Abstract:
:There is an increased interest in extending surgical criteria for pancreatic cancer by performing pancreaticoduodenectomy (PD) combined with portal vein (PV) or superior mesenteric vein (SMV) resection and reconstruction for borderline resectable patients. However, whether this procedure suitable for elderly patients remains unclear. Here, we studied cases of pancreatic cancer treatment in our medical center to evaluate feasibility and safety of this procedure in the elderly.Eighty-three patients 65 years of age or older who underwent PD from January 2009 to March 2014 were divided into 2 groups: PD only (Group A, 52 cases), and PD combined with PV/SMV resection and reconstruction (Group B, 31 cases). Surgical outcomes and survival rates were compared between groups. Information regarding preoperative, intraoperative and postoperative conditions, and follow-up visits were provided. The outcomes of postoperative complications and survival rates were investigated.No difference in the preoperative data was detected between 2 groups with the exception that the serum albumin level was significantly lower in Group B (P = .013), indicating more deteriorating health conditions in this group. Although intraoperative time and blood loss were higher in Group B (P < .001 and P = .048, respectively), the overall postoperative complications and survival curve showed no statistical differences between 2 groups with one exception in that there was higher incidence of intractable diarrhea in Group B (P = .034). The symptoms, however, resolved later on with conservative treatment. The median survival time for patients in this study was comparable to other reported PD treatments. There was zero postoperative mortality in both groups.PD combined with PV/SMV treatment did not lead to increased morbidity and motility in elderly patients 65 years of age and above. This procedure could provide a promising opportunity for borderline resectable elderly pancreatic cancer patients.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Fang JZ,Lu CD,Wu SD,Huang J,Zhou Jdoi
10.1097/MD.0000000000007335subject
Has Abstractpub_date
2017-07-01 00:00:00pages
e7335issue
27eissn
0025-7974issn
1536-5964pii
00005792-201707070-00022journal_volume
96pub_type
杂志文章相关文献
MEDICINE文献大全abstract:BACKGROUND:To investigate the relationship between intracerebral hemorrhage hematoma expansion with low serum calcium level. METHODS:We will search the following electronic bibliographic databases: MEDLINE, Embase, PubMed, The Cochrane Library, and Web of Science. All sources have to be searched from the earliest date...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018844
更新日期:2020-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000006423.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000006811
更新日期:2017-04-28 00:00:00
abstract:RATIONALE:Iatrogenic chylous leakage (CL) is a rare but potentially life-threatening complication after neck surgery. In cirrhotic patient, the massive CL is even more intractable and extremely dangerous due to portal hypertension. PATIENTS CONCERNS:A 54-year-old liver cirrhotic patient had milky fluid leakage from le...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009103
更新日期:2017-12-01 00:00:00
abstract::Periodontitis is a systemic and chronic inflammatory disease associated with multiple physical conditions. Distress and depression are other problems affecting the progression of periodontitis. However, the causal relationship between depression and periodontitis has not been adequately investigated. This aim of this ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002347
更新日期:2015-12-01 00:00:00
abstract::To evaluate the timing, feasibility, and necessity of early laparoscopic cholecystectomy (LC) in the management of patients with acute calculous cholecystitis complicated with hepatic dysfunction.The clinical data of 60 patients with acute calculous cholecystitis complicated with hepatic dysfunction treated from Janua...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020239
更新日期:2020-06-12 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002306.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000481354.70978.fe
更新日期:2016-03-03 00:00:00
abstract:BACKGROUND:It has been reported that the cluster of differentiation 14 (CD14) gene -159C/T variant may be associated with asthma risk. However, some studies yielded conflicting results. Therefore, a comprehensive meta-analysis was designed to assess the precise association. METHODS:A systematic search in PubMed, Embas...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000004959
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Gaucher disease (GD) is caused by a deficiency in the lysosomal enzyme glucocerebrosidase. Enzyme replacement therapy (ERT) is recommended for clinical improvement. METHODS:The efficacy and safety of a new imiglucerase, Abcertin, were assessed in 7 Egyptian patients with treatment-naïve type 1 GD. Each pati...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000008492
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:The best treatment option for patients with post-hemorrhagic hydrocephalus (PHH) remains controversial. The objective of the current meta-analysis is to systematically evaluate the long-term outcomes of patients with PHH treated by ventriculoperitoneal shunt (VPS) and lumboperitoneal shunt (LPS). METHODS:We...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021640
更新日期:2020-08-07 00:00:00
abstract::It is shown that there are strong associations between nonalcoholic fatty liver disease (NAFLD) and endothelial dysfunction. The aim of our study was to reveal whether steatosis or fibrosis score is more important in the development of endothelial dysfunction in patients with NAFLD in a prospective manner.This cross-s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003280
更新日期:2016-04-01 00:00:00
abstract::AIDS-associated Kaposi's sarcoma (AIDS-KS) caused by human herpes virus 8 (HHV-8) is the most severe and resistant form of KS tumor. Our aim was to verify whether there is an association between HHV-8 variability and development of AIDS-KS in Brazil by comparing the HHV-8 variability between individuals without and wi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005291
更新日期:2016-11-01 00:00:00
abstract::Posthepatectomy liver failure (PHLF) is the main cause of perioperative death, and liver cirrhosis is one of the most important risk factors for PHLF. Spleen stiffness (SS) is a novel ultrasonic indicator for liver cirrhosis and portal hypertension, however, it is not clear that whether it has a significant influence ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015458
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:This systematic review aims to explore the effectiveness and safety of extracorporeal shock-wave therapy (ESWT) for patients with frozen shoulder. METHODS:The sources of Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Web of Science,...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000014506
更新日期:2019-02-01 00:00:00
abstract::Laparoscopic inguinal herniorrhaphy has been well established for the management of primary and recurrent inguinal hernias. Single-incision laparoscopic surgery (SILS) has now been accepted as a less invasive alternative to conventional laparoscopic surgery. However, commercially available access devices for SILS had ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021787
更新日期:2020-08-21 00:00:00
abstract::The objective of this study was to develop a venous computed tomography (CT)-based radiomics model to predict the lymph node metastasis (LNM) in patients with non-small cell lung cancer (NSCLC). A total of 411 consecutive patients with NSCLC underwent tumor resection and lymph node (LN) dissection from January 2018 to...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020074
更新日期:2020-05-01 00:00:00
abstract::With the rapid increase in the incidence of mental disorders and mental issues, psychiatry has become one of the fastest growing clinical medical disciplines. Development priorities and research foci in this field have evolved over different periods.All the articles in 10 psychiatric journals with the highest impact f...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007349
更新日期:2017-06-01 00:00:00
abstract::Concomitant influenza and cryptococcal infections are rare. Herein, we describe an unusual case of an avian influenza A (H7N9) infection with several severe mixed bacterial infections and systemic super-infection with Cryptococcus neoformans presenting as ventilator-associated pneumonia (VAP) and bloodstream infection...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000015544
更新日期:2019-05-01 00:00:00
abstract:RATIONALE:Football players are at high risk for lower extremity injuries because they turn on an axis of rotation, turn while decelerating, and repeatedly jump and land. One of the most common sites of injury is the knee. PATIENT CONCERNS:A 25-year-old amateur university football player with pain in the knee medial ar...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010973
更新日期:2018-06-01 00:00:00
abstract::Since body fatness is a convincing risk factor for endometrial cancer, dietary fat intake was speculated to be associated with endometrial cancer risk. However, epidemiological studies are inconclusive. We aimed to conduct a meta-analysis to assess the associations between dietary fat intake and endometrial cancer ris...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000004121
更新日期:2016-07-01 00:00:00
abstract::We aim to screen the mutations of 3 hearing loss (HL) genes (GJB2, SLC26A4, and 12S rRNA) in 71 cases with nonsyndromic hearing loss (NSHL) using microarray and SNPscan, and identify the roles of nonhotspot mutation of these genes in the screening of NSHL. Seventy-one cases with moderate or severe neurosensory deafnes...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007149
更新日期:2017-06-01 00:00:00
abstract::Diabetes mellitus (DM) is prevalent in patients with pancreatic cancer and tends to improve after tumor resection. However, the glycemic response of non-pancreatic cancer patients after surgery has not been examined in detail. We aimed to investigate the changes in glucose metabolism in patients with pancreatic cancer...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010590
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Shexiang Baoxin Pills (SBP) is widely used for the treatment of unstable angina pectoris (UAP) in China. However, the clinical evidence on the efficacy of SBP for the treatment of UAP is not well concluded. METHODS:Seven electronic databases will be searched for eligible studies: MEDLINE, EMBASE, The Cochra...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017119
更新日期:2019-09-01 00:00:00
abstract::Hypotonia, particularly of the masticatory and oropharyngeal muscles, is 1 of the main characteristics of Down Syndrome (DS), resulting in impaired speech, chewing and swallowing. Moreover, the complete or partial obstruction of the airways during sleep may occur due to hypotonia of the tongue, leading to snoring and ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019904
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Danshen injection (DSI) is a traditional Chinese medicine preparation extracted from Danshen (Salvia miltiorrhiza), which has the functions of promoting blood circulation and removing blood stasis. Heart failure (HF) is a complex cardiovascular disease, always leading to frequent onset and hospitalization, d...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015636
更新日期:2019-05-01 00:00:00
abstract:INTRODUCTION:Systemic Bartonella spp. infections are being increasingly reported in association with complex medical presentations. Individuals with frequent arthropod exposures or animal contact appear to be at risk for acquiring long standing infections with Bartonella spp. CASE REPORT:This case report describes inf...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010465
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:The study aims to evaluate the effectiveness and safety of Tuina for children with myopia. METHODS:The following electronic databases will be searched from establishment to July 2019: Cochrane Library, MEDLINE, EMBASE, Web of Science, Springer, World Health Organization International Clinical Trials Registr...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018342
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Hepatectomy and additional common bile duct exploration are required for the treatment of left-sided hepatolithiasis (LSH). METHODS:Eligible LSH patients (n = 62) scheduled for open left lateral segmentectomy or left hemihepatectomy with intraoperative biliary exploration via the left hepatic duct orifice (...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000009643
更新日期:2018-01-01 00:00:00
abstract::This meta-analysis aimed to compare the short- and long-term outcomes in patients undergoing combined coronary endarterectomy and coronary artery bypass grafting (CE + CABG) versus isolated CABG, and particularly to examine subgroup patients with high-risk profile and patients with diffuse disease in the left anterior...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000001781
更新日期:2015-10-01 00:00:00
abstract::High-dose cyclophosphamide has long been used as an anticancer agent, a conditioning regimen for hematopoietic stem cell transplantation, and a potent immunosuppressive agent in autoimmune diseases including aplastic anemia. High-dose cyclophosphamide is highly toxic to lymphocytes but spares hematopoietic stem cells ...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0b013e318210e685
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:With the progress of surgical techniques and instruments, various minimally invasive surgical therapies were developed to treat benign prostatic hyperplasisa (BPH). However, the efficacy and safety of different transurethral procedures for the treatment of BPH are still undefined. METHOD:A systematic search...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013360
更新日期:2018-12-01 00:00:00