Prognostic significance of serum procalcitonin in patients with unresectable hepatocellular carcinoma treated with transcatheter arterial chemoembolization: A retrospective analysis of 509 cases.

Abstract:

:Although procalcitonin (PCT) is a valid marker for early diagnosis of bacterial infections, its accuracy in hepatocellular carcinoma (HCC) patients is unknown. The aim of this study was to investigate the prognostic significance of PCT in patients with unresectable HCC treated with transcatheter arterial chemoembolization (TACE).A total of 509 patients with unresectable HCC initially treated with TACE were enrolled in this retrospective study. According to quartile of the PCT values, all patients were divided into 4 groups. Overall survival (OS) was evaluated with the Kaplan-Meier method. Significant difference was estimated with the Log rank method. Univariate and multivariate analyses were used for evaluating the significance of the prognostic factor.The median follow-up period was 18 months and there were significant differences in the survival rates between the 4 groups. The HR (95% CI) for all-cause mortality comparing patients with PCT Quartile2-4 to patient with Quartile1 (HR = 1.00) were 1.353 (1.023-1.791), 1.799 (1.354-2.390), 1.960 (1.455-2.639), respectively, (P < .001). PCT level was an important prognostic factor for predicting the prognosis of patients with unresectable HCC treated with TACE.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Shen H,Zheng S,Chen R,Jin X,Xu X,Jing C,Lin J,Zhang J,Zhang M,Zhang L,Xie X,Guo K,Ren Z,Lin S,Zhang B

doi

10.1097/MD.0000000000007438

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

e7438

issue

28

eissn

0025-7974

issn

1536-5964

pii

00005792-201707140-00018

journal_volume

96

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • A Comparison of Uremic Pruritus in Patients Receiving Peritoneal Dialysis and Hemodialysis.

    abstract::Uremic pruritus is common and bothersome in patients receiving either peritoneal dialysis (PD) or hemodialysis (HD). To date, the preferred dialysis modality regarding the alleviation of uremic pruritus remains controversial. We conducted this cross-sectional study to compare the prevalence, intensity, and characteris...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002935

    authors: Wu HY,Peng YS,Chen HY,Tsai WC,Yang JY,Hsu SP,Pai MF,Lu HM,Chiang JF,Ko MJ,Wen SY,Chiu HC

    更新日期:2016-03-01 00:00:00

  • Body mass index and the risk of low femoral artery puncture in coronary angiography under fluoroscopy guidance.

    abstract::The inferior border of the femoral head (IBFH) is widely used as a landmark in femoral artery puncture during invasive coronary angiography (ICA). However, application of this technique can be challenging especially in obese patients. This study was performed to investigate the association between body mass index (BMI...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010070

    authors: Kim M,Kim MA,Kim HL,Lee WJ,Lim WH,Seo JB,Kim SH,Zo JH

    更新日期:2018-03-01 00:00:00

  • Hand metastasis in a patient with cervical cancer: A case report.

    abstract:INTRODUCTION:Acrometastasis is infrequent and generally indicates a wider spread of metastasis with poor prognosis. The diagnosis is challenging, as it might mimic an infectious, inflammatory, or metabolic disease. Acrometastasis are most commonly found in patients with lung, gastrointestinal, kidney, and breast cancer...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020897

    authors: Gallardo-Alvarado L,Ramos AA,Perez-Montiel D,Ramirez-Morales R,Diaz E,Leon DC

    更新日期:2020-07-02 00:00:00

  • Incidence of injuries among amateur badminton players: A cross-sectional study.

    abstract::The main aims of this study were, firstly, to investigate the frequency, location, and severity of injuries in amateur badminton players, and then to determine risk factors that may be associated with a higher incidence of injuries.A cross-sectional study, composed of 150 players drawn from the 2018 BWF European Senio...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019785

    authors: Marchena-Rodriguez A,Gijon-Nogueron G,Cabello-Manrique D,Ortega-Avila AB

    更新日期:2020-05-01 00:00:00

  • Hepatoid adenocarcinoma of fallopian tube: A case report and review of the literature.

    abstract:RATIONALE:Hepatoid adenocarcinoma (HAC) of the fallopian tubes is a rare malignant tumor in the female reproductive system. PATIENT CONCERNS:An 81-year-old Chinese woman presented with an elevated serum alpha-fetoprotein (AFP) level. DIAGNOSIS:Positron emission tomography-computed tomography (PET-CT) scan revealed a ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014534

    authors: Li M,Yang K,Wang P

    更新日期:2019-03-01 00:00:00

  • A novel dermato-pulmonary syndrome associated with MDA-5 antibodies: report of 2 cases and review of the literature.

    abstract::Melanoma differentiation-associated protein 5 (MDA-5) is a novel autoantibody frequently characterized by interstitial lung disease and a distinct cutaneous phenotype with palmar papules, ulceration, and rash. Virtually all patients have underlying dermatomyositis, but many lack the characteristic clinical myopathy as...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0b013e3182606f0b

    authors: Chaisson NF,Paik J,Orbai AM,Casciola-Rosen L,Fiorentino D,Danoff S,Rosen A

    更新日期:2012-07-01 00:00:00

  • Woven coronary anomaly leading to silent myocardial infarction: A case report.

    abstract:RATIONALE:Woven coronary artery is an extremely unusual congenital anomaly with unknown etiology. Because of normal flow after anomalous segment, this anomaly is considered to be benign. PATIENT CONCERNS:A 51-year-old man was admitted to our hospital with exertional dyspnea that he had experienced for half a year. Wov...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008302

    authors: Xing Z,Tang L,Huang J,Hu X

    更新日期:2017-11-01 00:00:00

  • Pulmonary function changes and its influencing factors after preoperative brace treatment in patients with adolescent idiopathic scoliosis: A retrospective case-control study.

    abstract:BACKGROUND:The aim of the study was to retrospectively investigate the changes in pulmonary function and its influencing factors in patients with adolescent idiopathic scoliosis (AIS) undergoing preoperative brace treatment or not. METHODS:Total 237 AIS patients (43 boys, 194 girls) who underwent operations and had a ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005088

    authors: Ran B,Fan Y,Yuan F,Guo K,Zhu X

    更新日期:2016-10-01 00:00:00

  • Intra-arterial chemotherapy for unilateral advanced intraocular retinoblastoma: Results and short-term complications.

    abstract::Intra-arterial chemotherapy (IAC) has become an essential technique for the management of advanced intraocular retinoblastoma (RB). In this study, the aim of this article is to describe the clinical results and the short-term complications of IAC performed in our hospital.We retrospectively analyzed patients with newl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012676

    authors: Wang L,Han M,Zhao J,Wu C,Wang Z,Li J,Song D,Wang C,Yang Y,Guo L

    更新日期:2018-10-01 00:00:00

  • Leiomyosarcoma in the mandible: A rare case report.

    abstract::Leiomyosarcoma (LMS) is a malignancy which very rarely occurs in maxillofacial location, and the course of the disease is not very characteristic.In this case report, we present a 58-year-old female patient with a painless tumor of the left angle of the mandible causing slight asymmetry of the face. She also reported ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004011

    authors: Lewandowski B,Brodowski R,Pakla P,Stopyra W,Gawron I

    更新日期:2016-07-01 00:00:00

  • The natural history of symptomatic recurrent bacteriuria in women.

    abstract::In 23 adult women having uncomplicated recurrent urinary tract infections treated with 10 days of appropriate antibiotic for each infection, the following findings were noted. 1. The attack rate was 0.17 infections per month. 2. 94% of infections has associated symptoms. 3. 73% of symptomatic episodes had an associate...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:

    authors: Kraft JK,Stamey TA

    更新日期:1977-01-01 00:00:00

  • Assessment of left ventricular function in chronic alcoholics by real-time three-dimensional echocardiography.

    abstract::Chronic alcohol consumption may lead to progressive cardiac dysfunction. The aim of this study was to evaluate the feasibility of using real-time 3-dimensional echocardiography (3DE) on assessing left ventricular (LV) function in chronic alcoholics.We classified 92 male alcoholics into mild, moderate, and severe group...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006033

    authors: Wang Y,Shan G,Shen J,Zhou Q,Tan B,Liu Y,Luo R,Zhao S,Bi W,Yao F,Li G

    更新日期:2017-02-01 00:00:00

  • Clinicopathological features and prognostic factors of young patients with surgically treated liver cancer.

    abstract::This article compares the clinical characteristics and prognosis of young patients in different age groups with liver cancer (LC). In this retrospective study, we searched the Surveillance, Epidemiology, and End Results population-based database and identified 2641 patients who had been diagnosed with LC between 1988 ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000684

    authors: Zhang W,Jiang R,Hou J,Sun B

    更新日期:2015-03-01 00:00:00

  • Association of Bisphenol A Exposure With Hypertension and Early Macrovascular Diseases in Chinese Adults: A Cross-Sectional Study.

    abstract::Bisphenol A (BPA) is an environmental endocrine disruptor that has been associated with cardiovascular outcomes in previous observational studies. We aimed to examine the relationships of urinary BPA levels with hypertension and early macrovascular diseases.This is a cross-sectional study. From June through August 200...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001814

    authors: Wang T,Xu M,Xu Y,Lu J,Li M,Chen Y,Wang W,Lai S,Bi Y,Ning G

    更新日期:2015-10-01 00:00:00

  • Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children: A cross-sectional study.

    abstract::Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles' force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007572

    authors: Martín Lorenzo T,Albi Rodríguez G,Rocon E,Martínez Caballero I,Lerma Lara S

    更新日期:2017-07-01 00:00:00

  • Positron Emission Tomography With 18F-Fluorodeoxyglucose in Patients With Sickle Cell Acute Chest Syndrome.

    abstract::The acute chest syndrome (ACS) is the main cause of mortality among adult patients with sickle cell disease (SCD). Its pathophysiology is still unclear. Using positron emission tomography (PET) with F-fluorodeoxyglucose [18F-fluorodeoxyglucose (F-FDG)], we explored the relationship between regional lung density and lu...

    journal_title:Medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/MD.0000000000000821

    authors: de Prost N,Sasanelli M,Deux JF,Habibi A,Razazi K,Galactéros F,Meignan M,Maître B,Brun-Buisson C,Itti E,Dessap AM

    更新日期:2015-05-01 00:00:00

  • Trimethoprim-sulfamethoxazole-induced hyponatremia in an elderly lady with Achromobacter xylosoxidans pneumonia: Case report and insights into mechanism.

    abstract:RATIONALE:Hyponatremia occurs frequently in the hospital setting and may be attributable to a host of etiologies. Drugs are frequently implicated. Trimethoprim-sulfamethoxazole (TMP/SMX) represents a well-recognized pharmacologic precipitant of drug-induced hyponatremia, with several reports extant in the retrievable l...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020746

    authors: Ghali MGZ,Kim MJ

    更新日期:2020-08-14 00:00:00

  • A systematic review of randomized controlled trials of the Wenyang Huoxue method in treating diabetic peripheral neuropathy.

    abstract:OBJECTIVE:To assess the efficacy and safety of the Wenyang Huoxue method for patients with diabetic peripheral neuropathy. METHODS:A systematic literature search was performed using 7 databases: PUBMED, EMBASE, the Chinese National Knowledge Infrastructure, Wanfang, Chinese BioMedical, and the VIP Chinese Science and ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017618

    authors: Deng Z,Wang M,Fan YH,Huang R,Rao Y,Mai X,Liu M

    更新日期:2019-10-01 00:00:00

  • Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature.

    abstract::Bacillus Calmette-Guérin (BCG) is the most effective intravesical immunotherapy for superficial bladder cancer. Although generally well tolerated, BCG-related infectious complications may occur following instillation. Much of the current knowledge about this complication comes from single case reports, with heterogene...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000000119

    authors: Pérez-Jacoiste Asín MA,Fernández-Ruiz M,López-Medrano F,Lumbreras C,Tejido Á,San Juan R,Arrebola-Pajares A,Lizasoain M,Prieto S,Aguado JM

    更新日期:2014-10-01 00:00:00

  • Characteristics of carcinogenic HPV genotypes in North China Plain and the association with cervical lesions.

    abstract::Human papillomavirus (HPV) infection is a crucial health problem and caused substantial malignancy diseases among female worldwide. We aim to investigate the distribution of HPV subtype and the status of cervical cancer and precancerous lesions caused by HPV infection in North China Plain population. A total of 61,870...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017087

    authors: Liu L,Wang D,Dong H,Jin C,Jiang L,Song H,Jin C,Wang T,Shi C,Yang L,Wang Y

    更新日期:2019-09-01 00:00:00

  • Effective treatment using itraconazole combined with terbinafine in the treatment of nasal sporotrichosis: A case report.

    abstract:RATIONALE:Sporotrichosis is a subacute or chronic infection caused by sporothrix schenckii complex. The misdiagnosis rate of sporotrichosis is very high. Fungal microscopic examination and timely culture help us make an accurate diagnosis and treatment. We observed that combined treatments are more effective than monot...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017155

    authors: Guo K,Wang S,Wang Z,Zhang L

    更新日期:2019-09-01 00:00:00

  • Hemodialysis Is Associated With Increased Peripheral Artery Occlusive Disease Risk Among Patients With End-Stage Renal Disease: A Nationwide Population-Based Cohort Study.

    abstract::To investigate the effect of different dialysis modalities on the incidence of peripheral artery occlusive disease (PAOD) among patients with end-stage renal disease (ESRD) in a large population-based cohort study. The cohort study included 26,927 ESRD patients who underwent hemodialysis (17,737 patients, hemodialysis...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001164

    authors: Lin CS,Chen SJ,Sung CC,Lin CL,Lin SH,Cheng SM,Wang IK,Huang WS,Kao CH

    更新日期:2015-07-01 00:00:00

  • Treatment of a Simple Bone Cyst Using a Cannulated Hydroxyapatite Pin.

    abstract::Simple bone cysts (SBCs) are benign bone tumors. However, the treatment of SBCs remains controversial because of their healing rate and the invasiveness of surgery. The purpose of the present study was to evaluate the treatment of SBCs using a cannulated hydroxyapatite (HA) pin.A total of 43 patients (35 males, 8 fema...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000001027

    authors: Shirai T,Tsuchiya H,Terauchi R,Tsuchida S,Mizoshiri N,Ikoma K,Fujiwara H,Miwa S,Kimura H,Takeuchi A,Hayashi K,Yamamoto N,Kubo T

    更新日期:2015-06-01 00:00:00

  • No associations exists between red blood cell distribution width and serum uric acid in both sexes.

    abstract::The aim of this study was to determine whether there was a significant association between red blood cell distribution width (RDW) and uric acid (UA) in a large Chinese population.This was a cross-sectional study with an enrollment of 80,298 ostensibly healthy participants (48,971 males, 31,327 females) during the per...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012707

    authors: Zhang C,Meng Z,Li X,Liu M,Ren X,Zhu M,He Q,Zhang Q,Song K,Jia Q,Chen Q

    更新日期:2018-10-01 00:00:00

  • Perioperative Standard Oral Nutrition Supplements Versus Immunonutrition in Patients Undergoing Colorectal Resection in an Enhanced Recovery (ERAS) Protocol: A Multicenter Randomized Clinical Trial (SONVI Study).

    abstract::To compare immunonutrition versus standard high calorie nutrition in patients undergoing elective colorectal resection within an Enhanced Recovery After Surgery (ERAS) program.Despite progress in recent years in the surgical management of patients with colorectal cancer (ERAS programs), postoperative complications are...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/MD.0000000000003704

    authors: Moya P,Soriano-Irigaray L,Ramirez JM,Garcea A,Blasco O,Blanco FJ,Brugiotti C,Miranda E,Arroyo A

    更新日期:2016-05-01 00:00:00

  • Infantile-onset Pompe disease with neonatal debut: A case report and literature review.

    abstract:RATIONALE:Infantile-onset Pompe disease, also known as glycogen storage disease type II, is a progressive and fatal disorder without treatment. Enzyme replacement therapy with recombinant human acid alpha-glucosidase (GAA) enhances survival; however, the best outcomes have been achieved with early treatment. PATIENT C...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000009186

    authors: Martínez M,Romero MG,Guereta LG,Cabrera M,Regojo RM,Albajara L,Couce ML,Pipaon MS

    更新日期:2017-12-01 00:00:00

  • Probiotics, prebiotics, and synbiotics for the treatment of asthma: Protocol for a systematic review.

    abstract:BACKGROUND:Asthma is a common chronic disease with heavy burden. The number of asthma patients may continue to grow in the next 10 years. Existing conventional treatments have problems in which a small number of patients do not respond, often accompanied by side effects, or are too expensive. Probiotics, prebiotics, an...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017840

    authors: Huang L,Guo J,Li W,Jiang M,Wang F,Kang J,Liu T,Gu X

    更新日期:2019-11-01 00:00:00

  • Effect of high-quality nursing on alleviating depression and anxiety in patients with thyroid cancer during perioperative period: A protocol for systematic review.

    abstract:BACKGROUND:This study will assess the effect of high-quality nursing (HQN) on alleviating depression and anxiety (DA) in patients with thyroid cancer (TC) during perioperative period (PPP). METHODS:We will search the following electronic databases (MEDLINE, EMBASE, PsycINFO, Cochrane Library, CINAHL, Web of Science, C...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023018

    authors: Cui Y,Li YX

    更新日期:2020-11-06 00:00:00

  • Ultrasound is highly specific in diagnosing compensated cirrhosis in chronic hepatitis C patients in real world clinical practice.

    abstract::Ultrasound is routinely used during the evaluation of liver cirrhosis. Inter-observer variability is considered a major drawback. This retrospective study investigated the accuracy of ultrasound in diagnosing compensated cirrhosis (i.e., modified Knodell F3, F4) in chronic hepatitis C (CHC) patients in real world clin...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016270

    authors: Yen YH,Kuo FY,Chen CH,Hu TH,Lu SN,Wang JH,Hung CH

    更新日期:2019-07-01 00:00:00

  • Misinterpretation of carbon dioxide monitoring because of deadspace of heat and moisture exchanger with a filter in pediatric anesthesia: A case report.

    abstract:RATIONALE:When patients are intubated and treated with mechanical ventilation, the upper respiratory tract is bypassed by the flow of dry and cold air. To prevent disturbances of airway homeostasis, a heat and moisture exchanger filter (HMEF) has been applied to breathing circuit. PATIENT CONCERNS:A 4-month-old male i...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012158

    authors: Lee JE,Kim JH,Kim SO

    更新日期:2018-08-01 00:00:00