Evidence for the importance of post-transcriptional regulatory changes in ovarian cancer progression and the contribution of miRNAs.

abstract：:We present a combined geomorphological and biochronological study aimed at providing age constraints to the deposits forming a wide paleo-surface in the coastal area of the Tyrrhenian Sea, south of Anzio promontory (central Italy). We review the faunal assemblage recovered in Campoverde, evidencing the occurrence of t...

journal_title：Scientific reports

authors： Marra F,Petronio C,Ceruleo P,Di Stefano G,Florindo F,Gatta M,La Rosa M,Rolfo MF,Salari L

更新日期：2018-12-13 00:00:00

abstract：:Obesity affects male fertility and maternal diabetes affects the offspring sperm epigenome. However, the effects of in utero exposure to maternal glucose intolerance in combination with postnatal high fat, high sucrose (HFHS) diet consumption on offspring spermatogenesis is not clear. The present study was designed to...

journal_title：Scientific reports

authors： Mao J,Pennington KA,Talton OO,Schulz LC,Sutovsky M,Lin Y,Sutovsky P

更新日期：2018-05-16 00:00:00

abstract：:Glioblastoma multiforme has a poor prognosis and is highly chemoresistant. In this study, we implanted biodegradable 1,3-bis[2-chloroethyl]-1-nitroso-urea-, irinotecan-, and cisplatin-eluting poly[(d,l)-lactide-co-glycolide] (BIC/PLGA) and virgin nanofibrous membranes on the brain surface of C6 glioma-bearing rats in ...

journal_title：Scientific reports

authors： Tseng YY,Huang YC,Yang TC,Yang ST,Liu SC,Chang TM,Kau YC,Liu SJ

更新日期：2016-07-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Herrera-Nieto P,Pérez A,De Fabritiis G

更新日期：2020-09-29 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a regulatory and cytoprotective neuropeptide, its deficiency implies accelerated aging in mice. It is present in the auditory system having antiapoptotic effects. Expression of Ca2+-binding proteins and its PAC1 receptor differs in the inner ear of PACAP-de...

journal_title：Scientific reports

authors： Fulop DB,Humli V,Szepesy J,Ott V,Reglodi D,Gaszner B,Nemeth A,Szirmai A,Tamas L,Hashimoto H,Zelles T,Tamas A

更新日期：2019-10-10 00:00:00

abstract：:The controlled preparation of Au nanoparticles (NPs) in the size range of 6 to 22 nm is explored in this study. The Au NPs were prepared by the reduction of tetrachloroauric acid using maltose in the presence of nonionic surfactant Tween 80 at various concentrations to control the size of the resulting Au NPs. With in...

journal_title：Scientific reports

authors： Suchomel P,Kvitek L,Prucek R,Panacek A,Halder A,Vajda S,Zboril R

更新日期：2018-03-15 00:00:00

abstract：:The CRISPR system holds much promise for successful genome engineering, but therapeutic, industrial, and research applications will place high demand on improving the specificity and efficiency of this tool. CT-Finder (http://bioinfolab.miamioh.edu/ct-finder) is a web service to help users design guide RNAs (gRNAs) op...

journal_title：Scientific reports

authors： Zhu H,Misel L,Graham M,Robinson ML,Liang C

更新日期：2016-05-23 00:00:00

abstract：:Much uncertainty exists about the history of the Greenland Ice Sheet (GIS), particularly as to the frequency of extreme shelf edge glaciations. Because the last glaciation removed most of the record of earlier GIS extent on land and shelf exploration of the older GIS glacial record requires the use of deeper marine ar...

journal_title：Scientific reports

authors： Nielsen T,Kuijpers A

更新日期：2013-01-01 00:00:00

abstract：:Previous genetic studies have revealed that a pollen-specific calmodulin-binding protein, No Pollen Germination 1 (NPG1), is required for pollen germination. However, its mode of action is unknown. Here we report direct interaction of NPG1 with pectate lyase-like proteins (PLLs). A truncated form of AtNPG1 lacking the...

journal_title：Scientific reports

authors： Shin SB,Golovkin M,Reddy AS

更新日期：2014-06-12 00:00:00

abstract：:CD4+latency-associated peptide (LAP)+ T cells are a newly discovered T cell subset with suppressive function on immune responses. In this study, we investigate the role of CD4+LAP+ T cells on mice corneal allograft survival by down-regulating their expression using anti-LAP mAb. We show that a blockage of LAP leads to...

journal_title：Scientific reports

authors： Li S,Lu H,Sella R,Zhang W,Dong H,Guo C,Afshari NA,Pan Z,Jie Y

更新日期：2018-05-22 00:00:00

abstract：:Long-term monitoring of host-parasite interactions is important for understanding the consequences of infection on host fitness and population dynamics. In an eight-year survey of the loggerhead sea turtle (Caretta caretta) population nesting in Cabo Verde, we determined the spatiotemporal variation of Ozobranchus mar...

journal_title：Scientific reports

authors： Lockley EC,Fouda L,Correia SM,Taxonera A,Nash LN,Fairweather K,Reischig T,Durão J,Dinis H,Roque SM,Lomba JP,Dos Passos L,Cameron SJK,Stiebens VA,Eizaguirre C

更新日期：2020-10-29 00:00:00

abstract：:Novel pain killers without adverse effects are urgently needed. Opioids induce central and intestinal side effects such as respiratory depression, sedation, addiction, and constipation. We have recently shown that a newly designed agonist with a reduced acid dissociation constant (pKa) abolished pain by selectively ac...

journal_title：Scientific reports

authors： Spahn V,Del Vecchio G,Rodriguez-Gaztelumendi A,Temp J,Labuz D,Kloner M,Reidelbach M,Machelska H,Weber M,Stein C

更新日期：2018-06-12 00:00:00

abstract：:RNA interference (RNAi) is being developed for the management of pests that destroy crops. The twospotted Spider Mite (TSSM), Tetranychus urticae is a worldwide pest due to its unique physiological and behavioral characteristics including extraordinary ability to detoxify a wide range of pesticides and feed on many ho...

journal_title：Scientific reports

authors： Yoon JS,Sahoo DK,Maiti IB,Palli SR

更新日期：2018-10-02 00:00:00

abstract：:Solid-state femtosecond lasers have stimulated the broad adoption of multiphoton microscopy in the modern laboratory. However, these devices remain costly. Fiber lasers offer promise as a means to inexpensively produce ultrashort pulses of light suitable for nonlinear microscopy in compact, robust and portable devices...

journal_title：Scientific reports

authors： Davoudzadeh N,Ducourthial G,Spring BQ

更新日期：2019-03-12 00:00:00

abstract：:Hyperdisulfide-constrained peptides are distinguished by their high stability and diverse functions. Thus far, these peptides have been reported from animals only but their occurrence in plants are rare. Here, we report the discovery, synthesis and characterization of a hyperdisulfide-constrained peptides family of ap...

journal_title：Scientific reports

authors： Wong KH,Tan WL,Xiao T,Tam JP

更新日期：2017-07-21 00:00:00

abstract：:Mueller microscopes enable imaging of the optical anisotropic properties of biological or non-biological samples, in phase and amplitude, at sub-micrometre scale. However, the development of Mueller microscopes poses an instrumental challenge: the production of polarimetric parameters must be sufficiently quick to ens...

journal_title：Scientific reports

authors： Rivet S,Dubreuil M,Bradu A,Le Grand Y

更新日期：2019-03-08 00:00:00

abstract：:Loss of regenerative capacity plays a critical role in age-related autoimmune hepatitis. Evidence implicates SIRT1 and p66shc in cell senescence, apoptosis, oxidative stress, and proliferation. This study investigated the effect of resveratrol on concanavalin A (Con A)-induced hepatitis in aged mice and the roles of S...

journal_title：Scientific reports

authors： Huang TH,Chen CC,Liu HM,Lee TY,Shieh SH

更新日期：2017-06-02 00:00:00

abstract：:Cattleyak are interspecific hybrids between cattle and yak, exhibiting the same prominent adaptability as yak and much higher performances than yak. However, male infertility of cattleyak resulted from spermatogenic arrest has greatly restricted their effective utilization in yak breeding. In past decades, much work h...

journal_title：Scientific reports

authors： Xu C,Wu S,Zhao W,Mipam T,Liu J,Liu W,Yi C,Shah MA,Yu S,Cai X

更新日期：2018-01-12 00:00:00

abstract：:Mast Cells (MCs) are one of the first immune cells encountered by invading pathogens. Their presence in large numbers in the superficial dermis, where Leishmania is encountered, suggests that they may play a critical role in immune responses to Leishmania. In this study the interactions of Leishmania donovani, the cau...

journal_title：Scientific reports

authors： Naqvi N,Ahuja K,Selvapandiyan A,Dey R,Nakhasi H,Puri N

更新日期：2017-10-16 00:00:00

abstract：:We study the tight-binding model for a graphene tube with perimeter N threaded by a magnetic field. We show exactly that this model has different nontrivial topological phases as the flux changes. The winding number, as an indicator of topological quantum phase transition (QPT) fixes at N/3 if N/3 equals to its intege...

journal_title：Scientific reports

authors： Lin S,Zhang G,Li C,Song Z

更新日期：2016-08-24 00:00:00

abstract：:Although biophysical yield responses to local warming have been studied, we know little about how crop yield growth-a function of climate and technology-responds to global temperature and socioeconomic changes. Here, we present the yield growth of major crops under warming conditions from preindustrial levels as simul...

journal_title：Scientific reports

authors： Iizumi T,Furuya J,Shen Z,Kim W,Okada M,Fujimori S,Hasegawa T,Nishimori M

更新日期：2017-08-10 00:00:00

abstract：:Glucagon is a pancreatic hormone and increases the blood glucose levels. It may be incorporated in a dual hormone artificial pancreas, a device to automatically and continuously control blood glucose levels of individuals with diabetes. Artificial pancreas systems have been developed for use in the subcutaneous tissue...

journal_title：Scientific reports

authors： Åm MK,Dirnena-Fusini I,Fougner AL,Carlsen SM,Christiansen SC

更新日期：2020-08-13 00:00:00

abstract：:In this paper we report a low complexity compression method that is suitable for compact optical scanning holography (OSH) systems with different optical settings. Our proposed method can be divided into 2 major parts. First, an automatic decision maker is applied to select the rows of holographic pixels to be scanned...

journal_title：Scientific reports

authors： Tsang PW,Poon TC,Liu JP,Kim T,Kim YS

更新日期：2016-10-06 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality globally. Because most patients are diagnosed at advanced stages of the disease, multi-targeted tyrosine kinase inhibitor sorafenib is the only available drug to show limited effectiveness. Novel and effective therapies are unmet me...

journal_title：Scientific reports

authors： Wang J,Sun P,Chen Y,Yao H,Wang S

更新日期：2018-07-19 00:00:00

abstract：:Electrical stimulation is a common adjunct used to promote bone healing; its efficacy, however, remains uncertain. We conducted a meta-analysis of randomized sham-controlled trials to establish the efficacy of electrical stimulation for bone healing. We identified all trials randomizing patients to electrical or sham ...

journal_title：Scientific reports

authors： Aleem IS,Aleem I,Evaniew N,Busse JW,Yaszemski M,Agarwal A,Einhorn T,Bhandari M

更新日期：2016-08-19 00:00:00

abstract：:Frequency domain measures of heart rate variability (HRV) are associated with adverse events after a myocardial infarction. However, patterns in the traditional frequency domain (measured in Hz, or cycles per second) may capture different cardiac phenomena at different heart rates. An alternative is to consider freque...

journal_title：Scientific reports

authors： Liu Y,Scirica BM,Stultz CM,Guttag JV

更新日期：2016-10-06 00:00:00

abstract：:Two dimensional (2D) materials with a monolayer of atoms represent an ultimate control of material dimension in the vertical direction. Molybdenum sulfide (MoS2) monolayers, with a direct bandgap of 1.8 eV, offer an unprecedented prospect of miniaturizing semiconductor science and technology down to a truly atomic sca...

journal_title：Scientific reports

authors： Yu Y,Li C,Liu Y,Su L,Zhang Y,Cao L

更新日期：2013-01-01 00:00:00

abstract：:A series of β-NaLuF4 crystals were synthesized via a hydrothermal method. Hexagonal phase microdisks, microprisms, and microtubes were achieved by simply changing the amount of citric acid in the initial reaction solution. Pure red upconversion (UC) luminescence can be observed in β-NaLuF4:Yb(3+), Tm(3+), Er(3+) and L...

journal_title：Scientific reports

authors： Lin H,Xu D,Li A,Teng D,Yang S,Zhang Y

更新日期：2016-06-16 00:00:00

abstract：:The quality of avian semen is an important economic trait in poultry production. The present study examines the in vitro effects of non-thermal dielectric barrier discharge plasma on chicken sperm to determine the plasma conditions that can produce the optimum sperm quality. Exposure to 11.7 kV of plasma for 20 s is f...

journal_title：Scientific reports

authors： Zhang JJ,Do HL,Chandimali N,Lee SB,Mok YS,Kim N,Kim SB,Kwon T,Jeong DK

更新日期：2018-05-15 00:00:00

abstract：:Neutrophils are the first immune cells to kill invading microbes at sites of infection using a variety of processes, including the release of proteases, phagocytosis and the production of neutrophil extracellular traps (NETs). NET formation, or NETosis, is a specific and highly efficient process, which is induced by a...

journal_title：Scientific reports

authors： Sofoluwe A,Bacchetta M,Badaoui M,Kwak BR,Chanson M

更新日期：2019-11-12 00:00:00