Lifestyle Changes among ACS Survivors in Arabian Gulf Countries (Gulf COAST Registry).

abstract：:Many patients with hypertension will require multiple antihypertensive drugs to achieve blood pressure (BP) control. This double-blind study evaluated the efficacy and safety of aliskiren/amlodipine single-pill combinations (SPCs) in patients with mild-to-moderate hypertension who were non-responsive to aliskiren mono...

journal_title：Current vascular pharmacology

authors： Glorioso N,Thomas M,Troffa C,Argiolas G,Patel S,Baek I,Zhang J

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:Chlamydia pneumoniae was the first pathogen linked with carotid atherosclerotic changes and plaque rupture. Currently, other common pathogens are also under investigation as potential contributors. METHODS:A systematic review of PubMed and Scopus databases was performed. Studies evaluating the infectious ...

journal_title：Current vascular pharmacology

authors： Makris GC,Makris MC,Wilmot VV,Geroulakos G,Falagas ME

更新日期：2010-11-01 00:00:00

abstract：:Tertiary amine local anesthetics (LAs) are clinically valuable agents for controlling pain and for treating some cardiac arrhythmias. These drugs inhibit conduction of electrical activity by blocking voltage-gated sodium channels. Interestingly, LAs can influence the conduction of electrical activity in heart muscle w...

journal_title：Current vascular pharmacology

authors： Wright SN

更新日期：2003-10-01 00:00:00

abstract：:Nowadays long-term outcome of heart transplantation is limited by a peculiar type of coronary atherosclerosis, known as cardiac allograft vasculopathy (CAV). Although the exact pathogenesis of CAV remains unclear, emerging evidence indicates that the endothelium plays a significant role in the onset and progression of...

journal_title：Current vascular pharmacology

authors： Osto E,Tona F,De Bon E,Iliceto S,Cella G

更新日期：2010-03-01 00:00:00

abstract：:Visfatin is highly expressed in adipose tissue (mainly by the stromal cells), but it is also ubiquitously present in most tissues. Visfatin, which plays a role in nicotinamide adenine dinucleotide (NAD) biosynthesis, has been implicated in inflammatory states. Controversial results exist about the expression, circulat...

journal_title：Current vascular pharmacology

authors： Filippatos TD,Randeva HS,Derdemezis CS,Elisaf MS,Mikhailidis DP

更新日期：2010-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) is among the most major causes of morbidity and mortality worldwide. Great progress has been made in the management of CVD which has been influenced by the use of experimental animal models. These models provided information at cellular and molecular levels and allowed the development of t...

journal_title：Current vascular pharmacology

authors： Haidara MA,Assiri AS,Yassin HZ,Ammar HI,Obradovic MM,Isenovic ER

更新日期：2015-01-01 00:00:00

abstract：:The vascular endothelium is a monolayer of cells between the vessel lumen and the vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized from the amino acid L-arginine in endothelial cells by the constitutive calcium-calmodulin-dependent enzyme nitric oxide synthase (NOS). This subst...

journal_title：Current vascular pharmacology

authors： Tousoulis D,Kampoli AM,Tentolouris C,Papageorgiou N,Stefanadis C

更新日期：2012-01-01 00:00:00

abstract：:Neuropathies of the peripheral and autonomic nervous systems affect up to half of all people with diabetes mellitus, and are major risk factors for foot ulceration, amputation and cardiovascular dysfunction. Peripheral neuropathies manifest with either painful or painless symptoms, but many patients experience both. O...

journal_title：Current vascular pharmacology

authors： Didangelos T,Veves A

更新日期：2020-01-01 00:00:00

abstract：:The "pleiotropic" effects of statins have been the centre of a considerable research activity. Among the numerous experimental and clinical studies of this field, some focused on the effects of statins on blood pressure (BP), while others reported data on BP together with other parameters. Some of the animal or human ...

journal_title：Current vascular pharmacology

authors： Sarafidis PA,Kanaki AI,Lasaridis AN

更新日期：2007-04-01 00:00:00

abstract：:Oxidative stress has been linked to the origin and progression of cardiovascular diseases. Nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase is a multi-component, NADPH-dependent enzyme that generates superoxide anion in the presence of molecular oxygen. The enzyme has been identified and chara...

journal_title：Current vascular pharmacology

authors： Yu J,Weïwer M,Linhardt RJ,Dordick JS

更新日期：2008-07-01 00:00:00

abstract：:There is growing evidence that Rho-kinase contributes to cardiovascular disease, which has made Rho-kinase a target for the treatment of human diseases. To date, the only Rho-kinase inhibitor employed clinically in humans is fasudil, which has been used for the prevention of cerebral vasospasm and subsequent ischemic ...

journal_title：Current vascular pharmacology

authors： Satoh S,Ikegaki I,Kawasaki K,Asano T,Shibuya M

更新日期：2014-01-01 00:00:00

abstract：:This essay focuses on nine important lessons learned during more than thirty years of endothelial research. They include: the danger of hiding behind a word, the confusion generated by abbreviations, the need to define the physiological role of the response studied, the local role of endothelium- dependent responses, ...

journal_title：Current vascular pharmacology

authors： Vanhoutte PM

更新日期：2016-01-01 00:00:00

abstract：:Monoclonal antibodies have been developed to optimize treatment effects in various malignant and nonmalignant conditions, by selectively targeting key components of the underlying pathophysiologic processes. Rituximab, a chimeric anti-CD20 antibody has revolutionized treatment of malignant lymphomas, extending remissi...

journal_title：Current vascular pharmacology

authors： Ziakas PD,Kopterides P,Voulgarelis M

更新日期：2010-01-01 00:00:00

abstract：:This review provides evidence that antenatal hypoxia, which represents a significant and worldwide problem, causes prenatal programming of the lung. A general overview of lung development is provided along with some background regarding transcriptional and signaling systems of the lung. The review illustrates that ant...

journal_title：Current vascular pharmacology

authors： Papamatheakis DG,Blood AB,Kim JH,Wilson SM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the general population. The disease ranges from simple steatosis, to non-alcoholic steatohepatitis (NASH), cirrhosis and even hepatocellular carcinoma. Several drugs are used in daily clinical practice to manage the disease. However, dat...

journal_title：Current vascular pharmacology

authors： Imprialos K,Stavropoulos K,Bouloukou S,Kerpiniotis G,Karagiannis A,Doumas M

更新日期：2018-01-01 00:00:00

abstract：:Obesity is a highly prevalent complex trait that raises the risk of other chronic diseases such as type 2 diabetes, certain cancers, sleep apnea, and cardiovascular disease, and shortens lifespan. Clinical intervention studies focused on weight loss and epidemiological studies of obesity indicate that genetic variatio...

journal_title：Current vascular pharmacology

authors： Franks PW,Poveda A

更新日期：2011-07-01 00:00:00

abstract：:Platelet aggregation induced by stirring of a platelet suspension after activation by the exogenous addition of stimulants, such as ADP, epinephrine and thrombin, has long been used as a platelet function test, and for the screening of antiplatelet agents. Since platelet aggregation has been demonstrated to be mediate...

journal_title：Current vascular pharmacology

authors： Goto S

更新日期：2004-01-01 00:00:00

abstract：:Immunosuppressive drugs (ISDs) have a major impact on the development and progression of cardiac allograft vasculopathy (CAV), the main cause of cardiac allograft loss and a leading cause of death beyond the 1st post-transplant year. The influence of ISDs on the development and progression of CAV is complex. In spite ...

journal_title：Current vascular pharmacology

authors： Dandel M,Hetzer R

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Volatile Anaesthetics (VA) are commonly used worldwide for induction and/or maintenance of general anaesthesia. They act in the central nervous system to reduce sensation and motor response during surgical and invasive diagnostic procedures. VAs also have some non-anaesthetic properties in the brain when adm...

journal_title：Current vascular pharmacology

authors： Krzych LJ,Szczepanska AJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:In the era of dual antiplatelet therapy of aspirin and clopidogrel and systematic stent implantation, Glycoprotein IIb/IIIa Inhibitors (GPI), including abciximab, eptifibatide and tirofiban, proved beneficial in improving early outcome of Percutaneous Coronary Intervention (PCI), especially in higher risk cl...

journal_title：Current vascular pharmacology

authors： Rubboli A,Patti G

更新日期：2018-01-01 00:00:00

abstract：:Statins are beneficial both in the primary and secondary prevention of atherosclerotic vascular disease and acute events in a broad spectrum of patient subgroups. However, the observed clinical benefit with statin therapy is much greater than expected through the reduction of cholesterol levels alone. Clinical and exp...

journal_title：Current vascular pharmacology

authors： Yildirir A,Müderrisoglu H

更新日期：2004-10-01 00:00:00

abstract：:Although hypertension, hypercholesterolemia and diabetes mellitus (DM) are recognized as major cardio-metabolic risk factors in primary Acute Coronary Syndrome (ACS) prevention, studies focusing on secondary ACS incidence are scarce. In the present study, the association between the aforementioned factors and 10-year ...

journal_title：Current vascular pharmacology

authors： Notara V,Panagiotakos DB,Michalopoulou M,Kouvari M,Tsompanaki E,Verdi M,Vassileiou N,Kalli E,Mantas Y,Kogias Y,Stravopodis P,Papanagnou G,Zombolos S,Pitsavos C,Greecs Study Investigators.

更新日期：2016-01-01 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is a syndrome compromising the health of the mother and the fetus. Endothelial damage and reduced metabolism of the vasodilator adenosine occur and fetal hyperinsulinemia associated with deficient insulin response and a metabolic rather than mitogenic phenotype is characteristic of ...

journal_title：Current vascular pharmacology

authors： Guzmán-Gutiérrez E,Abarzúa F,Belmar C,Nien JK,Ramírez MA,Arroyo P,Salomón C,Westermeier F,Puebla C,Leiva A,Casanello P,Sobrevia L

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Kallistatin (KS) is a serine proteinase. The result of KS on 'Renal Ischemia- Reperfusion Injury' (IRI) has not clearly been researched. In this study, investigative research has been conducted to draw results on the administration of human KS on kidney response conducted within a mouse model of IRI. MATERI...

journal_title：Current vascular pharmacology

authors： Zhou S,Sun Y,Zhuang Y,Zhao W,Chen Y,Jiang B,Guo C,Zhang Z,Peng H,Chen Y

更新日期：2015-01-01 00:00:00

abstract：:Chronic kidney disease (CKD), and particularly kidney failure, is associated with accelerated atherosclerosis and approximately a 20-fold increased risk of cardiovascular death. The majority of these patients die from complications directly attributed to atherosclerosis and their life expectancy is decreased. Establis...

journal_title：Current vascular pharmacology

authors： Efstratiadis G,Tziomalos K,Mikhailidis DP,Athyros VG,Hatzitolios A

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Aging-associated vascular dysfunction promotes cardiovascular diseases. Recently, Ginkgo biloba extract (GBE) has attracted considerable attention in the prevention of aged vasculature. METHODS:This review discusses the pathophysiological alterations in aged vasculature and the underlying mechanisms of GBE ...

journal_title：Current vascular pharmacology

authors： Li X,Lu L,Chen J,Zhang C,Chen H,Huang H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The association between Paget's disease of bone (PDB) and increased cardiovascular (CV) risk has been suggested, but the literature is conflicting. OBJECTIVE:Our study aimed to evaluate two markers of CV risk [common carotid artery intima-media thickness (cIMT) and the aortic pulse wave velocity (PWV)] in p...

journal_title：Current vascular pharmacology

authors： Gaudio A,Zanoli L,Xourafa A,Rapisarda R,Catalano A,Signorelli SS,Castellino P

更新日期：2020-06-09 00:00:00

abstract：:Obstructive sleep apnoea (OSA) is characterized by repetitive interruptions of breathing, causing Chronic Intermittent Hypoxia (CIH) that can be involved in the development and progression of cardiovascular diseases. There is evidence showing a close relationship between OSA and atherosclerosis, even in patients who d...

journal_title：Current vascular pharmacology

authors： Toraldo DM,Benedetto M,Conte L,De Nuccio F

更新日期：2017-01-01 00:00:00

abstract：:A considerable amount of data supports a 1.8-7.4-fold increased mortality associated with Cushing's syndrome (CS). This is attributed to a high occurrence of several cardiovascular disease (CVD) risk factors in CS [e.g. adiposity, arterial hypertension (AHT), dyslipidaemia and type 2 diabetes mellitus (T2DM)]. Therefo...

journal_title：Current vascular pharmacology

authors： Koracevic G,Stojkovic M,Lovic D,Pavlovic M,Kostic T,Kutlesic M,Micic S,Koracevic M,Djordjevic M

更新日期：2020-01-01 00:00:00

abstract：: ...

journal_title：Current vascular pharmacology

authors： Cortese F

更新日期：2019-01-01 00:00:00