Abstract:
:As a type of primary open-angle glaucoma, normal-tension glaucoma (NTG) is a health problem that manifests itself with low intraocular pressure (IOP) levels and preserves its importance for public health care. In population-based screenings, which take the IOP levels of 21mmHg as a cut-off for the diagnosis of glaucoma, the diagnosis is usually delayed, and the treatment is started in an advanced stage by the referred ophthalmologists. NTG is associated with some autoimmune conditions and systemic diseases, such as paraproteinemia, nocturnal hypotension, and migraine. Recently, a simple and cheap test (namely the hemogram) was defined as measure of systemic inflammation, measuring the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR). A recent study displayed an altered platelet function in NTG patients. We hypothesize that an automated hemogram analysis for NLR together with IOP measurements may be used to screen NTG patients who are admitted to primary care clinics if any relationship between NTG and NLR could be demonstrated in future researches.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Atalay K,Kaldirim Erdogan H,Kirgiz A,Asik Nacaroglu Sdoi
10.1016/j.mehy.2017.04.001subject
Has Abstractpub_date
2017-06-01 00:00:00pages
54-56eissn
0306-9877issn
1532-2777pii
S0306-9877(17)30002-6journal_volume
103pub_type
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