Performance of the LACE index to identify elderly patients at high risk for hospital readmission in Singapore.


:Unplanned readmissions may be avoided by accurate risk prediction and appropriate resources could be allocated to high risk patients. The Length of stay, Acuity of admission, Charlson comorbidity index, Emergency department visits in past six months (LACE) index was developed to predict hospital readmissions in Canada. In this study, we assessed the performance of the LACE index in a Singaporean cohort by identifying elderly patients at high risk of 30-day readmissions. We further investigated the use of additional risk factors in improving readmission prediction performance.Data were extracted from the hospital's electronic health records (EHR) for all elderly patients ≥ 65 years, with alive-discharge episodes from Singapore General Hospital in 2014. In addition to LACE, we also collected patients' data during the index admission, including demographics, medical history, laboratory results, and previous medical utilization.Among the 17,006 patients analyzed, 2051 or 12.1% of them were observed 30-day readmissions. The final predictive model was better than the LACE index in terms of discriminative ability; c-statistic of LACE index and final logistic regression model was 0.595 and 0.628, respectively.The LACE index had poor discriminative ability in identifying elderly patients at high risk of 30-day readmission, even if it was augmented with additional risk factors. Further studies should be conducted to discover additional factors that may enable more accurate and timely identification of patients at elevated risk of readmissions, so that necessary preventive actions can be taken.


Medicine (Baltimore)




Low LL,Liu N,Ong MEH,Ng EY,Ho AFW,Thumboo J,Lee KH




Has Abstract


2017-05-01 00:00:00
















  • Chronic postsurgical pain and neuropathic symptoms after abdominal hysterectomy: A silent epidemic.

    abstract::Chronic postsurgical pain (CPSP) is an important clinic problem. It is assessed that prevalence of chronic pain extends to 30% but it is contended that there are various risk factors. We aimed to evaluate the prevalence of chronic pain after hysterectomy, risk factors of chronicity, neuropathic features of pain, and s...


    pub_type: 杂志文章


    authors: Beyaz SG,Özocak H,Ergönenç T,Palabıyık O,Tuna AT,Kaya B,Erkorkmaz Ü,Akdemir N

    更新日期:2016-08-01 00:00:00

  • Primary pulmonary hepatoid adenocarcinoma: A case report and review of the literature.

    abstract:RATIONALE:Hepatoid adenocarcinoma of lung (HAL) is a rare malignant tumor, which can be defined as a primary alpha-fetoprotein (AFP)-producing lung carcinoma. The majority of hepatoid adenocarcinoma (HAC) expressed AFP in tumor cells, but AFP expression is not required for its diagnosis according to the modified diagno...


    pub_type: 杂志文章,评审


    authors: Yang K,Jiang H,Li Q

    更新日期:2019-04-01 00:00:00

  • Predictive validity of the ACS-NSQIP surgical risk calculator in geriatric patients undergoing lumbar surgery.

    abstract::The risk calculator of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) has been shown to be useful in predicting postoperative complications. In this study, we aimed to evaluate the predictive value of the ACS-NSQIP calculator in geriatric patients undergoing lumbar surgery.A...


    pub_type: 杂志文章


    authors: Wang X,Hu Y,Zhao B,Su Y

    更新日期:2017-10-01 00:00:00

  • Relation Between Hepatitis C Virus Exposure and Risk of Osteoporosis: A Nationwide Population-Based Study.

    abstract::The effect of hepatitis C virus (HCV) exposure on bone mineral density without advanced liver disease remains debated. Thus, we assessed the relation between HCV exposure and the risk of osteoporosis.From 2000 to 2011, patients aged >20 years with HCV exposure were identified from the Longitudinal Health Insurance Dat...


    pub_type: 杂志文章


    authors: Chen CH,Lin CL,Kao CH

    更新日期:2015-11-01 00:00:00

  • Does Breast Magnetic Resonance Imaging Combined With Conventional Imaging Modalities Decrease the Rates of Surgical Margin Involvement and Reoperation?: A Case-Control Comparative Analysis.

    abstract::The objective of this study was to assess whether preoperative breast magnetic resonance imaging (MRI) combined with conventional breast imaging techniques decreases the rates of margin involvement and reexcision.Data on patients who underwent surgery for primary operable breast cancer were obtained from the Changhua ...


    pub_type: 杂志文章


    authors: Lai HW,Chen CJ,Lin YJ,Chen SL,Wu HK,Wu YT,Kuo SJ,Chen ST,Chen DR

    更新日期:2016-05-01 00:00:00

  • Surgical treatment of pyloric stenosis caused by glyphosate poisoning: A case report.

    abstract:RATIONALE:Oral ingestion of glyphosate can induce gastrointestinal symptoms such as vomiting, abdominal pain, and hematochezia. Timely and effective treatment of pyloric stenosis caused by glyphosate poisoning is important. PATIENT CONCERNS:The patient had a poor appetite, accompanied by nausea and vomiting of a small...


    pub_type: 杂志文章


    authors: Luo W,Lu T,Li F,Qian C,Zhang L,Sun M,Xu Z,Jia Y

    更新日期:2019-07-01 00:00:00

  • High internal radiation exposure associated with low socio-economic status six years after the Fukushima nuclear disaster: A case report.

    abstract:RATIONALE:Managing the health of vulnerable groups is an important component of health care. Given the long-term burden of radiation-release incidents among those exposed, managing the health of vulnerable groups following a nuclear disaster is very important. However, there is limited information available concerning ...


    pub_type: 杂志文章


    authors: Sawano T,Kambe T,Seno Y,Konoe R,Nishikawa Y,Ozaki A,Shimada Y,Morita T,Saito H,Tsubokura M

    更新日期:2019-11-01 00:00:00

  • Adjuvant endocrine therapy alone in patients with node-positive, luminal A type breast cancer.

    abstract::Luminal A breast cancer has a much better prognosis than other subtypes, with a low risk of local or regional recurrence. However, there is controversy around under- versus overtreatment with regard to adjuvant treatment of node-positive, luminal A breast cancer. The purpose of this study was to identify whether adjuv...


    pub_type: 杂志文章


    authors: Park S,Lee SK,Paik HJ,Ryu JM,Kim I,Bae SY,Yu J,Kim SW,Lee JE,Nam SJ

    更新日期:2017-06-01 00:00:00

  • Using bioinformatics approach identifies key genes and pathways in idiopathic pulmonary fibrosis.

    abstract::Idiopathic pulmonary fibrosis is a chronic and irreversible respiratory disease with a high incidence worldwide and no specific treatment. Currently, the etiology and pathogenesis of this disease remain largely unknown. In main purpose of this study, bioinformatics analysis was used to uncover key genes and pathways r...


    pub_type: 杂志文章


    authors: Xu Z,Mo L,Feng X,Huang M,Li L

    更新日期:2020-09-04 00:00:00

  • Effects of mitochondrial ATP-sensitive potassium channel activation (nicorandil) in patients with angina pectoris undergoing elective percutaneous coronary interventions: A meta-analysis of randomized controlled trials.

    abstract:AIMS:Nicorandil, which is a mitochondrial ATP-sensitive potassium channel opener, is believed to improve perioperative myocardial injury (PMI) in patients undergoing percutaneous coronary intervention (PCI), but recent studies have shown that nicorandil treatment did not improve functional and clinical outcomes in pati...


    pub_type: 杂志文章,meta分析,评审


    authors: Zhu H,Xu X,Fang X,Zheng J,Chen T,Huang J

    更新日期:2019-01-01 00:00:00

  • The effect of intra-articular stimulation by pulsed radiofrequency on chronic sacroiliac joint pain refractory to intra-articular corticosteroid injection: A retrospective study.

    abstract::We investigated the degree of pain reduction following intra-articular (IA) pulsed radiofrequency (PRF) stimulation of the sacroiliac joint (SIJ) in patients with chronic SIJ pain that had not responded to IA corticosteroid injection. Twenty patients were recruited. Clinical outcomes after applying PRF stimulation of ...


    pub_type: 杂志文章


    authors: Chang MC,Ahn SH

    更新日期:2017-06-01 00:00:00

  • Treatment of lateral epicondylitis with acupuncture and glucocorticoid: A retrospective cohort study.

    abstract::Lateral epicondylitis (LE) is a common musculoskeletal disorder for which an effective treatment strategy remains unknown. The goal of this study is to examine whether acupuncture is more effective than injection of glucocorticoid in adults with LE.Adults with LE received either acupuncture or injection of glucocortic...


    pub_type: 杂志文章


    authors: Peng Z,Zhang M,Li Y,Feng Z

    更新日期:2020-02-01 00:00:00

  • Cardiac malignant peripheral nerve sheath tumor on computed tomography and magnetic resonance imaging: A case report.

    abstract:RATIONALE:Malignant peripheral nerve sheath tumor (MPNST) is a very rare sarcoma of the heart, and few cases have been reported. Herein, we retrospectively reviewed clinical manifestations, imaging features and management of our patient and other reported cases. PATIENT CONCERNS:A 32-year-old woman was referred to the...


    pub_type: 杂志文章


    authors: Li S,Qiu Y,Yu J,Liang C,Peng L

    更新日期:2019-11-01 00:00:00

  • A comparative study of four Bowie-Dick test under the condition of pressure steam sterilizer simulating gas leakage.

    abstract::We aimed to understand the evaluation of different Bowie-Dick test (B-D test) on the performance of pressure steam sterilization equipment in the case of simulated gas leakage, and we selected a pulsating vacuum steam sterilizer to set 4 different gas leakage levels: 1.1, 1.3, 1.5, and 1.7 mbar/min during the B-D test...


    pub_type: 杂志文章


    authors: Yu X,Zhang Q,Deng X,Liang J,Hao S,Chen J,Du H

    更新日期:2020-12-11 00:00:00

  • Characteristics of lymph node metastasis in resected adenosquamous lung cancer.

    abstract::The aim of this study was to retrospectively analyze the clinical data of resected adenosquamous lung cancer (ASLC) and to explore the influencing factors and clinicopathological characteristics of the metastasis lymph nodes. A total of 1156 consecutive patients with surgically resected lung cancer from January 2009 t...


    pub_type: 杂志文章


    authors: Kong M,Jin J,Cai X,Shen J,Ma D,Ye M,Zhu C,Freedman S,Walters K,Xu X,Chen B

    更新日期:2017-12-01 00:00:00

  • Extremity fractures in patients presenting with traumatic spinal fractures and spinal cord injury.

    abstract::Clinical features of extremity fractures (EFs) in patients presenting with traumatic spinal fractures (TSFs) and spinal cord injury (SCI) have not been investigated. To investigate the clinical features and risk factors for EFs in patients presenting with TSFs and SCI.Data from 1392 patients presenting with TSFs and S...


    pub_type: 杂志文章,多中心研究


    authors: Wang H,Wu D,Xu W,Zhu Y,Liu H,Li C,Liu J,Ou L,Xiang L

    更新日期:2020-01-01 00:00:00

  • A High Circulating Tumor Cell Count in Portal Vein Predicts Liver Metastasis From Periampullary or Pancreatic Cancer: A High Portal Venous CTC Count Predicts Liver Metastases.

    abstract::Circulating tumor cells (CTCs) released from a periampullary or pancreatic cancer can be more frequently detected in the portal than the systemic circulation and potentially can be used to identify patients with liver micrometastases. Aims of this study is to determine if CTCs count in portal venous blood of patients ...


    pub_type: 杂志文章


    authors: Tien YW,Kuo HC,Ho BI,Chang MC,Chang YT,Cheng MF,Chen HL,Liang TY,Wang CF,Huang CY,Shew JY,Chang YC,Lee EY,Lee WH

    更新日期:2016-04-01 00:00:00

  • Hypertension and selected indicators of health assessment in a population of 19-year-old men subject to military qualifications.

    abstract::Assessment the prevalence of hypertension and its relation to selected indicators of health status and performance, including classification of BMI, obesity classifications, and body structure in a large test group of 19-year-old men.The study was observational-retrospective, and included a group of 17,282 men, aged 1...


    pub_type: 杂志文章


    authors: Chmiel Z,Żal M,Więch P,Bazaliński D,Sałacińska I,Bartusik-Aebisher D,Binkowska-Bury M

    更新日期:2020-05-29 00:00:00

  • The association between normal-range admission potassium levels in Israeli patients with acute coronary syndrome and early and late outcomes.

    abstract::Abnormal serum potassium levels are associated with an increased risk of ventricular arrhythmias and mortality in patients with acute myocardial infarction (AMI). The aim of the present study was to evaluate whether different levels of serum potassium, within the normal range, are associated with worse outcomes. The p...


    pub_type: 杂志文章,多中心研究


    authors: Shlomai G,Berkovitch A,Pinchevski-Kadir S,Bornstein G,Leibowitz A,Goldenberg I,Grossman E

    更新日期:2016-06-01 00:00:00

  • Determination of the optimal target level of proteinuria in the management of patients with glomerular diseases by using different definitions of proteinuria.

    abstract::Proteinuria is a major determinant of adverse renal outcome, and its reduction slows renal progression in glomerular diseases. However, the optimal target of proteinuria in glomerular diseases is unclear, and discrepancies in the definition of proteinuria produce ambiguous findings. Here we investigated the optimal ta...


    pub_type: 杂志文章


    authors: Kee YK,Yoon CY,Kim SJ,Moon SJ,Kim CH,Park JT,Lim BJ,Chang TI,Kang EW,Kie JH,Yoo TH,Jeong HJ,Kang SW,Han SH

    更新日期:2017-11-01 00:00:00

  • A clinical evaluation denture adhesives used by patients with xerostomia.

    abstract::The purpose of study was to analyze the participants' opinions concerning the effectiveness of 6 denture adhesives (DA). The study group included 60 participants. Criteria for selecting the patients were as follows: reduced retention and stabilization of maxillary complete dentures and xerostomia. These features were ...


    pub_type: 杂志文章


    authors: Bogucki ZA,Napadlek P,Dabrowa T

    更新日期:2015-02-01 00:00:00

  • Associated risk factors for psychological distress in patients with gastric epithelial neoplasm undergoing endoscopic submucosal dissection.

    abstract::This study aimed to evaluate the psychological distress and associated risk factors for distress among patients with gastric epithelial neoplasm undergoing endoscopic submucosal dissection (ESD).A total of 91 patients treated with ESD for gastric epithelial neoplasm between May 2015 and June 2016 were prospectively en...


    pub_type: 杂志文章


    authors: Lee S,Oh ST,Lee H,Lee JS,Pak H,Choi WJ,Jeon HH

    更新日期:2018-12-01 00:00:00

  • Pediatric minimally invasive surgery for malignant abdominal tumor: Single center experience.

    abstract::This study examined the safety and usefulness of minimally invasive surgery (MIS) for malignant abdominal tumors in pediatric patients and analyzed the factors affecting the resection margin, operative time, and hospital stay of neuroblastoma (NBL) patients.We retrospectively reviewed data of pediatric patients who un...


    pub_type: 杂志文章


    authors: Yang HB,Kim HY,Jung SE,Choi YH,Lee JW

    更新日期:2019-08-01 00:00:00

  • Sudden seizure during cesarean section: A case report.

    abstract:RATIONALE:A first seizure can range from a fleeting subjective experience or a twitch (myoclonic jerk) through to a tonic-clonic convulsion. A first seizure occurred in a parturient during cesarean section is very rare. We describe the case of a parturient who suffered seizure when the fetus was delivered. PATIENT CON...


    pub_type: 杂志文章


    authors: Zhou W,Zhu Q

    更新日期:2018-12-01 00:00:00

  • Acupuncture therapy strategy options in postoperative management after laparoscopic cholecystectomy: A protocol for systematic review and Bayesian meta-analysis.

    abstract:BACKGROUND:Laparoscopic cholecystectomy (LC) is a common surgery accompanied by some unpleasant adverse effects. Clinical trials indicated that acupuncture therapy may help reduce complications in LC. However, no systematic reviews have been conducted on the topic. Therefore, we will evaluate the current evidence and p...


    pub_type: 杂志文章,meta分析


    authors: Zhao DQ,Qian GY,Jin J,Yao YP,Bian XM,Zhang WP

    更新日期:2021-01-08 00:00:00

  • Improving functional outcome and quality of life for patients with metastatic lesion of acetabulum undergoing cement augmentation.

    abstract::There is an increased enthusiasm in treating osteolytic metastatic acetabulum via injecting polymethyl-methacrylate (PMMA) as a bone filler to provide pain relief and potential structural support. The aim of this respective study is to determine the function and quality of life improvement after cement acetabuloplasty...


    pub_type: 杂志文章


    authors: Yan T,Zhao Z,Tang X,Guo W,Yang R,Tang S,Dong S

    更新日期:2019-09-01 00:00:00

  • CXC motif chemokine receptor 4 gene polymorphism and cancer risk.

    abstract:BACKGROUND:Previous epidemiological studies have reported the relationship between CXC motif chemokine receptor 4 (CXCR4) synonymous polymorphism (rs2228014), and risk of cancer, but the results remained conflicting and controversial. Therefore, this study was devised to evaluate the genetic effects of the rs2228014 po...


    pub_type: 杂志文章,meta分析,评审


    authors: Wu Y,Zhang C,Xu W,Zhang J,Zheng Y,Lu Z,Liu D,Jiang K

    更新日期:2016-12-01 00:00:00

  • Successful Treatment of Scrub Typhus-Associated Hemophagocytic Lymphohistiocytosis With Chloramphenicol: Report of 3 Pediatric Cases and Literature Review.

    abstract::Scrub typhus is caused by Orientia tsutsugamushi. Any delay in diagnosis can result in delayed treatment and severe complications, including secondary hemophagocytic lymphohistiocytosis, which is rare but potentially fatal.In this paper, the authors present 3 cases of secondary hemophagocytic lymphohistiocytosis assoc...


    pub_type: 杂志文章,评审


    authors: Zhou YH,Xia FQ,Van Poucke S,Zheng MH

    更新日期:2016-02-01 00:00:00

  • Efficacy of herbal medicine (Gegen Qinlian Decoction) on ulcerative colitis: A systematic review of randomized controlled trials.

    abstract:BACKGROUND:This systematic review aims to evaluate the efficacy of Gegen Qinlian Decoction (GQD) for ulcerative colitis (UC). METHODS:PubMed, EMBASE, Springer LINK, Cochrane Library, the China National Knowledge Infrastructure, Chongqing Weipu Database for Chinese Technical Periodicals, Wan-fang Database, and Chinese ...


    pub_type: 杂志文章,meta分析


    authors: Fan Y,Yi W,Huang H,Mei Z,Feng Z

    更新日期:2019-12-01 00:00:00

  • Rapid and Complete Remission of Metastatic Adrenocortical Carcinoma Persisting 10 Years After Treatment With Mitotane Monotherapy: Case Report and Review of the Literature.

    abstract::Mitotane has been used for more than 5 decades as therapy for adrenocortical carcinoma (ACC). However its mechanism of action and the extent of tumor response remain incompletely understood. To date no cases of rapid and complete remission of metastatic ACC with mitotane monotherapy has been reported. A 52-year-old Fr...


    pub_type: 杂志文章


    authors: El Ghorayeb N,Rondeau G,Latour M,Cohade C,Olney H,Lacroix A,Perrotte P,Sabourin A,Mazzuco TL,Bourdeau I

    更新日期:2016-03-01 00:00:00