Abstract:
PURPOSE:The purpose of this study is to assess the relationship between serum glucose levels and intraocular pressure (IOP) both in subjects with impaired fasting glucose (IFG) as well as in subjects with diabetes mellitus (DM). MATERIALS AND METHODS:Data of a cross-sectional sample of 18,406 subjects who underwent routine annual screening at a tertiary medical center in 2000 to 2013 were analyzed. RESULTS:Mean (SD) age of the subjects was 46 (10) years; 68% were male. Mean (95% confidence interval) IOP measured 13.1 (13.0-13.1) mm Hg in subjects with normal glucose levels, 13.7 (13.6-13.8) mm Hg in subjects with IFG, and 14.3 (14.1-14.4) mm Hg in subjects with diabetes. The difference in IOP between subjects with normal and abnormal (DM or IFG) serum glucose levels were significant, even after adjusting for age, body mass index, and hypertension (P<0.0001). There was a positive linear correlation between serum glucose levels and IOP in both men (r=0.12; P<0.0001) and women (r=0.17; P<0.0001). For every 10 mg/dL increase in fasting serum glucose, IOP increased by 0.09 mm Hg in men and by 0.11 mm Hg in women. CONCLUSIONS:This study demonstrated that similar to subjects with DM, subjects with IFG also have IOP levels that are higher than those with normal serum glucose. Moreover, there is a direct correlation between fasting serum glucose levels and changes in IOP. These findings highlight another end-organ effect of uncontrolled glucose levels.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Cohen E,Kramer M,Shochat T,Goldberg E,Krause Idoi
10.1097/IJG.0000000000000700subject
Has Abstractpub_date
2017-07-01 00:00:00pages
652-656issue
7eissn
1057-0829issn
1536-481Xjournal_volume
26pub_type
杂志文章abstract:PURPOSE OF THE STUDY:The purpose of the study was to investigate the relationship between optical coherence tomography angiography angioflow vessel-density (PAFD) measured in the retinal nerve fiber layer in the temporal peripapillary sector and the average of the spatially corresponding superior and inferior paracentr...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000630
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To obtain retinal nerve fiber layer (RNFL) measurements by optical coherence tomography in a local, normal Hong Kong Chinese population and to identify the correlation of the measurement with age cross-sectionally. METHODS:A total of 129 normal Hong Kong Chinese volunteers of different age groups were recruite...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200212000-00004
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:To describe findings and utility of optical coherence tomography angiography (OCTA) in optic nerve head drusen (ONHD). OBSERVATIONS:A 57-year-old white man presented with a decrease in contrast sensitivity of the inferior visual field in both eyes. Clinical examination, visual fields, optical coherence tomogra...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000730
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To assess the efficacy and safety of botulinum toxin type A (BoNT-A) injection in patients suffering from intractable periorbital pain after acute angle closure glaucoma (AACG). PATIENTS AND METHODS:In this prospective randomized intervention study, 19 patients suffering from periorbital pain after an AACG att...
journal_title:Journal of glaucoma
pub_type: 杂志文章,随机对照试验
doi:10.1097/IJG.0b013e3181ca76a9
更新日期:2010-10-01 00:00:00
abstract::Primary intraocular lymphoma can cause an elevation of intraocular pressure (IOP), resulting from infiltration of the trabecular meshwork with neoplastic lymphocytes. More rarely, therapeutic procedures can induce a highly synchronised death of tumor cells, leading to congestion of the trabecular meshwork with cell de...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31827a0875
更新日期:2014-09-01 00:00:00
abstract:PRECIS:Micropulse trans-scleral cyclophotocoagulation is only moderately effective in lowering intraocular pressure and useful as an adjunct procedure to other glaucoma surgeries. There was a small risk of loss of vision, prolonged hypotony and phthisis bulbi. AIMS:To determine the efficacy and safety of a single micr...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001729
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:Recent studies have found nocturnal reductions in systemic arterial blood pressure associated with progressive visual field loss in glaucoma. Although ocular ischemia has been hypothesized to link these two phenomena, it remains unknown if perfusion of the eye is reduced during the night in patients with glauco...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract:PURPOSE:The pattern of the distribution of nerve fiber layer (NFL) thickness values across the retina may provide an early anatomic indication of glaucomatous disruption. We developed a method of analyzing polarimetry measurements that emphasizes the shape of the pattern of NFL thickness values. Sensitivity and specifi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200012000-00005
更新日期:2000-12-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of trabeculectomies performed by ophthalmology residents at a metropolitan county hospital, under the supervision of attending physicians. METHODS:A retrospective analysis of resident-performed trabeculectomies at the San Francisco General Hospital from the period of 1994 to...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000243473.59084.dd
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Pachymetry plays a crucial role in the diagnosis and management of glaucoma and corneal diseases. There have been several outbreaks of epidemic ocular infections in ophthalmology clinics worldwide with reports of viral, parasitic, and prion disease. Contact pachymetry is a possible vehicle of transmission due...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001525
更新日期:2020-08-01 00:00:00
abstract::A 28-year-old man with iridocorneal endothelial syndrome and three failed trabeculectomies received two treatments of noncontact neody-mium-YAG transscleral cyclophotocoagulation. Four weeks afterwards he presented with the clinical signs of sympathetic ophthalmia in the unoperated eye. Intense topical and subtenons c...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract:PURPOSE:To investigate the relationship between sociodemographic factors and nonpersistence with topical glaucoma medication. DESIGN:This was a retrospective, observational cohort study. PATIENTS AND METHODS:We invited glaucoma patients on medical therapy from a general ophthalmology practice to complete a standardiz...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000081
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk of developing glaucoma in patients taking systemic fluoroquinolones. METHODS:A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed wi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31829463c1
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:Our purpose was to investigate the effects of the calcium channel blocker verapamil on intraocular pressure and blood circulation in the human optic nerve head. METHODS:The effects of three different concentrations of topical verapamil (0.063%, 0.125%, and 0.25%) on intraocular pressure and optic nerve head ca...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-06-01 00:00:00
abstract:PRECIS:As the only microinvasive glaucoma surgery (MIGS) with a reusable component, the cost per procedure of endoscopic cyclophotocoagulation (ECP) diminishes with each successive use. We present a cost comparison of ECP with other MIGS devices, based on our clinical practice. PURPOSE:ECP delivers diode laser via a r...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001245
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To describe the outcome of surgical bleb revision for late-onset bleb leaks after trabeculectomy. PATIENTS AND METHODS:Appropriate cases were identified. Qualified and complete success required intraocular pressure of 21 mm Hg or less with and without glaucoma medication use, respectively. Bleb survival was de...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31821e83e6
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the factors that influence the outcome of trabectome surgery. METHODS:This was a retrospective nonrandomized study. Seventy-eight glaucoma patients (86 eyes) who underwent trabectome surgeries and were followed up for more than 12 months were included. We classified ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000743
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:Latanoprost, travoprost, and bimatoprost are prostaglandin or prostamide-type ocular hypotensive medications, all of which are effective and safe for lowering intraocular pressure (IOP). Most studies with these types of drugs have included patients mainly from European or white ethnic backgrounds; however, some...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/IJG.0b013e3181c4aeac
更新日期:2010-09-01 00:00:00
abstract::The mainstay of open-angle glaucoma surgery involves subconjunctival drainage of aqueous fluid. Insertion of the XEN Gel Stent leads to formation of a subconjunctival bleb to assist in the drainage of aqueous fluid and offers the advantage of ease and speed of insertion with conjunctival sparing over traditional surgi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001058
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To determine if laser iridotomy altered the anterior segment anatomy of patients with plateau iris configuration. METHODS:Twenty eyes of 9 female and 1 male patients were imaged using an ultrasound biomicroscope within 19 weeks before and 52 weeks after laser iridotomy. Measurements obtained included the anter...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000151687.96785.03
更新日期:2005-04-01 00:00:00
abstract:PURPOSE:To evaluate and compare outcomes of eyes that underwent laser suture lysis (LSL) after initial trabeculectomy with mitomycin C (MMC) to those that did not require such an intervention. METHODS:We reviewed the charts of consecutive patients with open-angle glaucoma who underwent initial trabeculectomy with mito...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000195929.94922.a2
更新日期:2006-02-01 00:00:00
abstract:PURPOSE:To assess the reproducibility of retinal nerve fiber layer thickness and macular thickness measurements using OCT-3. METHODS:Randomly chosen eyes of healthy individuals were scanned following pupillary dilation by two trained operators (RGO, RV) using OCT-3 (software version A1.1, Carl Zeiss Meditec, Inc., Dub...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200406000-00012
更新日期:2004-06-01 00:00:00
abstract:PURPOSE:To report a case of secondary pulmonary arterial hypertension (PAH) and the relationship of intraocular pressure (IOP) change with right ventricular diameter (RVD) and brain natriuretic peptide (BNP). METHODS:Case report. PATIENT:A 22-year-old woman with dilated and congested conjunctival and episcleral veins...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000371
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:To evaluate the reliability indices [fixation losses, false negative response rates (FN) and false positive response rates] and threshold sensitivities obtained from glaucoma patients with a Compass perimeter and to compare the same with the Humphrey field analyzer (HFA). METHODS:In a cross-sectional study, 97...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000609
更新日期:2017-03-01 00:00:00
abstract:PURPOSE:Subconjunctival mitomycin C has been used in glaucoma filtration surgery with success. A prospective, randomized, masked, placebo-controlled study was performed to evaluate whether single transconjunctival mitomycin C applied either preoperatively or postoperatively would enhance the success of filtration surge...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Many of these techniques have been adapted to investigate hemodynamic alterations, not only in glaucoma, but in diverse disorders such as diabetic retinopathy, macular degeneration, retinal dystrophies, and nonglaucomatous optic neuropathies. However, each of these techniques has limitations and there is not a single ...
journal_title:Journal of glaucoma
pub_type: 杂志文章,评审
doi:10.1097/00061198-200110001-00022
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To report the efficacy and safety of inferior 180 degrees goniosynechialysis followed by diode laser peripheral iridoplasty in the treatment of chronic angle-closure glaucoma with total synechial angle closure. METHODS:Five patients with chronic angle-closure glaucoma and total synechial angle closure whose in...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章
doi:10.1097/00061198-200010000-00007
更新日期:2000-10-01 00:00:00
abstract:PURPOSE:To evaluate aqueous levels of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in patients with branch retinal vein occlusion (BRVO) with and without normal tension glaucoma (NTG), and to assess the therapeutic efficacy of intravitreal bevacizumab (IVB) in these patients. METHODS:Sixteen eyes ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3182312047
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:We explored the risk factors for glaucoma blindness among adults aged 40 years and above with primary glaucoma in Nigeria. PARTICIPANTS AND METHODS:A total of 13,591 participants aged 40 years and above were examined in the Nigeria Blindness Survey; 682 (5.02%; 95 CI, 4.60%-5.47%) had glaucoma by ISGEO's crite...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000487
更新日期:2016-10-01 00:00:00
abstract:AIM:Dietary deficiencies in ω-3 polyunsaturated fatty acids are known to effect retinal function including retinal ganglion cell (RGC) activity, which may have implications for glaucoma. In this study we consider retinal function after dietary manipulation and intraocular pressure (IOP) stress designed to compromise RG...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e318237cac7
更新日期:2013-04-01 00:00:00