Tumor suppressive function of microRNA-192 in acute lymphoblastic leukemia.

abstract：:Non-small-cell lung cancer (NSCLC) with KRAS (Kirsten RAt Sarcoma 2 viral oncogene homolog) mutation has become a clinical challenge in cancer treatment as KRAS-mutant tumors are often resistant to conventional anti-tumor therapies. Activated CDC42-associated kinase 1 (ACK1), an activator of protein kinase B (AKT), is...

journal_title：Bosnian journal of basic medical sciences

authors： Yu X,Liu J,Qiu H,Hao H,Zhu J,Peng S

更新日期：2020-06-01 00:00:00

abstract：:The aim of the study was to verify the presence of mutated tumor suppresser gene p53 in intestinal mucosa with histologically confirmed premalignant lesions and gastric carcinoma, and assess its prognostic value. The paper presents prospective study that included 50 patients with gastric adeno-carcinoma of intestinal ...

journal_title：Bosnian journal of basic medical sciences

authors： Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković S

更新日期：2007-02-01 00:00:00

abstract：:Ebselen is an organoselenium compound which has strong antioxidant and anti-inflammatory effects. We investigated the neuroprotective role of ebselen pretreatment in rats with experimental sciatic nerve ischemia-reperfusion (I/R) injury. Adult male Sprague Dawley rats were divided into four groups (N = 7 in each group...

journal_title：Bosnian journal of basic medical sciences

authors： Ozyigit F,Kucuk A,Akcer S,Tosun M,Kocak FE,Kocak C,Kocak A,Metineren H,Genc O

更新日期：2015-08-26 00:00:00

abstract：:Large scale genetic association meta-analyses showed that neurocan (NCAN) gene polymorphism rs1064395 is susceptibility locus for bipolar disorder. These studies also included patients with bipolar disorder originated from Bosnia and Herzegovina. Followed by theory of shared genetic elements between bipolar disorder a...

journal_title：Bosnian journal of basic medical sciences

authors： Oruč L,Kapur-Pojskić L,Ramić J,Pojskić N,Bajrović K

更新日期：2012-11-01 00:00:00

abstract：:Bone marrow aspiration (BMA) through the iliac crest is potentially unsafe due to the vicinity of neurovascular structures in the greater sciatic notch. Our objective was to investigate the safety of a recently described BMA technique, specifically a trajectory from the posterior superior iliac spine (PSIS) to the ant...

journal_title：Bosnian journal of basic medical sciences

authors： D'Souza RS,Li L,Leng S,Hunt C,Law L,Muir C,Eldrige J,Bydon M,Chi M,Shapiro S,Mauck WD,Qu W

更新日期：2020-05-11 00:00:00

abstract：:The aim of this study is to compare two major urological procedures in terms of patient exposure to radiation. We evaluated 175 patients, that were subjected to retrograde ureteroscopy (URS) and extracorporeal shock waves lithotripsy (ESWL) for lumbar or pelvic ureteral lithiasis, at two urological departments. The C-...

journal_title：Bosnian journal of basic medical sciences

authors： Pricop C,Maier A,Negru D,Malau O,Orsolya M,Radavoi D,Serban DR

更新日期：2014-10-18 00:00:00

abstract：:C-reactive protein (CRP) is an important predictor of cardiovascular events and plays a role in vascular inflammation and vessel damage. The aim of this study was to investigate the effect of pentameric CRP (pCRP) and monomeric CRP (mCRP) on the production of atherosclerosis-re-lated factors in cultured human coronary...

journal_title：Bosnian journal of basic medical sciences

authors： Zhang Y,Cao H

更新日期：2020-11-02 00:00:00

abstract：:This is the first study performed in population from Bosnia & Herzegovina (BH), in which we analysed a significance of genetic variations in drug-metabolising enzyme, cytochrome P450 (CYP), in pathogenesis of Type 2 diabetes. We have determined allele frequencies for CYP2C9*2, CYP2C19*2, and CYP2D6*4 in diabetic patie...

journal_title：Bosnian journal of basic medical sciences

authors： Semiz S,Dujic T,Ostanek B,Prnjavorac B,Bego T,Malenica M,Marc J,Causevic A

更新日期：2010-11-01 00:00:00

abstract：:Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common condition; when conservative approaches are not effective, surgical techniques aimed at reducing the airway obstruction effect are used. This retrospective study aimed at comparing the functional outcomes in patients with OSAHS undergoing uvulopalatopharyng...

journal_title：Bosnian journal of basic medical sciences

authors： Minni A,Cialente F,Ralli M,Colizza A,Lai Q,Placentino A,Franco M,Rossetti V,De Vincentiis M

更新日期：2020-04-27 00:00:00

abstract：:MicroRNAs (miRNAs) have an important role in the regulation of tumor development and metastasis. In this study, we investigated the clinical and prognostic value as well as biological function of miR-466 in colorectal cancer (CRC). Tumor and adjacent healthy tissues were obtained from 100 patients diagnosed with CRC. ...

journal_title：Bosnian journal of basic medical sciences

authors： Tong F,Ying Y,Pan H,Zhao W,Li H,Zhan X

更新日期：2018-08-01 00:00:00

abstract：:The purpose of this study was to investigate trends in the incidence of upper tract urothelial carcinoma (UTUC) in patients and to establish a reliable and practical nomogram based on significant clinical factors to predict the overall survival (OS) and cancer-specific survival (CSS) of UTUC patients. The Surveillance...

journal_title：Bosnian journal of basic medical sciences

authors： Wu J,Chen S,Wu X,Mao W,Wang Y,Xu B,Zheng D,Chen M

更新日期：2020-12-18 00:00:00

abstract：:Neurological outcome is an important determinant of death in admitted survivors after out-of-hospital cardiac arrest (OHCA). Studies demonstrated several significant pre-hospital predictors of ischemic brain injury (time to resuscitation, time of resuscitation, and cause of OHCA). Our aim was to evaluate the relations...

journal_title：Bosnian journal of basic medical sciences

authors： Marinšek M,Sinkovič A,Šuran D

更新日期：2020-08-03 00:00:00

abstract：:Amorphous forms are, by definition, non-crystalline materials which possess no long-range order. Their structure can be thought of as being similar to that of a frozen liquid with the thermal fluctuations present in a liquid frozen out, leaving only "static" structural disorder. The amorphous solids have always been a...

journal_title：Bosnian journal of basic medical sciences

authors： Vranić E

更新日期：2004-07-01 00:00:00

abstract：:The aim of this trial was to examine the efficacy and safety of antihypertensive fixed combination lisinopril plus hydrochlorothiazide (Lopril H, Bosnalijek dd) in the treatment of essential arterial hypertension. In our trial we included 297 patients, aged 54.65+/-9.6 years, with treated or untreated hypertension and...

journal_title：Bosnian journal of basic medical sciences

authors： Gerc V,Begović B,Vehabović M,Voronkov LG,Vataman E,Musić L,Buksa M,Kusljugić Z,Ilyash MG,Ena LM,Tchelujko VI,Dyaduk AI,Bagrij AE,Andrievskaja SA,Vehabović A,Knezević B,Hima F

更新日期：2007-11-01 00:00:00

abstract：:Growth hormone is essential for body growth but it also modulates metabolic pathways as well as neural, reproductive, immune, cardiovascular, and pulmonary functions. Numerous beneficial effects of growth hormone have led to its expanded therapeutic use in both children and adults. There are several officially approve...

journal_title：Bosnian journal of basic medical sciences

authors： Hadzović A,Nakas-Ićindić E,Kucukalić-Selimović E,Salaka AU

更新日期：2004-10-01 00:00:00

abstract：:Recent literature suggests that alterations in both neural and structural components of the neuromuscular system are major determinants of knee extensor muscle weakness after total knee arthroplasty (TKA). Therefore, the goal of this study was to investigate the maximal voluntary strength (MVS), voluntary muscle activ...

journal_title：Bosnian journal of basic medical sciences

authors： Paravlic AH,Kovač S,Pisot R,Marusic U

更新日期：2020-02-05 00:00:00

abstract：:Neonatal BCG vaccination reduces the risk of tuberculosis and provides protection higher than 80% against the development of meningeal and miliary tuberculosis in newborns. Tuberculosis meningitis remains a major problem and also an important cause of death in some countries. In countries with high and moderate incide...

journal_title：Bosnian journal of basic medical sciences

authors： Puvacić S,Dizdarević J,Santić Z,Mulaomerović M

更新日期：2004-02-01 00:00:00

abstract：:We investigated serum concentration of C-reactive protein (CRP) and measures of adiposity in 30 patients with type 2 diabetes mellitus (15 male, 15 female) and 30 age and sex-matched apparently healthy subjects. CRP concentration was determined by laser nephelometry (BN II Analyzer) and CardioPhase high-sensitivity CR...

journal_title：Bosnian journal of basic medical sciences

authors： Zaciragić A,Huskić J,Hadzović-Dzuvo A,Valjevac A,Avdagić N,Mulabegović N

更新日期：2007-11-01 00:00:00

abstract：:The objective of our study was to evaluate bladder outlet obstruction number (BOON) in order to predict infravesical obstruction in patients with benign prostatic enlargement (BPE). Two hundred patients with proven BPE from daily urological practice at the Urology Department of the Sarajevo University Clinical Centre ...

journal_title：Bosnian journal of basic medical sciences

authors： Aganovic D,Spahovic H,Prcic A,Hadziosmanovic O

更新日期：2012-08-01 00:00:00

abstract：:Intracerebral hemorrhage is the deadliest, most disabling and least treatable form of stroke despite progression in medical science. The aim of the study was to analyze the frequency, risk factors, localization and 30-day prognosis in patients with intracerebral hemorrhage. We analyzed 352 patients with intracerebral ...

journal_title：Bosnian journal of basic medical sciences

authors： Smajlović D,Salihović D,C Ibrahimagić O,Sinanović O,Vidović M

更新日期：2008-05-01 00:00:00

abstract：:The aim of the study was to ascertain the existence of intestinal metaplasia in gastric mucosa of patients with gastric carcinoma coupled with H. pylori positive chronic atrophic gastritis and possible connection of IM with the development of gastric carcinoma. The paper presents prospective study that included 50 pat...

journal_title：Bosnian journal of basic medical sciences

authors： Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković S

更新日期：2006-11-01 00:00:00

abstract：:Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women. p16/Ki-67 dual immunocytochemical staining can also be used for the detection of oncogenic changes in cervical cells. Our aim was to compare the perform...

journal_title：Bosnian journal of basic medical sciences

authors： Pirtea L,Secosan C,Margan M,Moleriu L,Balint O,Grigoras D,Sas I,Horhat F,Jianu A,Ilina R

更新日期：2019-11-08 00:00:00

abstract：:Early posttraumatic epilepsies (EPTE) are epileptic attacks that appear in first seven days after brain injury, with incidence of 3-5%. Predictors for development of EPTE are: impressive skull fracture with rupture of dura, intracranial haemorrhage, neurogical deficit (brain contusion), and posttraumatic amnesia longe...

journal_title：Bosnian journal of basic medical sciences

authors： Gavranović M,Konjhodzić F,Zubcević S,Catibusić F,Uzicanin S

更新日期：2005-11-01 00:00:00

abstract：:A decision for operative versus nonoperative management of thoracolumbar fractures should NEVER be based solely on one factor. Only after a thorough physical, neurological, and spinal examination, and an assessment of a patient's prior activity, social and educational background and patient's expectations, one should ...

journal_title：Bosnian journal of basic medical sciences

authors： Karaiković EE,Pacheco HO

更新日期：2005-05-01 00:00:00

abstract：:There are numerous methods of administering drugs to the body, both passive and active. Active methods include the use of penetration enhancers and assisted drug delivery. One of them is sonophoresis (phonophoresis). This term is used to describe the effects of ultrasound on the movement of drugs through intact living...

journal_title：Bosnian journal of basic medical sciences

authors： Vranić E

更新日期：2004-05-01 00:00:00

abstract：:Aim of this study was to evaluate the biotransformation of simple phenols after ingestion of edible fruits and mixed food. It was analyzed hippuric acid in urine as biomarker of conjugation in the liver cells of glycine with aromatic phenolic acids such benzoic and salicylic acid from ingested food. Measurement of hip...

journal_title：Bosnian journal of basic medical sciences

authors： Toromanović J,Kovac-Besović E,Sapcanin A,Tahirović I,Rimpapa Z,Kroyer G,Sofić E

更新日期：2008-02-01 00:00:00

abstract：:Trefoil Factor Family (TFF) plays an essential role in the intestinal epithelial restitution, but the relationship between TFF1 and gastric cancer (GC) is still unclear. The present study aimed to determine the role of TFF1 in repairing gastric mucosa and in the pathogenesis of GC. The TFF1 expression in different ga...

journal_title：Bosnian journal of basic medical sciences

authors： Ge Y,Zhang J,Cao J,Wu Q,Sun L,Guo L,Wang Z

更新日期：2012-05-01 00:00:00

abstract：:Physical capacity of athletes is an important element of success in sports achievements. Aerobic capacity has been accepted as its major component. Maximal oxygen uptake (VO2max) has been regarded by majority of authors as the best indicator of aerobic capacity of an organism, and at the same time, the best indicator ...

journal_title：Bosnian journal of basic medical sciences

authors： Rankovic G,Mutavdzic V,Toskic D,Preljevic A,Kocic M,Nedin Rankovic G,Damjanovic N

更新日期：2010-02-01 00:00:00

abstract：:As for the third age, psychophysical abilities of humans gradually decrease, while the ability of adaptation to endogenous and exogenous burdens is going down. In 1987, "Harada" et al. (1) have found out that 9.5 million persons in USA have difficulties running daily activities, while 59% of them (which is 5.6 million...

journal_title：Bosnian journal of basic medical sciences

authors： Avdić D,Pecar D

更新日期：2006-02-01 00:00:00

abstract：:Pituitary adenomas represent the third most common primary intracranial tumor in neurosurgical practice. To understand the biological behaviour of the pituitary adenomas previous studies have determined the tumor proliferation rate using monoclonal antibodies targeted against the Ki-67 antigen. The aim of this study w...

journal_title：Bosnian journal of basic medical sciences

authors： Bălinişteanu B,Cîmpean AM,Ceauşu AR,Corlan AS,Melnic E,Raica M

更新日期：2017-05-20 00:00:00