First-trimester placental thickness and the risk of preeclampsia or SGA.

abstract：:Intra-uterine growth restriction (IUGR) is defined by a restriction of fetal growth during gestation. It is a prevalent significant public health problem that jeopardizes neonatal health but also that can have deleterious consequences later in adult life. Cullins constitute a family of seven proteins involved in cell ...

journal_title：Placenta

authors： Gascoin-Lachambre G,Buffat C,Rebourcet R,Chelbi ST,Rigourd V,Mondon F,Mignot TM,Legras E,Simeoni U,Vaiman D,Barbaux S

更新日期：2010-02-01 00:00:00

abstract：:Placenta accreta is a pregnancy complication characterized by the presence of life-threatening uteroplacental neovascularization. The factors involving its development are unknown. Vascular endothelial growth factor (VEGF), placenta growth factor (PlGF) and their receptors (VEGFR) have important roles in vascular remo...

journal_title：Placenta

authors： Tseng JJ,Chou MM,Hsieh YT,Wen MC,Ho ES,Hsu SL

更新日期：2006-01-01 00:00:00

abstract：:Human placental villi are surfaced by an outer multinucleated syncytiotrophoblast and underlying mononucleated cytotrophoblasts. Conflicting data have attributed one, or the other, of these villous trophoblast phenotypes to undergo enhanced apoptosis in complicated pregnancies, compared to term, normotensive pregnanci...

journal_title：Placenta

authors： Longtine MS,Chen B,Odibo AO,Zhong Y,Nelson DM

更新日期：2012-05-01 00:00:00

abstract：:Telomeres are nucleoprotein structures located at the termini of chromosomes. They are essential for chromosome stability. Telomeres become shorter due to mitotic cycles and environmental factors. When telomeres are shortened and therefore dysfunctional, cellular senescence occurs and organ dysfunction might develop. ...

journal_title：Placenta

authors： Biron-Shental T,Sadeh-Mestechkin D,Amiel A

更新日期：2016-03-01 00:00:00

abstract：:This study examines the vasorelaxation of isolated human placental chorionic plate arteries and the perfused fetal-placental vasculature, in vitro, to a variety of nitrovasodilator compounds including glyceryl trinitrate (GTN) sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP), S-nitroso-N-glutathione ...

journal_title：Placenta

authors： Zhang XQ,Kwek K,Read MA,Donoghue JF,Walters WA

更新日期：2001-04-01 00:00:00

abstract：:The IPL/TSSC3 gene is expressed nearly exclusively from the maternal allele, and its protein product acts to limit placental growth in mice. This protein specifically marks Type II trophoblast in the labyrinthine layer of the mouse placenta. To investigate mouse-human homologies, we carried out immunohistochemistry wi...

journal_title：Placenta

authors： Saxena A,Frank D,Panichkul P,Van den Veyver IB,Tycko B,Thaker H

更新日期：2003-09-01 00:00:00

abstract：:The hormone leptin (OB) and its receptor (OB-R) are key homeostatic regulators of mammalian body weight. Two predominant isoforms of OB-R are expressed by alternative splicing: the long form, OB-RL, with full signalling capacity is highly expressed in the hypothalamus and the short, signalling-defective form, OB-Rs, i...

journal_title：Placenta

authors： Ebenbichler CF,Kaser S,Laimer M,Wolf HJ,Patsch JR,Illsley NP

更新日期：2002-07-01 00:00:00

abstract：:Accumulation of advanced oxidation protein products (AOPPs) is prevalent in obesity, advanced maternal age, diabetes mellitus, and polycystic ovary syndrome. Alterations in the regulation and signaling of angiogenic pathways have been recognized as a link between these conditions and pre-eclampsia. To investigate the ...

journal_title：Placenta

authors： Huang QT,Wang SS,Zhang M,Huang LP,Tian JW,Yu YH,Wang ZJ,Zhong M

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:The placenta is a transient organ the functioning of which has health consequences far beyond the embryo/fetus. Understanding the biology of any system (organ, organism, single cell, etc) requires a comprehensive and inclusive approach which embraces all the biomedical disciplines and 'omic' technologies a...

journal_title：Placenta

authors： Mayhew TM

更新日期：2015-04-01 00:00:00

abstract：:Sections of human term placentae delivered at low and high altitude to indigenous and non-indigenous populations in Bolivia were analysed by stereological methods. Estimates were obtained of the arithmetic and harmonic mean thicknesses of villous membrane and of trophoblast. These values were then used to derive indic...

journal_title：Placenta

authors： Jackson MR,Mayhew TM,Haas JD

更新日期：1988-01-01 00:00:00

abstract：:TRH immunological and biological activity was characterized in rat placental extracts. Placentae were extracted sequentially with 2 N acetic acid and glacial acetic acid. The lyophilized residues were further extracted with 90 per cent methanol, and the extracts were then dried, and reextracted with distilled water. W...

journal_title：Placenta

authors： Shambaugh GE 3rd,Kubek M,Wilber JF

更新日期：1983-10-01 00:00:00

abstract：INTRODUCTION:Feeding pregnant broodmares with cereal concentrates has been shown to increase maternal insulin resistance and affect foal metabolism in the short and long-term. These effects are likely to be mediated by the placenta. Here, we investigated feto-placental biometry and placental structure and function at t...

journal_title：Placenta

authors： Robles M,Peugnet P,Dubois C,Piumi F,Jouneau L,Bouchez O,Aubrière MC,Dahirel M,Aioun J,Wimel L,Couturier-Tarrade A,Chavatte-Palmer P

更新日期：2018-04-01 00:00:00

abstract：:Parathyroid hormone-related protein (PTHrP), the major factor responsible for hypercalcaemia of malignancy, is widely expressed in normal adult and fetal tissues. In this study, the distribution of PTHrP was examined in human term placenta and membranes by immunohistochemistry using antisera to PTHrP 1-34 and 37-67. P...

journal_title：Placenta

authors： Emly JF,Gregory J,Bowden SJ,Ahmed A,Whittle MJ,Rushton DI,Ratcliffe WA

更新日期：1994-09-01 00:00:00

abstract：:We investigated the localization of the three subtypes of (Fc gamma R) in the normal human placenta using immunohistochemical and immunocytochemical techniques with specific monoclonal antibodies. The analysis revealed that Fc gamma RI was expressed on Hofbauer cells, that Fc gamma RII was expressed on Hofbauer cells ...

journal_title：Placenta

authors： Kameda T,Koyama M,Matsuzaki N,Taniguchi T,Saji F,Tanizawa O

更新日期：1991-01-01 00:00:00

abstract：:In the present study, we characterized the expression of lymphocyte antigen 6, locus E (Ly6e) in mouse placental trophoblast. We identified Ly6e mRNA expression in trophoblast stem (TS) cells by a gene expression screen. In vivo, Ly6e was first detectable by mRNA in situ hybridization in the chorion beginning at E8.5 ...

journal_title：Placenta

authors： Hughes M,Natale BV,Simmons DG,Natale DR

更新日期：2013-09-01 00:00:00

abstract：INTRODUCTION:The ratio of birthweight to placental weight (BW:PW) is often used as a measure of placental efficiency in humans and animals. However, ratios have properties that are known to lead to spurious results. An alternative approach is the use of residuals from regression, which reflect whether birthweight is hi...

journal_title：Placenta

authors： Christians JK,Grynspan D,Greenwood SL,Dilworth MR

更新日期：2018-08-01 00:00:00

abstract：:The binding of oestradiol in human placental tissue obtained from spontaneous and caesarean deliveries was investigated. Villous tissue was homogenized and the 800 g 'cytosol' supernatant treated with ammonium sulphate. The precipitate was redissolved and the preparation then equilibrated with [3H]oestradiol. After se...

journal_title：Placenta

authors： Laminski NA,Hammond KD

更新日期：1985-09-01 00:00:00

abstract：INTRODUCTION:Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder unique to pregnancy that is associated with increased rates of fetal distress and demise. While acute hypoxia is believed to cause the pathophysiology of ICP, direct molecular evidence for this is lacking. Here, we analyzed expression of three...

journal_title：Placenta

authors： Wei W,Hu YY

更新日期：2014-09-01 00:00:00

abstract：:Stereological methods were used to test whether or not altitudinal, ethnic and sex differences in birthweight in Bolivia are associated with differences in placental morphology. Estimates of the volumes, surface areas, lengths and diameters of villi and of fetal capillaries were obtained by analysing paraffin sections...

journal_title：Placenta

authors： Jackson MR,Mayhew TM,Haas JD

更新日期：1987-09-01 00:00:00

abstract：:Placental endoplasmic reticulum (ER) stress has been postulated in the pathophysiology of pre-eclampsia (PE) and intrauterine growth restriction (IUGR), but its activation remains elusive. Oxidative stress induced by ischaemia/hypoxia-reoxygenation activates ER stress in vitro. Here, we explored whether exposure to la...

journal_title：Placenta

authors： Veerbeek JH,Tissot Van Patot MC,Burton GJ,Yung HW

更新日期：2015-01-01 00:00:00

abstract：:The placenta is composed of the amnion, chorionic plate, villous and smooth chorion, decidua basalis, and umbilical cord. The amnion is a readily obtainable source of a large number of cells and cell types, including epithelium, mesenchyme, and endothelium, and is thus an allogeneic resource for regenerative medicine....

journal_title：Placenta

authors： Umezawa A,Hasegawa A,Inoue M,Tanuma-Takahashi A,Kajiwara K,Makino H,Chikazawa E,Okamoto A

更新日期：2019-09-01 00:00:00

abstract：:Interleukin-6 (IL-6) and its receptor complex, IL-6 receptor (IL-6R) and gp130, are critical in induction of suppressor of cytokine signalling-3 (SOCS-3) protein, a negative cytokine regulator and anti-inflammatory mediator, in a biological system. Increased inflammatory response is believed to contribute to the place...

journal_title：Placenta

authors： Zhao S,Gu Y,Dong Q,Fan R,Wang Y

更新日期：2008-12-01 00:00:00

abstract：:Prior studies have shown that levels of corticotrophin-releasing hormone (CRH) in the umbilical cord blood of infants born after pregnancies complicated by pre-eclampsia are significantly higher than fetal plasma CRH concentrations in uncomplicated pregnancies. In the present study we have measured CRH by radioimmunoa...

journal_title：Placenta

authors： Goland RS,Conwell IM,Jozak S

更新日期：1995-06-01 00:00:00

abstract：:During placental development, human cytotrophoblast cells can differentiate to either villous syncytiotrophoblast cells or invasive extravillous trophoblast cells. We hypothesize that oxygen tension plays a critical role in determining the pathway of cytotrophoblast differentiation. A highly purified preparation of cy...

journal_title：Placenta

authors： Robins JC,Heizer A,Hardiman A,Hubert M,Handwerger S

更新日期：2007-11-01 00:00:00

abstract：INTRODUCTION:Escherichia coli is recognized as an etiological bacteria associated with chorioamnionitis and the preterm premature rupture of fetal membranes. This pathological condition induces pro-inflammatory cytokines and degradative metalloproteinases, which are considered biological markers secreted in an acute st...

journal_title：Placenta

authors： Osorio-Caballero M,Perdigón-Palacio C,García-López G,Flores-Herrera O,Olvera-Sánchez S,Morales-Méndez I,Sosa-González I,Acevedo JF,Guzmán-Grenfell AM,Molina-Hernández A,Díaz NF,Flores-Herrera H

更新日期：2015-03-01 00:00:00

abstract：:Endothelium derived relaxing factor (EDRF), now widely believed to be nitric oxide (NO), may play an important part in the control of fetoplacental vascular tone. To further explore this role we have determined the relaxation responses to exogenous NO and examined the temporal relationship between intracellular concen...

journal_title：Placenta

authors： Hull AD,White CR,Pearce WJ

更新日期：1994-06-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at the post-transcriptional level. While mostly intracellular, a portion of cellular miRNAs is released to the circulation and their level in the plasma is altered in certain pathological conditions such as cancer, and also during pregnancy. We...

journal_title：Placenta

authors： Mouillet JF,Chu T,Hubel CA,Nelson DM,Parks WT,Sadovsky Y

更新日期：2010-09-01 00:00:00

abstract：:Workshops are an important part of the IFPA annual meeting. At the IFPA meeting 2008 diverse topics were discussed in 12 themed workshops. Topics covered included: immunology of placentation; galectins and trophoblast invasion; signaling in implantation and invasion; markers to identify trophoblast subpopulations; pla...

journal_title：Placenta

authors： Lash GE,Ansari T,Bischof P,Burton GJ,Chamley L,Crocker I,Dantzer V,Desoye G,Drewlo S,Fazleabas A,Jansson T,Keating S,Kliman HJ,Lang I,Mayhew T,Meiri H,Miller RK,Nelson DM,Pfarrer C,Roberts C,Sammar M,Sharma S,

更新日期：2009-03-01 00:00:00

abstract：:Pregnant mothers are exposed to a wide variety of foreign chemicals. This exposure is most commonly due to maternal medication, lifestyle factors, such as smoking, drug abuse, and alcohol consumption, or occupational and environmental sources. Foreign compounds may interfere with placental functions at many levels e.g...

journal_title：Placenta

authors： Myllynen P,Pasanen M,Pelkonen O

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVES:In maternal diabetes the placenta is large with abnormal vascular development and increased villous volume. We used a novel stereological 3D power Doppler ultrasound technique to investigate differences in-vivo in the placental fractional volume of power Doppler signal (FrVol-PD) between women with and witho...

journal_title：Placenta

authors： Jones NW,Deshpande R,Mousa HA,Mansell P,Raine-Fenning N,Bugg G

更新日期：2013-11-01 00:00:00