Strategies for Biofilm Inhibition and Virulence Attenuation of Foodborne Pathogen-Escherichia coli O157:H7.

Abstract:

:Enterohemorrhagic Escherichia coli (E. coli) O157:H7, a gram-negative bacteria identified as a foodborne pathogen causing severe disease is of great concern worldwide. The pathogenicity of E. coli O157:H7 is due to the presence of some virulence factors and its ability to form biofilm which resist antimicrobial compounds, withstand harsh environmental condition and protects from the host immune responses. Formation of biofilm is a multistep process such as adhesion, cellular aggregation and productions of extracellular matrix in which colonies are embedded. There are high numbers of research in the discovery of natural and synthetic compounds which can attenuate the E. coli O157:H7 biofilm formation as well as suppress virulence-related genes. The present review article focuses on the steps involved in E. coli O157:H7 biofilm formation, factors associated with virulence and attenuation.

journal_name

Curr Microbiol

journal_title

Current microbiology

authors

Oloketuyi SF,Khan F

doi

10.1007/s00284-017-1314-y

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

1477-1489

issue

12

eissn

0343-8651

issn

1432-0991

pii

10.1007/s00284-017-1314-y

journal_volume

74

pub_type

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