Alkaline earth metal vanadates as sodium-ion battery anodes.

abstract：:Human APOBEC3A (A3A) cytidine deaminase is a host enzyme that can introduce mutations into chromosomal DNA. As APOBEC3B (A3B) encodes a C-terminal catalytic domain ~91% identical to A3A, we examined its genotoxic potential as well as that of a highly prevalent chimaeric A3A-A3B deletion allele (ΔA3B), which is linked ...

journal_title：Nature communications

authors： Caval V,Suspène R,Shapira M,Vartanian JP,Wain-Hobson S

更新日期：2014-10-09 00:00:00

abstract：:Blood vessels in the central nervous system (CNS) develop unique features, but the contribution of CNS neurons to regulating those features is not fully understood. We report that inhibiting spontaneous cholinergic activity or reducing starburst amacrine cell numbers prevents invasion of endothelial cells into the dee...

journal_title：Nature communications

authors： Weiner GA,Shah SH,Angelopoulos CM,Bartakova AB,Pulido RS,Murphy A,Nudleman E,Daneman R,Goldberg JL

更新日期：2019-06-06 00:00:00

abstract：:Multifactorial mechanisms underlying late-onset Alzheimer's disease (LOAD) are poorly characterized from an integrative perspective. Here spatiotemporal alterations in brain amyloid-β deposition, metabolism, vascular, functional activity at rest, structural properties, cognitive integrity and peripheral proteins level...

journal_title：Nature communications

authors： Iturria-Medina Y,Sotero RC,Toussaint PJ,Mateos-Pérez JM,Evans AC,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2016-06-21 00:00:00

abstract：:The mega-diversity of herbivorous insects is attributed to their co-evolutionary associations with plants. Despite abundant studies on insect-plant interactions, we do not know whether host-plant shifts have impacted both genomic adaptation and species diversification over geological times. We show that the antagonist...

journal_title：Nature communications

authors： Allio R,Nabholz B,Wanke S,Chomicki G,Pérez-Escobar OA,Cotton AM,Clamens AL,Kergoat GJ,Sperling FAH,Condamine FL

更新日期：2021-01-13 00:00:00

abstract：:The HIV Tat protein competes with the 7SK:HEXIM interaction to hijack pTEFb from 7SK snRNP and recruit it to the TAR motif on stalled viral transcripts. Here we solve structures of 7SK stemloop-1 and TAR in complex with Tat's RNA binding domain (RBD) to gain insights into this process. We find that 7SK is peppered wit...

journal_title：Nature communications

authors： Pham VV,Salguero C,Khan SN,Meagher JL,Brown WC,Humbert N,de Rocquigny H,Smith JL,D'Souza VM

更新日期：2018-10-15 00:00:00

abstract：:Voltage-gated sodium channels (Na(v)) underlie the rapid upstroke of action potentials in excitable tissues. Binding of channel-interactive proteins is essential for controlling fast and long-term inactivation. In the structure of the complex of the carboxy-terminal portion of Na(v)1.5 (CTNa(v)1.5) with calmodulin (Ca...

journal_title：Nature communications

authors： Gabelli SB,Boto A,Kuhns VH,Bianchet MA,Farinelli F,Aripirala S,Yoder J,Jakoncic J,Tomaselli GF,Amzel LM

更新日期：2014-11-05 00:00:00

abstract：:Building a population-specific catalogue of single nucleotide variants (SNVs), indels and structural variants (SVs) with frequencies, termed a national pan-genome, is critical for further advancing clinical and public health genetics in large cohorts. Here we report a Danish pan-genome obtained from sequencing 10 trio...

journal_title：Nature communications

authors： Besenbacher S,Liu S,Izarzugaza JM,Grove J,Belling K,Bork-Jensen J,Huang S,Als TD,Li S,Yadav R,Rubio-García A,Lescai F,Demontis D,Rao J,Ye W,Mailund T,Friborg RM,Pedersen CN,Xu R,Sun J,Liu H,Wang O,Cheng X,Fl

更新日期：2015-01-19 00:00:00

abstract：:Soliton microcombs constitute chip-scale optical frequency combs, and have the potential to impact a myriad of applications from frequency synthesis and telecommunications to astronomy. The demonstration of soliton formation via self-injection locking of the pump laser to the microresonator has significantly relaxed t...

journal_title：Nature communications

authors： Voloshin AS,Kondratiev NM,Lihachev GV,Liu J,Lobanov VE,Dmitriev NY,Weng W,Kippenberg TJ,Bilenko IA

更新日期：2021-01-11 00:00:00

abstract：:Despite compelling antitumour activity of antibodies targeting the programmed death 1 (PD-1): programmed death ligand 1 (PD-L1) immune checkpoint in lung cancer, resistance to these therapies has increasingly been observed. In this study, to elucidate mechanisms of adaptive resistance, we analyse the tumour immune mic...

journal_title：Nature communications

authors： Koyama S,Akbay EA,Li YY,Herter-Sprie GS,Buczkowski KA,Richards WG,Gandhi L,Redig AJ,Rodig SJ,Asahina H,Jones RE,Kulkarni MM,Kuraguchi M,Palakurthi S,Fecci PE,Johnson BE,Janne PA,Engelman JA,Gangadharan SP,Costa DB,

更新日期：2016-02-17 00:00:00

abstract：:The generation of temporal cavity solitons in microresonators results in coherent low-noise optical frequency combs that are critical for applications in spectroscopy, astronomy, navigation or telecommunications. Breather solitons also form an important part of many different classes of nonlinear wave systems, manifes...

journal_title：Nature communications

authors： Yu M,Jang JK,Okawachi Y,Griffith AG,Luke K,Miller SA,Ji X,Lipson M,Gaeta AL

更新日期：2017-02-24 00:00:00

abstract：:Electric gating can strongly modulate a wide variety of physical properties in semiconductors and insulators, such as significant changes of conductivity in silicon, appearance of superconductivity in SrTiO3, the paramagnet-ferromagnet transition in (In,Mn)As, and so on. The key to such modulation is charge accumulati...

journal_title：Nature communications

authors： Dushenko S,Hokazono M,Nakamura K,Ando Y,Shinjo T,Shiraishi M

更新日期：2018-08-07 00:00:00

abstract：:Previous research has focused on feeding circuits residing in the hindbrain and midbrain that govern homeostatic or hedonic control of food intake. However, the feeding circuits controlling emotional or cognitive aspects of food intake are largely unknown. Here we use chemical genetics and optogenetic techniques to di...

journal_title：Nature communications

authors： Sweeney P,Yang Y

更新日期：2015-12-15 00:00:00

abstract：:Acute kidney injury (AKI) is considered largely reversible based on the capacity of surviving tubular cells to dedifferentiate and replace lost cells via cell division. Here we show by tracking individual tubular cells in conditional Pax8/Confetti mice that kidney function is  recovered after AKI despite substantial t...

journal_title：Nature communications

authors： Lazzeri E,Angelotti ML,Peired A,Conte C,Marschner JA,Maggi L,Mazzinghi B,Lombardi D,Melica ME,Nardi S,Ronconi E,Sisti A,Antonelli G,Becherucci F,De Chiara L,Guevara RR,Burger A,Schaefer B,Annunziato F,Anders HJ,La

更新日期：2018-04-09 00:00:00

abstract：:Magnetized plasma interactions are ubiquitous in astrophysical and laboratory plasmas. Various physical effects have been shown to be important within colliding plasma flows influenced by opposing magnetic fields, however, experimental verification of the mechanisms within the interaction region has remained elusive. ...

journal_title：Nature communications

authors： Tubman ER,Joglekar AS,Bott AFA,Borghesi M,Coleman B,Cooper G,Danson CN,Durey P,Foster JM,Graham P,Gregori G,Gumbrell ET,Hill MP,Hodge T,Kar S,Kingham RJ,Read M,Ridgers CP,Skidmore J,Spindloe C,Thomas AGR,Treadwe

更新日期：2021-01-12 00:00:00

abstract：:Iron chelators have been widely used to remove excess toxic iron from patients with secondary iron overload. However, small molecule-based iron chelators can cause adverse side effects such as infection, gastrointestinal bleeding, kidney failure, and liver fibrosis. Here we report renal clearable nanochelators for iro...

journal_title：Nature communications

authors： Kang H,Han M,Xue J,Baek Y,Chang J,Hu S,Nam H,Jo MJ,El Fakhri G,Hutchens MP,Choi HS,Kim J

更新日期：2019-11-13 00:00:00

abstract：:Obesity develops when energy intake exceeds energy expenditure. Promoting brown adipose tissue formation and function increases energy expenditure and hence may counteract obesity. Berberine (BBR) is a compound derived from the Chinese medicinal plant Coptis chinensis. Here we show that BBR increases energy expenditur...

journal_title：Nature communications

authors： Zhang Z,Zhang H,Li B,Meng X,Wang J,Zhang Y,Yao S,Ma Q,Jin L,Yang J,Wang W,Ning G

更新日期：2014-11-25 00:00:00

abstract：:Unusual features of the vibrational density of states D(ω) of glasses allow one to rationalize their peculiar low-temperature properties. Simulational studies of D(ω) have been restricted to studying poorly annealed glasses that may not be relevant to experiments. Here we report on D(ω) of zero-temperature glasses wit...

journal_title：Nature communications

authors： Wang L,Ninarello A,Guan P,Berthier L,Szamel G,Flenner E

更新日期：2019-01-03 00:00:00

abstract：:In healthy blood vessels with a laminar blood flow, the endothelial cell division rate is low, only sufficient to replace apoptotic cells. The division rate significantly increases during embryonic development and under halted or turbulent flow. Cells in barrier tissue are connected and their motility is highly correl...

journal_title：Nature communications

authors： Rossen NS,Tarp JM,Mathiesen J,Jensen MH,Oddershede LB

更新日期：2014-12-08 00:00:00

abstract：:Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system. They are derived from differentiation of oligodendrocyte progenitors through a process requiring cell cycle exit and histone modifications. Here we identify the histone arginine methyl-transferase PRMT5, a molecule catalyzing symmetric ...

journal_title：Nature communications

authors： Scaglione A,Patzig J,Liang J,Frawley R,Bok J,Mela A,Yattah C,Zhang J,Teo SX,Zhou T,Chen S,Bernstein E,Canoll P,Guccione E,Casaccia P

更新日期：2018-07-19 00:00:00

abstract：:The recent discovery of high-temperature superconductivity in iron-based compounds has attracted much attention. How to further increase the superconducting transition temperature (T(c)) and how to understand the superconductivity mechanism are two prominent issues facing the current study of iron-based superconductor...

journal_title：Nature communications

authors： Liu D,Zhang W,Mou D,He J,Ou YB,Wang QY,Li Z,Wang L,Zhao L,He S,Peng Y,Liu X,Chen C,Yu L,Liu G,Dong X,Zhang J,Chen C,Xu Z,Hu J,Chen X,Ma X,Xue Q,Zhou XJ

更新日期：2012-07-03 00:00:00

abstract：:Multi-layer structure of functional materials often involves the integration of different crystalline phases. The film growth orientation thus frequently exhibits a transformation, owing to multiple possibilities caused by incompatible in-plane structural symmetry. Nevertheless, the detailed mechanism of the transform...

journal_title：Nature communications

authors： Zhou H,Wu L,Wang HQ,Zheng JC,Zhang L,Kisslinger K,Li Y,Wang Z,Cheng H,Ke S,Li Y,Kang J,Zhu Y

更新日期：2017-11-14 00:00:00

abstract：:Supersymmetry is a conjectured symmetry between bosons and fermions aiming at solving fundamental questions in string and quantum field theory. Its subsequent application to quantum mechanics led to a ground-breaking analysis and design machinery, later fruitfully extrapolated to photonics. In all cases, the algebraic...

journal_title：Nature communications

authors： García-Meca C,Ortiz AM,Sáez RL

更新日期：2020-02-10 00:00:00

abstract：:Intestinal intraepithelial T cells contribute to the regulation of inflammatory responses in the intestine; however, the molecular basis for their development and maintenance is unknown. The aryl hydrocarbon receptor complexes with the aryl hydrocarbon receptor nuclear translocator (ARNT) and senses environmental fact...

journal_title：Nature communications

authors： Nakajima K,Maekawa Y,Kataoka K,Ishifune C,Nishida J,Arimochi H,Kitamura A,Yoshimoto T,Tomita S,Nagahiro S,Yasutomo K

更新日期：2013-01-01 00:00:00

abstract：:Most motile bacteria navigate within gradients of external chemical stimuli by regulating the length of randomly oriented swimming episodes. Magnetotactic bacteria are characterized by chains of intracellular ferromagnetic nanoparticles and their ability to sense the geomagnetic field, which is believed to facilitate ...

journal_title：Nature communications

authors： Popp F,Armitage JP,Schüler D

更新日期：2014-11-14 00:00:00

abstract：:It is commonly assumed that neural systems efficiently process natural sensory input. However, the mechanisms by which such efficient processing is achieved, and the consequences for perception and behaviour remain poorly understood. Here we show that small conductance calcium-activated potassium (SK) channels enable ...

journal_title：Nature communications

authors： Huang CG,Zhang ZD,Chacron MJ

更新日期：2016-04-18 00:00:00

abstract：:The reconstruction of human-driven, Earth-shaping dynamics is important for understanding past human/environment interactions and for helping human societies that currently face global changes. However, it is often challenging to distinguish the effects of the climate from human activities on environmental changes. He...

journal_title：Nature communications

authors： Giguet-Covex C,Pansu J,Arnaud F,Rey PJ,Griggo C,Gielly L,Domaizon I,Coissac E,David F,Choler P,Poulenard J,Taberlet P

更新日期：2014-01-01 00:00:00

abstract：:Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of ...

journal_title：Nature communications

authors： Chacón-Duque JC,Adhikari K,Fuentes-Guajardo M,Mendoza-Revilla J,Acuña-Alonzo V,Barquera R,Quinto-Sánchez M,Gómez-Valdés J,Everardo Martínez P,Villamil-Ramírez H,Hünemeier T,Ramallo V,Silva de Cerqueira CC,Hurtado M,Villegas V

更新日期：2018-12-19 00:00:00

abstract：:An effective way to improve polymer solar cell efficiency is to use a tandem structure, as a broader part of the spectrum of solar radiation is used and the thermalization loss of photon energy is minimized. In the past, the lack of high-performance low-bandgap polymers was the major limiting factor for achieving high...

journal_title：Nature communications

authors： You J,Dou L,Yoshimura K,Kato T,Ohya K,Moriarty T,Emery K,Chen CC,Gao J,Li G,Yang Y

更新日期：2013-01-01 00:00:00

abstract：:ADAM17, a prominent member of the 'Disintegrin and Metalloproteinase' (ADAM) family, controls vital cellular functions through cleavage of transmembrane substrates. Here we present evidence that surface exposure of phosphatidylserine (PS) is pivotal for ADAM17 to exert sheddase activity. PS exposure is tightly coupled...

journal_title：Nature communications

authors： Sommer A,Kordowski F,Büch J,Maretzky T,Evers A,Andrä J,Düsterhöft S,Michalek M,Lorenzen I,Somasundaram P,Tholey A,Sönnichsen FD,Kunzelmann K,Heinbockel L,Nehls C,Gutsmann T,Grötzinger J,Bhakdi S,Reiss K

更新日期：2016-05-10 00:00:00

abstract：:Simultaneous deep brain stimulation (DBS) and functional magnetic resonance imaging (fMRI) constitutes a powerful tool for elucidating brain functional connectivity, and exploring neuromodulatory mechanisms of DBS therapies. Previous DBS-fMRI studies could not provide full activation pattern maps due to poor MRI compa...

journal_title：Nature communications

authors： Zhao S,Li G,Tong C,Chen W,Wang P,Dai J,Fu X,Xu Z,Liu X,Lu L,Liang Z,Duan X

更新日期：2020-04-14 00:00:00