Neuronal imaging with ultrahigh dynamic range multiphoton microscopy.

abstract：:Noise pollution is increasing globally, and as oceans are excellent conductors of sound, this is a major concern for marine species reliant on sound for key life functions. Loud, impulsive sounds from seismic surveys have been associated with impacts on many marine taxa including mammals, crustaceans, cephalopods, and...

journal_title：Scientific reports

authors： Kavanagh AS,Nykänen M,Hunt W,Richardson N,Jessopp MJ

更新日期：2019-12-16 00:00:00

abstract：:Birds have a highly specialized and efficient digestive system, but when this system originated remains uncertain. Here we report six gastric pellets attributable to the recently discovered 160-million-year-old troodontid dinosaur Anchiornis, which is among the key taxa for understanding the transition to birds. The g...

journal_title：Scientific reports

authors： Zheng X,Wang X,Sullivan C,Zhang X,Zhang F,Wang Y,Li F,Xu X

更新日期：2018-09-21 00:00:00

abstract：:Bif-1 is a membrane-curvature inducing protein that is implicated in the regulation of autophagy and tumorigenesis. Here, we report that Bif-1 plays a critical role in regulating lipid catabolism to control the size of lipid droplets and prevent the development of obesity and insulin resistance upon aging or dietary c...

journal_title：Scientific reports

authors： Liu Y,Takahashi Y,Desai N,Zhang J,Serfass JM,Shi YG,Lynch CJ,Wang HG

更新日期：2016-02-09 00:00:00

abstract：:The Martian outflow channels comprise some of the largest known channels in the Solar System. Remote-sensing investigations indicate that cataclysmic floods likely excavated the channels ~3.4 Ga. Previous studies show that, in the southern circum-Chryse region, their flooding pathways include hundreds of kilometers of...

journal_title：Scientific reports

authors： Rodriguez JAP,Baker VR,Liu T,Zarroca M,Travis B,Hui T,Komatsu G,Berman DC,Linares R,Sykes MV,Banks ME,Kargel JS

更新日期：2019-02-25 00:00:00

abstract：:Carbon nanofibers were widely utilized to improve microwave absorption properties since they are a promising lightweight candidate. Adjustable conductive nanostructures of carbon nanofibers were synthesized by electrospinning technique. The conductive network is controlled by the polyvinyl pyrrolidone (PVP) content du...

journal_title：Scientific reports

authors： Lv J,Gu W,Cui X,Dai S,Zhang B,Ji G

更新日期：2019-03-12 00:00:00

abstract：:The purpose of this study was to investigate a preclinical spectral photon-counting CT (SPCCT) prototype compared to conventional CT for pulmonary imaging. A custom-made lung phantom, including nodules of different sizes and shapes, was scanned with a preclinical SPCCT and a conventional CT in standard and high-resolu...

journal_title：Scientific reports

authors： Kopp FK,Daerr H,Si-Mohamed S,Sauter AP,Ehn S,Fingerle AA,Brendel B,Pfeiffer F,Roessl E,Rummeny EJ,Pfeiffer D,Proksa R,Douek P,Noël PB

更新日期：2018-11-26 00:00:00

abstract：:A bubble merged from two parent bubbles with different size tends to be placed closer to the larger parent. This phenomenon is known as the coalescence preference. Here we demonstrate that the coalescence preference can be blocked inside a densely packed cluster of bubbles. We utilized high-speed high-resolution X-ray...

journal_title：Scientific reports

authors： Kim Y,Lim SJ,Gim B,Weon BM

更新日期：2015-01-13 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Aponte-Santamaría C,Fischer G,Båth P,Neutze R,de Groot BL

更新日期：2017-12-05 00:00:00

abstract：:In clinical pathology, stent interposition is used to treat vascular disease but can lead to restenosis. Drug-eluting stents (DES) are most commonly used to suppress restenosis but can also have side effects. Therefore, we investigated the anti-proliferative effect and its possible target in vitro and in vivo. We foun...

journal_title：Scientific reports

authors： Lee JJ,Lee JH,Yim NH,Han JH,Ma JY

更新日期：2017-08-15 00:00:00

abstract：:Dravet syndrome is the prototype of SCN1A-mutation associated epilepsies. It is characterised by prolonged seizures, typically provoked by fever. We describe the evaluation of an SCN1A mutation in a child with early-onset temperature-sensitive seizures. The patient carries a heterozygous missense variant (c3818C > T; ...

journal_title：Scientific reports

authors： Peters C,Rosch RE,Hughes E,Ruben PC

更新日期：2016-09-01 00:00:00

abstract：:Here we provide, at least to our knowledge, the first evidence that aripiprazole (APPZ) in the water blunts the stress response of exposed fish in a concentration ten times lower than the concentration detected in the environment. Although the mechanism of APPZ in the neuroendocrine axis is not yet determined, our res...

journal_title：Scientific reports

authors： Barcellos HH,Kalichak F,da Rosa JG,Oliveira TA,Koakoski G,Idalencio R,de Abreu MS,Giacomini AC,Fagundes M,Variani C,Rossini M,Piato AL,Barcellos LJ

更新日期：2016-11-22 00:00:00

abstract：:Genome-wide studies on high-altitude adaptation have received increased attention as a classical case of organismal evolution under extreme environment. However, the current genetic understanding of high-altitude adaptation emanated mainly from autosomal analyses. Only a few earlier genomic studies paid attention to t...

journal_title：Scientific reports

authors： Wu H,Liu YH,Wang GD,Yang CT,Otecko NO,Liu F,Wu SF,Wang L,Yu L,Zhang YP

更新日期：2016-10-07 00:00:00

abstract：:Archaeologically defined Upper Palaeolithic (UP, 45,000-10,000 years ago) "cultures" are often used as proxies to designate fossil populations. While recent genomic studies have partly clarified the complex relationship between European UP "cultures" and past population dynamics, they leave open numerous questions reg...

journal_title：Scientific reports

authors： Mounier A,Heuzé Y,Samsel M,Vasilyev S,Klaric L,Villotte S

更新日期：2020-12-14 00:00:00

abstract：:Short term treatment with low doses of glucocorticoid analogues has been shown to ameliorate neurological symptoms in Ataxia-Telangiectasia (A-T), a rare autosomal recessive multisystem disease that mainly affects the cerebellum, immune system, and lungs. Molecular mechanisms underlying this clinical observation are u...

journal_title：Scientific reports

authors： Pozzi E,Giorgio E,Mancini C,Lo Buono N,Augeri S,Ferrero M,Di Gregorio E,Riberi E,Vinciguerra M,Nanetti L,Bianchi FT,Sassi MP,Costanzo V,Mariotti C,Funaro A,Cavalieri S,Brusco A

更新日期：2020-11-19 00:00:00

abstract：:Lavender (Lavandula angustifolia) is an important economic plant because of the value of its essential oil (EO). The Yili Valley in Xinjiang has become the largest lavender planting base in China. However, there is a lack of research on the gene expression regulation of EO biosynthesis and metabolism in local varietie...

journal_title：Scientific reports

authors： Guo D,Kang K,Wang P,Li M,Huang X

更新日期：2020-04-24 00:00:00

abstract：:Online financial markets can be represented as complex systems where trading dynamics can be captured and characterized at different resolutions and time scales. In this work, we develop a methodology based on non-negative tensor factorization (NTF) aimed at extracting and revealing the multi-timescale trading dynamic...

journal_title：Scientific reports

authors： Kobayashi T,Sapienza A,Ferrara E

更新日期：2018-07-25 00:00:00

abstract：:Despite recent advances in drug delivery, the targeted treatment of unhealthy cells or tissues continues to remain a priority. In cancer (much like other pathologies), delivery vectors are designed to exploit physical and biological features of unhealthy tissues that are not always homogenous across the disease. In so...

journal_title：Scientific reports

authors： Evangelopoulos M,Yazdi IK,Acciardo S,Palomba R,Giordano F,Pasto A,Sushnitha M,Martinez JO,Basu N,Torres A,Hmaidan S,Parodi A,Tasciotti E

更新日期：2020-01-13 00:00:00

abstract：:Facial mimicry has been suggested to be a behavioral index for emotional empathy. The present study is the first to investigate the link between facial muscle activity and empathy for pain by facial electromyographic (EMG) recording while observers watched videos depicting real-life painful events. Three types of visu...

journal_title：Scientific reports

authors： Sun YB,Wang YZ,Wang JY,Luo F

更新日期：2015-12-09 00:00:00

abstract：:B cell derived induced pluripotent stem cells (BiPSCs) were recently established from peripheral blood B cells by the simultaneous transfection of Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) and C/EBPα using a Sendai virus vector. Here, using a different method, we established BiPSCs with immunoglobulin heavy chain (...

journal_title：Scientific reports

authors： Kawamura F,Inaki M,Katafuchi A,Abe Y,Tsuyama N,Kurosu Y,Yanagi A,Higuchi M,Muto S,Yamaura T,Suzuki H,Noji H,Suzuki S,Yoshida MA,Sasatani M,Kamiya K,Onodera M,Sakai A

更新日期：2017-05-10 00:00:00

abstract：:Taking advantage of the magnetoelectric and its inverse effect, this article demonstrates strain-mediated magnetoelectric write and read operations simultaneously in Co60Fe20B20/Pb(Mg1/3Nb2/3)0.7Ti0.3O3 heterostructures based on a pseudo-magnetization µ ≡ mx2 - my2. By applying an external DC-voltage across a (011)-cu...

journal_title：Scientific reports

authors： Shen T,Ostwal V,Camsari KY,Appenzeller J

更新日期：2020-07-01 00:00:00

abstract：:Anti-EGFR antibodies are effective in therapies for late-stage colorectal cancer (CRC); however, many tumours are unresponsive or develop resistance. We performed genomic analysis of intrinsic and acquired resistance to anti-EGFR therapy in prospectively collected tumour samples from 25 CRC patients receiving cetuxima...

journal_title：Scientific reports

authors： Bray SM,Lee J,Kim ST,Hur JY,Ebert PJ,Calley JN,Wulur IH,Gopalappa T,Wong SS,Qian HR,Ting JC,Liu J,Willard MD,Novosiadly RD,Park YS,Park JO,Lim HY,Kang WK,Aggarwal A,Kim HC,Reinhard C

更新日期：2019-10-25 00:00:00

abstract：:Sediment accretion (burial) and nutrient enrichment occur concurrently in lacustrine wetlands, but the role of these two aspects of sedimentation on macrophyte performance has rarely been examined. Here, we investigated the concurrent effects of sediment accretion and nutrient enrichment on the growth and propagation ...

journal_title：Scientific reports

authors： Chen X,Liao Y,Xie Y,Wu C,Li F,Deng Z,Li X

更新日期：2017-01-05 00:00:00

abstract：:Crop wild relatives are valuable resources for future genetic improvement. Here, we report the de novo genome assembly of Musa itinerans, a disease-resistant wild banana relative in subtropical China. The assembled genome size was 462.1 Mb, covering 75.2% of the genome (615.2Mb) and containing 32, 456 predicted protei...

journal_title：Scientific reports

authors： Wu W,Yang YL,He WM,Rouard M,Li WM,Xu M,Roux N,Ge XJ

更新日期：2016-08-17 00:00:00

abstract：:Here we show that electrical tuning of the sensitivity of chemitransistor sensors, namely field-effect-transistors (FETs) exploiting nano/mesostructured sensing materials, can be used to effectively address two chief problems of state-of-the-art gas sensors, specifically fabrication reliability and degradation by agin...

journal_title：Scientific reports

authors： Lazzerini GM,Strambini LM,Barillaro G

更新日期：2013-01-01 00:00:00

abstract：:Unwanted clots lead to heart attack and stroke that result in a large number of deaths. Currently available anticoagulants have some drawbacks including their non-specific actions. Therefore novel anticoagulants that target specific steps in the coagulation pathway are being sought. Here we describe the identification...

journal_title：Scientific reports

authors： Girish VM,Kini RM

更新日期：2016-08-25 00:00:00

abstract：:A reliable method for the diagnosis of minimal cardiac ischemia would meet a strong demand for the sensitive diagnosis of coronary artery disease in cardiac stress testing and risk stratification in patients with chest pain but unremarkable ECGs and biomarkers. We hypothesized that platelets accumulate early on in isc...

journal_title：Scientific reports

authors： Ziegler M,Alt K,Paterson BM,Kanellakis P,Bobik A,Donnelly PS,Hagemeyer CE,Peter K

更新日期：2016-12-02 00:00:00

abstract：:Myocyte Enhancer Factor 2 (MEF2) mediates cardiac remodelling in heart failure (HF) and is also a target of β-adrenergic signalling, a front-line treatment for HF. We identified global gene transcription networks involved in HF with and without β-blocker treatment. Experimental HF by transverse aortic constriction (TA...

journal_title：Scientific reports

authors： Tobin SW,Hashemi S,Dadson K,Turdi S,Ebrahimian K,Zhao J,Sweeney G,Grigull J,McDermott JC

更新日期：2017-06-30 00:00:00

abstract：:Engineered nanomaterials hold great promise for the future development of innovative products but their adverse health effects are a major concern. Recent studies have indicated that certain nanomaterials, including carbon nanotubes (CNTs), may be carcinogenic. However, the underlying mechanisms behind their potential...

journal_title：Scientific reports

authors： Voronkova MA,Luanpitpong S,Rojanasakul LW,Castranova V,Dinu CZ,Riedel H,Rojanasakul Y

更新日期：2017-09-14 00:00:00

abstract：:Orb2 is a functional amyloid that plays a key role in Drosophila long-term memory formation. Orb2 has two isoforms that differ in their N-termini. The N-terminus of the A isoform (Orb2A) that precedes its Q-rich prion-like domain has been shown to be important for Orb2 aggregation and long-term memory. However, beside...

journal_title：Scientific reports

authors： Cervantes SA,Bajakian TH,Soria MA,Falk AS,Service RJ,Langen R,Siemer AB

更新日期：2016-12-06 00:00:00

abstract：:Leiomyomas, adenomyosis, and endometriosis are reported to be risk factors for endometrial carcinoma (EC), and adenomyosis and endometriosis also for ovarian carcinoma (OC). We aimed to describe the prevalence of these conditions in EC patients with or without an OC diagnosis, and to investigate their relationship wit...

journal_title：Scientific reports

authors： Johnatty SE,Stewart CJR,Smith D,Nguyen A,O' Dwyer J,O'Mara TA,Webb PM,Spurdle AB

更新日期：2020-02-27 00:00:00