Abstract:
:Voltage gating is essential to the computational ability of neurons. We show this effect can be mimicked in a solid-state nanopore by functionalizing the pore interior with a redox active molecule. We study the integration of an active biological molecule-a quinone-into a solid state nanopore, and its subsequent induced voltage gating. We show that the voltage gating effect mimics biological gating systems in its classic sigmoidal voltage response, unlike previous synthetic voltage gating systems. Initially, the quinone undergoes a reduction due to radicals in the bulk solution, and is converted to the hydroquinone state. Upon deprontonation the hydroquinone then acts as a charged nanomechanical arm, which opens the channel under the applied potential. We establish that the quinone gains a single net charge when the pH inside of the nanopore reaches its pKa value, and explore factors that influence the net pH in the middle of the pore. Using a combination of theory, experiment and simulation, we conclude that concentration polarization and a shift of the pH inside of the channel is the main cause of this gating effect.
journal_name
Bioinspir Biomimjournal_title
Bioinspiration & biomimeticsauthors
Pevarnik M,Cui W,Yemenicioglu S,Rofeh J,Theogarajan Ldoi
10.1088/1748-3190/aa811bsubject
Has Abstractpub_date
2017-11-06 00:00:00pages
066008issue
6eissn
1748-3182issn
1748-3190journal_volume
12pub_type
杂志文章abstract::The formation aspects of a polycrystalline self-assembled bioceramic leading to the nucleation of hard-tissue mineral from a supersaturated solution are discussed. Scanning electron imaging and surface-sensitive interrogations of the nucleated mineral indicated the presence of an intermediate amorphous layer encompass...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/1/1/002
更新日期:2006-03-01 00:00:00
abstract::Recent developments in the design and propulsion of biomimetic autonomous underwater vehicles (AUVs) have focused on boxfish as models (e.g. Deng and Avadhanula 2005 Biomimetic micro underwater vehicle with oscillating fin propulsion: system design and force measurement Proc. 2005 IEEE Int. Conf. Robot. Auto. (Barcelo...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/3/3/034002
更新日期:2008-09-01 00:00:00
abstract::Passive dynamic walking is a model that walks down a shallow slope without any control or input. This model has been widely used to investigate how humans walk with low energy consumption and provides design principles for energy-efficient biped robots. However, the basin of attraction is very small and thin and has a...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/ab9283
更新日期:2020-07-15 00:00:00
abstract::Small birds and mammals commonly minimize respiratory heat loss with reciprocating counterflow exchangers in their nasal passageways. These animals extract heat from the air in an exhalation to warm those passageways and then use that heat to warm the subsequent inhalation. Although the near-constant volume of buildin...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/4/4/046004
更新日期:2009-12-01 00:00:00
abstract::This work is prompted by the quest for nanocomposites in which ordered, layered reinforcement preforms similar in structure to the arrangements seen in nacre are achieved without complex automated layer-by-layer assembly. Lamellar structures were obtained in montmorillonite films simply by slow drying without the use ...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/7/4/046004
更新日期:2012-12-01 00:00:00
abstract::Randomness is common in biological and artificial systems, resulting either from stochasticity of the environment or noise in organisms or devices themselves. In locomotor control, randomness is typically considered a nuisance. For example, during dynamic walking, randomness in stochastic terrain leads to metastable d...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/abac47
更新日期:2020-08-04 00:00:00
abstract::It is quite difficult for android robots to replicate the numerous and various types of human facial expressions owing to limitations in terms of space, mechanisms, and materials. This situation could be improved with greater knowledge regarding these expressions and their deformation rules, i.e. by using the biomimet...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aa8f33
更新日期:2017-11-27 00:00:00
abstract::Flight initiation is fundamental for survival, escape from predators and lifting payload from one place to another in biological fliers and can be broadly classified into jumping and non-jumping takeoffs. During jumping takeoffs, the legs generate most of the initial impulse. Whereas the wings generate most of the for...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aa7f52
更新日期:2017-09-26 00:00:00
abstract::Bats possess unique flight capabilities enabled by their wing morphology. While the articulated bone structure and flexible membrane constituting the wing are known to play a critical role in aerodynamic performance, the relationship has never been robustly quantified. Characterization of the sensitivity between preci...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/ab3e2a
更新日期:2019-09-24 00:00:00
abstract::Monodispersed iron phosphate hollow microspheres with a high degree of crystallization were prepared through a facile in situ deposition method using rape pollen grains as a biotemplate. The functional group on the surface of the pollen grains could adsorb Fe(3+), which provided the nucleation sites for growth of iron...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/5/1/016005
更新日期:2010-03-01 00:00:00
abstract::The Venus flytrap uses bistability, the structural characteristic of its leaf, to actuate the leaf's rapid closing motion for catching its prey. This paper presents a flytrap-inspired robot and novel actuation mechanism that exploits the structural characteristics of this structure and a developable surface. We focus ...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/9/3/036004
更新日期:2014-09-01 00:00:00
abstract::Most insects with smooth or hairy adhesive pads have very little problems in attaching to smooth substrates. A careful selection of surface roughness, however, can effectively limit the contact area of the adhesive organs with the surface. In comparison to conventional toxin-based insect repelling methods, biologicall...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aad061
更新日期:2018-07-31 00:00:00
abstract::Bats display a wide variety of behaviors that require different amounts of aerodynamic force. To control and modulate aerodynamic force, bats change wing kinematics, which, in turn, may change the power required for wing motion. There are many kinematic mechanisms that bats, and other flapping animals, can use to incr...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/9/2/025008
更新日期:2014-06-01 00:00:00
abstract::The flight performance of insects is strongly affected by the deformation of the wing during a stroke cycle. Many insects therefore use both active and passive mechanisms to control the deformation of their wings in flight. Several studies have focused on the wing kinematics, and plenty is known about the mechanism of...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/10/5/056003
更新日期:2015-08-20 00:00:00
abstract::Swimming fish and flying insects use the flapping of fins and wings to generate thrust. In contrast, microscopic organisms typically deform their appendages in a wavelike fashion. Since a flapping motion with two degrees of freedom is able, in theory, to produce net forces from a time-periodic actuation at all Reynold...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/9/1/016001
更新日期:2014-03-01 00:00:00
abstract::In this paper, we study the behavioral response of rats to a robotic rat during multi-rat interaction. Experiments are conducted in an open-field where a robotic rat called WR-5 is put together with three laboratory rats. WR-5 is following one rat (target), while avoiding the other two rats (outside observers) during ...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/10/5/056011
更新日期:2015-09-28 00:00:00
abstract::Nano-structured colorful zinc oxide (ZnO) replicas were produced using the wings of the Ideopsis similis butterfly as templates. The ZnO replicas we obtained exhibit iridescence, which was clearly observed under an optical microscope (OM). Field emission scanning electron microscope analysis shows that all the microst...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/1/3/003
更新日期:2006-09-01 00:00:00
abstract::In this paper, we describe the first steps in the design of a synthetic biological system based on the use of genetically modified bacteria to detect elevated pressures in soils and respond by cementing soil particles. Such a system might, for example, enable a self- constructed foundation to form in response to load ...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aabe15
更新日期:2018-05-25 00:00:00
abstract::Civil structures, such as buildings and bridges, are constantly at risk of failure due to external environmental loads, such as earthquakes or strong winds. To minimize the effects of these loads, active feedback control systems have been proposed but such systems still face numerous challenges which impede their wide...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/ab033b
更新日期:2019-02-27 00:00:00
abstract::The noseleaf and pinnae of horseshoe bats (Rhinolophus ferrumequinum) have both been shown to actively deform during biosonar operation. Since these baffle structures directly affect the properties of the animals biosonar system, this work mimics horseshoe bat sonar system with the goal of developing a platform to stu...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aac788
更新日期:2018-06-26 00:00:00
abstract::Silk produced by the silkworm Bombyx mori is an attractive material because of its luster, smooth and soft texture, conspicuous mechanical strength, good biocompatibility, slow biodegradation, and carbon neutral synthesis. Silkworms have been domesticated and bred for production of better quality and quantity of silk,...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章,评审
doi:10.1088/1748-3190/aabbe9
更新日期:2018-05-15 00:00:00
abstract::Structural hierarchy and complex 3D architecture are characteristics of biological photonic designs that are challenging to reproduce in synthetic materials. Top-down lithography allows for designer patterning of arbitrary shapes, but is largely restricted to planar 2D structures. Self-assembly techniques facilitate e...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/8/4/045004
更新日期:2013-12-01 00:00:00
abstract::While insect grooming has been observed and documented for over one hundred years, we present the first quantitative analysis of this highly dynamic process. Pollinating insects, like honey bees, purposely cover themselves with millions of pollen particles that, if left ungroomed, would make sensing and controlled fli...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aa5c6e
更新日期:2017-03-23 00:00:00
abstract::Puncturing blood vessels during percutaneous intervention in minimally invasive brain surgery can be a life threatening complication. Embedding a forward looking sensor in a rigid needle has been proposed to tackle this problem but, when using a rigid needle, the procedure needs to be interrupted and the needle extrac...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aaa6f4
更新日期:2018-02-16 00:00:00
abstract::Locomotion at low Reynolds numbers encounters stringent physical constraints due to the dominance of viscous over inertial forces. A variety of swimming microorganisms has demonstrated diverse strategies to generate self-propulsion in the absence of inertia. In particular, ameboid and euglenoid movements exploit shape...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aba2b9
更新日期:2020-07-03 00:00:00
abstract::A novel dual-differential four-bar flapping mechanism that can accurately emulate insect wing kinematics in all three degrees of freedom (translation, rotation and stroke plane deviation) is developed. The mechanism is specifically designed to be simple and scalable such that it can be utilized on an insect-based flap...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/7/3/036017
更新日期:2012-09-01 00:00:00
abstract::Fiber reinforced elastomeric enclosures (FREEs) are soft pneumatic actuators that can contract and generate forces upon pressurization. Typical engineering applications utilize FREEs in their straight cylindrical configuration and derive actuation displacement and forces from their ends. However, there are several ins...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3190/aab19c
更新日期:2018-04-18 00:00:00
abstract::Films of conducting polymers when used as electrodes in an electrolytic solution oxidize and reduce under the flow of anodic and cathodic currents, respectively. The electrochemical reactions induce conformational movements of the chains, generation or destruction of free volume and interchange of ions and solvent wit...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/3/3/035004
更新日期:2008-09-01 00:00:00
abstract::Previous research on the flexible structure of flapping wings has shown an improved propulsion performance in comparison to rigid wings. However, not much is known about this function in terms of power efficiency modification for flapping wing energy devices. In order to study the role of the flexible wing deformation...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/8/3/036011
更新日期:2013-09-01 00:00:00
abstract::This work pursues a feedforward control algorithm for high-speed legged locomotion over uneven terrain. Being able to rapidly negotiate uneven terrain without visual or a priori information about the terrain will allow legged systems to be used in time-critical applications and alongside fast-moving humans or vehicles...
journal_title:Bioinspiration & biomimetics
pub_type: 杂志文章
doi:10.1088/1748-3182/9/3/036018
更新日期:2014-09-01 00:00:00