Abstract:
:We developed a mouse line targeting midbrain dopamine neurons for Translating Ribosome Affinity Purification(TRAP). Here, we briefly report on the basic characterization of this mouse line including confirmation of expression of the transgene in midbrain dopamine neurons and validation of its effectiveness in capturing mRNA from these cells. We also report a translational profile of these neurons which may be of use to investigators studying the gene expression of these cells. Finally, we have provided the line to Jackson Laboratories for distribution and use in future studies.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Dougherty JDdoi
10.1038/s41598-017-08618-2subject
Has Abstractpub_date
2017-08-14 00:00:00pages
8117issue
1issn
2045-2322pii
10.1038/s41598-017-08618-2journal_volume
7pub_type
杂志文章abstract::Western North Pacific tropical cyclone (TC) activity is known to have a significant response to El Niño and Southern Oscillation (ENSO). Among the TC intensity classifications, "super typhoon", is widely used as a symbolic word for warning people about the potential for experiencing the most severe typhoon. This study...
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14681-6
更新日期:2017-10-27 00:00:00
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journal_title:Scientific reports
pub_type: 杂志文章
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journal_title:Scientific reports
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,已发布勘误
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更新日期:2017-05-26 00:00:00
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