Functional characterisation of brassinosteroid receptor MtBRI1 in Medicago truncatula.

abstract：:Human sociality depends upon the benefits of mutual aid and extensive communication. However, diverse norms and preferences complicate mutual aid, and ambiguity in meaning hinders communication. Here we demonstrate that these two problems can work together to enhance cooperation through the strategic use of deliberate...

journal_title：Scientific reports

authors： Smaldino PE,Flamson TJ,McElreath R

更新日期：2018-03-20 00:00:00

abstract：:De novo mutations (DNMs), including germinal and postzygotic mutations (PZMs), are a strong source of causality for Autism Spectrum Disorder (ASD). However, the biological processes involved behind them remain unexplored. Our aim was to detect DNMs (germinal and PZMs) in a Spanish ASD cohort (360 trios) and to explore...

journal_title：Scientific reports

authors： Alonso-Gonzalez A,Calaza M,Amigo J,González-Peñas J,Martínez-Regueiro R,Fernández-Prieto M,Parellada M,Arango C,Rodriguez-Fontenla C,Carracedo A

更新日期：2021-01-11 00:00:00

abstract：:There is an increasing risk of mental disorders, such as acute stress disorder (ASD), post-traumatic stress disorder (PTSD) and depression among survivors who were trapped in rubble during earthquake. Such long-term impaction of a single acute restraint stress has not been extensively explored. In this study, we subje...

journal_title：Scientific reports

authors： Chu X,Zhou Y,Hu Z,Lou J,Song W,Li J,Liang X,Chen C,Wang S,Yang B,Chen L,Zhang X,Song J,Dong Y,Chen S,He L,Xie Q,Chen X,Li W

更新日期：2016-09-09 00:00:00

abstract：:Temporal baselines are needed for biodiversity, in order for the change in biodiversity to be measured over time, the targets for biodiversity conservation to be defined and conservation progress to be evaluated. Limited biodiversity information is widely recognized as a major barrier for identifying temporal baseline...

journal_title：Scientific reports

authors： Mihoub JB,Henle K,Titeux N,Brotons L,Brummitt NA,Schmeller DS

更新日期：2017-01-30 00:00:00

abstract：:Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play roles in the nervous system. The analysis of roles in both standard and pathological conditions benefits from a model organism with rapid development and early onset of behaviors. Such a model was developed by ablating the zebrafish panx1a gene using T...

journal_title：Scientific reports

authors： Safarian N,Whyte-Fagundes P,Zoidl C,Grigull J,Zoidl G

更新日期：2020-06-12 00:00:00

abstract：:Although blood-based liquid biopsies have emerged as a promising non-invasive method to detect biomarkers in various cancers, limited progress has been made for brain tumors. One major obstacle is the blood-brain barrier (BBB), which hinders efficient passage of tumor biomarkers into the peripheral circulation. The ob...

journal_title：Scientific reports

authors： Zhu L,Cheng G,Ye D,Nazeri A,Yue Y,Liu W,Wang X,Dunn GP,Petti AA,Leuthardt EC,Chen H

更新日期：2018-04-26 00:00:00

abstract：:Hematopoietic stem cells (HSCs) maintain the entire blood system throughout life and are utilized in therapeutic approaches for blood diseases. Prospective isolation of highly purified HSCs is crucial to understand the molecular mechanisms underlying regulation of HSCs. The zebrafish is an elegant genetic model for th...

journal_title：Scientific reports

authors： Kobayashi I,Kondo M,Yamamori S,Kobayashi-Sun J,Taniguchi M,Kanemaru K,Katakura F,Traver D

更新日期：2019-10-02 00:00:00

abstract：:The focus of this study is to evaluate the efficacy of Machine Learning (ML) algorithms in the long-lead prediction of El Niño (La Niña) Modoki (ENSO Modoki) index (EMI). We evaluated two widely used non-linear ML algorithms namely Support Vector Regression (SVR) and Random Forest (RF) to forecast the EMI at various l...

journal_title：Scientific reports

authors： Pal M,Maity R,Ratnam JV,Nonaka M,Behera SK

更新日期：2020-01-15 00:00:00

abstract：:A considerable body of evidence links together mitochondrial dysfunctions, toxic action of metalloid oxyanions, and system and neurodegenerative disorders. In this study we have used the model yeast Saccharomyces cerevisiae to investigate the genetic determinants associated with tellurite resistance/sensitivity. Nitro...

journal_title：Scientific reports

authors： Pontieri P,Hartings H,Di Salvo M,Massardo DR,De Stefano M,Pizzolante G,Romano R,Troisi J,Del Giudice A,Alifano P,Del Giudice L

更新日期：2018-08-13 00:00:00

abstract：:The extensive redundancy in the use of invasion ligands by Plasmodium falciparum, and its unique ability to switch between invasion pathways have hampered vaccine development. P. falciparum strains Dd2 and W2mef have been shown to change from sialic acid (SA)-dependent to SA-independent phenotypes when selected on neu...

journal_title：Scientific reports

authors： Awandare GA,Nyarko PB,Aniweh Y,Ayivor-Djanie R,Stoute JA

更新日期：2018-04-10 00:00:00

abstract：:A new, extraordinary palaeontinid Hallakkungis amisanus Nam, Wang &Szwedo, gen. et sp. nov., from the Upper Triassic of the Amisan Formation in Boryeong City, Korea is described. It is the first Palaeontinidae from Korea. The newly described taxon displays a mosaic of characters present in presumed ancestors of this i...

journal_title：Scientific reports

authors： Nam KS,Wang Y,Ren D,Kim JH,Szwedo J

更新日期：2017-01-18 00:00:00

abstract：:Atherosclerotic arteries exhibit characteristic constrictions and substantial deviations from cylindrical shape. Therefore, determining the artery's cross-section along the centerline is challenging, although high-resolution isotropic three-dimensional data are available. Herein, we apply high-resolution computed tomo...

journal_title：Scientific reports

authors： Buscema M,Hieber SE,Schulz G,Deyhle H,Hipp A,Beckmann F,Lobrinus JA,Saxer T,Müller B

更新日期：2019-10-04 00:00:00

abstract：:(R-)miniCHOP therapy, which delivers approximately half-doses of the (R-)CHOP regimen, has shown efficacy and safety in patients who are more than 80 years old. This study aimed to compare the area under the plasma concentration-time curves (AUCs) of vincristine (VCR), doxorubicin (DXR), and cyclophosphamide (CPA) bet...

journal_title：Scientific reports

authors： Nakagawa J,Takahata T,Hyodo R,Chen Y,Hasui K,Sasaki K,Saito K,Ueno K,Hosoi K,Terui K,Sato A,Niioka T

更新日期：2021-01-12 00:00:00

abstract：:Coherent Anti-Stokes Raman Spectroscopy (CARS) is performed on single spores (conidia) of the fungus Aspergillus nidulans in order to establish a baseline measurement for fungal spores. Chemical maps of single spores are generated and spectral differentiation between the cell wall and the cytoplasm is achieved. Princi...

journal_title：Scientific reports

authors： D Strycker B,Han Z,Commer B,D Shaw B,V Sokolov A,O Scully M

更新日期：2019-02-11 00:00:00

abstract：:Understanding the transmission patterns of African swine fever (ASF) among wild boar (Sus scrofa) is an issue of major interest, especially in the wake of the current ASF epidemic. Given the high stability of ASF-virus, there is concern about scavengers spreading infectious carcass material in the environment. Here, w...

journal_title：Scientific reports

authors： Probst C,Gethmann J,Amler S,Globig A,Knoll B,Conraths FJ

更新日期：2019-08-07 00:00:00

abstract：:In many ways, the complement of cell subtypes determines the information processing that a local brain circuit can perform. For example, the balance of excitatory and inhibitory (E/I) signaling within a brain region contributes to response magnitude and specificity in ways that influence the effectiveness of informati...

journal_title：Scientific reports

authors： Gogola JV,Gores EO,London SE

更新日期：2019-12-27 00:00:00

abstract：:Cholestasis impairs liver regeneration following partial liver resection (PHx). Bile acid receptor farnesoid X-receptor (FXR) is a key mediator of liver regeneration. The effects of FXR agonist obeticholic acid (OCA) on liver (re)growth were therefore studied in cholestatic rats. Animals underwent sham surgery or reve...

journal_title：Scientific reports

authors： van Golen RF,Olthof PB,Lionarons DA,Reiniers MJ,Alles LK,Uz Z,de Haan L,Ergin B,de Waart DR,Maas A,Verheij J,Jansen PL,Damink SWO,Schaap FG,van Gulik TM,Heger M

更新日期：2018-11-08 00:00:00

abstract：:Soil degradation due to erosion is a significant worldwide problem at different spatial (from pedon to watershed) and temporal scales. All stages and factors in the erosion process must be detected and evaluated to reduce this environmental issue and protect existing fertile soils and natural ecosystems. Laboratory st...

journal_title：Scientific reports

authors： Shojaei S,Kalantari Z,Rodrigo-Comino J

更新日期：2020-11-19 00:00:00

abstract：:Due to their convergent evolution, dogs have been suggested as a good model for the evolution of human social skills, such as tolerance and cooperativeness. However, recent studies have revealed that wolves (dogs' closest undomesticated relatives) are more tolerant and cooperative with conspecifics than dogs. It is st...

journal_title：Scientific reports

authors： Range F,Marshall-Pescini S,Kratz C,Virányi Z

更新日期：2019-03-07 00:00:00

abstract：:Predicting the risk of liver metastasis can have important prognostic and therapeutic implications, given the availability of liver-directed therapy. Uveal melanoma has a striking predisposition for liver metastasis despite the absence of anatomical proximity. Understanding its biology may uncover factors promoting li...

journal_title：Scientific reports

authors： Tsantoulis P,Delorenzi M,Bièche I,Vacher S,Mariani P,Cassoux N,Houy A,Stern MH,Roman-Roman S,Dietrich PY,Roth A,Cacheux W

更新日期：2019-11-20 00:00:00

abstract：:When complementary resources are required for an optimal life cycle, most animals need to move between different habitats. However, the level of connectivity between resources can vary and, hence, influence individuals' behaviour. We show that landscape composition and configuration affect the connectivity between bre...

journal_title：Scientific reports

authors： Evens R,Beenaerts N,Neyens T,Witters N,Smeets K,Artois T

更新日期：2018-02-14 00:00:00

abstract：:Attention and saccadic eye movements are critical components of visual perception. Recent studies proposed the hypothesis of a tight coupling between saccadic adaptation (SA) and attention: SA increases the processing speed of unpredictable stimuli, while increased attentional load boosts SA. Moreover, their cortical ...

journal_title：Scientific reports

authors： Nicolas J,Bidet-Caulet A,Pélisson D

更新日期：2020-08-10 00:00:00

abstract：:Rheumatoid Arthritis (RA) causes chronic inflammation of joints. The cytokines TNFα and IFNγ are central players in RA, however their source has not been fully elucidated. Natural Killer (NK) cells are best known for their role in elimination of viral-infected and transformed cells, and they secrete pro-inflammatory c...

journal_title：Scientific reports

authors： Yamin R,Berhani O,Peleg H,Aamar S,Stein N,Gamliel M,Hindi I,Scheiman-Elazary A,Gur C

更新日期：2019-02-04 00:00:00

abstract：:Although biophysical yield responses to local warming have been studied, we know little about how crop yield growth-a function of climate and technology-responds to global temperature and socioeconomic changes. Here, we present the yield growth of major crops under warming conditions from preindustrial levels as simul...

journal_title：Scientific reports

authors： Iizumi T,Furuya J,Shen Z,Kim W,Okada M,Fujimori S,Hasegawa T,Nishimori M

更新日期：2017-08-10 00:00:00

abstract：:Oxidative stress (OS), mitochondrial dysfunction, and dysregulation of alpha-synuclein (aSyn) homeostasis are key pathogenic factors in Parkinson's disease. Nevertheless, the role of aSyn in mitochondrial physiology remains elusive. Thus, we addressed the impact of aSyn specifically on mitochondrial response to OS in ...

journal_title：Scientific reports

authors： Menges S,Minakaki G,Schaefer PM,Meixner H,Prots I,Schlötzer-Schrehardt U,Friedland K,Winner B,Outeiro TF,Winklhofer KF,von Arnim CA,Xiang W,Winkler J,Klucken J

更新日期：2017-02-22 00:00:00

abstract：:Controlling the nanoscale arrangement in polymer-fullerene organic solar cells is of paramount importance to boost the performance of such promising class of photovoltaic diodes. In this work, we use a pseudo-bilayer system made of poly(2,5-bis(3-hexadecylthiophen-2-yl)thieno[3,2-b]thiophene (PBTTT) and [6,6]-phenyl-C...

journal_title：Scientific reports

authors： Paternò GM,Skoda MW,Dalgliesh R,Cacialli F,Sakai VG

更新日期：2016-10-04 00:00:00

abstract：:Microalgae have great potential for the production of biofuels due to the ability of the organism to accumulate large quantities of storage lipids under stress conditions. Mitogen activated protein kinase (MAPK) signaling cascades are widely recognized for their role in stress response signal transduction in eukaryote...

journal_title：Scientific reports

authors： Yang A,Suh WI,Kang NK,Lee B,Chang YK

更新日期：2018-09-14 00:00:00

abstract：:Botulinum neurotoxins (BoNTs) are highly potent toxins that cleave neuronal SNARE proteins required for neurotransmission, causing flaccid paralysis and death by asphyxiation. Currently, there are no clinical treatments to delay or reverse BoNT-induced blockade of neuromuscular transmission. While aminopyridines have ...

journal_title：Scientific reports

authors： Beske PH,Hoffman KM,Machamer JB,Eisen MR,McNutt PM

更新日期：2017-11-20 00:00:00

abstract：:Memristive systems have gained considerable attention in the field of neuromorphic engineering, because they allow the emulation of synaptic functionality in solid state nano-physical systems. In this study, we show that memristive behavior provides a broad working framework for the phenomenological modelling of cellu...

journal_title：Scientific reports

authors： Diederich N,Bartsch T,Kohlstedt H,Ziegler M

更新日期：2018-06-19 00:00:00

abstract：:Protein aggregation is a common biological phenomenon, observed in different physiological and pathological conditions. Decreased protein solubility and a tendency to aggregate is also observed during physiological aging but the causes are currently unknown. Herein we performed a biophysical separation of aging-relate...

journal_title：Scientific reports

authors： Tanase M,Urbanska AM,Zolla V,Clement CC,Huang L,Morozova K,Follo C,Goldberg M,Roda B,Reschiglian P,Santambrogio L

更新日期：2016-01-18 00:00:00