Abstract:
PURPOSE:The aim of this study was to determine the effects of high-intensity aerobic interval training (AIT) on exercise hemodynamics in metabolic syndrome (MetS) volunteers. METHODS:Thirty-eight, MetS participants were randomly assigned to a training (TRAIN) or to a non-training control (CONT) group. TRAIN consisted of stationary interval cycling alternating bouts at 70-90% of maximal heart rate during 45 min day-1 for 6 months. RESULTS:CONT maintained baseline physical activity and no changes in cardiovascular function or MetS factors were detected. In contrast, TRAIN increased cardiorespiratory fitness (14% in VO2PEAK; 95% CI 9-18%) and improved metabolic syndrome (-42% in Z score; 95% CI 83-1%). After TRAIN, the workload that elicited a VO2 of 1500 ml min-1 increased 15% (95% CI 5-25%; P < 0.001). After TRAIN when subjects pedaled at an identical submaximal rate of oxygen consumption, cardiac output increased by 8% (95% CI 4-11%; P < 0.01) and stroke volume by 10% (95% CI, 6-14%; P < 0.005) being above the CONT group values at that time point. TRAIN reduced submaximal exercise heart rate (109 ± 15-106 ± 13 beats min-1; P < 0.05), diastolic blood pressure (83 ± 8-75 ± 8 mmHg; P < 0.001) and systemic vascular resistances (P < 0.01) below CONT values. Double product was reduced only after TRAIN (18.2 ± 3.2-17.4 ± 2.4 bt min-1 mmHg 10-3; P < 0.05). CONCLUSIONS:The data suggest that intense aerobic interval training improves hemodynamics during submaximal exercise in MetS patients. Specifically, it reduces diastolic blood pressure, systemic vascular resistances, and the double product. The reduction in double product, suggests decreased myocardial oxygen demands which could prevent the occurrence of adverse cardiovascular events during exercise in this population. CLINICALTRIALS. GOV IDENTIFIER:NCT03019796.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Mora-Rodriguez R,Fernandez-Elias VE,Morales-Palomo F,Pallares JG,Ramirez-Jimenez M,Ortega JFdoi
10.1007/s00421-017-3697-7subject
Has Abstractpub_date
2017-10-01 00:00:00pages
2065-2073issue
10eissn
1439-6319issn
1439-6327pii
10.1007/s00421-017-3697-7journal_volume
117pub_type
杂志文章,随机对照试验abstract:PURPOSE:In cross-country sit-skiing (XCSS), athletes with reduced trunk control predominantly sit with the knees higher than the hips (KH); a position often associated with large spinal flexion. Therefore, to improve spinal curvature a new sledge with frontal trunk support, where knees are lower than hips (KL) was crea...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-017-3596-y
更新日期:2017-06-01 00:00:00
abstract::Hypothermia is commonly found in accidents on land and at sea, yet its pulmonary circulatory effects have not been studied before. To study the effects of hypothermia on the right heart function and pulmonary circulation, cardiac catheterization was carried out on nine anaesthetized beagle dogs. The dogs were cooled b...
journal_title:European journal of applied physiology
pub_type: 杂志文章
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abstract:PURPOSE:The purpose of this study was to investigate the changes in blood lactate concentration (BL) and muscle activity patterns during a 15-m speed climbing competition that consisted of ten consecutive climbing actions on a standardized artificial wall in trained rock climbers. METHODS:Twelve trained rock climbers ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
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abstract:PURPOSE:Brain hemodynamics is fundamental for the functioning of the human being. Many biophysical factors affect brain circulation, so that a satisfactory understanding of its behavior is challenging. We developed a mathematical model to simulate cerebral and extracerebral flows and pressures in humans. METHODS:The m...
journal_title:European journal of applied physiology
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abstract::This review provides evidence for the hypothesis that electrostimulation strength training (EST) increases the force of a maximal voluntary contraction (MVC) through neural adaptations in healthy skeletal muscle. Although electrical stimulation and voluntary effort activate muscle differently, there is substantial evi...
journal_title:European journal of applied physiology
pub_type: 杂志文章,评审
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journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::Prolonged, strenuous exercise may lead to suppressive effects on the immune system, which might be responsible for a greater susceptibility to opportunistic infections. The aim of this study was to examine the influence of carbohydrate substitution (CHS) during prolonged, strenuous exercise on neutrophil granulocytes ...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
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abstract::Mathematical models of the acid-base chemistry of blood based upon mass action and mass balance equations have become popular as diagnostic tools in intensive care. The reference models using this approach are those based on the strong ion approach, but these models do not currently take into account the effects of ox...
journal_title:European journal of applied physiology
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-007-0558-9
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journal_title:European journal of applied physiology
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abstract::Whole-body vibration (WBV) leads to a rapid increase in intra-muscular temperature and enhances muscle power. The power-enhancing effects by WBV can, at least in part, be explained by intra-muscular temperature. However, this does not exclude possible neural effects of WBV occurring at the spinal level. The aim of thi...
journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-009-1215-2
更新日期:2010-01-01 00:00:00
abstract::An inverse relationship has been shown between running and cycling exercise economy and maximum oxygen uptake (VO2max). The purposes were: 1) determine the relationship between walking economy and VO2max; and 2) determine the relationship between muscle metabolic economy and muscle oxidative capacity and fiber type. S...
journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00421-005-1370-z
更新日期:2005-08-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2007-11-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-015-3235-4
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journal_title:European journal of applied physiology
pub_type: 杂志文章
doi:10.1007/s00421-008-0855-y
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journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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journal_title:European journal of applied physiology
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 杂志文章
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journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
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abstract:PURPOSE:Through time- and frequency-domain analysis, we compared the effects of acute hypobaric hypoxia on the changes in heart rate variability (HRV) following night sleeping and morning awakening in individuals with and without acute mountain sickness (AMS). METHOD:Thirty-nine nonacclimatised healthy individuals wer...
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pub_type: 杂志文章
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abstract::It is a common practice in Northern countries that children aged about 2 weeks to 2 years take their daytime sleep outdoors in prams in winter. The aim was to evaluate the thermal insulation of clothing of infants sleeping outdoors in winter. Clothing data of infants aged 3.5 months was collected, and sleep duration, ...
journal_title:European journal of applied physiology
pub_type: 杂志文章
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journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
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更新日期:2003-09-01 00:00:00
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journal_title:European journal of applied physiology
pub_type: 临床试验,杂志文章
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更新日期:2003-02-01 00:00:00