Abstract：
:Obesity is associated with a high prevalence of mood disorders such as anxiety and depression. Both stress and high fat diet can alter the gut microbiota and contribute to obesity. To examine the interrelationships between obesity, stress, gut microbiota and mood disorders, obesity was induced in mice using a high fat diet, and the mice were subsequently stressed using a chronic unpredictable mild stress protocol. During the experiment, the composition of the gut microbiota was analyzed by 16 S rRNA gene high-throughput sequencing, and anxiety-like behaviors were measured. The results revealed distinct gender differences in the impacts of obesity and stress on anxiety-like behaviors, activity levels, and composition of the gut microbiota. Male mice were more vulnerable to the anxiogenic effects of the high fat diet, and obese male mice showed decreased locomotion activity in response to stress whereas obese female mice did not. In females, stress caused the gut microbiota of lean mice to more closely resemble that of obese mice. Taken together, these results suggest the importance of considering gender as a biological variable in studies on the role of gut microbiota in obesity-related mood disorders.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Bridgewater LC,Zhang C,Wu Y,Hu W,Zhang Q,Wang J,Li S,Zhao Ldoi
10.1038/s41598-017-11069-4subject
Has Abstractpub_date
2017-09-07 00:00:00pages
10776issue
1issn
2045-2322pii
10.1038/s41598-017-11069-4journal_volume
7pub_type
杂志文章abstract：:Graphene, a two-dimensional structure of carbon, due to its structure has unique physico-chemical properties that can be used in numerous research and industry areas. Although this structure is already well known, there are still technological (and cost) barriers which do not allow to produce this material in large qu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67977-5
更新日期：2020-07-06 00:00:00
abstract：:During maternal recognition of pregnancy (MRP), a conceptus-derived signal leads to the persistence of the corpus luteum and the maintenance of gestation. In the horse, the nature of this signal remains to be elucidated. Several studies have focused on the changes in gene expression during MRP, but little information ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23537-6
更新日期：2018-03-27 00:00:00
abstract：:Silver nanoparticles (AgNPs) have been extensively used and are considered as an emerging contaminant in the ocean. The environmental contamination of AgNPs is expected to increase greatly over time, and cetaceans, as the top ocean predators, will suffer the negative impacts of AgNPs. In the present study, we investig...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23737-0
更新日期：2018-04-04 00:00:00
abstract：:The negatively charged nitrogen-vacancy ([Formula: see text]) center shows excellent spin properties and sensing capabilities on the nanoscale even at room temperature. Shallow implanted [Formula: see text] centers can effectively be protected from surface noise by chemical vapor deposition (CVD) diamond overgrowth, i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79943-2
更新日期：2020-12-29 00:00:00
abstract：:Climate change is the greatest threat to coral reef ecosystems. In particular, increasing ocean temperatures are causing severe and widespread coral bleaching, contributing to extensive coral loss and degradation of coral reef habitats globally. Effects of coral bleaching are not however, equally apportioned among dif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44809-9
更新日期：2019-06-10 00:00:00
abstract：:Melanoma patients' plasma contains exosomes produced by malignant and normal cells. Plasma exosomes were isolated and separated by immunocapture into two fractions: melanoma cell-derived exosomes (MTEX) and normal cell-derived exosomes (non-MTEX). Immunosuppressive effects of MTEX on primary human immune cells were ev...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56542-4
更新日期：2020-01-09 00:00:00
abstract：:The anhydrofructose pathway is an alternate pathway for glycogen degradation by α-1,4-glucan lyase. The sugar 1,5-anhydro-D-fructose (1,5-AF) acts as the central intermediate of this pathway, but its physiological role of in mammals is unclear. Glycation reactions forming advanced glycation end-products (AGEs) are imp...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46333-2
更新日期：2019-07-15 00:00:00
abstract：:Honey bees (Apis mellifera) are important pollinators and their health is threatened worldwide by persistent exposure to a wide range of factors including pesticides, poor nutrition, and pathogens. Nosema ceranae is a ubiquitous microsporidian associated with high colony mortality. We used lab micro-colonies of honey ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep22042
更新日期：2016-02-25 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-67913-7
更新日期：2020-06-30 00:00:00
abstract：:In situ measurements by the Curiosity rover provide a unique opportunity for studying the effects of dust on assets placed at the surface of Mars. Here we use in situ measurements of solar UV radiation to quantify the seasonal and interannual variability of dust accumulation on the sensor on the rover deck. We show th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35946-8
更新日期：2018-12-04 00:00:00
abstract：:High throughput sequencing techniques are poorly adapted for in vivo studies of parasites, which require prior in vitro culturing and purification. Trypanosomatids, a group of kinetoplastid protozoans, possess a distinctive feature in their transcriptional mechanism whereby a specific Spliced Leader (SL) sequence is a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03987-0
更新日期：2017-06-16 00:00:00
abstract：:Anthurium amnicola Dressler possesses a number of desirable and novel ornamental traits such as a purple-colored upright spathe, profuse flowering, and floral scent, some of which have been introgressed into modern Anthurium cultivars. As a first step in identifying genes associated with these traits, the transcriptom...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00808-2
更新日期：2017-05-04 00:00:00
abstract：:Rice bacterial blight caused by Xanthomonas oryzae pv. oryzae (Xoo) is one of the most destructive rice diseases worldwide. Therefore, in addition to breeding disease-resistant rice cultivars, it is desirable to develop effective biocontrol agents against Xoo. Here, we report that a soil bacterium Pseudomonas taiwanen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep32950
更新日期：2016-09-08 00:00:00
abstract：:Shiga toxin-producing Escherichia coli (STEC) is an important foodborne pathogen. The increasing incidence of non-O157 STEC has posed a great risk to public health. Besides the Shiga toxin (Stx), the adherence factor, intimin, coded by eae gene plays a critical role in STEC pathogenesis. In this study, we investigated...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60225-w
更新日期：2020-02-24 00:00:00
abstract：:We aimed to report patients' survival after surgical resection of eSCC and to ascertain the clinical, imaging, and pathological factors related to patient prognosis. This retrospective study included 435 patients with eSCC of journal_title：Scientific reports pub_type： 杂志文章 doi：10.1038/s41598-020-62028-5 更新日期：2020-03-19 00:00:00
abstract：:Ants are a dominant insect group in terrestrial ecosystems and many myrmecophilous species evolve to associate with ants to gain benefits. One iconic example is myrmecophilous butterflies that often produce ant-mimicking vibrational calls to modulate ant behaviors. Despite its popularity, empirical exploration of how ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54966-6
更新日期：2019-12-06 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-63126-0
更新日期：2020-04-20 00:00:00
abstract：:The recombination is one of the most frequently identified drivers of double-stranded DNA viruses evolution. However, the recombination events in African swine fever virus (ASFV) genomes have been poorly annotated. We hypothesize that the genetic determinants of ASFV variability are potential hot-spots for recombinati...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75377-y
更新日期：2020-10-28 00:00:00
abstract：:Porphyry deposits are copper-rich orebodies formed by precipitation of metal sulphides from hydrothermal fluids released from magmatic intrusions that cooled at depth within the Earth's crust. Finding new porphyry deposits is essential because they are our largest source of copper and they also contain other strategic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40566
更新日期：2017-01-12 00:00:00
abstract：:We investigated the metabolic outcome of different coping strategies in 129S6/SvEvTac (129Sv) and C57BL/6Ntac (Bl6) strains. Two different batches of male 129Sv and Bl6 mice were used. One batch was not subjected to any behavioral manipulations (home cage control; HCC), whereas the other batch was treated with saline ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-21752-9
更新日期：2018-02-21 00:00:00
abstract：:The Toarcian Oceanic Anoxic Event (TOAE, Early Jurassic, ~182 Ma ago) was characterised by severe environmental perturbations which led to habitat degradation and extinction of marine species. Warming-induced anoxia is usually identified as main driver, but because marine life was also affected in oxygenated environme...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-61393-5
更新日期：2020-03-13 00:00:00
abstract：:Studies have reported that neck and/or shoulder pain (NSP) was prevalent and a non-ignorable occupational health problem in healthcare providers. Considering data deficiency on NSP, we aimed to investigate the prevalence and sick leave absence of NSP among public hospital workers in Shandong, China and to explore the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69382-4
更新日期：2020-07-23 00:00:00
abstract：:We developed a reporter system that can be used in a dual manner in visualizing mature osteoblast formation. The system is based on a helper-dependent adenoviral vector (HDAdV), in which a fluorescent protein, Venus, is expressed under the control of the 19-kb human osteocalcin (OC) genomic locus. By infecting human a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46105-y
更新日期：2019-07-04 00:00:00
abstract：:The endoplasmic reticulum (ER) is the main site of protein synthesis in eukaryotic cells and requires a high concentration of luminal chaperones to function. During protein synthesis, ER luminal chaperones are swept along the secretory pathway and must be retrieved to maintain cell viability. ER protein retrieval is a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73906-3
更新日期：2020-10-09 00:00:00
abstract：:To achieve a better understanding of the "vinegar syndrome" phenomenon, which has caused serious damage to triacetyl cellulose-based motion picture films, the white powder obtained from damaged film surfaces was analysed in this study. The powder was found to be soluble in acetone, diethyl ether, dimethylformamide, an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80498-5
更新日期：2021-01-15 00:00:00
abstract：:All solid-state lithium-ion transistors are considered as promising synaptic devices for building artificial neural networks for neuromorphic computing. However, the slow ionic conduction in existing electrolytes hinders the performance of lithium-ion-based synaptic transistors. In this study, we systematically explor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55310-8
更新日期：2019-12-11 00:00:00
abstract：:The temporal structure of sound such as in music and speech increases the efficiency of auditory processing by providing listeners with a predictable context. Musical meter is a good example of a sound structure that is temporally organized in a hierarchical manner, with recent studies showing that meter optimizes neu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72714-z
更新日期：2020-09-29 00:00:00
abstract：:In this study, we identified a CD105+CD90.1-CD133-CD55- (CD133-CD55-) population in the fetal skeletal element that can generate bone and bone marrow. Besides osteoblasts and chondrocytes, the CD133-CD55- common progenitors can give rise to marrow reticular stromal cells and perivascular mesenchymal progenitors sugges...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38632
更新日期：2016-12-08 00:00:00
abstract：:The temperature dependence of the resistivity (ρ) of Ag-doped Bi2Se3 (AgxBi2-xSe3) shows insulating behavior above 35 K, but below 35 K, ρ suddenly decreases with decreasing temperature, in contrast to the metallic behavior for non-doped Bi2Se3 at 1.5-300 K. This significant change in transport properties from metalli...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41906-7
更新日期：2019-03-29 00:00:00
abstract：:Oxidative stress and mitochondrial dysfunction have been associated with metabolic and age-related diseases. Thus, the prevention of mitochondrial oxidative damage is nowadays a recognized pharmacological strategy to delay disease progression. Epidemiological studies suggested an association between the consumption of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07272-y
更新日期：2017-07-28 00:00:00
