Abstract:
:The FDA has approved the small-molecule inhibitor midostaurin in combination with chemotherapy to treat acute myeloid leukemia. It is the first approved drug for the disease that specifically targets FLT3 mutations, which occur in about a quarter of all AML cases and are associated with particularly poor outcomes.
journal_name
Cancer Discovjournal_title
Cancer discoveryauthors
doi
10.1158/2159-8290.CD-NB2017-072subject
Has Abstractpub_date
2017-07-01 00:00:00pages
OF5issue
7eissn
2159-8274issn
2159-8290pii
2159-8290.CD-NB2017-072journal_volume
7pub_type
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