Giant tunnelling electroresistance in metal/ferroelectric/semiconductor tunnel junctions by engineering the Schottky barrier.

abstract：:Synthetic biology tools, such as modular parts and combinatorial DNA assembly, are routinely used to optimise the productivity of heterologous metabolic pathways for biosynthesis or substrate utilisation, yet it is well established that host strain background is just as important for determining productivity. Here we ...

journal_title：Nature communications

authors： Blount BA,Gowers GF,Ho JCH,Ledesma-Amaro R,Jovicevic D,McKiernan RM,Xie ZX,Li BZ,Yuan YJ,Ellis T

更新日期：2018-05-22 00:00:00

abstract：:The advent and growth of synthetic biology has demonstrated its potential as a promising avenue of research to address many societal needs. However, plant synthetic biology efforts have been hampered by a dearth of DNA part libraries, versatile transformation vectors and efficient assembly strategies. Here, we describ...

journal_title：Nature communications

authors： Shih PM,Vuu K,Mansoori N,Ayad L,Louie KB,Bowen BP,Northen TR,Loqué D

更新日期：2016-10-26 00:00:00

abstract：:Bacterial Type III Secretion Systems deliver effectors into host cells to manipulate cellular processes to the advantage of the pathogen. Many host targets of these effectors are found on membranes. Therefore, to identify their targets, effectors often use specialized membrane-localization domains to localize to appro...

journal_title：Nature communications

authors： Salomon D,Guo Y,Kinch LN,Grishin NV,Gardner KH,Orth K

更新日期：2013-01-01 00:00:00

abstract：:Rosemary extracts containing the phenolic diterpenes carnosic acid and its derivative carnosol are approved food additives used in an increasingly wide range of products to enhance shelf-life, thanks to their high anti-oxidant activity. We describe here the elucidation of the complete biosynthetic pathway of carnosic ...

journal_title：Nature communications

authors： Scheler U,Brandt W,Porzel A,Rothe K,Manzano D,Božić D,Papaefthimiou D,Balcke GU,Henning A,Lohse S,Marillonnet S,Kanellis AK,Ferrer A,Tissier A

更新日期：2016-10-05 00:00:00

abstract：:Dimensionality reduction is often used to visualize complex expression profiling data. Here, we use the Uniform Manifold Approximation and Projection (UMAP) method on published transcript profiles of 1484 single gene deletions of Saccharomyces cerevisiae. Proximity in low-dimensional UMAP space identifies groups of ge...

journal_title：Nature communications

authors： Dorrity MW,Saunders LM,Queitsch C,Fields S,Trapnell C

更新日期：2020-03-24 00:00:00

abstract：:Stimuli-responsive behaviors of flexible metal-organic frameworks (MOFs) make these materials promising in a wide variety of applications such as gas separation, drug delivery, and molecular sensing. Considerable efforts have been made over the last decade to understand the structural changes of flexible MOFs in respo...

journal_title：Nature communications

authors： Zhao P,Fang H,Mukhopadhyay S,Li A,Rudić S,McPherson IJ,Tang CC,Fairen-Jimenez D,Tsang SCE,Redfern SAT

更新日期：2019-03-01 00:00:00

abstract：:Pseudomonas aeruginosa, an opportunistic pathogen of humans, uses quorum sensing (QS) to regulate the production of extracellular products that can benefit all members of the population. P. aeruginosa can police QS-deficient cheaters by producing hydrogen cyanide, which is also QS regulated; however, the mechanism by ...

journal_title：Nature communications

authors： Yan H,Asfahl KL,Li N,Sun F,Xiao J,Shen D,Dandekar AA,Wang M

更新日期：2019-11-01 00:00:00

abstract：:Stimuli-responsive hydrogel actuators have promising applications in various fields. However, the typical hydrogel actuation relies on the swelling and de-swelling process caused by osmotic-pressure changes, which is slow and normally requires the presence of water environment. Herein, we report a light-powered in-air...

journal_title：Nature communications

authors： Li M,Wang X,Dong B,Sitti M

更新日期：2020-08-10 00:00:00

abstract：:The world is entering a new era of the COVID-19 pandemic in which there is an increasing call for reliable antibody testing. To support decision making on the deployment of serology for either population screening or diagnostics, we present a detailed comparison of serological COVID-19 assays. We show that among the s...

journal_title：Nature communications

authors： GeurtsvanKessel CH,Okba NMA,Igloi Z,Bogers S,Embregts CWE,Laksono BM,Leijten L,Rokx C,Rijnders B,Rahamat-Langendoen J,van den Akker JPC,van Kampen JJA,van der Eijk AA,van Binnendijk RS,Haagmans B,Koopmans M

更新日期：2020-07-06 00:00:00

abstract：:Biochemical investigation of protein phosphorylation events is limited by inefficient production of the phosphorylated and non-phosphorylated forms of full-length proteins. Here using a genomically recoded strain of E. coli with a flexible UAG codon we produce site-specific serine- or phosphoserine-containing proteins...

journal_title：Nature communications

authors： Pirman NL,Barber KW,Aerni HR,Ma NJ,Haimovich AD,Rogulina S,Isaacs FJ,Rinehart J

更新日期：2015-09-09 00:00:00

abstract：:Thymic selection shapes an appropriate T cell antigen receptor (TCR) repertoire during T cell development. Here, we show that a serine/threonine kinase, protein kinase D (PKD), is crucial for thymocyte positive selection. In T cell-specific PKD-deficient (PKD2/PKD3 double-deficient) mice, the generation of CD4 single ...

journal_title：Nature communications

authors： Ishikawa E,Kosako H,Yasuda T,Ohmuraya M,Araki K,Kurosaki T,Saito T,Yamasaki S

更新日期：2016-09-27 00:00:00

abstract：:Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of ...

journal_title：Nature communications

authors： Chacón-Duque JC,Adhikari K,Fuentes-Guajardo M,Mendoza-Revilla J,Acuña-Alonzo V,Barquera R,Quinto-Sánchez M,Gómez-Valdés J,Everardo Martínez P,Villamil-Ramírez H,Hünemeier T,Ramallo V,Silva de Cerqueira CC,Hurtado M,Villegas V

更新日期：2018-12-19 00:00:00

abstract：:Magnetic reconnection is a fundamental process in magnetized plasma where magnetic energy is converted to plasma energy. Despite huge differences in the physical size of the reconnection layer, remarkably similar characteristics are observed in both laboratory and magnetosphere plasmas. Here we present the comparative...

journal_title：Nature communications

authors： Yamada M,Chen LJ,Yoo J,Wang S,Fox W,Jara-Almonte J,Ji H,Daughton W,Le A,Burch J,Giles B,Hesse M,Moore T,Torbert R

更新日期：2018-12-06 00:00:00

abstract：:Molecular machines carry out their function by equilibrium mechanical motions in environments that are far from thermodynamic equilibrium. The mechanically equilibrated character of the trajectories of the macromolecule has allowed development of a powerful theoretical description, reminiscent of Onsager's trajectory ...

journal_title：Nature communications

authors： Astumian RD

更新日期：2019-08-23 00:00:00

abstract：:Mantle plumes are thought to play a key role in transferring heat from the core-mantle boundary to the lithosphere, where it can significantly influence plate tectonics. On impinging on the lithosphere at spreading ridges or in intra-plate settings, mantle plumes may generate hotspots, large igneous provinces and henc...

journal_title：Nature communications

authors： Chang SJ,Ferreira AM,Faccenda M

更新日期：2016-02-29 00:00:00

abstract：:Saccharomyces cerevisiae is a Crabtree-positive eukaryal model organism. It is believed that the Crabtree effect has evolved as a competition mechanism by allowing for rapid growth and production of ethanol at aerobic glucose excess conditions. This inherent property of yeast metabolism and the multiple mechanisms und...

journal_title：Nature communications

authors： Dai Z,Huang M,Chen Y,Siewers V,Nielsen J

更新日期：2018-08-03 00:00:00

abstract：:The transdifferentiation of pancreatic acinar cells to a ductal phenotype (acinar-to-ductal metaplasia, ADM) occurs after injury or inflammation of the pancreas and is a reversible process. However, in the presence of activating Kras mutations or persistent epidermal growth factor receptor (EGF-R) signalling, cells th...

journal_title：Nature communications

authors： Liou GY,Döppler H,Braun UB,Panayiotou R,Scotti Buzhardt M,Radisky DC,Crawford HC,Fields AP,Murray NR,Wang QJ,Leitges M,Storz P

更新日期：2015-02-20 00:00:00

abstract：:A variety of flexible and stretchable electronics have been reported for use in flexible electronic devices or biomedical applications. The practical and wider application of such flexible electronics has been limited because commercial electronic components are difficult to be directly integrated into flexible stretc...

journal_title：Nature communications

authors： Jeong GS,Baek DH,Jung HC,Song JH,Moon JH,Hong SW,Kim IY,Lee SH

更新日期：2012-01-01 00:00:00

abstract：:The original version of this Article omitted the following from the Acknowledgements:"Satish Patil thanks Department of Science and Technology, New Delhi, India for a Swarnajayanti fellowship."This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Roy P,Jha A,Yasarapudi VB,Ram T,Puttaraju B,Patil S,Dasgupta J

更新日期：2018-01-03 00:00:00

abstract：:Multipotent mesenchymal stromal cells (MSCs) are required for skeletal formation, maintenance, and repair throughout life; however, current models posit that postnatally arising long-lived adult MSCs replace transient embryonic progenitor populations. We previously reported exclusive expression and function of the emb...

journal_title：Nature communications

authors： Pineault KM,Song JY,Kozloff KM,Lucas D,Wellik DM

更新日期：2019-07-18 00:00:00

abstract：:Characterizing the long-term nanometer-scale interactions between lysosomes and mitochondria in live cells is essential for understanding their functions but remains challenging due to limitations of the existing fluorescent probes. Here, we develop cell-permeable organic fluorescent probes for lysosomes with excellen...

journal_title：Nature communications

authors： Han Y,Li M,Qiu F,Zhang M,Zhang YH

更新日期：2017-11-03 00:00:00

abstract：:The functional role of adult neurogenesis in the hippocampus remains the subject of intense speculation. One recent hypothesis is that adult-born neurons contribute to the endocrine and behavioural outputs of the stress response. Here we show a genetic model system to ablate neurogenesis by inducibly deleting Tbr2 gen...

journal_title：Nature communications

authors： Tsai CY,Tsai CY,Arnold SJ,Huang GJ

更新日期：2015-09-29 00:00:00

abstract：:The original version of this Article contained errors in Figs. 1a, 2a, 3a, and 4b, in which the units on the scale bars incorrectly read 'µm' rather than the correct 'nm.' This has been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Babakhanova G,Turiv T,Guo Y,Hendrikx M,Wei QH,Schenning APHJ,Broer DJ,Lavrentovich OD

更新日期：2018-03-14 00:00:00

abstract：:Seismic tomography provides unique constraints on the morphology, the deformation, and (indirectly) the rheology of subducting slabs. We use teleseismic double-difference P-wave tomography to image with unprecedented clarity the structural complexity of the Izu-Bonin slab. We resolve a tear in the slab in the mantle t...

journal_title：Nature communications

authors： Zhang H,Wang F,Myhill R,Guo H

更新日期：2019-03-21 00:00:00

abstract：:A universally accepted explanation for why liquids sometimes vitrify rather than crystallize remains hotly pursued, despite the ubiquity of glass in our everyday lives, the utilization of the glass transition in innumerable modern technologies, and nearly a century of theoretical and experimental investigation. Among ...

journal_title：Nature communications

authors： Teich EG,van Anders G,Glotzer SC

更新日期：2019-01-08 00:00:00

abstract：:Oceanic mesoscale eddies contribute important horizontal heat and salt transports on a global scale. Here we show that eddy transports are mainly due to individual eddy movements. Theoretical and observational analyses indicate that cyclonic and anticyclonic eddies move westwards, and they also move polewards and equa...

journal_title：Nature communications

authors： Dong C,McWilliams JC,Liu Y,Chen D

更新日期：2014-01-01 00:00:00

abstract：:Quantum states induced by single-atomic impurities are at the frontier of physics and material science. While such states have been reported in high-temperature superconductors and dilute magnetic semiconductors, they are unexplored in topological magnets which can feature spin-orbit tunability. Here we use spin-polar...

journal_title：Nature communications

authors： Yin JX,Shumiya N,Jiang Y,Zhou H,Macam G,Sura HOM,Zhang SS,Cheng ZJ,Guguchia Z,Li Y,Wang Q,Litskevich M,Belopolski I,Yang XP,Cochran TA,Chang G,Zhang Q,Huang ZQ,Chuang FC,Lin H,Lei H,Andersen BM,Wang Z,Jia S

更新日期：2020-09-04 00:00:00

abstract：:Post-transcriptional regulation of cellular mRNA is essential for protein synthesis. Here we describe the importance of mRNA translational repression and mRNA subcellular location for protein expression during B lymphocyte activation and the DNA damage response. Cytoplasmic RNA granules are formed upon cell activation...

journal_title：Nature communications

authors： Díaz-Muñoz MD,Kiselev VY,Le Novère N,Curk T,Ule J,Turner M

更新日期：2017-09-13 00:00:00

abstract：:The amniote middle ear is a classical example of the evolutionary novelty. Although paleontological evidence supports the view that mammals and diapsids (modern reptiles and birds) independently acquired the middle ear after divergence from their common ancestor, the developmental bases of these transformations remain...

journal_title：Nature communications

authors： Kitazawa T,Takechi M,Hirasawa T,Adachi N,Narboux-Nême N,Kume H,Maeda K,Hirai T,Miyagawa-Tomita S,Kurihara Y,Hitomi J,Levi G,Kuratani S,Kurihara H

更新日期：2015-04-22 00:00:00

abstract：:When two-dimensional crystals are brought into close proximity, their interaction results in reconstruction of electronic spectrum and crystal structure. Such reconstruction strongly depends on the twist angle between the crystals, which has received growing attention due to interesting electronic and optical properti...

journal_title：Nature communications

authors： Woods CR,Ares P,Nevison-Andrews H,Holwill MJ,Fabregas R,Guinea F,Geim AK,Novoselov KS,Walet NR,Fumagalli L

更新日期：2021-01-12 00:00:00