caused no induction of these enzymes which could explain the increased bile flow observed in the r...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.13.11.920

    authors: Laperche Y,Launay A,Oudéa P

    更新日期:1972-11-01 00:00:00

  • Influence of dehydrocholate and taurocholate on bromsulphthalein uptake, storage, and excretion in the dog.

    abstract::The influence of dehydrocholate on bromsulphtalein relative-storage capacity, bilary transport maximum (Tm), and fractional transfer rates between plasma, liver and bile have been studied in unanaesthetized dogs. In six dogs, storage capacity, Tm, and fractional transfer rates from plasma to liver, liver to bile, and ...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.16.2.105

    authors: Delage Y,Erlinger S,Duval M,Bpenhamou JP

    更新日期:1975-02-01 00:00:00

  • Proliferation cell nuclear antigen (clone 19A2) correlates with 5-bromo-2-deoxyuridine labelling in human colonic epithelium.

    abstract::Measurements of cell proliferation can be used as biomarkers of preneoplastic change. In this study, two immunocytochemical methods that measure different components of the cell cycle were compared to assess cell proliferation on biopsy samples from human colonic mucosa. These methods are based on a monoclonal antibod...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.34.11.1587

    authors: Weisgerber UM,Boeing H,Nemitz R,Raedsch R,Waldherr R

    更新日期:1993-11-01 00:00:00

  • A prospective controlled study comparing brush and bile exfoliative cytology for diagnosing bile duct strictures.

    abstract::Imaging of biliary strictures may suggest malignancy but cytology can provide a tissue diagnosis. The aim of this study is to compare the diagnostic value of brush cytology and bile cytology. Thirty two patients (20 males, 12 females, median age 66 years, range 31-84) with biliary strictures at endoscopic retrograde c...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.33.12.1675

    authors: Kurzawinski T,Deery A,Dooley J,Dick R,Hobbs K,Davidson B

    更新日期:1992-12-01 00:00:00

  • Effect of ICS 205-930 (a specific 5-HT3 receptor antagonist) on gastric emptying of a solid meal in normal subjects.

    abstract::The effects on gastric emptying of a solid meal of the specific 5-HT3-receptor antagonist ICS 205-930, 10 mg and 20 mg intravenously were assessed with a scintigraphic technique in 12 normals. The 50% emptying time was less, the lag phase was shorter and the post lag emptying rate was faster after 20 mg ICS 205-930 (p...

    journal_title:Gut

    pub_type: 临床试验,杂志文章

    doi:10.1136/gut.29.9.1249

    authors: Akkermans LM,Vos A,Hoekstra A,Roelofs JM,Horowitz M

    更新日期:1988-09-01 00:00:00

  • Hepatitis C virus: epidemiology and genotypes in the north east of England.

    abstract::The epidemiology of hepatitis C virus (HCV) infection was studied in an English teaching hospital over an 18 month period. A total of 104 HCV antibody positive patients were referred for further investigation. They were divided into those diagnosed through screening (blood donors and intravenous drug abusers) and thos...

    journal_title:Gut

    pub_type: 杂志文章

    doi:10.1136/gut.38.2.269

    authors: Watson JP,Brind AM,Chapman CE,Bates CL,Gould FK,Johnson SJ,Burt AD,Ferguson J,Simmonds P,Bassendine MF

    更新日期:1996-02-01 00:00:00

  • Undiagnosed coeliac disease does not appear to be associated with unfavourable outcome of pregnancy.

    abstract:BACKGROUND:In a previous hospital based study, we suggested that undiagnosed coeliac disease has a prevalence, among pregnant women, of 1:80, and is a cause of unfavourable outcome of pregnancy. AIMS:In order to confirm or dismiss this hypothesis, which has significant public health implications, we carried out a larg...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究

    doi:10.1136/gut.53.1.149

    authors: Greco L,Veneziano A,Di Donato L,Zampella C,Pecoraro M,Paladini D,Paparo F,Vollaro A,Martinelli P

    更新日期:2004-01-01 00:00:00

  • Infliximab for the treatment of pyoderma gangrenosum: a randomised, double blind, placebo controlled trial.

    abstract:BACKGROUND:Pyoderma gangrenosum (PG) is a chronic ulcerating skin condition that often occurs in association with inflammatory bowel disease. There have been a number of reports of PG responding to infliximab, a monoclonal antibody against tumour necrosis factor alpha. AIM:In the first randomised placebo controlled tr...

    journal_title:Gut

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1136/gut.2005.074815

    authors: Brooklyn TN,Dunnill MG,Shetty A,Bowden JJ,Williams JD,Griffiths CE,Forbes A,Greenwood R,Probert CS

    更新日期:2006-04-01 00:00:00