Abstract:
:Unplanned readmissions may be avoided by accurate risk prediction and appropriate resources could be allocated to high risk patients. The Length of stay, Acuity of admission, Charlson comorbidity index, Emergency department visits in past six months (LACE) index was developed to predict hospital readmissions in Canada. In this study, we assessed the performance of the LACE index in a Singaporean cohort by identifying elderly patients at high risk of 30-day readmissions. We further investigated the use of additional risk factors in improving readmission prediction performance.Data were extracted from the hospital's electronic health records (EHR) for all elderly patients ≥ 65 years, with alive-discharge episodes from Singapore General Hospital in 2014. In addition to LACE, we also collected patients' data during the index admission, including demographics, medical history, laboratory results, and previous medical utilization.Among the 17,006 patients analyzed, 2051 or 12.1% of them were observed 30-day readmissions. The final predictive model was better than the LACE index in terms of discriminative ability; c-statistic of LACE index and final logistic regression model was 0.595 and 0.628, respectively.The LACE index had poor discriminative ability in identifying elderly patients at high risk of 30-day readmission, even if it was augmented with additional risk factors. Further studies should be conducted to discover additional factors that may enable more accurate and timely identification of patients at elevated risk of readmissions, so that necessary preventive actions can be taken.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Low LL,Liu N,Ong MEH,Ng EY,Ho AFW,Thumboo J,Lee KHdoi
10.1097/MD.0000000000006728subject
Has Abstractpub_date
2017-05-01 00:00:00pages
e6728issue
19eissn
0025-7974issn
1536-5964pii
00005792-201705120-00017journal_volume
96pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Intramuscular hemangiomas are rare benign vascular neoplasms, merely accounting for 0.8% of all hemangiomas. Moreover, there are few case reports of intramuscular hemangiomas in the upper extremities. PATIENT CONCERNS:A 24-year-old male patient presented with a 5-year history of intermittent pain of the righ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014343
更新日期:2019-02-01 00:00:00
abstract::We describe the clinical characteristics and actuarial survival of a consecutive cohort of 41 patients with rheumatoid arthritis and clinical pericarditis who were seen at the Mayo Clinic between 1970 and 1987 and followed up until death or through 1987. The survivors were followed up for a median of 5.1 years. Approx...
journal_title:Medicine
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::Detailed characterizations of ocular biometrics and parameters of aqueous humor dynamics are lacking in primary angle closure suspect (PACS) patients. This study aims to characterize these parameters and compare them with age-matched healthy volunteers.Elderly healthy volunteers (60.6 ± 7.2 years of age, mean ± SD, n ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006096
更新日期:2017-02-01 00:00:00
abstract::To examine whether scrotoscopy could be used to diagnose testicular rupture (TR) with accuracy.This retrospective study included all patients receiving scrotoscopy followed by immediate open exploration (OE) for suspected TR at two Chinese tertiary care centers between March 2014 and March 2018.Fifteen patients suspec...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017389
更新日期:2019-10-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002241.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000479433.86506.88
更新日期:2016-01-08 00:00:00
abstract:BACKGROUND AND AIM:Although abdominal pain is a common adverse event related to endoscopic submucosal dissection (ESD), it can be sometimes underestimated by endoscopists. There are some endoscopic interventions available for the prevention of post-ESD pain, but their efficacy has not been established. We investigated ...
journal_title:Medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/MD.0000000000015360
更新日期:2019-04-01 00:00:00
abstract::To summary the impact of off-pump coronary artery bypass grafting (CABG) only on patients with moderate ischemic mitral regurgitation and survival.We retrospectively analyzed 109 patients with coronary artery disease (CAD) complicated by moderate mitral regurgitation, from January, 2008 to December, 2014, in the Depar...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014969
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Apatinib-targeted therapy is considered a promising treatment option for malignancies. This study systematically evaluated the efficacy and safety of the combination of apatinib and S-1 for the treatment of patients with advanced gastric cancer (GC). METHODS:Clinical trials were searched from the PubMed, Co...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013259
更新日期:2018-11-01 00:00:00
abstract::To investigate the efficacy, key technical points, and complication management of the transabdominal preperitoneal (TAPP) approach for incarcerated inguinal hernia repair. Seventy-three patients with incarcerated inguinal hernias underwent TAPP surgery in our department between Jan 2010 and Dec 2015. A retrospective r...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005686
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Our study aimed to screen and explore the expression of inflammatory factors in keloid patients and to investigate how hyperbaric oxygen (HBO) therapy affects the expression levels of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP-1β), platelet-derived growth factor-BB (PDGF-BB), and i...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000019857
更新日期:2020-04-01 00:00:00
abstract::Essential hypertension often requires affected patients to self-manage their condition most of the time. Besides seeking regular medical review of their life-long condition to detect vascular complications, patients have to maintain healthy lifestyles in between physician consultations via diet and physical activity, ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002955
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:The minimally invasive surgery possesses an essential and growing function in treating the calcaneal fractures, but the related literature on this topic is limited. For our study, the main purpose was to compare the early prognosis of a group of the patients with Sanders type II fracture of calcaneus treated...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023813
更新日期:2020-12-18 00:00:00
abstract:BACKGROUND:With the improvement of anesthesia and surgical techniques, supraglottic device with assist ventilation under general anesthesia (GA) combined with nerve block is gradually applied to video-assisted thoracoscopic surgery. However, the safety of assist ventilation has not been fully confirmed, and a large num...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000019240
更新日期:2020-03-01 00:00:00
abstract:RATIONALE:The capsular warning syndrome (CWS) is a rare and special type of transient ischemic attacks (TIAs) syndrome. The pathophysiology of CWS is very complicate, and intracranial atherosclerotic stenosis (ICAS) is rare cause. Moreover, the effective and standard therapy has not yet been established. PATIENT CONCE...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019247
更新日期:2020-02-01 00:00:00
abstract::A significant characteristic of advanced gastric cancer (GC) is immune suppression, which can promote the progression of GC. Interleukin 35 (IL-35) is an immune-suppressing cytokine, and it is generally recognized that this cytokine is secreted by regulatory T (Treg) cells. Recently, studies have found that IL-35 can ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010710
更新日期:2018-05-01 00:00:00
abstract::There is currently a lack of reliable, reproducible, and easily applied methods for assessing changes in liver histology in patients in the gray zone phase of chronic hepatitis B (CHB). Therefore, we aimed to develop a novel predictive scoring system to detect significant liver histological changes in these patients.A...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006465
更新日期:2017-04-01 00:00:00
abstract::Adipokines have many homeostatic roles, including modulation of glucose metabolism, but their role in the pathophysiology of hyperglycemia associated with acute and critical illnesses in general, and acute pancreatitis (AP) in particular, is largely unknown. This study aimed to investigate the relationship between a p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002382
更新日期:2016-02-01 00:00:00
abstract::In this study, we evaluate the efficacy of short-course radiotherapy (SCRT) versus long-course radiotherapy (LCRT) in the treatment of metastatic spinal cord compression (MSCC).PubMed, EMBASE, and Web of Science were searched up to April 2015. Relevant data were extracted based on inclusion and exclusion criteria. Met...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001843
更新日期:2015-10-01 00:00:00
abstract::Acute coronary syndrome (ACS) leads to clinical symptoms such as chest pain, dyspnea, and arrhythmia. The occurrence of ACS is mainly related to the vulnerable plaques in the coronary arteries. MicroRNA-21 (miR-21) is widely expressed in cardiovascular disease and considered as a marker of myocardial infarction, but i...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018049
更新日期:2019-11-01 00:00:00
abstract::We aim to determine the incidence of malignancy after liver transplantation (LT) compared to general population. The records of patients who received LTs at our center from October 1989 and November 2012 were retrospectively reviewed. The standardized incidence ratio (SIR) of cancer in the patients was compared to gen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000310
更新日期:2014-12-01 00:00:00
abstract::We aimed to evaluate the image quality performance of coronary CT angiography (CTA) under the different settings of forward-projected model-based iterative reconstruction solutions (FIRST).Thirty patients undergoing coronary CTA were included. Each image was reconstructed using filtered back projection (FBP), adaptive...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010810
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The critically ill and surgical patients are at significant risk of delirium, which is associated with a high morbidity and mortality. The association between statin use and the incidence of delirium is still controversial. In this article, we will perform a systematic review and meta-analysis of published s...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013679
更新日期:2018-12-01 00:00:00
abstract:RATIONALE:Primary intracranial leiomyosarcoma (LMS) is an extremely rare tumor in the central nervous system (CNS), and usually seen in immunocompromised individuals. Only a few cases of primary intracranial LMS have been documented in the literature and no study focused on their MRI findings. We reported a case of pri...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015269
更新日期:2019-04-01 00:00:00
abstract:INTRODUCTION:Brain perfusion single photon computed tomography (SPECT) is a functional imaging modality and has been widely utilized in evaluation of various kinds of neurological disorders. Easy z-score imaging system (eZIS) is a computer-assisted statistical analysis, based on the comparison with age-classified ethyl...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005416
更新日期:2016-11-01 00:00:00
abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019778
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is the most common cause of motor neuron disease, and effective treatment for ALS is still lacking. Transactive response (TAR) -DNA-binding protein-43 (TDP-43) is aggregated in the neurons of ALS patients. Animal studies shown TDP-43 aggregation can be attenuated by enha...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000020423
更新日期:2020-05-29 00:00:00
abstract:RATIONALE:When patients are intubated and treated with mechanical ventilation, the upper respiratory tract is bypassed by the flow of dry and cold air. To prevent disturbances of airway homeostasis, a heat and moisture exchanger filter (HMEF) has been applied to breathing circuit. PATIENT CONCERNS:A 4-month-old male i...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012158
更新日期:2018-08-01 00:00:00
abstract:INTRODUCTION:Ciliated retroperitoneal foregut cysts are rare, and to obtain a preoperative definitive diagnosis of this condition is relatively difficult. In addition, the exact mechanism and formation of ciliated retroperitoneal foregut cysts remains unknown. CASE PRESENTATION:Here, we report a case of a 47-year-old ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010783
更新日期:2018-05-01 00:00:00
abstract:INTRODUCTION:Hemorrhagic shock and encephalopathy syndrome (HSES) is a type of acute encephalopathy mainly seen in infants. It is a syndrome encompassing an onset of high fever, disturbance of consciousness, convulsion, and shock that rapidly progresses to watery diarrhea and liver and renal dysfunctions. It is extreme...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015012
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead to disability and is often associated with cardiovascular disease, poor quality of life, and mortality. The most common treatment for KOA is non-steroidal anti-inflammatory drug administra...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000019541
更新日期:2020-03-01 00:00:00