Abstract：
:Feynman once asked physicists to build better electron microscopes to be able to watch biology at work. While electron microscopes can now provide atomic resolution, electron beam induced specimen damage precludes high resolution imaging of sensitive materials, such as single proteins or polymers. Here, we use simulations to show that an electron microscope based on a multi-pass measurement protocol enables imaging of single proteins, without averaging structures over multiple images. While we demonstrate the method for particular imaging targets, the approach is broadly applicable and is expected to improve resolution and sensitivity for a range of electron microscopy imaging modalities, including, for example, scanning and spectroscopic techniques. The approach implements a quantum mechanically optimal strategy which under idealized conditions can be considered interaction-free.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Juffmann T,Koppell SA,Klopfer BB,Ophus C,Glaeser RM,Kasevich MAdoi
10.1038/s41598-017-01841-xsubject
Has Abstractpub_date
2017-05-10 00:00:00pages
1699issue
1issn
2045-2322pii
10.1038/s41598-017-01841-xjournal_volume
7pub_type
杂志文章abstract：:Recent studies have shown that the representation of an item in visual working memory (VWM) can bias the deployment of attention to stimuli in the visual scene possessing the same features. When multiple item representations are simultaneously held in VWM, whether these representations, especially those held in a non-...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32144-4
更新日期：2018-09-17 00:00:00
abstract：:Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and platelet count (PC) were shown to be prognostic in several solid malignancies. We analysed 603 R0 resected patients to assess whether NLR, PLR and PC correlate with other well-known prognostic factors and survival of patients with colorectal ...
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1038/srep37457
更新日期：2016-11-24 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
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更新日期：2020-09-11 00:00:00
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journal_title：Scientific reports
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更新日期：2016-02-23 00:00:00
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pub_type： 杂志文章
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