Abstract：
:Water-soluble protein content (WSPC) is a critical factor in both soybean protein quality and functionality. However, the underlying genetic determinants are unclear. Here, we used 219 soybean accessions and 152 recombinant inbred lines genotyped with high-density markers and phenotyped in multi-environments to dissect the genetic architectures of WSPC and protein content (PC) using single- and multi-locus genome-wide association studies. In the result, a total of 32 significant loci, including 10 novel loci, significantly associated with WSPC and PC across multi-environments were identified, which were subsequently validated by linkage mapping. Among these loci, only four exhibited pleiotropic effects for PC and WSPC, explaining the low correlation coefficient between the two traits. The largest-effect WSPC-specific loci, GqWSPC8, was stably identified across all six environments and tagged to a linkage disequilibrium block comprising two promising candidate genes AAP8 and 2 S albumin, which might contribute to the high level of WSPC in some soybean varieties. In addition, two genes, Glyma.13G123500 and Glyma.13G194400 with relatively high expression levels at seed development stage compared with other tissues were regarded as promising candidates associated with the PC and WSPC, respectively. Our results provide new insights into the genetic basis of WSPC affecting soybean protein quality and yield.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhang D,Lü H,Chu S,Zhang H,Zhang H,Yang Y,Li H,Yu Ddoi
10.1038/s41598-017-04685-7subject
Has Abstractpub_date
2017-07-11 00:00:00pages
5053issue
1issn
2045-2322pii
10.1038/s41598-017-04685-7journal_volume
7pub_type
杂志文章abstract：:Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in t...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-020-64636-7
更新日期：2020-05-13 00:00:00
abstract：:Cold atmospheric plasma (CAP), a technology based on quasi-neutral ionized gas at low temperatures, is currently being evaluated as a new highly selective alternative addition to existing cancer therapies. Here, we present a first attempt to identify the mechanism of CAP action. CAP induced a robust ~2-fold G2/M incre...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep00636
更新日期：2012-01-01 00:00:00
abstract：:Archaeological evidence suggests that dogs were introduced to the islands of Oceania via Island Southeast Asia around 3,300 years ago, and reached the eastern islands of Polynesia by the fourteenth century AD. This dispersal is intimately tied to human expansion, but the involvement of dogs in Pacific migrations is no...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27363-8
更新日期：2018-06-14 00:00:00
abstract：:Endothelial cells respond to changes in subendothelial stiffness by altering their migration and mechanics, but whether those responses are due to transcriptional reprogramming remains largely unknown. We measured traction force generation and also performed gene expression profiling for two endothelial cell types gro...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-54336-2
更新日期：2019-12-03 00:00:00
abstract：:The Sigma-1 receptor (S1R) is known to play a protective role in the central nervous system including the retina. A major barrier for understanding the underlying mechanism is an ambiguity of S1R subcellular localizations. We thus conducted the first electron microscopy (EM) study of S1R subcellular distribution in th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10689
更新日期：2015-06-02 00:00:00
abstract：:The lack of vaccines and antiviral treatment, along with the increasing number of cases of Zika virus (ZIKV) and Chikungunya virus (CHIKV) infections, emphasize the need for searching for new therapeutic strategies. In this context, the marine brown seaweed Canistrocarpus cervicornis has been proved to hold great anti...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65357-7
更新日期：2020-05-19 00:00:00
abstract：:Diabetes mellitus (DM) during pregnancy can result in fetal overgrowth, likely due to placental dysfunction, which has health consequences for the infant. Here we test our prediction from previous work using a placental cell line that high glucose concentrations affect placental lipid metabolism. Placentas from women ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-50626-x
更新日期：2019-10-01 00:00:00
abstract：:3-D modeling of coupled thermo-hydro-mechanical (THM) processes in enhanced geothermal systems using the control volume finite element code was done. In a first, a comparative analysis on the effects of coupled processes, operational parameters and reservoir parameters on heat extraction was conducted. We found that s...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14273-4
更新日期：2017-12-06 00:00:00
abstract：:High salinity frequently causes inhibition and even failure in anaerobic digestion. To explore the impact of increasing NaCl concentrations on biogas production, and reveal the microbial community variations in response to high salinity stress, the Illumina high-throughput sequencing technology was employed. The resul...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01298-y
更新日期：2017-04-25 00:00:00
abstract：:Rab small GTPases play key roles in intracellular membrane trafficking. Rab33a promotes axon outgrowth of cultured rat hippocampal neurons by mediating the anterograde axonal transport of Golgi-derived vesicles and the concomitant exocytosis of these vesicles at the growth cone. However, the functions of Rab33 in vivo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38468-5
更新日期：2019-02-12 00:00:00
abstract：:Foliar fungi of silver birch (Betula pendula) in an experimental Finnish forest were investigated across a gradient of tree species richness using molecular high-throughput sequencing and visual macroscopic assessment. We hypothesized that the molecular approach detects more fungal taxa than visual assessment, and tha...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep41801
更新日期：2017-02-02 00:00:00
abstract：:The transition to agriculture was a key event in human history. The extent to which this transition is associated with biological changes in different world regions remains debated. Cultural and osteological records in Lower Nubia throughout the Holocene have been interpreted as a result of in situ differentiation or ...
journal_title：Scientific reports
pub_type： 历史文章,杂志文章
doi：10.1038/srep31040
更新日期：2016-08-09 00:00:00
abstract：:We provide a proof for the necessity of quantizing fundamental interactions demonstrating that a quantum version is needed for any non trivial conservative interaction whose strength depends on the relative distance between two objects. Our proof is based on a consistency argument that in the presence of a classical f...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47844-8
更新日期：2019-08-06 00:00:00
abstract：:Increased ultraviolet B (UVB) radiation due to global change can affect plant growth and metabolism. Here, we evaluated the capacity of quinoa to resist under short acute UVB irradiation. Quinoa was daily exposed for 30 or 60 min to 1.69 W m-2 UVB. The results showed that 30 min exposure in 9 d-course did not cause se...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18710-2
更新日期：2018-01-10 00:00:00
abstract：:Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli and Listeria innocua biofilms. Both technologies were efficient in controlling...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81977-z
更新日期：2021-01-27 00:00:00
abstract：:Advanced structural characterisation techniques which are rapid to use, non-destructive and structurally definitive on the nanoscale are in demand, especially for a detailed understanding of extended-defects and their influence on the properties of materials. We have applied the electron backscatter diffraction (EBSD)...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11187-z
更新日期：2017-09-07 00:00:00
abstract：:Histone deacetylases (HDACs) can enzymatically transferred acetyl functional group from protein or lysine residues of histone, so they can regulate the expression of lots of genes. Now HDACs are used as drug targets and many HDAC inhibitors (HDACis) were approved for cancer therapy or in clinical trials. However, the ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39487-6
更新日期：2019-02-20 00:00:00
abstract：:Type 2 C protein phosphatases (PP2Cs) represent the major group of protein phosphatases in plants and play important roles in various plant processes. In this study, 94 MtPP2C genes were identified from Medicago truncatula and further phylogenetically classified into 13 subfamilies, as supported by exon-intron organiz...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-29627-9
更新日期：2018-08-27 00:00:00
abstract：:Previous studies have established that an increased Th-9 response creates a hostile environment for nematode parasites. Given that IL-23, a cytokine required for maintenance of the IL-17-secreting phenotype, has inhibitory effects on IL-9 production, we hypothesized that reducing circulating IL-23 by treatment with an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26194-x
更新日期：2018-05-17 00:00:00
abstract：:Microalgae are versatile organisms capable of converting CO2, H2O, and sunlight into fuel and chemicals for domestic and industrial consumption. Thus, genetic modifications of microalgae for enhancing photosynthetic productivity, and biomass and bio-products generation are crucial for both academic and industrial appl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30620
更新日期：2016-07-28 00:00:00
abstract：:While the feasibility of transpapillary drug delivery has previously been established, localized transport via the mammary ducts may be improved with tailored drug delivery formulations. The objective of this study was to investigate the impact of nanoemulsion encapsulation on transpapillary delivery in vitro. Nanoemu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-48144-x
更新日期：2019-08-14 00:00:00
abstract：:In this decade coherent X-ray diffraction imaging has been demonstrated to reveal internal structures of whole biological cells and organelles. However, the spatial resolution is limited to several tens of nanometers due to the poor scattering power of biological samples. The challenge is to recover correct phase info...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08074
更新日期：2015-01-28 00:00:00
abstract：:Nature provides remarkable examples of mass-produced microscale particles with structures and chemistries optimized by evolution for particular functions. Synthetic chemical tailoring of such sustainable biogenic particles may be used to generate new multifunctional materials. Herein, we report a facile method for the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73615-x
更新日期：2020-10-06 00:00:00
abstract：:Dramatic and rapid changes in cell shape are perhaps best exemplified by phagocytes, such as neutrophils. These cells complete the processes of spreading onto surfaces, and phagocytosis within 100 s of stimulation. Although these cell shape changes are accompanied by an apparent large increase in cell surface area, th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09761-6
更新日期：2017-08-29 00:00:00
abstract：:Lipidised analgesic peptide prodrugs self-assemble into peptide nanofibers; with the nanofiber morphology protecting the peptide from plasma degradation and improving therapeutic efficacy. Extending this learning, we hypothesised that a self-assembling lipidized peptide arginine vasopressin (AVP) receptor agonist, tha...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-64070-9
更新日期：2020-04-29 00:00:00
abstract：:Control of pathogens arising from humans, livestock and wild animals can be enhanced by genome-based investigation. Phylogenetically classifying and optimal construction of these genomes using short sequence reads are key to this process. We examined the mammal-infecting unicellular parasite Leishmania adleri belongin...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43747
更新日期：2017-03-03 00:00:00
abstract：:Halobacteria, a class of Euryarchaeota are extremely halophilic archaea that can adapt to a wide range of salt concentration generally from 10% NaCl to saturated salt concentration of 32% NaCl. It consists of the orders: Halobacteriales, Haloferaciales and Natriabales. Pan-genome analysis of class Halobacteria was don...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-77723-6
更新日期：2020-12-03 00:00:00
abstract：:Advances in lab-on-a-chip (LOC) devices have led to significant improvements in the on-chip manipulation, separation, sorting, and isolation of particles and cells. Among various LOC-based approaches such as inertia-based methods, acoustophoresis, and magnetophoresis, the planar-slanted-electrode dielectrophoresis (DE...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68699-4
更新日期：2020-07-16 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-020-63944-2
更新日期：2020-04-22 00:00:00
abstract：:Stem and progenitor cells are the critical units for tissue maintenance, regeneration, and repair. The activation of regenerative events in response to tissue injury has been correlated with mobilization of tissue-resident progenitor cells, which is functional to the wound healing process. However, until now there has...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16574
更新日期：2015-11-12 00:00:00
