Income generated by women treated with magnetic resonance imaging-based brachytherapy: A simulation study evaluating the macroeconomic benefits of implementing a high-end technology in a public sector healthcare setting.

Abstract:

PURPOSE:To estimate the difference in income generated if all women presenting in our institute over a 5-year period were treated with MRI-based image-guided brachytherapy (MR-IGBT) instead of conventional radiograph-based brachytherapy (CR-BT). METHODS AND MATERIALS:Outcome data from 463 patients (94 treated with MR-IGBT) treated in our institute was used to simulate cumulative women-days of work and cumulative income over 5 years for 5526 patients expected to be treated in this period. The average daily income for a woman was derived from the National Sample Survey Organization (NSSO) survey data. Outcomes from both unmatched and propensity score-matched data sets were simulated. RESULTS:The cumulative income in 5 years ranged between Rs 101-168 million if all patients presenting at our institute underwent MR-IGBT. The simulated excess income ranged from Rs 4-45 million after 5 years, which represented 6-66% of the expenditure incurred for acquiring the required equipment and manpower for practicing exclusive MR-IGBT. CONCLUSIONS:Using outcome data from a prospective cohort of patients treated with MR-IGBT in our institute, we demonstrated that significant economic gains may be realized if MR-IGBT was used instead of CR-BT.

journal_name

Brachytherapy

journal_title

Brachytherapy

authors

Chakraborty S,Mahantshetty U,Chopra S,Lewis S,Hande V,Gudi S,Krishnatry R,Engineer R,Shrivastava SK

doi

10.1016/j.brachy.2017.05.003

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

981-987

issue

5

eissn

1538-4721

issn

1873-1449

pii

S1538-4721(17)30356-2

journal_volume

16

pub_type

杂志文章
  • In vivo dosimetry in gynecological applications-A feasibility study.

    abstract:PURPOSE:To investigate the feasibility of in vivo dosimetry using microMOSFET dosimeters in patients treated with brachytherapy using two types of gynecological applicators. METHODS AND MATERIALS:In this study, a microMOSFET was placed in an empty needle of an Utrecht Interstitial Fletcher applicator or MUPIT (Martine...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2017.04.240

    authors: Van Gellekom MPR,Canters RAM,Dankers FJWM,Loopstra A,van der Steen-Banasik EM,Haverkort MAD

    更新日期:2018-01-01 00:00:00

  • Californium-252 neutron brachytherapy combined with external beam radiotherapy for esophageal cancer: long-term treatment results.

    abstract:PURPOSE:The aim of this study was to retrospectively observe and analyze the long-term treatment outcomes for a total of 952 esophageal cancer patients who were treated with (252)Cf neutron brachytherapy (NBT) in combination with external beam radiotherapy (EBRT). METHODS AND MATERIALS:From November 2001 to March 2012...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2014.03.004

    authors: Liu H,Wang Q,Wan X,Jia X,Liu B,Wang CK

    更新日期:2014-09-01 00:00:00

  • Radiation protection and dosimetry issues for patients with prostate cancer after I-125 low-dose-rate brachytherapy permanent implant.

    abstract:PURPOSE:The aim of this work was to analyze the exposure rates measured in the proximity of patients who underwent prostate low-dose-rate brachytherapy with I-125 implant. Effective doses to relatives and to population were computed to estimate the time to reach radioprotection dose constraints. METHODS AND MATERIALS:...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2020.09.003

    authors: Licciardello T,Feliciani G,Mazzotti G,Mostacci D,Sarnelli A,Menghi E

    更新日期:2021-01-01 00:00:00

  • Feasibility report for retreatment of locally recurrent head-and-neck cancers by combined brachy-chemotherapy using frameless image-guided 3D interstitial brachytherapy.

    abstract:PURPOSE:Brachytherapy re-irradiation may offer an alternative re-treatment of recurrent head-and-neck cancer even after previous full dose radiation therapy. The purposes of this study were to determine the feasibility and accuracy of frameless image-guided interstitial needle implantation. METHODS AND MATERIALS:Betwe...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2005.02.001

    authors: Krempien RC,Grehn C,Haag C,Straulino A,Hensley FW,Kotrikova B,Hofele C,Debus J,Harms W

    更新日期:2005-01-01 00:00:00

  • A detailed examination of the difference between planned and treated margins in 125I permanent prostate brachytherapy.

    abstract:PURPOSE:To determine whether potential extraprostatic extension (EPE) of prostate adenocarcinoma is covered by the prescribed dose when permanent 125I implants are planned with a 5-mm treatment margin. METHODS AND MATERIALS:The postimplant dosimetry of 60 consecutive 125I prostate implants was analyzed to determine wh...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2003.09.002

    authors: Patel AB,Waterman FM,Dicker AP

    更新日期:2003-01-01 00:00:00

  • Is stereotactic CyberKnife radiotherapy or multicatheter HDR brachytherapy the better option dosimetrically for accelerated partial breast irradiation?

    abstract:OBJECTIVE:To compare dosimetrically the stereotactic CyberKnife (CK) therapy and multicatheter high-dose-rate (HDR) brachytherapy (BT) for accelerated partial breast irradiation (APBI). METHODS:Treatment plans of 25 patients treated with CK were selected, and additional plans using multicatheter HDR BT were created on...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2020.10.003

    authors: Fröhlich G,Mészáros N,Smanykó V,Stelczer G,Herein A,Polgár C,Major T

    更新日期:2020-11-18 00:00:00

  • CT-based interstitial brachytherapy in advanced gynecologic malignancies: outcomes from a single institution experience.

    abstract:PURPOSE:To evaluate the clinical outcomes of women receiving a "short" course of high-dose-rate gynecologic interstitial brachytherapy (HDR-ISBT) boost with CT-based 3D planning. METHODS AND MATERIALS:Forty-seven women with no prior radiation received HDR-ISBT from August 2004 to February 2012. The mean external beam ...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2014.02.001

    authors: D'Souza D,Wiebe E,Patil N,Sugimoto A,Prefontaine M,Aulakh S,Whiston F,Stitt L,Surry K

    更新日期:2014-05-01 00:00:00

  • Salvage low-dose-rate brachytherapy for local recurrences after prostatectomy and adjuvant or salvage external beam irradiation: Feasibility study on five patients and literature review.

    abstract:PURPOSE:To assess the feasibility and tumor outcome of re-irradiation with low-dose-rate brachytherapy for macroscopic local recurrences after radical prostatectomy (RP) followed by adjuvant or salvage external beam radiation therapy (EBRT). METHODS AND MATERIALS:Between 2011 and 2018, five men with histologically pro...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2020.07.001

    authors: Le Roy C,Gassa F,Rouvière O,Desmettre O,Bringeon G,Charret J,Serre AA,Pommier P

    更新日期:2021-01-01 00:00:00

  • A pilot study of intraluminal brachytherapy using 125I seed strand for locally advanced pancreatic ductal adenocarcinoma with obstructive jaundice.

    abstract:PURPOSE:To investigate the safety and feasibility of intraluminal brachytherapy using 125I seed strand for locally advanced pancreatic ductal adenocarcinoma with obstructive jaundice. METHODS AND MATERIALS:From January 2010 to February 2015, 18 consecutive patients diagnosed with locally advanced, nonmetastatic, inope...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2016.05.004

    authors: Yang M,Yan Z,Luo J,Liu Q,Zhang W,Ma J,Zhang Z,Yu T,Zhao Q,Liu L

    更新日期:2016-01-01 00:00:00

  • The effect of pelvic radiotherapy on vaginal brachytherapy cylinder diameter: Implications for optimal treatment order.

    abstract:PURPOSE:To determine the factors that correlate with cylinder size in vaginal brachytherapy (VB) after hysterectomy for endometrial carcinoma. METHODS AND MATERIALS:Patients treated for endometrial cancer from January 1, 2003 to December 31, 2013 were reviewed from a single institution. Patients included underwent tot...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2016.04.391

    authors: Rakhra SS,Weaver C,Donnelly ED,Helenowski I,Prescott AE,Strauss JB

    更新日期:2016-09-01 00:00:00

  • Factors associated with the omission of androgen deprivation therapy in radiation-managed high-risk prostate cancer.

    abstract:PURPOSE:Androgen deprivation therapy (ADT) has been shown to improve survival for men with unfavorable-risk prostate cancer (PCa). We investigated the utilization and factors associated with the omission of ADT in radiation-managed high-risk PCa. METHODS AND MATERIALS:We used the National Cancer Database to identify m...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2016.07.001

    authors: Chen YW,Muralidhar V,Mahal BA,Nezolosky MD,Beard CJ,Choueiri TK,Hoffman KE,Martin NE,Orio PF,Sweeney CJ,Feng FY,Trinh QD,Nguyen PL

    更新日期:2016-01-01 00:00:00

  • Salvage high-dose-rate brachytherapy for esophageal cancer in previously irradiated patients: A retrospective analysis.

    abstract:PURPOSE:To evaluate outcomes after exclusive salvage high-dose-rate (HDR) intraluminal esophageal brachytherapy given to previously irradiated patients with recurrent esophageal cancer. METHODS AND MATERIALS:We reviewed medical records of 30 patients who were treated by salvage HDR brachytherapy for local esophageal c...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2015.02.392

    authors: Wong Hee Kam S,Rivera S,Hennequin C,Lourenço N,Chirica M,Munoz-Bongrand N,Gornet JM,Quéro L

    更新日期:2015-07-01 00:00:00

  • Morbidity and prostate-specific antigen control of external beam radiation therapy plus low-dose-rate brachytherapy boost for low, intermediate, and high-risk prostate cancer.

    abstract:PURPOSE:Dose escalation has been shown beneficial in prostate cancer. Brachytherapy (BT) provides an opportunity for dose escalation beyond what can be safely delivered using only teletherapy methods. The purpose of this study was to determine cancer control and morbidity of external beam radiation therapy (EBRT) plus ...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2009.01.002

    authors: Koontz BF,Chino J,Lee WR,Hahn CA,Buckley N,Huang S,Kim J,Reagan R,Joyner R,Anscher MS

    更新日期:2009-04-01 00:00:00

  • Preclinical study investigating the potential of low-dose-rate brachytherapy with 32P stents for the prevention of restenosis of paranasal neo-ostia.

    abstract:PURPOSE:Ostial restenosis is a common cause of failures in paranasal sinus surgery. The aim of the current study was to investigate the use of low-dose-rate brachytherapy to prevent neo-ostial restenosis in an animal model. METHODS AND MATERIALS:In 14 rabbits, maxillary neo-ostia were created and measured. One side ea...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2016.08.011

    authors: Oestreicher E,Bartsch H,Mayr D,Schubert M,Weber B,Kneschaurek P,Assmann W,Sroka R,Betz CS

    更新日期:2017-01-01 00:00:00

  • A comparative dosimetric analysis of virtual stereotactic body radiotherapy to high-dose-rate monotherapy for intermediate-risk prostate cancer.

    abstract:PURPOSE:Stereotactic body radiotherapy (SBRT) is being used with increasing frequency as definitive treatment of early stage prostate cancer. Much of the justification for its adoption was derived from earlier clinical results using high-dose-rate (HDR) brachytherapy. We determine whether HDR's dosimetry can be achieve...

    journal_title:Brachytherapy

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.brachy.2013.03.003

    authors: Spratt DE,Scala LM,Folkert M,Voros L,Cohen GN,Happersett L,Katsoulakis E,Zelefsky MJ,Kollmeier MA,Yamada Y

    更新日期:2013-09-01 00:00:00

  • Substantial lymphovascular space invasion predicts worse outcomes in early-stage endometrioid endometrial cancer.

    abstract:INTRODUCTION:Substantial as opposed to focal or no lymphovascular space invasion (LVSI) is proposed as an independent adverse prognostic factor in patients with early-stage endometrioid endometrial cancer (EEC). We reviewed outcomes of patients treated with adjuvant vaginal brachytherapy (VB) alone in a single institut...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2020.12.006

    authors: Barnes EA,Martell K,Parra-Herran C,Taggar AS,Donovan E,Leung E

    更新日期:2021-01-20 00:00:00

  • The effect of hormonal manipulation on urinary function following permanent prostate brachytherapy.

    abstract:PURPOSE:To evaluate the effect of hormonal manipulation on catheter dependency, the resolution of urinary symptomatology, and the need for postbrachytherapy transurethral/transincisional resection (TURP/TUIP). METHODS AND MATERIALS:Seven hundred sixteen consecutive patients (median follow-up, 29 months) underwent brac...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2003.12.001

    authors: Merrick GS,Butler WM,Wallner KE,Murray B,Allen Z,Lief JH,Galbreath RW

    更新日期:2004-01-01 00:00:00

  • Clinical implementation of a novel Double-Balloon single-entry breast brachytherapy applicator.

    abstract:PURPOSE:The purpose of the study was to describe the clinical utilization of a novel Double-Balloon applicator for accelerated partial breast irradiation (APBI). METHODS AND MATERIALS:The Double-Balloon single-entry breast applicator contains a single central treatment catheter, as well as four peripheral catheters th...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2017.07.015

    authors: Anderson BM,Wallace CR,De Costa AA,Das RK

    更新日期:2017-01-01 00:00:00

  • Radiation oncology and medical physicists quality assurance in British Columbia Cancer Agency Provincial Prostate Brachytherapy Program.

    abstract:PURPOSE:To describe in detail British Columbia (BC) Cancer Agency (BCCA) Provincial Prostate Brachytherapy (PB) Quality Assurance (QA) Program. METHODS AND MATERIALS:The BCCA PB Program was established in 1997. It operates as one system, unified and supported by electronic and information systems, making it a single P...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2012.03.006

    authors: Keyes M,Morris WJ,Spadinger I,Araujo C,Cheung A,Chng N,Crook J,Halperin R,Lapointe V,Miller S,Pai H,Pickles T

    更新日期:2013-07-01 00:00:00

  • Long-term efficacy and urological toxicity of low-dose-rate brachytherapy (LDR-BT) as monotherapy in localized prostate cancer.

    abstract:PURPOSE:The purpose of this study was to evaluate the incidence of late severe (≥Grade 3) urinary toxicity and the long-term efficacy after low-dose-rate brachytherapy (LDR-BT) in patients with localized prostate cancer (PCa). METHODS AND MATERIALS:During the years 1999-2008, 241 patients with PCa who underwent LDR-BT...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2019.05.005

    authors: Vuolukka K,Auvinen P,Palmgren JE,Voutilainen T,Aaltomaa S,Kataja V

    更新日期:2019-01-01 00:00:00

  • Toward a dynamic real-time intraoperative permanent prostate brachytherapy methodology.

    abstract:PURPOSE:To evaluate dosimetry and source location relative to CT-based dosimetry when performing real-time dynamic permanent prostate brachytherapy (PPB) with inverse treatment planning. METHODS AND MATERIALS:A treatment algorithm for dynamic PPB was developed using inverse treatment planning. The technique utilizes r...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/S1538-4721(03)00134-X

    authors: Potters L,Calguaru E,Thornton KB,Jackson T,Huang D

    更新日期:2003-01-01 00:00:00

  • Vaginal vault brachytherapy as sole postoperative treatment for low-risk endometrial cancer.

    abstract:PURPOSE:To evaluate the efficacy and side effect profile of adjuvant vaginal vault brachytherapy alone after hysterectomy in Stage I endometrial carcinoma. METHODS AND MATERIALS:Between 23/11/1992 and 16/05/2005, a total of 173 patients with early endometrial carcinoma treated with vaginal vault brachytherapy alone po...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2008.01.001

    authors: Chong I,Hoskin PJ

    更新日期:2008-04-01 00:00:00

  • Clinical outcome of high-dose-rate interstitial brachytherapy in vulvar cancer: A single institutional experience.

    abstract:PURPOSE:With an aim to evaluate and report high dose date interstitial brachytherapy (HDR-ISBT) in vulvar cancers, we undertook this retrospective analysis. METHODS AND MATERIALS:Histologically proven vulvar cancers treated with HDR-ISBT between 2001 and 2016 were analyzed. Radiotherapy details, clinical outcome in te...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2016.10.003

    authors: Mahantshetty U,Naga P,Engineer R,Sastri S,Ghadi Y,Upreti U,Somesan V,Kadam S,Kohle S,Deshpande D,Shrivastava SK

    更新日期:2017-01-01 00:00:00

  • Validation of the NCCN prostate cancer favorable- and unfavorable-intermediate risk groups among men treated with I-125 low dose rate brachytherapy monotherapy.

    abstract:PURPOSE:To validate the 2019 NCCN subgroups of favorable- and unfavorable-intermediate risk (IR) prostate cancer among patients treated with brachytherapy, who are underrepresented in the studies used to develop the 2019 NCCN classification. METHODS:We included all 2,705 men treated with I-125 LDR brachytherapy monoth...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2019.10.005

    authors: Tom MC,Reddy CA,Smile TD,Zhang RX,Ciezki JP,Stephans KL,Mian OY,Klein EA,Campbell S,Ulchaker J,Angermeier K,Tendulkar RD

    更新日期:2020-01-01 00:00:00

  • High-dose-rate brachytherapy for localized penile cancer: Evolution of a technique.

    abstract:PURPOSE:High-dose-rate (HDR) brachytherapy is a convenient treatment option for selected patients with T1-T2 penile squamous cell carcinoma (SCC), providing high rates of penile preservation and tumor control. We present the results of penile SCC treated with HDR brachytherapy either interstitially or via a surface mol...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2019.12.003

    authors: Marbán M,Crook J,Keyes M,Dubash R,Batchelar D

    更新日期:2020-01-01 00:00:00

  • Dose homogeneity analysis of adjuvant radiation treatment in surgically resected brain metastases: Comparison of IORT, SRS, and IMRT indices.

    abstract:PURPOSE:Although surgery remains a treatment option for symptomatic brain metastases, the need for adjuvant radiation after surgery is widely accepted as standard. Despite a multitude of randomized trials aimed at identifying the ideal radiation treatment plan for surgically resected metastases, the development of new ...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2020.11.004

    authors: Dahshan BA,Weir JS,Bice RP,Renz P,Cifarelli DT,Poplawski L,Hack J,Vargo JA,Cifarelli CP

    更新日期:2021-01-13 00:00:00

  • Impact of marital status on receipt of brachytherapy and survival outcomes in locally advanced cervical cancer.

    abstract:PURPOSE:Marriage has been associated with enhanced survival among cancer patients, but conflicting correlations have been suggested in cervical cancer. We assessed the impact of marital status on receipt of brachytherapy and survival in women with locally advanced cervical cancer. METHODS AND MATERIALS:Three thousand,...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2019.04.273

    authors: Huynh-Le MP,Klapheke A,Cress R,Mell LK,Yashar CM,Einck JP,Mundt AJ,Mayadev JS

    更新日期:2019-01-01 00:00:00

  • Optimization of prostate brachytherapy techniques with polyethylene glycol-based hydrogel spacers: A systematic review.

    abstract:PURPOSE:The objective of this overview was to critically evaluate the effect of polyethylene glycol (PEG)-based hydrogel spacers during prostate brachytherapy with regard to dosimetric and clinical benefits, as well as procedure-related toxicity. METHODS AND MATERIALS:A systematic search in the PubMed database was per...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2019.08.009

    authors: Afkhami Ardekani M,Ghaffari H

    更新日期:2020-01-01 00:00:00

  • Impact of experience and technical changes on acute urinary and rectal morbidity in low-dose prostate brachytherapy using loose seeds real-time implantation.

    abstract:PURPOSE:To assess the impact of experience and technical changes on morbidity during the first year after permanent prostate brachytherapy. METHODS AND MATERIALS:From July 2003 to May 2010, 150 patients with prostate cancer underwent low-dose iodine-125 prostate brachytherapy as a monotherapy by the same medical team ...

    journal_title:Brachytherapy

    pub_type: 杂志文章

    doi:10.1016/j.brachy.2013.04.002

    authors: Le Fur E,Malhaire JP,Nowak E,Rousseau B,Erauso A,Pene-Baverez D,Papin G,Delage F,Perrouin-Verbe MA,Fournier G,Pradier O,Valeri A

    更新日期:2013-11-01 00:00:00

  • Relationship between Day 0 dosimetric parameters and biochemical relapse-free survival in patients treated with transperineal permanent prostate interstitial brachytherapy with (125)I seeds.

    abstract:OBJECTIVES:To determine the relationship between dosimetric parameters obtained on postimplantation Day 0 and biochemical relapse-free survival (bRFS) in patients treated with (125)I transperineal interstitial permanent prostate brachytherapy (TIPPB). METHODS:Two-hundred twenty men with low-risk (n=155, 70.4%), low-vo...

    journal_title:Brachytherapy

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.brachy.2009.04.005

    authors: Garrán C,Ciérvide R,Cambeiro M,Moreno-Jiménez M,Ramos LI,Martínez-Monge R

    更新日期:2010-01-01 00:00:00