Tumor suppressive function of microRNA-192 in acute lymphoblastic leukemia.

abstract：:Structural changes in the rat placenta during the last third of gestation were for the first time assessed by stereology. Fischer female rats were euthanized on the day 16 or day 19 of gestation, and 35 placentas were collected. Three randomly selected placentas from each group were stereologically analyzed for the ab...

journal_title：Bosnian journal of basic medical sciences

authors： Serman L,Zunic I,Vrsaljko N,Grbesa D,Gjurcevic E,Matasin Z,Nikuseva Martic T,Bulic Jakus F,Tlak Gajger I,Serman A

更新日期：2015-01-22 00:00:00

abstract：:The aim of the study was to verify the presence of mutated tumor suppresser gene p53 in intestinal mucosa with histologically confirmed premalignant lesions and gastric carcinoma, and assess its prognostic value. The paper presents prospective study that included 50 patients with gastric adeno-carcinoma of intestinal ...

journal_title：Bosnian journal of basic medical sciences

authors： Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković S

更新日期：2007-02-01 00:00:00

abstract：:Pituitary adenomas represent the third most common primary intracranial tumor in neurosurgical practice. To understand the biological behaviour of the pituitary adenomas previous studies have determined the tumor proliferation rate using monoclonal antibodies targeted against the Ki-67 antigen. The aim of this study w...

journal_title：Bosnian journal of basic medical sciences

authors： Bălinişteanu B,Cîmpean AM,Ceauşu AR,Corlan AS,Melnic E,Raica M

更新日期：2017-05-20 00:00:00

abstract：:Staphylococcus aureus has long been recognized as one of the leading cause of hospital infections all over the world. Increased frequency of methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients and possibility of vancomycin resistance requires rapid and reliable characterization of isolates and ...

journal_title：Bosnian journal of basic medical sciences

authors： Ostojić M

更新日期：2008-08-01 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) with KRAS (Kirsten RAt Sarcoma 2 viral oncogene homolog) mutation has become a clinical challenge in cancer treatment as KRAS-mutant tumors are often resistant to conventional anti-tumor therapies. Activated CDC42-associated kinase 1 (ACK1), an activator of protein kinase B (AKT), is...

journal_title：Bosnian journal of basic medical sciences

authors： Yu X,Liu J,Qiu H,Hao H,Zhu J,Peng S

更新日期：2020-06-01 00:00:00

abstract：:This is the first study performed in population from Bosnia & Herzegovina (BH), in which we analysed a significance of genetic variations in drug-metabolising enzyme, cytochrome P450 (CYP), in pathogenesis of Type 2 diabetes. We have determined allele frequencies for CYP2C9*2, CYP2C19*2, and CYP2D6*4 in diabetic patie...

journal_title：Bosnian journal of basic medical sciences

authors： Semiz S,Dujic T,Ostanek B,Prnjavorac B,Bego T,Malenica M,Marc J,Causevic A

更新日期：2010-11-01 00:00:00

abstract：:Thymic stromal lymphopoietin (TSLP) is a cytokine produced by epithelial cells in the lungs, skin, and intestinal mucosa and is involved in several physiological and pathological processes. In this study, we evaluated serum TSLP levels in patients with celiac disease (CD). The prospective study was conducted at a gast...

journal_title：Bosnian journal of basic medical sciences

authors： Kahramanoğlu Aksoy E,Akpınar MY,Pirinççi Sapmaz F,Doğan Ö,Uzman M,Nazlıgül Y

更新日期：2019-08-20 00:00:00

abstract：:The aim of our study was to examine NPHS1, NPHS2, WT1 and LAMB2 mutations, previously reported in two thirds of patients with nephrotic syndrome with onset before the age of one year old. Genomic DNA samples from Polish children (n=33) with Steroid-Resistant Nephrotic Syndrome (SRNS) due to focal segmental glomerulosc...

journal_title：Bosnian journal of basic medical sciences

authors： Bińczak-Kuleta A,Rubik J,Litwin M,Ryder M,Lewandowska K,Taryma-Leśniak O,Clark JS,Grenda R,Ciechanowicz A

更新日期：2014-05-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) is a potentially preventable iatrogenic illness that may develop following mechanical ventilation. A bundle for the prevention of VAP consists of different measures which may vary between institutions, and may include: elevation of the head of the bed, oral care with chlorhexidine...

journal_title：Bosnian journal of basic medical sciences

authors： Burja S,Belec T,Bizjak N,Mori J,Markota A,Sinkovič A

更新日期：2018-02-20 00:00:00

abstract：:The aim of study was to evaluate endocrine changes in PCOS women during metformin treatment. One hundred women with PCOS, aged 20-40 years were included. A complete hormonal and metabolic pattern was recorded for each subject every 6 months. Metformin treatment after 6 and 12 months significantly reduced weight, BMI, ...

journal_title：Bosnian journal of basic medical sciences

authors： Velija-Ašimi Z

更新日期：2013-08-01 00:00:00

abstract：:We investigated serum concentration of C-reactive protein (CRP) and measures of adiposity in 30 patients with type 2 diabetes mellitus (15 male, 15 female) and 30 age and sex-matched apparently healthy subjects. CRP concentration was determined by laser nephelometry (BN II Analyzer) and CardioPhase high-sensitivity CR...

journal_title：Bosnian journal of basic medical sciences

authors： Zaciragić A,Huskić J,Hadzović-Dzuvo A,Valjevac A,Avdagić N,Mulabegović N

更新日期：2007-11-01 00:00:00

abstract：:Owing to its unique nutritional and immunological characteristics, breast milk is the most important food source for infants. But, children are at greater risk for exposure to environmental toxicants from breast milk. The aim of this study was to evaluate the influence of environmental pollution on essential and toxic...

journal_title：Bosnian journal of basic medical sciences

authors： Cinar N,Ozdemir S,Yucel O,Ucar F

更新日期：2011-11-01 00:00:00

abstract：:Innocent heart murmurs are hearth murmurs that occur in patients with a normal heart structure. They do not represent a disease of the heart and vascular system, and should not be treated as such. Iron-deficiency anaemia often causes, along with other symptoms, systolic heart murmurs and tachycardia. It appears in chi...

journal_title：Bosnian journal of basic medical sciences

authors： Mesihović-Dinarević S,Ibrahimović J,Hasanbegović E,Ićindić-Nakas E,Smajić A

更新日期：2005-08-01 00:00:00

abstract：:Primary skin melanoma and skin cancers have been more prevalent in the previous decades and therefore have become a very significant public health problem. Dermatologists of the Skin and Venereal Diseases Clinic of the University of Sarajevo Clinics Centre initiated the first public preventive action called "Days of F...

journal_title：Bosnian journal of basic medical sciences

authors： Alendar F,Drljević I,Drljević K,Alendar T

更新日期：2009-02-01 00:00:00

abstract：:The aim of the study was to ascertain presence of Helicobacter pylori in gastric carcinoma as a responsible promoter of inflammatory-regenerative changes, which lead to pathological differentiation and transformation of normal epithelial cells into intestinal type and, in progression, cause epithelial dysplasia that d...

journal_title：Bosnian journal of basic medical sciences

authors： Vukobrat-Bijedić Z,Radović S,Husić-Selimović A,Gornjaković S

更新日期：2006-08-01 00:00:00

abstract：:Neutral red is a dye the azine structure which has been used as an acido-base indicator and a dye in histochemistry. In 1960 Goldhaber introduced Neutral red into the medium of resorbing bone cultures to localize the osteoclast in the living cultures. Using time-lapse microcinematography in order to follow the osteocl...

journal_title：Bosnian journal of basic medical sciences

authors： Rimpapa Z,Sofić E,Sapcanin A,Toromanović J,Tahirović I

更新日期：2007-02-01 00:00:00

abstract：:Atherosclerosis is a pathological condition that begins in early childhood, but clinically the disease manifests in older age. The aim of work was to determine frequency of atherosclerosis risk factors in healthy school children. Cross-sectional study included 214 children in mean age 10,99+/-2,52 years, within range ...

journal_title：Bosnian journal of basic medical sciences

authors： Sporisević L,Krzelj V,Bajraktarević A,Jahić E

更新日期：2009-08-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is an uncommon soft tissue sarcoma that originates from the dermis or subcutaneous tissue in the skin. While its prognosis is generally favorable, disease recurrence is relatively frequent. Because morbidity after repeated surgery may be significant, an optimized prediction of re...

journal_title：Bosnian journal of basic medical sciences

authors： Adem D,Yazici S,Ozsen M,Cetintas SK,Yalcinkaya U,Şahin AB,Tanrıverdi O,Orhan SO,Ocak B,Cubukcu E,Kahveci R,Evrensel T

更新日期：2020-10-20 00:00:00

abstract：:Neonatal BCG vaccination reduces the risk of tuberculosis and provides protection higher than 80% against the development of meningeal and miliary tuberculosis in newborns. Tuberculosis meningitis remains a major problem and also an important cause of death in some countries. In countries with high and moderate incide...

journal_title：Bosnian journal of basic medical sciences

authors： Puvacić S,Dizdarević J,Santić Z,Mulaomerović M

更新日期：2004-02-01 00:00:00

abstract：:Aminoglycoside antibiotics are obligated nephrotoxins and inevitably cause renal failure during prolonged use. Experimental models of gentamicin-induced nephrotoxicity have shown histopathological, ultrastructural and functional alteration with blood urea nitrogen and serum creatinine increase leading to acute renal i...

journal_title：Bosnian journal of basic medical sciences

authors： Stojiljković N,Veljković S,Mihailović D,Stoiljković M,Radovanović D,Randelović P

更新日期：2008-05-01 00:00:00

abstract：:The blockade of peripheral nerves carries a certain risk of unwanted complications, which can follow after unintentional intraneural injection of a local anesthetic. Up till today, the research of measuring injection pressure has been based on animal models, even though the histological structure of periphery nerve is...

journal_title：Bosnian journal of basic medical sciences

authors： Vucković I,Dilberović F,Kulenović A,Divanović KA,Voljevica A,Kapur E

更新日期：2006-11-01 00:00:00

abstract：:The objective of our study was to evaluate bladder outlet obstruction number (BOON) in order to predict infravesical obstruction in patients with benign prostatic enlargement (BPE). Two hundred patients with proven BPE from daily urological practice at the Urology Department of the Sarajevo University Clinical Centre ...

journal_title：Bosnian journal of basic medical sciences

authors： Aganovic D,Spahovic H,Prcic A,Hadziosmanovic O

更新日期：2012-08-01 00:00:00

abstract：:Amorphous forms are, by definition, non-crystalline materials which possess no long-range order. Their structure can be thought of as being similar to that of a frozen liquid with the thermal fluctuations present in a liquid frozen out, leaving only "static" structural disorder. The amorphous solids have always been a...

journal_title：Bosnian journal of basic medical sciences

authors： Vranić E

更新日期：2004-07-01 00:00:00

abstract：:Valsartan (VAL), an antagonist of angiotensin II receptor type 1, has antihypertensive and multiple cardiovascular protective effects. The pleiotropic functions of VAL are related to the increased synthesis and biological activity of intravascular nitric oxide (NO). In this study, the role and mechanisms of VAL in the...

journal_title：Bosnian journal of basic medical sciences

authors： Zhao Y,Wang L,He S,Wang X,Shi W

更新日期：2017-05-20 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been implicated in numerous biological processes, including epigenetic regulation, cell-cycle control, and transcriptional/translational regulation of gene expression. Differential expression of lncRNAs and disruption of the regulatory processes are recognized as critical steps in c...

journal_title：Bosnian journal of basic medical sciences

authors： Yılmaz Susluer S,Kayabasi C,Ozmen Yelken B,Asik A,Celik D,Balci Okcanoglu T,Serin Senger S,Biray Avci C,Kose S,Gunduz C

更新日期：2018-05-20 00:00:00

abstract：:Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental tissue remains mostly unknown. In the current study, we explored the role of Dishevelled proteins in...

journal_title：Bosnian journal of basic medical sciences

authors： Sola IM,Serman A,Karin-Kujundzic V,Paic F,Skrtic A,Slatina P,Kakarigi L,Vranic S,Serman L

更新日期：2020-12-26 00:00:00

abstract：:Stability testing of an active substance or finished product provides information of the variation of drug substance or final product with time influenced by a variety of environmental factors such as temperature, humidity and light. Knowledge gained from stability studies enables understanding of the effects of the e...

journal_title：Bosnian journal of basic medical sciences

authors： Uzunović A,Vranić E

更新日期：2008-02-01 00:00:00

abstract：:Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women. p16/Ki-67 dual immunocytochemical staining can also be used for the detection of oncogenic changes in cervical cells. Our aim was to compare the perform...

journal_title：Bosnian journal of basic medical sciences

authors： Pirtea L,Secosan C,Margan M,Moleriu L,Balint O,Grigoras D,Sas I,Horhat F,Jianu A,Ilina R

更新日期：2019-11-08 00:00:00

abstract：:Tocotrienol rich fraction (TRF) is an extract of palm oil, which consists of 25% alpha tocopherol (α-TCP) and 75% tocotrienols. TRF has been shown to possess potent antioxidant, anti-inflammatory, anticancer, neuroprotection, and cholesterol lowering activities. Glutamate is the main excitatory amino acid neurotransmi...

journal_title：Bosnian journal of basic medical sciences

authors： Selvaraju TR,Khaza'ai H,Vidyadaran S,Abd Mutalib MS,Vasudevan R

更新日期：2014-11-16 00:00:00

abstract：:Colloid cysts are benign intracranial tumours usually occurring in the front part of the third ventricle. Clinical presentation may be non-specific and heterogeneous. The problems are frequently associated with development of hydrocephalus, these cysts may cause. We describe three cases of patients with diverse clinic...

journal_title：Bosnian journal of basic medical sciences

authors： Ravnik J,Bunc G,Grcar A,Zunic M,Velnar T

更新日期：2014-08-14 00:00:00